Diagnosis And Management Of Hereditary Cancer

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Diagnosis and Management of Hereditary Cancer

Author : John W. Henson,Robert G Resta
Publisher : Academic Press
Page : 386 pages
File Size : 47,8 Mb
Release : 2021-03-20
Category : Science
ISBN : 9780323885829

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Diagnosis and Management of Hereditary Cancer by John W. Henson,Robert G Resta Pdf

Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families. Unique table-based presentation of 50 key aspects of hereditary cancer Clinical features, genetics, genetic testing, diagnosis, counseling, and management of multiple hereditary cancer syndromes Table-based format to inter-relate clinical and scientific information Landscape layout for easier viewing of tabular information

Rare Hereditary Cancers

Author : Gabriella Pichert,Chris Jacobs
Publisher : Springer
Page : 248 pages
File Size : 48,6 Mb
Release : 2016-04-13
Category : Medical
ISBN : 9783319299983

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Rare Hereditary Cancers by Gabriella Pichert,Chris Jacobs Pdf

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.

Counseling About Cancer

Author : Katherine A. Schneider
Publisher : John Wiley & Sons
Page : 498 pages
File Size : 46,6 Mb
Release : 2011-10-26
Category : Medical
ISBN : 9781118119914

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Counseling About Cancer by Katherine A. Schneider Pdf

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

Advances in Diagnosis and Management of Ovarian Cancer

Author : Samir A. Farghaly
Publisher : Springer Nature
Page : 247 pages
File Size : 46,6 Mb
Release : 2022-10-11
Category : Medical
ISBN : 9783031091698

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Advances in Diagnosis and Management of Ovarian Cancer by Samir A. Farghaly Pdf

This new edition features updated information on all aspects of the diagnosis and management of ovarian cancer. Embracing knowledge from around the world, this multidisciplinary book discusses current approaches to ovarian cancer that have helped stabilize the rate of both incidences and fatality for the disease. The chapters focus on genetic screening and advances in management, including the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues as well. The book is a must-have resource for wide range of practitioners who care for patients with ovarian cancer and researchers who study the disease.

Inherited Cancer Syndromes

Author : C. Neal Ellis
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 42,6 Mb
Release : 2010-10-29
Category : Medical
ISBN : 9781441968210

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Inherited Cancer Syndromes by C. Neal Ellis Pdf

The second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition.

The Genetics of Cancer

Author : B.A. Ponder,M.J. Waring
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401106771

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The Genetics of Cancer by B.A. Ponder,M.J. Waring Pdf

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Living with Hereditary Cancer Risk

Author : Kathy Steligo,Sue Friedman,Allison W. Kurian
Publisher : JHU Press
Page : 496 pages
File Size : 49,7 Mb
Release : 2022-09-27
Category : Health & Fitness
ISBN : 9781421444253

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Living with Hereditary Cancer Risk by Kathy Steligo,Sue Friedman,Allison W. Kurian Pdf

"This book provides a comprehensive overview of hereditary cancer for a general audience, with coverage of the genetic tests available for detecting risk for heritable cancers as well as options for medical and surgical treatment"--

Diagnostic Pathology: Familial Cancer Syndromes

Author : Vania Nosé
Publisher : Elsevier Health Sciences
Page : 897 pages
File Size : 44,7 Mb
Release : 2020-02-14
Category : Medical
ISBN : 9780323712057

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Diagnostic Pathology: Familial Cancer Syndromes by Vania Nosé Pdf

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome— and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout. Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other alterations; and details on personalized medicine targeted to specific genes Features more than 2,200 images throughout, including clinical and radiological images, algorithms, graphics, gross pathology, histology, and a wide range of special and immunohistochemical stains—all carefully annotated to highlight the most diagnostically significant factors Features time-saving bulleted text, key facts in each chapter, an extensive index, and numerous tables for quick reference and thorough understanding

Genetics for Health Professionals in Cancer Care

Author : Chris Jacobs,Lorraine Robinson,Patricia Webb
Publisher : Oxford University Press, USA
Page : 363 pages
File Size : 51,7 Mb
Release : 2014
Category : Medical
ISBN : 9780199672844

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Genetics for Health Professionals in Cancer Care by Chris Jacobs,Lorraine Robinson,Patricia Webb Pdf

This title equips health professionals with the knowledge and skills required for all aspects of managing cancer family history, discussing the challenges raised and providing practical guidance on setting up a cancer family history clinic in primary and secondary care.

Pediatric Cancer Genetics

Author : Nathaniel H. Robin,Meagan Farmer
Publisher : Elsevier Health Sciences
Page : 350 pages
File Size : 46,5 Mb
Release : 2017-08-22
Category : Medical
ISBN : 9780323495967

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Pediatric Cancer Genetics by Nathaniel H. Robin,Meagan Farmer Pdf

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Hereditary Tumors

Author : Heike Allgayer,Helga Rehder,Simone Fulda
Publisher : John Wiley & Sons
Page : 559 pages
File Size : 47,9 Mb
Release : 2009-05-13
Category : Medical
ISBN : 9783527627530

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Hereditary Tumors by Heike Allgayer,Helga Rehder,Simone Fulda Pdf

Summarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes. A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers.

Management of Hereditary Colorectal Cancer

Author : Jose G. Guillem,Garrett Friedman
Publisher : Springer Nature
Page : 213 pages
File Size : 42,7 Mb
Release : 2020-04-02
Category : Medical
ISBN : 9783030262341

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Management of Hereditary Colorectal Cancer by Jose G. Guillem,Garrett Friedman Pdf

This book provides a comprehensive review of the clinical management of hereditary colorectal cancer. The text focuses on six distinct patient groups: patients with early age-of-onset colorectal cancer and adenomas, patients with hamartomatous colorectal polyps, patients afflicted with familial adenomatous polyposis (FAP), patients with attenuated familial adenomatous polyposis (AFAP), patients with MYH associated polyposis (MAP), and patients afflicted with lynch syndrome (LS). Each chapter illustrates how clinicians utilize current technologies in genetic testing, pathological review, and endoscopic, surgical, and chemotherapeutic/immunotherapeutic approaches to manage these patient groups. Topics such as the timing of genetic testing, endoscopic screening and surveillance, prophylactic surgical options and chemo-preventive interventions are also discussed in concise yet precise detail. Written by experts in their fields, Management of Hereditary Colorectal Cancer: A Multidisciplinary Approach is a valuable and timely resource for gastroenterologists, surgeons, genetic counselors, medical oncologists, psychologists, and any health caregivers involved with the management of patients and families afflicted with a hereditary form of colorectal cancer.

A Guide to Cancer Genetics in Clinical Practice

Author : Sue Clark,
Publisher : tfm Publishing Limited
Page : 246 pages
File Size : 53,7 Mb
Release : 2009-05-01
Category : Medical
ISBN : 9781908986351

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A Guide to Cancer Genetics in Clinical Practice by Sue Clark, Pdf

FIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions.

Probably Someday Cancer

Author : Kim Horner
Publisher : University of North Texas Press
Page : 209 pages
File Size : 44,6 Mb
Release : 2019-02-15
Category : Biography & Autobiography
ISBN : 9781574417579

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Probably Someday Cancer by Kim Horner Pdf

After learning that she inherited a BRCA2 genetic mutation that put her at high risk for breast and ovarian cancer, Kim Horner’s doctors urged her to consider having a double mastectomy. But how do you decide whether to have a surgery to remove your breasts to reduce your risk for a disease you don’t have and may never get? Horner shares her struggle to answer that question in Probably Someday Cancer. The mother of a one-year-old boy, she wanted to do whatever would give her the best odds of being around for her son and protect her from breast cancer, which killed her grandmother and great-grandmother in their 40s. Which would give her the best chance at a long healthy life: a double mastectomy or frequent screenings to try to catch any cancer early? The answers weren’t that simple. Based on extensive research, interviews, and personal experience, Horner writes about how and why she ultimately opted for a double mastectomy—the same decision actress Angelina Jolie made for a similar genetic mutation—and the surprising diagnosis that followed. The book explores difficult truths that get overshadowed by upbeat messages about early detection and survivorship—the fact that screenings can miss cancers and that even early-stage breast cancers can spread and become fatal. Probably Someday Cancer is about the author’s efforts to push past her fear and anxiety. This book can help anyone facing hereditary risk of breast and ovarian cancer feel less alone and make informed decisions to protect their health and end the devastation that hereditary cancer has caused for generations in so many families.

Hereditary Colorectal Cancer

Author : Laura Valle,Stephen B. Gruber,Gabriel Capellá
Publisher : Springer
Page : 505 pages
File Size : 47,8 Mb
Release : 2018-05-04
Category : Medical
ISBN : 9783319742595

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Hereditary Colorectal Cancer by Laura Valle,Stephen B. Gruber,Gabriel Capellá Pdf

This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.