Breast Cancer Current Trends In Molecular Research

Author : Shankar Suman
Publisher : Bentham Science Publishers
Page : 287 pages
File Size : 48,9 Mb
Release : 2022-07-18
Category : Medical
ISBN : 9781681089539

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Breast Cancer: Current Trends in Molecular Research by Shankar Suman Pdf

Breast cancer is one of the most common cancer types worldwide, and is a leading cause of cancer related deaths in women. In this book, medical experts review our current understanding of the molecular biology and characteristics of breast cancer. The topics covered in this book provide comprehensive knowledge of mechanisms underlying breast carcinogenesis, and are intended for a wide audience including scientists, teachers, and students. 11 chapters present information about several topics on breast cancer, including the role of cell growth and proliferation pathways, androgen and cytokine signaling, germline mutations in breast cancer susceptibility genes, and molecular factors causing invasive and metastatic breast cancer. In addition, the editors discuss the recent advancements in multi-omics data analysis based on inter-and intra-tumor molecular profiles. The reference highlights how the knowledge and understanding of the biological behavior of breast neoplasms have facilitated ongoing investigations into dietary polyphenolic compounds with antioxidant properties, making them function as cancer chemopreventive agents. Along with this, the current development of treatment strategies such as targeted molecular therapy, and radiation therapy is brought to the fore to update readers.

Author : Shankar Suman,Garima Suman,Sanjay Mishra
Publisher : Bentham Science Publishers
Page : 401 pages
File Size : 53,5 Mb
Release : 2020-04-30
Category : Medical
ISBN : 9789811451423

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Current Advances in Breast Cancer Research: A Molecular Approach by Shankar Suman,Garima Suman,Sanjay Mishra Pdf

Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments for the efficient management of breast cancer are now in demand , as they help to prolong patient life. There have been many breakthrough developments in the molecular biology of breast cancer research in recent times. Advancements in diagnostic techniques (imaging and biomarker detection) for breast cancer have improved the screening of the disease and have improved patient outcomes. Despite these enhancements, the disease is still lethal for patients and the search for a cure requires a complete understanding of the disease. Current Advances in Breast Cancer Research: A Molecular Approach presents a comprehensive overview of current basic and translational research on the subject. The 14 chapters of the book give emphasis to current knowledge about breast cancer, ongoing challenges, and innovative research findings by different research groups. Readers will find detailed information about breast cancer biology, genetics, clinical diagnostics and treatments. Additional information for advanced readers in life sciences, such as techniques relevant to genomics (including genetic fingerprinting), proteomics, metabolomics and medicine (such as imaging and molecular diagnostics) is also provided. The combination of both basic and advanced information makes this book a useful reference to the student and researcher, alike, seeking an understanding about breast cancer at a molecular level.

Author : Shankar Suman
Publisher : Unknown
Page : 402 pages
File Size : 54,9 Mb
Release : 2020-06
Category : Medical
ISBN : 1681087715

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Current Advances in Breast Cancer Research: A Molecular Approach by Shankar Suman Pdf

Author : Robert B. Dickson,Marc E. Lippman
Publisher : Springer Science & Business Media
Page : 446 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461535003

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Genes, Oncogenes, and Hormones by Robert B. Dickson,Marc E. Lippman Pdf

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current di agnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Author : Heide Schatten
Publisher : Springer Science & Business Media
Page : 383 pages
File Size : 48,9 Mb
Release : 2013-09-27
Category : Science
ISBN : 9781627036344

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Cell and Molecular Biology of Breast Cancer by Heide Schatten Pdf

Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics and the various impacts of designing new strategies as well as identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and anyone else interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer.

Author : Antonio Llombart Bosch,Vicente Felipo
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 48,7 Mb
Release : 2003
Category : Medical
ISBN : 0306477629

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New Trends in Cancer for the 21st Century by Antonio Llombart Bosch,Vicente Felipo Pdf

The latest advances in cancer research include basic research and its derived diagnostic, clinical and therapeutic applications. The book New Trends in Cancer for the 21st Century is written by individuals such as: molecular biologists whose tasks are, after sequencing the human genome, to decipher those new genes and pathways involved in the carcinogenesis process; clinical and molecular pathologists, who apply these discoveries for the molecular diagnosis and characterization of the tumour; and clinical oncologists, who treat patients. Pharmacogenetics introduces new perspectives in the translational fields with the design of drugs against specific targets, which are in clinical trials phases in 2003. Several organizations such as the EORTC (European Organization for Research and Treatment of Cancer) and the OECI (Organization of European Cancer Institutes) and comprehensive cancer centres play a crucial role in focusing cancer research on all these areas.

Author : Phuc Van Pham
Publisher : BoD – Books on Demand
Page : 570 pages
File Size : 53,7 Mb
Release : 2017-04-05
Category : Medical
ISBN : 9789535129998

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Breast Cancer by Phuc Van Pham Pdf

Breast Cancer - From Biology to Medicine thoroughly examines breast cancer from basic definitions, to cellular and molecular biology, to diagnosis and treatment. This book also has some additional focus on preclinical and clinical results in diagnosis and treatment of breast cancer. The book begins with introduction on epidemiology and pathophysiology of breast cancer in Section 1. In Section 2, the subsequent chapters introduce molecular and cellular biology of breast cancer with some particular signaling pathways, the gene expression, as well as the gene methylation and genomic imprinting, especially the existence of breast cancer stem cells. In Section 3, some new diagnostic methods and updated therapies from surgery, chemotherapy, hormone therapy, immunotherapy, radiotherapy, and some complementary therapies are discussed. This book provides a succinct yet comprehensive overview of breast cancer for advanced students, graduate students, and researchers as well as those working with breast cancer in a clinical setting.

Author : Anne M. Bowcock
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 40,6 Mb
Release : 1999-01-11
Category : Medical
ISBN : 9781592594566

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Breast Cancer by Anne M. Bowcock Pdf

A comprehensive state-of-the-art summary of breast cancer research and treatment by leading authorities. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis. In addition, the authors describe current and future methods of breast cancer treatment in depth, and discuss environment and diet as risk factors for the disease. Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics constitutes an excellent reference and resource for all those clinical and experimental oncologists, as well as genetic counselors nurses, who need to understand the latest developments in breast cancer biology, risk, and treatment.

Author : Dongfeng Tan,Henry T. Lynch
Publisher : Lippincott Williams & Wilkins
Page : 2177 pages
File Size : 47,9 Mb
Release : 2012-12-07
Category : Medical
ISBN : 9781469820644

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Principles of Molecular Diagnostics and Personalized Cancer Medicine by Dongfeng Tan,Henry T. Lynch Pdf

The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care.

Author : Martine J Piccart,Lawrence J Solin,Fatima Cardoso,William C Wood,Chie-Mien Hung
Publisher : Springer
Page : 1084 pages
File Size : 51,5 Mb
Release : 2016-05-01
Category : Electronic
ISBN : 3662517620

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Breast Cancer Management and Molecular Medicine by Martine J Piccart,Lawrence J Solin,Fatima Cardoso,William C Wood,Chie-Mien Hung Pdf

Bespoke treatment for individual cancers is no longer a dream and is now the primary goal for current research. This book provides an overview of the most recent techniques, agents and approaches for breast cancer and the tailoring of treatment.

Author : Liliana Streba,Dan Ionut Gheonea,Michael Schenker
Publisher : BoD – Books on Demand
Page : 158 pages
File Size : 55,8 Mb
Release : 2019-09-25
Category : Medical
ISBN : 9781838800055

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Current Trends in Cancer Management by Liliana Streba,Dan Ionut Gheonea,Michael Schenker Pdf

The field of cancer diagnosis, prognosis, and treatment is constantly advancing. From novel biomarkers to cutting-edge imaging solutions, changing chemotherapy protocols and novel immune-targeting agents, medical teams develop and test new ways to manage this ever-growing threat to the modern age. Imaging has been a reliable method for initial diagnosis and later surveillance of premalignant and cancerous lesions of the digestive tract. This book project aims to characterize the main diagnostic procedures and novel medical and surgical treatments, as well as provide an updated view on current guidelines, premalignant lesions management, and minimally invasive curative techniques.

Author : Marc E. Lippman,Robert Brent Dickson
Publisher : Unknown
Page : 0 pages
File Size : 41,7 Mb
Release : 1988
Category : Electronic
ISBN : LCCN:87038322

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Breast Cancer by Marc E. Lippman,Robert Brent Dickson Pdf

Author : Robert B. Dickson,Marc E. Lippman
Publisher : Springer
Page : 384 pages
File Size : 41,7 Mb
Release : 1994-07-31
Category : Health & Fitness
ISBN : UOM:39015032627203

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Mammary Tumorigenesis and Malignant Progression by Robert B. Dickson,Marc E. Lippman Pdf

The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth factors, hormones, tumor-host interactions, and determinants of metastases. Since our last volume, research in breast cancer has continued to proceed at an explosive rate. We hope the current volume will provide the reader with some of the excitement felt by the editors and authors as we begin to understand this all-too-common disease. The first section of this book is devoted to the basic processes of proli feration, differentiation, and malignant progression of breast cancer. T.l. Anderson and W.R. Miller lead off with a detailed description of controls on proliferation in the normal human breast and in breast cancer. This chapter strongly emphasizes pathological aspects. The second chapter, by M.R. Stampfer and P. Yaswen, presents a corresponding viewpoint through a presentation of experiments with human mammary epithelial cells in culture. The second section of the book emphasizes the genetic basis for breast cancer onset and malignant progression. Chapter 3, by M.-C. King and S.

Author : Sandra Lekin
Publisher : Unknown
Page : 0 pages
File Size : 48,7 Mb
Release : 2015-03-17
Category : Breast
ISBN : 1632410982

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Current Advances in Breast Cancer Research by Sandra Lekin Pdf

Scientists all over the world are researching the causes of breast cancer. In the past few years, it has become pretty apparent that breast cancer encompasses a number of molecularly separate tumors emerging from the epithelial cells of the breast. There

Author : Erwei Song,Hai Hu
Publisher : Springer
Page : 0 pages
File Size : 54,9 Mb
Release : 2018-01-30
Category : Medical
ISBN : 9811060193

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Translational Research in Breast Cancer by Erwei Song,Hai Hu Pdf

This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. In addition, major advances in cancer biology, immunology, genomics and metabolism have broken new ground for designing therapeutic approaches and selecting appropriate treatments on the basis of more precise information on the individual patient. As a result of these two trends, a clearer picture of the molecular landscape of breast cancers has facilitated the development of diagnostic, prognostic and predictive biomarkers for clinical oncology. All these aspects are addressed in this volume, which offers a comprehensive resource for researchers, graduate students and oncologists in cancer research.