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Author : Anthony R. Means
Publisher : Lippincott Williams & Wilkins
Page : 404 pages
File Size : 50,5 Mb
Release : 1995
Category : Science
ISBN : 078170233X
Calcium-dependent regulation of protein synthesis/regulation of calcium channels in the heart/intracellular calcium waves
Author : Wai Yiu Cheung
Publisher : Unknown
Page : 536 pages
File Size : 46,7 Mb
Release : 1980
Category : Medical
ISBN : UCSD:31822026060319
Author : J.J. Lemasters,C.R. Hackenbrock,R.G. Thurman,H.V. Westerhoff
Publisher : Springer Science & Business Media
Page : 647 pages
File Size : 47,9 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781489925510
In aerobic tissues such as heart, brain, kidney, liver and brown fat, mitochon dria account for more than 20% of cell protein and play an essential role in res piration, ATP formation, ketogenesis, gluconeogenesis, amino acid metabolism, ureagenesis, thermogenesis and a variety of other metabolic activities. The mecha nisms by which these activities are integrated and regulated within the overall context of cellular physiology is of much current research interest. In order to bring together scientists examining the various diverse aspects of this overall pro blem, an International Conference on INTEGRATION OF MITOCHONDRIAL FUNC TION was held June 4-7, 1987 at the Hanes Art Center on the campus of the Uni versity of North Carolina at Chapel Hill. The chapters of this volume derive from presentations made at this conference. The focus of INTEGRATION OF MITOCHONDRIAL FUNCTION is on signifi cant new experimental and theoretical advances concerning integration of mito chondrial function at the organelle, cell, tissue and whole organism levels of organization.
Author : Juliusz Ashot Kozak,James W. Putney, Jr.
Publisher : CRC Press
Page : 343 pages
File Size : 44,7 Mb
Release : 2017-07-14
Category : Science
ISBN : 9781498752732
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Author : Setsurō Ebashi
Publisher : Unknown
Page : 288 pages
File Size : 41,9 Mb
Release : 1984
Category : Biological control systems
ISBN : UCAL:B4494612
Regulation of cellular functions by calcium ions; Calcium channel and transmembrane control; Calcium dependent protease.
Author : Anonim
Publisher : Academic Press
Page : 307 pages
File Size : 52,6 Mb
Release : 2013-07-24
Category : Science
ISBN : 9780124079380
Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels Contributors are authoritative researchers who have produced important advances in the field The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
Page : 309 pages
File Size : 54,8 Mb
Release : 2011
Category : Science
ISBN : 9781615041237
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Author : Wai Yiu Cheung
Publisher : Academic Press
Page : 331 pages
File Size : 43,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483281988
Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonamides as calmodulin antagonists, phophorylase kinase, and phospholipidsensitive calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.
Author : Ernesto Carafoli,Claude B. Klee
Publisher : Oxford University Press, USA
Page : 664 pages
File Size : 47,6 Mb
Release : 1999
Category : Calcium
ISBN : 0195094212
Encompassing all aspects of calcium signalling, from methods of measuring calcium in cells to the molecular mechanisms for decoding its information, this comprehensive book balances historical aspects and state of the art developments.
Author : Oriol Bachs,Neus Agell
Publisher : Springer Science & Business Media
Page : 173 pages
File Size : 50,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783662216866
This book is about the role of calcium and calmodulin in the cell nucleus. Calcium, which is an important second messenger of signal transduction pathways, can also operate in the cell nucleus. Different calcium binding proteins, which are the targets of cellular calcium, have been identified in the nucleus of many different cell types. Prominent among these calcium binding proteins is calmodulin, which appears to be involved in the regulation of major nuclear functions such as gene expression and DNA replication.
Author : Ernesto Carafoli,Marisa Brini
Publisher : Springer Science & Business Media
Page : 591 pages
File Size : 55,8 Mb
Release : 2007-09-29
Category : Medical
ISBN : 9781402061912
Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : D. Marme
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 40,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642700705
The purpose of the present volume is to give a comprehensive and up-to-date 2 survey of the nature and role of calcium ions (Ca +) in the regulation of cel 2 lular function. Since Ca + has gained in interest over the past years as a cel lular messenger in signal transduction, and since the discovery of its cellular receptor protein, calmodulin, has helped in understanding its mode of action in molecular terms, we felt that an interdisciplinary selection of topics from the calcium field could provide a good source of information for all those in terested in calcium-mediated physiology. The volume begins with an overview on the synarchic nature of the two 2 cellular messengers, cyclic AMP and Ca +. The next three chapters deal with 2 the various transport mechanisms for Ca +. The biochemistry and molecular biology of calmodulin, as well as the cellular localization of calmodulin and calmodulin-binding proteins, are reviewed. Calcium regulation of smooth muscle contraction introduces the pharmacology of calcium antagonists.
Author : Wai Yiu Cheung
Publisher : Academic Press
Page : 527 pages
File Size : 53,8 Mb
Release : 2013-09-03
Category : Medical
ISBN : 9781483217482
Calcium and Cell Function, Volume III covers the many aspects of research on calcium, dealing with its biochemistry, biology, and pharmacology in animals as well as in plants. The book discusses a novel cellular signaling system based on the integration of phospholipid and calcium metabolism; the transport of calcium by sarcoplasmic reticulum; and the energetics and chemistry for interactions between calmodulin and calmodulin-binding proteins. The text also describes the specificity of trifluoperazine and related phenothiazines for calcium-binding proteins; the structure, function, and regulation of phosphorylase kinase; and the regulation of glycogen synthase by multiple protein kinases. The role of calmodulin in synaptic function and neurosecretion; the stimulation of the synthesis of neurotransmitters by calmodulin-dependent phosphorylation; as well as the role of calcium in axoplasmic transport in nerve are also considered. The book further tackles calcium control of the intestinal microvillus cytoskeleton; the possible role of calmodulin in the regulation of insulin release and protein phosphorylation by calcium and cyclic AMP; and the role of calcium in mediating cellular functions important for growth and development in higher plants. The text also looks into the localization of calmodulin in tissue culture cells; and the characterization and regulation of calcium-dependent neutral protease. Zoologists, cell biologists, biochemists, and pharmacologists will find the book invaluable.
Author : Ronald P. Rubin
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468442175
Since the publication of my previous monograph in 1974, important progress has been made in the broad area of calcium research, partic ularly as it pertains to secretory phenomena. The significant advance in methodology, while widening the scope of our knowledge, has caused research in this particular area to become more and more specialized. It has, therefore, become increasingly difficult for researchers to consider and evaluate work outside their own areas of specialization and to com prehend the field from a broad perspective. While many valuable re views on the importance of calcium in cellular function are being pro duced, they have not attempted to pull together all of the existing knowledge into a more general narrative. This volume brings together experimental data and theories from diverse sources, and attempts to synthesize into a broad conceptual framework the massive amount of specialized information that presently exists in the general area of cal cium metabolism and the secretory process. It is impossible in a book of this length to discuss specific references in detail and still maintain readability, so generalizations must be made.