Cancer Related Genetic Testing And Counseling

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Cancer-Related Genetic Testing and Counseling

Institute of Medicine,National Cancer Policy Forum
Cancer Related Genetic Testing and Counseling Book PDF

Author : Institute of Medicine,National Cancer Policy Forum
Publisher : National Academies Press
Page : 134 pages
File Size : 46,8 Mb
Release : 2007-09-22
Category : Medical
ISBN : 9780309109970

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Cancer-Related Genetic Testing and Counseling by Institute of Medicine,National Cancer Policy Forum Pdf

These proceedings of a workshop presented to the Institute of Medicine's (IOM) National Cancer Policy Forum on March 30, 2007, are the result of forum discussions about genetic testing and counseling at its meetings on June 16 and October 30, 2006. Those discussions, led by forum members Betty Ferrell and Patricia Ganz, noted that genetic testing and counseling are becoming more complex and important for informing patients and families of risks and benefits of certain courses of action, and yet organized expert programs are in short supply. The subject matter involves not only the scientific and clinical aspects but also workforce and reimbursement issues, among others. Drs. Ferrell and Ganz proposed that the forum could provide a useful review of the various important implications of these issues by holding and reporting a workshop on the subject. They volunteered to work with staff to organize and lead such a workshop. The agenda for the workshop is reproduced in the appendix to these proceedings. It includes the presentations of the invited speakers and the comments of speakers, forum members, and others in attendance as transcribed and edited to eliminate redundancies, grammatical errors, and otherwise make them more readable. Cancer-Related Genetic Testing and Counseling : Workshop Proceedings summarizes the workshop.

Counseling About Cancer

Katherine A. Schneider,Anu Chittenden,Kristen Mahoney Shannon
Counseling About Cancer Book PDF

Author : Katherine A. Schneider,Anu Chittenden,Kristen Mahoney Shannon
Publisher : John Wiley & Sons
Page : 548 pages
File Size : 48,6 Mb
Release : 2023-05-15
Category : Medical
ISBN : 9781119466468

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Counseling About Cancer by Katherine A. Schneider,Anu Chittenden,Kristen Mahoney Shannon Pdf

Counseling About Cancer A key resource for all genetic counselors and other healthcare providers, this comprehensive reference has been completely updated and reorganized for its fourth edition Over 50 hereditary cancer predisposition genes have now been identified. Genetic testing can be a powerful tool in assessing individual cancer risk and creating robust medical plans, but can also be a complex process, with personal and familial factors carrying real emotional weight. As such, genetic counseling for patients and their families during the process of genetic testing is critical. Counseling about Cancer: Strategies for Genetic Counseling is the only comprehensive resource available for clinicians who want to understand and apply these dimensions of patient care. This updated and reorganized edition provides detailed information designed to be incorporated in a variety of clinical and health-care contexts. Updated with the latest guidance and research, it promises to continue as the indispensable guide to this challenging subject. Readers of the fourth edition of Counseling about Cancer will also find: New chapters analyzing pediatric cancer syndromes, genetic testing technology, and more Increased focus on gynecological cancer syndromes and related genes Detailed case studies to reinforce themes of each chapter Counseling about Cancer is a useful reference for genetic counselors and other healthcare providers looking to familiarize themselves with best practices of patient counseling and care.

Counseling About Cancer

Katherine A. Schneider
Counseling About Cancer Book PDF

Author : Katherine A. Schneider
Publisher : John Wiley & Sons
Page : 498 pages
File Size : 44,5 Mb
Release : 2011-10-26
Category : Medical
ISBN : 9781118119914

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Counseling About Cancer by Katherine A. Schneider Pdf

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

The Genetics of Cancer

B.A. Ponder,M.J. Waring
The Genetics of Cancer Book PDF

Author : B.A. Ponder,M.J. Waring
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401106771

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The Genetics of Cancer by B.A. Ponder,M.J. Waring Pdf

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Pediatric Cancer Genetics

Nathaniel H. Robin,Meagan Farmer
Pediatric Cancer Genetics Book PDF

Author : Nathaniel H. Robin,Meagan Farmer
Publisher : Elsevier Health Sciences
Page : 350 pages
File Size : 44,9 Mb
Release : 2017-08-22
Category : Medical
ISBN : 9780323495967

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Pediatric Cancer Genetics by Nathaniel H. Robin,Meagan Farmer Pdf

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Counseling About Cancer

Katherine A. Schneider
Counseling About Cancer Book PDF

Author : Katherine A. Schneider
Publisher : John Wiley & Sons
Page : 498 pages
File Size : 52,7 Mb
Release : 2011-12-08
Category : Medical
ISBN : 9780470081501

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Counseling About Cancer by Katherine A. Schneider Pdf

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

Clinical Hematology and Oncology

Bruce Furie
Clinical Hematology and Oncology Book PDF

Author : Bruce Furie
Publisher : Unknown
Page : 1300 pages
File Size : 51,5 Mb
Release : 2003
Category : Medical
ISBN : 044306556X

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Clinical Hematology and Oncology by Bruce Furie Pdf

The chapters in the first section focus on individual presenting symtoms and/or findings and describe the best approach to sort through the differential diagnosis, determine whether the problem is hematologic or oncologic, and to rapidly ascertain the definitive diagnosis. The chapters in the second section each describe a specific disease with a focus on evaluation and management.

Cancer Principles and Practice of Oncology: Handbook of Clinical Cancer Genetics

Ellen Matloff
Cancer Principles and Practice of Oncology Handbook of Clinical Cancer Genetics Book PDF

Author : Ellen Matloff
Publisher : Lippincott Williams & Wilkins
Page : 208 pages
File Size : 46,6 Mb
Release : 2013-03-25
Category : Medical
ISBN : 9781469833880

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Cancer Principles and Practice of Oncology: Handbook of Clinical Cancer Genetics by Ellen Matloff Pdf

This practical, user-friendly guidebook will allow the clinician to search under disease site for the hereditary cancer syndromes relevant for his/her patient's cancer. For example, a gynecologist oncologist whose patient has ovarian cancer can turn to the Ovary chapter and quickly read a summary of all of the hereditary cancer syndromes that include ovarian cancer. She can learn the questions she should be asking when expanding that patient's personal and family history, which genes are most relevant, whether to refer that patient on for genetic counseling and testing, and how to manage that patient long-term if the patient is mutation positive or negative. The same holds true for the practicing oncologist, surgeon, urologist, endocrinologist, gynecologist, primary care physician, physician's assistant, advanced practice nurse and any other clinician seeing a patient who has had cancer. This guidebook also contains an overview article on genetic counseling and testing and several in depth articles on issues that are up and coming in the field of hereditary cancer.

Genetic Counseling in Breast Cancer

Beth N. Peshkin
Genetic Counseling in Breast Cancer Book PDF

Author : Beth N. Peshkin
Publisher : IOS Press
Page : 160 pages
File Size : 45,7 Mb
Release : 2007
Category : Breast
ISBN : 1586037935

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Genetic Counseling in Breast Cancer by Beth N. Peshkin Pdf

A testament to how far the field of genetic counseling for breast cancer susceptibility has advanced since the mid-1990s, following the cloning of two major breast (and ovarian) cancer susceptibility genes, BRCA1 and BRCA2.

Clinical Cancer Genetics

Kenneth Offit
Clinical Cancer Genetics Book PDF

Author : Kenneth Offit
Publisher : Wiley-Blackwell
Page : 452 pages
File Size : 42,6 Mb
Release : 2030-05-07
Category : Medical
ISBN : 0471458937

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Clinical Cancer Genetics by Kenneth Offit Pdf

Written by a world-recognized leader in this emerging field, Clinical Cancer Genetics provides an updated and expanded treatment of Kenneth Offit's seminal text on the clinical management associated with syndromes of cancer predisposition, with a thorough review of the relevant molecular genetics. This second edition features new coverage of pharmacogenetics, gene therapy trials, high throughput genotyping, and microarrays and includes a new focus on epigenetic events in carcinogenesis within background chapter on cancer genetics. Expanded coverage highlights more uncommon and rare cancer predisposition syndromes.

Diagnosis and Management of Hereditary Cancer

John W. Henson,Robert G Resta
Diagnosis and Management of Hereditary Cancer Book PDF

Author : John W. Henson,Robert G Resta
Publisher : Academic Press
Page : 386 pages
File Size : 51,9 Mb
Release : 2021-03-20
Category : Science
ISBN : 9780323885829

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Diagnosis and Management of Hereditary Cancer by John W. Henson,Robert G Resta Pdf

Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families. Unique table-based presentation of 50 key aspects of hereditary cancer Clinical features, genetics, genetic testing, diagnosis, counseling, and management of multiple hereditary cancer syndromes Table-based format to inter-relate clinical and scientific information Landscape layout for easier viewing of tabular information

Genetics for Health Professionals in Cancer Care

Chris Jacobs,Lorraine Robinson,Patricia Webb
Genetics for Health Professionals in Cancer Care Book PDF

Author : Chris Jacobs,Lorraine Robinson,Patricia Webb
Publisher : OUP Oxford
Page : 384 pages
File Size : 47,8 Mb
Release : 2014-08-14
Category : Medical
ISBN : 9780191653490

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Genetics for Health Professionals in Cancer Care by Chris Jacobs,Lorraine Robinson,Patricia Webb Pdf

The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer. Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care. Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.

Understanding Genomic and Hereditary Cancer Risk

Suzanne M. Mahon
Understanding Genomic and Hereditary Cancer Risk Book PDF

Author : Suzanne M. Mahon
Publisher : Unknown
Page : 0 pages
File Size : 53,6 Mb
Release : 2021
Category : Cancer
ISBN : 1635930499

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Understanding Genomic and Hereditary Cancer Risk by Suzanne M. Mahon Pdf

"Collecting a family medical history is a regular component of the nursing assessment process that often includes information on familial cancer diagnoses, and patients may fear that they or their loved ones might be at increased risk for developing cancer because of hereditary factors. Although true inherited risk for developing cancer is much less common than acquired risk for developing cancer, approximately 10% of cancer diagnoses can be attributed to inherited risk. The identification of families exhibiting hereditary cancer syndromes enables individuals at risk to engage in increased surveillance and, in some cases, risk-reducing surgery and other preventive measures, which ultimately lead to decreasing the morbidity and mortality associated with a cancer diagnosis. The role of the nurse in helping patients to understand and manage hereditary cancer risk requires specialized knowledge of genetics and genomics concepts. Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses provides background on basic genetic and genomic concepts, particularly those related to hereditary risk for developing cancer, to aid nurses in knowing when and why to refer patients. It also provides reliable information about how and why genetic and genomic testing can both aid in treatment decisions and also guide recommendations for cancer prevention and early detection. The nurse's role in genetic testing and counseling are discussed, as are questions and answers about types of testing, including direct-to-consumer genetic testing. Following genetic testing, most genetics professionals provide detailed information about recommendations for care, including recommendations for ongoing prevention and early detection. For patients who are found to have a harmful mutation, these recommendations can be extensive and are based on the personal and family medical history, as well as the specific variant. This book provides quick overviews of many of the more common hereditary variants as well as resources for more information. This handbook provides nurses with the essentials to understand genomic and hereditary cancer risk, to assist in facilitating interprofessional care with genetics and other oncology professionals, and to provide their patients with accurate and reassuring information"--

Hereditary Breast and Ovarian Cancer

Seigo Nakamura,Daisuke Aoki,Yoshio Miki
Hereditary Breast and Ovarian Cancer Book PDF

Author : Seigo Nakamura,Daisuke Aoki,Yoshio Miki
Publisher : Springer Nature
Page : 324 pages
File Size : 51,7 Mb
Release : 2021-10-20
Category : Medical
ISBN : 9789811645211

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Hereditary Breast and Ovarian Cancer by Seigo Nakamura,Daisuke Aoki,Yoshio Miki Pdf

This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.

Principles of Clinical Cancer Genetics

Daniel C. Chung,Daniel A. Haber
Principles of Clinical Cancer Genetics Book PDF

Author : Daniel C. Chung,Daniel A. Haber
Publisher : Springer Science & Business Media
Page : 234 pages
File Size : 55,8 Mb
Release : 2010-07-20
Category : Medical
ISBN : 9780387938462

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Principles of Clinical Cancer Genetics by Daniel C. Chung,Daniel A. Haber Pdf

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.