Calmodulin Antagonists And Cellular Physiology

Author : Hiroyoshi Hidaka
Publisher : Elsevier
Page : 569 pages
File Size : 49,5 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323145732

Get Book

Calmodulin Antagonists and Cellular Physiology by Hiroyoshi Hidaka Pdf

Calmodulin Antagonists and Cellular Physiology focuses on the biochemistry of calmodulin antagonists as regulators of cellular physiology. Emphasis is placed on the use of calmodulin antagonists as an indicator of calmodulin function. The mechanism of action of calmodulin antagonists and their interactions with calmodulin are explored. This book is comprised of 33 chapters and begins with an introduction to the biochemical aspects of calmodulin as well as its distribution and functions, followed by a discussion on how calmodulin antagonists and other agents modulate Ca2+-dependent regulatory systems. The next section is devoted to the mechanism of action of calmodulin antagonists and includes chapters that examine the interaction of various drugs with calmodulin and the structure-activity relationships of calmodulin antagonists. The effects of calmodulin antagonists on cell proliferation and growth are then discussed. The remaining chapters deal with the role of calmodulin antagonists in cell function and the contractile process, along with their effect on protein kinase C. This monograph will be a useful resource for biochemists as well as students and researchers in biochemistry.

Author : D. Marme
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642700705

Get Book

Calcium and Cell Physiology by D. Marme Pdf

The purpose of the present volume is to give a comprehensive and up-to-date 2 survey of the nature and role of calcium ions (Ca +) in the regulation of cel 2 lular function. Since Ca + has gained in interest over the past years as a cel lular messenger in signal transduction, and since the discovery of its cellular receptor protein, calmodulin, has helped in understanding its mode of action in molecular terms, we felt that an interdisciplinary selection of topics from the calcium field could provide a good source of information for all those in terested in calcium-mediated physiology. The volume begins with an overview on the synarchic nature of the two 2 cellular messengers, cyclic AMP and Ca +. The next three chapters deal with 2 the various transport mechanisms for Ca +. The biochemistry and molecular biology of calmodulin, as well as the cellular localization of calmodulin and calmodulin-binding proteins, are reviewed. Calcium regulation of smooth muscle contraction introduces the pharmacology of calcium antagonists.

Author : Wai Yiu Cheung
Publisher : Academic Press
Page : 331 pages
File Size : 54,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483281988

Get Book

Calcium and Cell Function by Wai Yiu Cheung Pdf

Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonamides as calmodulin antagonists, phophorylase kinase, and phospholipidsensitive calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.

Author : Wai Yiu Cheung
Publisher : Unknown
Page : 128 pages
File Size : 52,9 Mb
Release : 1980
Category : Calcium
ISBN : LCCN:80000985

Get Book

Calcium and Cell Function: Calmodulin by Wai Yiu Cheung Pdf

Author : Peter Agre
Publisher : CRC Press
Page : 768 pages
File Size : 45,8 Mb
Release : 1989-03-24
Category : Science
ISBN : 0824780221

Get Book

Red Blood Cell Membranes by Peter Agre Pdf

This book is devoted to the red blood cell membrane, its structure and function, and abnormalities in disease states. It presents a well-documented and well-illustrated comprehensive picture of clinical manifestations of red blood cell disorders.

Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1068 pages
File Size : 54,7 Mb
Release : 1988
Category : Medicine
ISBN : MINN:31951000310404Q

Get Book

National Library of Medicine Current Catalog by National Library of Medicine (U.S.) Pdf

Author : Peter F. Baker
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642718069

Get Book

Calcium in Drug Actions by Peter F. Baker Pdf

The Editorial Board and the Publishers of the Handbook of Experimental Pharmacology wish to express their profound grief at the untimely death of Professor Peter Baker. Aware of his international recognition as an expert on the ubiquitous role of calcium in physiological processes and their pharma cological control, the Board was gratified when Professor Baker accepted its invitation to edit a new Handbook volume on "Calcium in Drug Actions". He went about this task with his usual energy and effectiveness so that, in the few months before his unexpected death, Professor Baker had mustered his distinguished contributors, got them to provide their manuscripts, and seen almost the entire material into the press. This achievement is all the more remarkable when one bears in mind the extraordinary number of his other commitments during the same time; they are mentioned in Sir Alan Hodgkin's preface to this volume. With so many other professional and personal responsibilities upon him, the Board of the Handbook wishes to record its grateful appreciation for the admirable way in which Professor Baker took on and carried out the additional work of bringing this fine book into existence; and the Board wishes it to be dedicated to the memory of Professor Peter Frederick Baker. The Editorial Board: G. V. R. BORN, P. CUATRECASAS, H. HERKEN, A.

Author : B. U. Raess,G. Tunnicliff
Publisher : Springer Science & Business Media
Page : 479 pages
File Size : 48,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461245001

Get Book

The Red Cell Membrane by B. U. Raess,G. Tunnicliff Pdf

"After being frequently urged to write upon this subject, and as often declining to do it, from apprehension of my own inability, I am at length compelled to take up the pen, however unqualified I may still feel myself for the task. " William Withering, M. D. ' I have yet to find a description or a quote that better summanzes my initial ambivalence towards embarking on such an endeavor as partici pating in putting together this monograph. The impetus for The Red-Cell has been a simple, genuine Membrane: A Model for Solute Transport desire to bring together an authoritative account of the' 'state of the art and knowledge" in the red-ceIl-membrane transport field. In particular, it seems important to emphasize the pivotal role the red cell has played for several decades in the discovery and the elucidation of mechanisms of plasma-membrane transport processes. It is only with such knowledge that we can hope to push ahead and make progress in this exciting, multifaceted area. Eventually, one hopes to not only further our knowledge of red cells, but apply the newly gained insights to any other of the plasma membrane. cell with the common denominator In this compendium of reviews, the reader will find that the term model will take on a variety of gists and meanings. In some chapters, the red cell has been chosen as a model membrane solely on the basis of its preeminent design and simplicity.

Author : Laszlo Szekeres,Julius G. Papp
Publisher : Springer Science & Business Media
Page : 739 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642789205

Get Book

Pharmacology of Smooth Muscle by Laszlo Szekeres,Julius G. Papp Pdf

A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on different organ systems containing smooth muscle - with the exception of the vascular system which, owing to the great amount of new knowledge accumulated in this area in recent years, is treated in a special chapter. In this connection the effect of antihypertensive agents and drugs affecting the coronary and cerebrovascular smooth muscle is also covered. For all those wishing to gain a deeper insight into smooth muscle pharmacology.

Author : Anonim
Publisher : Academic Press
Page : 881 pages
File Size : 40,9 Mb
Release : 2014-06-28
Category : Science
ISBN : 9780080918822

Get Book

Cytology and Cell Physiology, Supplement 17 by Anonim Pdf

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Author : Geoffrey H. Bourne
Publisher : Elsevier
Page : 884 pages
File Size : 40,8 Mb
Release : 1987-11-28
Category : Science
ISBN : 0123643783

Get Book

Cytology and Cell Physiology, Supplement 17 by Geoffrey H. Bourne Pdf

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Author : Hideya Saitō,Masaru Minami
Publisher : VSP
Page : 392 pages
File Size : 47,9 Mb
Release : 1992
Category : Medical
ISBN : 9067641405

Get Book

Antihypertensive Drugs Today by Hideya Saitō,Masaru Minami Pdf

Author : Robert H. Cox
Publisher : Springer Science & Business Media
Page : 245 pages
File Size : 49,9 Mb
Release : 2013-03-08
Category : Medical
ISBN : 9781468460155

Get Book

Cellular and Molecular Mechanisms in Hypertension by Robert H. Cox Pdf

Hypertension is recognized to be one of the major risk factors for the development of peripheral vascular disease. The last decade has witnessed several major advances in therapy for hypertension, including the development of angiotensin-converting enzyme inhibitors and calcium channel blockers. These compounds have greatly improved the ability to control blood pressure and to reduce the impact of this risk factor on morbidity and mortality. In spite of these advances, cardiovascular disease remains a major health problem in most modern industrialized countries with related deaths exceeding those from all other causes combined. In contrast to these advances in therapy, our understanding of the basic mechanisms responsible for the pathogenesis of hypertension remains incomplete. Recent studies have produced new insights into the nature of the regulation of muscle contraction in both heart and blood vessels as well as the changes in muscle function that occur in hypertension. However, the effects of antihypertensive therapy, both in terms of restoring normal function and in producing reversal of hypertension-associated changes, has not been as thoroughly studied, especially in the vasculature. Studies in the heart suggest that the efficacy of different therapeutic agents in restoring normal function and reversing hypertensive changes vary substantially with the mechanism of action of the therapeutic agent. It has also been recently determined that some therapeutic agents produce adverse effects on plasma lipid profiles, which could lead to the secondary acceleration of the atherosclerotic process, while at the same time normalizing blood pressure.

Author : John W. Holaday,Ping-Yee Law,Albert Herz
Publisher : Unknown
Page : 754 pages
File Size : 43,9 Mb
Release : 1986
Category : Endorphins
ISBN : PURD:32754081426334

Get Book

Progress in Opioid Research by John W. Holaday,Ping-Yee Law,Albert Herz Pdf

Author : Anonim
Publisher : Unknown
Page : 774 pages
File Size : 44,7 Mb
Release : 1976
Category : Drug abuse
ISBN : UOM:39015012384262

Get Book

NIDA Research Monograph by Anonim Pdf