Cancer Genetics A Clinical Approach

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Cancer Genetics: A Clinical Approach

Xavier Llor,Erin Wysong Hofstatter
Cancer Genetics A Clinical Approach Book PDF

Author : Xavier Llor,Erin Wysong Hofstatter
Publisher : McGraw Hill Professional
Page : 474 pages
File Size : 44,9 Mb
Release : 2021-11-19
Category : Medical
ISBN : 9781260440287

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Cancer Genetics: A Clinical Approach by Xavier Llor,Erin Wysong Hofstatter Pdf

The ultimate guide to caring for and communicating with patients suffering with hereditary cancer syndromes Providing the essential tools needed to understand clinical cancer genetics, Cancer Genetics: A Clinical Approach builds your mastery of differential diagnosis formulation, all the available genetic testing options at your disposal, interpreting results logically and accurately, and educating patients and their families about effective cancer prevention methods. This unparalleled resource walks you through the process of effectively and thoughtfully counseling patients—from pre-test counseling and relaying test results to navigating the legal implications of hereditary conditions and coping with the resulting psychological challenges. Cancer Genetics: A Clinical Approach is ideal for both specialized cancer genetics clinics or any healthcare professional seeking to improve their skills in identifying patients with possible hereditary cancer syndromes and recognizing which ones should be referred to a high-risk/clinical genetics specialty program.

Principles of Clinical Cancer Genetics

Daniel C. Chung,Daniel A. Haber
Principles of Clinical Cancer Genetics Book PDF

Author : Daniel C. Chung,Daniel A. Haber
Publisher : Springer Science & Business Media
Page : 234 pages
File Size : 41,7 Mb
Release : 2010-07-20
Category : Medical
ISBN : 9780387938462

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Principles of Clinical Cancer Genetics by Daniel C. Chung,Daniel A. Haber Pdf

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Pediatric Cancer Genetics

Nathaniel H. Robin,Meagan Farmer
Pediatric Cancer Genetics Book PDF

Author : Nathaniel H. Robin,Meagan Farmer
Publisher : Elsevier Health Sciences
Page : 350 pages
File Size : 52,9 Mb
Release : 2017-08-22
Category : Medical
ISBN : 9780323495967

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Pediatric Cancer Genetics by Nathaniel H. Robin,Meagan Farmer Pdf

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Medical Genetics

Lynn B. Jorde, PhD,John C. Carey, MD, MPH,Michael J. Bamshad, MD
Medical Genetics Book PDF

Author : Lynn B. Jorde, PhD,John C. Carey, MD, MPH,Michael J. Bamshad, MD
Publisher : Elsevier Health Sciences
Page : 371 pages
File Size : 55,7 Mb
Release : 2015-09-04
Category : Electronic
ISBN : 9780323188357

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Medical Genetics by Lynn B. Jorde, PhD,John C. Carey, MD, MPH,Michael J. Bamshad, MD Pdf

Popular for its highly visual, clinical approach, Medical Genetics delivers an accessible yet thorough understanding of this active and fast-changing field. Key updates in this new edition cover the latest developments which are integrated with clinical practice to emphasize the central principles and how they apply to practice. Photographs, illustrations, and tables, along with boxes containing patient/family vignettes demonstrate clinical relevance and enhance visual impact of the material for easier and more effective learning and retention. Includes access to the complete text and images online at studentconsult.com along with 200 additional USMLE-style questions for self-assessment. Mini-summaries, study questions, suggested reading, and a detailed glossary supplement and reinforce what you learn from the text. More than 230 photographs, illustrations, and tables, along with patient/family vignettes clarify difficult concepts and demonstrate clinical significance. Clinical Commentary Boxes help demonstrate how the hard science of genetics has real applications to everyday patient problems and prepare you for problem-based integrated courses. The latest knowledge and research on gene identification, cancer genetics, gene testing and gene therapy, common disorders, ethical and social issues, and much more so you can keep up with current developments in genetics. Student Consult eBook version included with purchase. This enhanced eBook experience allows access to 200 additional USMLE questions, as well as new materials (outlined above) designed to produce a more rounded learning experience.

A Guide to Cancer Genetics in Clinical Practice

Sue Clark,
A Guide to Cancer Genetics in Clinical Practice Book PDF

Author : Sue Clark,
Publisher : tfm Publishing Limited
Page : 246 pages
File Size : 47,7 Mb
Release : 2009-05-01
Category : Medical
ISBN : 9781908986351

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A Guide to Cancer Genetics in Clinical Practice by Sue Clark, Pdf

FIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions.

Oncogenomics

Charles Brenner,David Duggan
Oncogenomics Book PDF

Author : Charles Brenner,David Duggan
Publisher : John Wiley & Sons
Page : 411 pages
File Size : 44,8 Mb
Release : 2004-11-19
Category : Medical
ISBN : 9780471476641

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Oncogenomics by Charles Brenner,David Duggan Pdf

This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.

Clinical Cancer Genetics

Kenneth Offit
Clinical Cancer Genetics Book PDF

Author : Kenneth Offit
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 50,8 Mb
Release : 2030-05-07
Category : Medical
ISBN : 0471458937

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Clinical Cancer Genetics by Kenneth Offit Pdf

Written by a world-recognized leader in this emerging field, Clinical Cancer Genetics provides an updated and expanded treatment of Kenneth Offit's seminal text on the clinical management associated with syndromes of cancer predisposition, with a thorough review of the relevant molecular genetics. This second edition features new coverage of pharmacogenetics, gene therapy trials, high throughput genotyping, and microarrays and includes a new focus on epigenetic events in carcinogenesis within background chapter on cancer genetics. Expanded coverage highlights more uncommon and rare cancer predisposition syndromes.

Cancer Genetics for the Clinician

Gail L. Shaw
Cancer Genetics for the Clinician Book PDF

Author : Gail L. Shaw
Publisher : Springer Science & Business Media
Page : 224 pages
File Size : 42,9 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015048510765

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Cancer Genetics for the Clinician by Gail L. Shaw Pdf

Cancer genetics is a quickly growing field within oncology. The ability to identify individuals at high risk for cancer improves the chance of early prevention and detection of cancer. The results of genetic testing affect quality of life, employment, and ability to be insured. This volume will provide an overview of cancer genetics, inherited cancer susceptibility, and available services and testing, including both the risks and benefits of testing. Some of the topics covered include: genetics of breast and ovarian cancer, testing minors for inherited cancer risk, chemoprevention of heritable cancer risk, genetics of colorectal cancer, insurance issues in genetic testing for cancer, ethical and legal issues in genetic testing for cancer susceptibility, testing for breast cancer risk in the Ashkenazim, estimating individualized risk of breast cancer, genetic counseling for the individual with inherited cancer susceptibility, and components of a genetic cancer risk clinic. While heritable cancers account for between five and ten percent of all cancer cases, molecular alterations attributable to specific inherited cancer susceptibility may give us important clues into the mechanism by which cancer occurs, not only in predisposed individuals, but also for sporadic cases.

Genetics in Practice

Jo Haydon
Genetics in Practice Book PDF

Author : Jo Haydon
Publisher : John Wiley & Sons
Page : 290 pages
File Size : 46,8 Mb
Release : 2007-10-22
Category : Medical
ISBN : 9780470725252

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Genetics in Practice by Jo Haydon Pdf

Nurses are increasingly being asked to provide information when a genetic diagnosis is made, whether to the individual patient or to members of his or her family. This book provides a comprehensive introduction to present day genetic services, to help professionals feel more confident when dealing with queries or advising where to go for further information. Comprehensive case studies are used to explain the various models of inheritance and explore the possibilities for families, following genetic diagnosis. Family history-taking, risk assessment, basic biology of chromosomes and genes, and laboratory techniques are all described. Issues of ethnicity and ethics are addressed. The book also discusses the development of the role of the genetic nurse counselor.

Genetics for Health Professionals in Cancer Care

Chris Jacobs,Lorraine Robinson,Patricia Webb
Genetics for Health Professionals in Cancer Care Book PDF

Author : Chris Jacobs,Lorraine Robinson,Patricia Webb
Publisher : Oxford University Press, USA
Page : 363 pages
File Size : 48,7 Mb
Release : 2014
Category : Medical
ISBN : 9780199672844

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Genetics for Health Professionals in Cancer Care by Chris Jacobs,Lorraine Robinson,Patricia Webb Pdf

This title equips health professionals with the knowledge and skills required for all aspects of managing cancer family history, discussing the challenges raised and providing practical guidance on setting up a cancer family history clinic in primary and secondary care.

The Genetics of Cancer

B.A. Ponder,M.J. Waring
The Genetics of Cancer Book PDF

Author : B.A. Ponder,M.J. Waring
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401106771

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The Genetics of Cancer by B.A. Ponder,M.J. Waring Pdf

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Medical Genetics

Lynn B. Jorde
Medical Genetics Book PDF

Author : Lynn B. Jorde
Publisher : Unknown
Page : 392 pages
File Size : 52,8 Mb
Release : 2006
Category : Genetic disorders
ISBN : UOM:39015063152527

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Medical Genetics by Lynn B. Jorde Pdf

'Medical Genetics' offers up-to-date information on modern genetics. This comprehensive study includes the latest findings from genetic research and how that knowledge can be used in clinical practice.

Cancer Genomics for the Clinician

Ramaswamy Govindan, MD,Ashiq Masood, MD
Cancer Genomics for the Clinician Book PDF

Author : Ramaswamy Govindan, MD,Ashiq Masood, MD
Publisher : Springer Publishing Company
Page : 184 pages
File Size : 44,7 Mb
Release : 2019-01-28
Category : Medical
ISBN : 9780826168689

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Cancer Genomics for the Clinician by Ramaswamy Govindan, MD,Ashiq Masood, MD Pdf

Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more. Assembled in an accessible format specifically designed for the non-expert, this book provides the clinical oncologist, early career practitioner, and trainee with an essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. With this resource, physicians and trainees will increase their breadth of knowledge and be better equipped to educate patients and families who want to know more about their genetic predispositions to cancer and the targeted therapies that could be considered and prescribed. Key Features: Describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer types Explains what mutations are, what tests are needed, and how to interpret the results Provides information on FDA-approved targeted therapies that are being used in the clinic Covers different sequencing platforms and technologies and how they perform in research settings Includes access to the fully searchable eBook

Genetics of Melanoma

Carlos A. Torres-Cabala,Jonathan L. Curry
Genetics of Melanoma Book PDF

Author : Carlos A. Torres-Cabala,Jonathan L. Curry
Publisher : Springer
Page : 288 pages
File Size : 44,9 Mb
Release : 2016-05-11
Category : Medical
ISBN : 9781493935543

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Genetics of Melanoma by Carlos A. Torres-Cabala,Jonathan L. Curry Pdf

This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.

Cancer Principles and Practice of Oncology

Ellen Matloff
Cancer Principles and Practice of Oncology Book PDF

Author : Ellen Matloff
Publisher : Unknown
Page : 240 pages
File Size : 40,6 Mb
Release : 2015-04-24
Category : Electronic books
ISBN : 1469874792

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Cancer Principles and Practice of Oncology by Ellen Matloff Pdf

Genetic testing and counseling for cancer have made great strides in recent years. The popular demand for advanced screening, advances in testing, and the response of insurance companies and corporations have all served to shape this important area of cancer risk management. This practical, user-friendly guidebook allows you to search by disease site for the hereditary cancer syndromes relevant to your patient's cancer. This handy resource will help you formulate questions when expanding that patient's personal and family history, identify the genes that are most relevant, determine whether to.