Working In Biosafety Level 3 And 4 Laboratories

Author : Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 41,8 Mb
Release : 2013-12-04
Category : Science
ISBN : 352733467X

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Working in Biosafety Level 3 and 4 Laboratories by Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner Pdf

The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.

Author : Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner
Publisher : John Wiley & Sons
Page : 176 pages
File Size : 53,7 Mb
Release : 2013-09-18
Category : Science
ISBN : 9783527675333

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Working in Biosafety Level 3 and 4 Laboratories by Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner Pdf

The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.

Author : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council
Publisher : National Academies Press
Page : 216 pages
File Size : 41,5 Mb
Release : 2012-03-16
Category : Political Science
ISBN : 9780309225762

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Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council Pdf

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Author : World Health Organization
Publisher : World Health Organization
Page : 196 pages
File Size : 47,6 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9241546506

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Laboratory Biosafety Manual by World Health Organization Pdf

This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

Author : Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council
Publisher : National Academies Press
Page : 237 pages
File Size : 47,8 Mb
Release : 1989-01-01
Category : Science
ISBN : 9780309039758

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Biosafety in the Laboratory by Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council Pdf

Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.

Author : Margaret R. O'Leary
Publisher : iUniverse
Page : 565 pages
File Size : 44,5 Mb
Release : 2004
Category : Disaster relief
ISBN : 9780595310845

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The First 72 Hours by Margaret R. O'Leary Pdf

The First 72 Hours is the seminal anthology of the perspectives of public and private sector leaders who came together after September 11, 2001 to design more disaster-resilient communities. Under the umbrella of the Suburban Emergency Management Project, these leaders learned from national experts and one another that all disasters are intensely local at first and that most communities are "on their own" immediately following disaster impact--often for as long as 72 hours. This new awareness mandated updating strategies to improve disaster preparedness, particularly in light of the threat of terrorism. A wide gamut of perspectives are laid out in the book, including those of doctors and hospitals, city managers, police officers, firefighters, paramedics, American Red Cross volunteers, hospital accreditors, the media, business managers, utility companies, emergency managers, public health officials, academics, and elected public officials. In their own words, these individuals convey the importance of learning how to map the myriad organizations involved in local disaster preparedness and response; analyzing, refining and rehearsing local disaster roles; and getting to know individual personalities when in specific roles. The First 72 Hours is an essential resource for professionals and private citizens alike who want to know what kinds of questions must be asked and answered to better prepare their communities to survive future disaster. "There's a special providence in the fall of a sparrow. If it be now, 'tis not to come; if it be not to come, it will be now; if it be not now, yet it will come: the readiness is all."--Hamlet V, II, William Shakespeare

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs
Publisher : National Academies Press
Page : 121 pages
File Size : 51,8 Mb
Release : 2019-05-01
Category : Science
ISBN : 9780309486569

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Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs Pdf

On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop.

Author : Centers for Disease Control (U.S.)
Publisher : Unknown
Page : 156 pages
File Size : 49,8 Mb
Release : 1988
Category : Accidents
ISBN : WISC:89030643761

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Biosafety in Microbiological and Biomedical Laboratories by Centers for Disease Control (U.S.) Pdf

Author : Mary Louise Turgeon
Publisher : Elsevier Health Sciences
Page : 797 pages
File Size : 40,6 Mb
Release : 2022-09-14
Category : Medical
ISBN : 9780323832212

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Clinical Laboratory Science - E-Book by Mary Louise Turgeon Pdf

Using a discipline-by-discipline approach, Turgeon’s Clinical Laboratory Science: Concepts, Procedures, and Clinical Applications, 9th Edition, provides a fundamental overview of the concepts, procedures, and clinical applications essential for working in a clinical laboratory and performing routine clinical lab tests. Coverage includes basic laboratory techniques and key topics such as safety, phlebotomy, quality assessment, automation, and point-of-care testing, as well as discussion of clinical laboratory specialties. Clear, straightforward instructions simplify laboratory procedures and are guided by the latest practices and CLSI (Clinical and Laboratory Standards Institute) standards. Written by well-known CLS educator Mary Louise Turgeon, this edition offers essential guidance and recommendations for today’s laboratory testing methods and clinical applications. Broad scope of coverage makes this text an ideal companion for clinical laboratory science programs at various levels, including CLS/MT, CLT/MLT, medical laboratory assistant, and medical assisting, and reflects the taxonomy levels of the CLS/MT and CLT/MLT exams. Detailed procedure guides and procedure worksheets on Evolve and in the ebook familiarize you with the exact steps performed in the lab. Vivid, full-color illustrations depict concepts and applicable images that can be seen under the microscope. An extensive number of certification-style, multiple-choice review questions are organized and coordinated under major topical headings at the end of each chapter to help you assess your understanding and identify areas requiring additional study. Case studies include critical thinking group discussion questions, providing the opportunity to apply content to real-life scenarios. The newest Entry Level Curriculum Updates for workforce entry, published by the American Society for Clinical Laboratory Science (ASCLS) and the American Society for Clinical Pathology (ASCP) Board of Certification Exam Content Outlines, serve as content reference sources. Convenient glossary makes it easy to look up definitions without having to search through each chapter. An Evolve companion website provides convenient access to animations, flash card sets, and additional review questions. Experienced author, speaker, and educator Mary L. Turgeon is well known for providing insight into the rapidly changing field of clinical laboratory science.

Author : Donna Larson
Publisher : Elsevier Health Sciences
Page : 739 pages
File Size : 40,6 Mb
Release : 2015-12-17
Category : Medical
ISBN : 9780323292535

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Clinical Chemistry - E-Book by Donna Larson Pdf

Gain a clear understanding of pathophysiology and lab testing! Clinical Chemistry: Fundamentals and Laboratory Techniques prepares you for success as a medical lab technician by simplifying complex chemistry concepts and lab essentials including immunoassays, molecular diagnostics, and quality control. A pathophysiologic approach covers diseases that are commonly diagnosed through chemical tests — broken down by body system and category — such as respiratory, gastrointestinal, and cardiovascular conditions. Written by clinical chemistry educator Donna Larson and a team of expert contributors, this full-color book is ideal for readers who may have minimal knowledge of chemistry and are learning laboratory science for the first time. Full-color illustrations and design simplify complex concepts and make learning easier by highlighting important material. Case studies help you apply information to real-life scenarios. Pathophysiology and Analytes section includes information related to diseases or conditions, such as a biochemistry review, disease mechanisms, clinical correlation, and laboratory analytes and assays. Evolve companion website includes case studies and animations that reinforce what you’ve learned from the book. Laboratory Principles section covers safety, quality assurance, and other fundamentals of laboratory techniques. Review questions at the end of each chapter are tied to the learning objectives, helping you review and retain the material. Critical thinking questions and discussion questions help you think about and apply key points and concepts. Other Aspects of Clinical Chemistry section covers therapeutic drug monitoring, toxicology, transplantation, and emergency preparedness. Learning objectives in each chapter help you to remember key points or to analyze and synthesize concepts in clinical chemistry. A list of key words Is provided at the beginning of each chapter, and these are also bolded in the text. Chapter summaries consist of bulleted lists and tables highlighting the most important points of each chapter. A glossary at the back of the book provides a quick reference to definitions of all clinical chemistry terms.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Agriculture and Natural Resources,Committee on an Analysis of the Requirements and Alternatives for Foreign Animal and Zoonotic Disease Research and Diagnostic Laboratory Capabilities
Publisher : National Academies Press
Page : 144 pages
File Size : 41,5 Mb
Release : 2012-10-28
Category : Technology & Engineering
ISBN : 9780309261296

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Meeting Critical Laboratory Needs for Animal Agriculture by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Agriculture and Natural Resources,Committee on an Analysis of the Requirements and Alternatives for Foreign Animal and Zoonotic Disease Research and Diagnostic Laboratory Capabilities Pdf

Outbreaks of animal disease can have catastrophic repercussions for animal agriculture, the food supply, and public health. Rapid detection, diagnosis and response, as well as development of new vaccines, are central to mitigating the impact of disease outbreaks. The proposed National Bio- and Agro-Defense Facility (NBAF) is a next-generation laboratory for animal disease diagnostics, training, and research that would provide core critical components for defense against foreign animal and zoonotic disease threats. But it will be a major investment with estimated construction costs of $1.14 billion, as currently designed. Meeting Critical Laboratory Needs for Animal Agriculture: Examination of Three Optionsdiscusses the laboratory infrastructure needed to effectively address the threat posed by animal and zoonotic diseases and analyzes three options for creating this infrastructure: building NBAF as currently designed, building a scaled-back version of the NBAF, or maintaining current research capabilities at Plum Island Animal Disease Center while leveraging biosafety level-4 large animal capabilities at foreign laboratories.

Author : Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy
Publisher : Springer
Page : 527 pages
File Size : 51,7 Mb
Release : 2016-10-22
Category : Technology & Engineering
ISBN : 9789811008757

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Basic and Applied Aspects of Biotechnology by Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy Pdf

This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.

Author : Canada. Health Canada,Centre for Emergency Preparedness and Response (Canada)
Publisher : Unknown
Page : 134 pages
File Size : 51,6 Mb
Release : 2004
Category : Medical
ISBN : UIUC:30112074022465

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The Laboratory Biosafety Guidelines by Canada. Health Canada,Centre for Emergency Preparedness and Response (Canada) Pdf

These guidelines were developed to guide government, industry, university, hospital, and other public health and microbiological laboratories in their development of biosafety policies and programs. They also provide information and recommendations on the design, construction, and commissioning of containment facilities. The guidelines are intended to reduce the incidence of infection and mortality among laboratory workers, as well as to prevent secondary transmission of disease to the public.

Author : J. Thompson,S. Gahlaut
Publisher : IOS Press
Page : 165 pages
File Size : 52,7 Mb
Release : 2015-09-03
Category : Political Science
ISBN : 9781614995340

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CBRN Security Culture in Practice by J. Thompson,S. Gahlaut Pdf

Evolving threats of chemical, biological, radiological and nuclear (CBRN) attack make it imperative to find ways to support global efforts against the proliferation of weapons of mass destruction (WMD) and terrorism. This book contains papers presented at the NATO Advanced Study Institute (ASI) on CBRN security culture, held in Yerevan, Armenia, in June 2014. The conference was timely in bringing together the various aspects of security culture in the different substantive areas from a CBRN perspective, focusing efforts to advance CBRN security culture in the everyday work of those who must deal with these ever present threats. The primary aim of the conference was to promote the concept of a CBRN security culture which recognizes synergy across the individual disciplines. As a first step in the practical application of this synergistic view, the conference introduced assessment methodologies that could be refined and customized to enhance the role of the human factor in CBRN security. This, we hope, will enable countries to fulfill their international obligations and implement United Nations Security Council Resolution 1540. The book reflects the presentations and deliberations of workshop participants and will be of interest to governments, international organizations, researchers and practitioners whose work involves the human dimension of the security of CBRN materials.

Author : Anonim
Publisher : Unknown
Page : 40 pages
File Size : 47,8 Mb
Release : 1988
Category : AIDS (Disease)
ISBN : UCSD:31822017306077

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Working Safely with HIV in the Research Laboratory by Anonim Pdf