Biotechnology In Industry

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Industrialization of Biology

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals
Publisher : National Academies Press
Page : 167 pages
File Size : 48,9 Mb
Release : 2015-06-29
Category : Science
ISBN : 9780309316552

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Industrialization of Biology by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals Pdf

The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

Industrial Biotechnology

Author : Christoph Wittmann,James C. Liao
Publisher : John Wiley & Sons
Page : 642 pages
File Size : 44,6 Mb
Release : 2017-03-06
Category : Science
ISBN : 9783527341818

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Industrial Biotechnology by Christoph Wittmann,James C. Liao Pdf

The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.

Industrial Biotechnology

Author : Devarajan Thangadurai,Jeyabalan Sangeetha
Publisher : CRC Press
Page : 277 pages
File Size : 55,7 Mb
Release : 2017-03-03
Category : Science
ISBN : 9781315342375

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Industrial Biotechnology by Devarajan Thangadurai,Jeyabalan Sangeetha Pdf

This important new book covers recent advancements, innovations, and technologies in industrial biotechnology, specifically addressing the application of various biomolecules in industrial production and in cleaning and environmental remediation sectors. The goal of industrial biotechnology is to develop new techniques and technologies to transform renewable raw materials into chemicals, materials, and fuels by the substitution of fossil fuels. With the increase in the world’s population and the resultant growing energy demand, the need for more energy can be successfully met with the advancements in industrial biotechnology. Currently across the globe significant research has been undertaken in the production of cleaner fuels, materials, and semi-synthetic chemicals, with environmental benefits. Developing countries have huge agricultural resources that could be utilized for production of value-added byproducts for the sustainable development of bio-based economy. The book opens with the chapter on the production of exopolysaccharides from halophilic microorganisms, a polymer that is normally very useful in various production sectors of the food, pharmaceutical, and petroleum industries. The book goes on to cover: The production of antimicrobial compounds from alkaliphilic bacteria Thermophilic actinomycetes Food, agro, and pharmaceutical potential and biotechnological applications of biosurfactants, halophiles, cyclodextrin glycosyl transferease, fungal chitinase, proteases, yeasts and yeast products Also covered in the book are the environmental aspects of industrial biotechnology such as the genetic enhancement for biofuel production, the production of biodegradable thermoplastics, advancements in the synthesis of bio-oil, ecofriendly treatment of agro-based lignocelluloses, and anaerobic bio reactors for hydrocarbon remediation. The international roster of chapter authors have been chosen for their renowned expertise and contribution to the various fields of industrial biotechnology. This book is suitable to chemists, biotechnologists from research institutes, academia, and students as well as for industry professionals

Advances in Biotechnology for Food Industry

Author : Alexandru Mihai Grumezescu,Alina Maria Holban
Publisher : Academic Press
Page : 508 pages
File Size : 47,8 Mb
Release : 2018-02-03
Category : Technology & Engineering
ISBN : 9780128114957

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Advances in Biotechnology for Food Industry by Alexandru Mihai Grumezescu,Alina Maria Holban Pdf

Advances in Biotechnology for Food Industry, Volume Fourteen in the Handbook of Food Bioengineering series, provides recent insight into how biotechnology impacts the global food industry and describes how food needs are diverse, requiring the development of innovative biotechnological processes to ensure efficient food production worldwide. Many approaches were developed over the last 10 years to allow faster, easier production of widely used foods, food components and therapeutic food ingredients. This volume shows how biotechnological processes increase production and quality of food products, including the development of anti-biofilm materials to decrease microbial colonization in bioreactors and food processing facilities. Presents basic to advanced technological applications in food biotechnology Includes various scientific techniques used to produce specific desired traits in plants, animals and microorganisms Provides scientific advances in food processing and their impact on the environment, human health and food safety Discusses the development of controlled co-cultivations for reproducible results in fermentation processes in food biotechnology

Maintaining Cultures for Biotechnology and Industry

Author : Jennie C. Hunter-Cevera,Angela Belt
Publisher : Elsevier
Page : 263 pages
File Size : 44,5 Mb
Release : 1996-02-21
Category : Science
ISBN : 0080535755

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Maintaining Cultures for Biotechnology and Industry by Jennie C. Hunter-Cevera,Angela Belt Pdf

To retain their usefulness, cultures that manufacture economically valuable products must be uncontaminated, viable, and genetically stable. Maintaining Cultures for Biotechnology and Industry gives practical advice necessary to preserve and maintain cells and microorganisms important to the biotechnology and pharmaceutical industries in ways that ensure they will continue to be able to synthesize those valuable metabolites. This book covers not just those strains currently being used but also those yet to be discovered and engineered. This text is essential for anyone working with cultures who wants to avoid the frustration of losing strains and needs to be able to devise and evaluate new strategies for preservation. Written by hands-on experts in their respective fields Contains helpful tables and protocols for preserving or maintaining cells, cultures and viruses Discusses means to preserve cells by freezing, lyophilization, drying, cyoprotection, spore storage, continuous propagation and subculturing when absolutely necessary, and others Gives information needed to test cultures for stable retention of important characteristics Gives principles needed to devise and evaluate preservation strategies for newly identified and newly engineered cells and organisms Lists culture sources for each class of organism Includes information for characterizing and monitoring recombinant organisms, especially important because of their propensity for genetic stability Discusses the history of the continually evolving field of culture preservation Examines the importance of genetically stable cultures as it relates to maintaining patent positions

Sustainability and Life Cycle Assessment in Industrial Biotechnology

Author : Magnus Fröhling,Michael Hiete
Publisher : Springer Nature
Page : 363 pages
File Size : 54,5 Mb
Release : 2020-06-16
Category : Science
ISBN : 9783030470661

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Sustainability and Life Cycle Assessment in Industrial Biotechnology by Magnus Fröhling,Michael Hiete Pdf

This book reviews the assessment of industrial biotechnology products and processes from a sustainable perspective. Industrial Biotechnology is a comparably young field which comes along with high expectations with regard to sustainability issues. These stem from the promise of reducing greenhouse gas emissions and replacing fossil resources in the near or later future and using green technology, i.e. more environmentally friendly technologies. The intended economic, ecological and social benefits, however, need to be proven, resulting in a variety of challenges, both from a methodological and application point of view. In this book, specific assessment and application topics of industrial biotechnology are addressed, highlighting challenges and solutions for both developers and users of assessment methods. In twelve chapters, experts in their particular fields define the scope, characterize industrial biotechnology and show in their contributions the state of the art, challenges and prospects of assessing industrial biotechnology products and processes. The chapter 'Societal and Ethical Aspects of Industrial Biotechnology' of this book is available open access under a CC BY 4.0 license at link.springer.com

Future Prospects for Industrial Biotechnology

Author : OECD
Publisher : OECD Publishing
Page : 142 pages
File Size : 47,9 Mb
Release : 2011-09-16
Category : Electronic
ISBN : 9789264126633

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Future Prospects for Industrial Biotechnology by OECD Pdf

This publication examines the international drivers, the enabling technologies that are fast-tracking Industrial Biotechnology, industry trends, some of the products that are appearing on the market, industry structure and finance, and finally policy measures and trends.

From Breakthrough to Blockbuster

Author : Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos
Publisher : Oxford University Press
Page : 241 pages
File Size : 54,7 Mb
Release : 2022
Category : Biotechnology industries
ISBN : 9780195084009

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From Breakthrough to Blockbuster by Donald L. Drakeman,Lisa N. Drakeman,Nektarios Oraiopoulos Pdf

"Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--

Industrial Biotechnology

Author : Debabrata Das,Soumya Pandit
Publisher : CRC Press
Page : 501 pages
File Size : 52,9 Mb
Release : 2021-05-06
Category : Science
ISBN : 9781000382297

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Industrial Biotechnology by Debabrata Das,Soumya Pandit Pdf

Exposes readers to various biochemical industries Analyzes problems within biochemical processes Discusses stoichiometry of bioprocesses Covers upstream and downstream processing Offers a wealth of case studies of different biochemical production processes, including those in development of food products, vaccines and medicines, single cell proteins, amino acids, cheese, biodiesel, biopesticides, and more

Industrial Biotechnology

Author : Loveleen Kaur
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 49,9 Mb
Release : 2015
Category : Biotechnology industries
ISBN : 1634638476

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Industrial Biotechnology by Loveleen Kaur Pdf

Industrial biotechnology can be defined as the use of modern biological life sciences in various industries. Biotechnology has a myriad of applications in our day to day life such as with simple processes such as the brewing of beer, use of enzymes in detergents, production of fermented food, production of antibiotics, nutritional supplements etc. This book also includes processes (production of biofuels, treatment of effluents) that contribute to creating efficient, eco-friendly environments. This book discusses the different aspects of bioprocesses; media design, fermenter design and the economics of it. It also explains in detail the processes and techniques involved in the production of commercially important products. This book is an up-to-date collection of the latest practices being followed in the field of industrial biotechnology for students both at the undergraduate and postgraduate level.

Biotechnology Entrepreneurship

Author : Craig Shimasaki
Publisher : Academic Press
Page : 489 pages
File Size : 51,7 Mb
Release : 2014-04-08
Category : Medical
ISBN : 9780124047471

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Biotechnology Entrepreneurship by Craig Shimasaki Pdf

As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a ‘how-to’ for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars Case studies are interspersed throughout each chapter to support key concepts and best practices. Enhanced by use of numerous detailed graphics, tables and flow charts

Biosafety in Industrial Biotechnology

Author : P. Hambleton,T. Salusbury
Publisher : Springer Science & Business Media
Page : 317 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401113526

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Biosafety in Industrial Biotechnology by P. Hambleton,T. Salusbury Pdf

As an industry, biotechnology may be likened to the Hymn Book, being both ancient and modern. Whereas activities such as baking, brewing, the fermenting of foods date from our earliest attempts to control and utilise the environment, the application of recombinant DNA technology is recognised as being at the forefront of novel industrial development. Perhaps because of its association with processing foodstuffs together with the benefits derived from applications in the early organic chemistry and pharmaceutical industries, biotechnology has been regarded as being inherently safe. Yet unlike other modern industries, such as chemical and nuclear, where regulation has followed from incidents or accidents, modern biotechnology has been subject to close scrutiny and regulation almost from its inception. The process of regulation itself is somewhat unusual in that it was initially self-imposed by the very scientists who developed the fundamental techniques of recombinant DNA technology. They recognised the signific ance of their development but were concerned of the effects on humans and the environment of uncontrolled application of the new, powerful technology. Concern about the possible consequences of genetic manipula tion has undoubtedly been the driving force behind the regulations that are now in place in many parts of the world and which are the subject of this book. Safety issues in the biotechnology industry can be categorised under three headings: worker, environmental and consumer (product) safety.

Biotechnology in the Chemical Industry

Author : Pratima Bajpai
Publisher : Elsevier
Page : 246 pages
File Size : 50,9 Mb
Release : 2019-11-08
Category : Technology & Engineering
ISBN : 9780128184035

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Biotechnology in the Chemical Industry by Pratima Bajpai Pdf

Biotechnology in the Chemical Industry: Towards a Green and Sustainable Future focuses on achievements and prospects for biotechnology in sustainable production of goods and services, especially those that are derived at present mostly from the traditional chemical industry. It considers the future impact of industrial biotechnology and lays out the major research areas which must be addressed to move from a flourishing set of scientific disciplines to a major contributor to a successful future knowledge-based economy. The book focuses on the research needed to underpin three broad topics: biomass, bio-processes and bio-products, including bio-energy. Readers, including advanced students, researchers, industry professionals, academics, analysts, consultants, and anyone else interested, or involved in biotechnology will find this book very informative. Offers a comprehensive introduction to the subject for researchers interested in the biotechnological applications in chemical industry Provides a state-of-the art update on the field Presents the economic and ecological advantages of industrial biotechnology Discusses efforts made by developing countries towards industrial biotechnology Describes new biotechnological applications Includes the major challenges facing industrial biotechnology

Biotechnology for Agro-Industrial Residues Utilisation

Author : Poonam Singh-Nee Nigam,Ashok Pandey
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 52,5 Mb
Release : 2009-05-19
Category : Medical
ISBN : 9781402099427

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Biotechnology for Agro-Industrial Residues Utilisation by Poonam Singh-Nee Nigam,Ashok Pandey Pdf

Residues from agriculture and the food industry consist of many and varied wastes, in total accounting for over 250 million tonnes of waste per year in the UK alone. Biotechnological processing of these residues would allow these waste products to be used as a resource, with tremendous potential. An extensive range of valuable and usable products can be recovered from what was previously considered waste: including fuels, feeds and pharmaceutical products. In this way Biotechnology can offer many viable alternatives to the disposal of agricultural waste, producing several new products in the process. This book presents up-to-date information on a biotechnology approach for the utilisation of agro-industrial residues, presenting chapters with detailed information on materials and bioconversion technology to obtain products of economic importance: The production of industrial products using agro-industrial residues as substrates The biotechnological potential of agro-industrial residues for bioprocesses Enzymes degrading agro-industrial residues and their production Bioconversion of agro-industrial residues. Written by experts in Biotechnological processing of Agro-Industrial Residues, this book will provide useful information for academic researchers and industry scientists working in biotechnology, waste management, agriculture and the food industry.

Downstream Industrial Biotechnology

Author : Michael C. Flickinger
Publisher : John Wiley & Sons
Page : 884 pages
File Size : 47,6 Mb
Release : 2013-07-17
Category : Science
ISBN : 9781118618981

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Downstream Industrial Biotechnology by Michael C. Flickinger Pdf

DOWNSTREAM INDUSTRIAL BIOTECHNOLOGY An affordable, easily accessible desk reference on biomanufacturing, focused on downstream recovery and purification Advances in the fundamental knowledge surrounding biotechnology, novel materials, and advanced engineering approaches continue to be translated into bioprocesses that bring new products to market at a significantly faster pace than most other industries. Industrial scale biotechnology and new manufacturing methods are revolutionizing medicine, environmental monitoring and remediation, consumer products, food production, agriculture, and forestry, and continue to be a major area of research. The downstream stage in industrial biotechnology refers to recovery, isolation, and purification of the microbial products from cell debris, processing medium and contaminating biomolecules from the upstream process into a finished product such as biopharmaceuticals and vaccines. Downstream process design has the greatest impact on overall biomanufacturing cost because not only does the biochemistry of different products ( e.g., peptides, proteins, hormones, antibiotics, and complex antigens) dictate different methods for the isolation and purification of these products, but contaminating byproducts can also reduce overall process yield, and may have serious consequences on clinical safety and efficacy. Therefore downstream separation scientists and engineers are continually seeking to eliminate, or combine, unit operations to minimize the number of process steps in order to maximize product recovery at a specified concentration and purity. Based on Wiley’s Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, this volume features fifty articles that provide information on down- stream recovery of cells and protein capture; process development and facility design; equipment; PAT in downstream processes; downstream cGMP operations; and regulatory compliance. It covers: Cell wall disruption and lysis Cell recovery by centrifugation and filtration Large-scale protein chromatography Scale down of biopharmaceutical purification operations Lipopolysaccharide removal Porous media in biotechnology Equipment used in industrial protein purification Affinity chromatography Antibody purification, monoclonal and polyclonal Protein aggregation, precipitation and crystallization Freeze-drying of biopharmaceuticals Biopharmaceutical facility design and validation Pharmaceutical bioburden testing Regulatory requirements Ideal for graduate and advanced undergraduate courses on biomanufacturing, biochemical engineering, biopharmaceutical facility design, biochemistry, industrial microbiology, gene expression technology, and cell culture technology, Downstream Industrial Biotechnology is also a highly recommended resource for industry professionals and libraries.