Cancer Vaccines

Author : Nima Rezaei,Mahsa Keshavarz-Fathi
Publisher : Academic Press
Page : 198 pages
File Size : 49,9 Mb
Release : 2018-10-17
Category : Medical
ISBN : 9780128140406

Get Book

Vaccines for Cancer Immunotherapy by Nima Rezaei,Mahsa Keshavarz-Fathi Pdf

Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer Presents the status of past and current vaccines for cancer treatment Considers advantages and disadvantages of different therapeutic cancer vaccines Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods Analyzes obstacles to development of therapeutic cancer vaccines Gives a view on future perspectives in the application of therapeutic cancer vaccines

Author : Natalia Savelyeva,Christian Ottensmeier
Publisher : Springer
Page : 0 pages
File Size : 46,7 Mb
Release : 2018-07-28
Category : Medical
ISBN : 331979552X

Get Book

Cancer Vaccines by Natalia Savelyeva,Christian Ottensmeier Pdf

This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment. This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.

Author : Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publisher : Unknown
Page : 392 pages
File Size : 55,5 Mb
Release : 2006
Category : Immunization
ISBN : 0660193922

Get Book

Canadian Immunization Guide by Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization Pdf

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Author : Peter L. Stern,Peter C. L. Beverley,Miles Carroll
Publisher : Cambridge University Press
Page : 304 pages
File Size : 41,6 Mb
Release : 2000-08-17
Category : Medical
ISBN : 0521622638

Get Book

Cancer Vaccines and Immunotherapy by Peter L. Stern,Peter C. L. Beverley,Miles Carroll Pdf

Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians and scientists review therapeutic cancer vaccine strategies against a variety of diseases and molecular targets. Intended for an interdisciplinary readership, their contributions cover the rationale, development, and implementation of vaccines in human cancer treatment, with specific reference to cancer of the cervix, breast, colon, bladder, and prostate, and to melanoma and lymphoma. They review target identification, delivery vectors and clinical trial design. The book begins and ends with lucid overviews from the editors, that discuss the most recent developments.

Author : Rimas Orentas,James W. Hodge,Bryon D. Johnson
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 52,7 Mb
Release : 2007-10-26
Category : Medical
ISBN : 9780470170106

Get Book

Cancer Vaccines and Tumor Immunity by Rimas Orentas,James W. Hodge,Bryon D. Johnson Pdf

Cancer Vaccines and Tumor Immunity offers a review of the basic scientific discoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation, T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.

Author : Luigi Buonaguro,Sjoerd Van Der Burg
Publisher : Academic Press
Page : 273 pages
File Size : 53,8 Mb
Release : 2022-03-04
Category : Science
ISBN : 9780128239025

Get Book

Cancer Vaccines as Immunotherapy of Cancer by Luigi Buonaguro,Sjoerd Van Der Burg Pdf

Cancer Vaccines as Immunotherapy of Cancer provides extensive and state-of-the-art information about the meaning, relevance and limitation of therapeutic cancer vaccines. It covers all the aspects involved in the vaccine research and development (identification of optimal target antigens, formulations, delivery strategies, adjuvants among others) as well as their use in combination with other immunomodulatory approaches. The book discusses topics such as identification of tumor associated and specific antigens, proteogenomic for identification of novel target tumor antigens, antigen-specific T cells, and Peptide and RNA based vaccines. Additionally, it covers oncolytic viruses for antigen delivery, cancer vaccine targeting viral antigens and combinatorial immunotherapy strategies. Written by leading experts worldwide, this is a valuable resource for cancer researchers, oncologists and members of biomedical field who wants to understand in depth the recent findings in the field of cancer vaccines. Describes the state-of-the-art of the research and development of therapeutic cancer vaccines Presents detailed diagrams to help the reader understand the functionality of each type of vaccine discussed Encompasses recent findings in the field through chapters written by leading experts worldwide

Author : Natalia Savelyeva,Christian Ottensmeier
Publisher : Springer
Page : 210 pages
File Size : 40,6 Mb
Release : 2017-07-10
Category : Medical
ISBN : 9783319239101

Get Book

Cancer Vaccines by Natalia Savelyeva,Christian Ottensmeier Pdf

This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment. This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.

Author : Adrian Bot,Mihail Obrocea,Francesco M. Marincola
Publisher : CRC Press
Page : 280 pages
File Size : 52,9 Mb
Release : 2015-05-06
Category : Medical
ISBN : 9781841848303

Get Book

Cancer Vaccines by Adrian Bot,Mihail Obrocea,Francesco M. Marincola Pdf

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: From Research to Clinical Practice is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist. Cancer Vaccines: From Research to Clinical Practice: Analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential Discusses "theranostics" as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them

Author : Amita Sarkar
Publisher : Discovery Publishing House
Page : 324 pages
File Size : 41,7 Mb
Release : 2009
Category : Cancer
ISBN : 818356397X

Get Book

Cancer Vaccine by Amita Sarkar Pdf

Author : Nathan Elliot
Publisher : Nova Publishers
Page : 136 pages
File Size : 49,9 Mb
Release : 2006
Category : Cancer
ISBN : 1594549680

Get Book

Cancer Vaccines by Nathan Elliot Pdf

Cancer vaccines are intended either to treat existing cancers (therapeutic vaccines) or to prevent the development of cancer (prophylactic vaccines). Both types of vaccines have the potential to reduce the burden of cancer. Treatment or therapeutic vaccines are administered to cancer patients and are designed to strengthen the body's natural defences against cancers that have already developed. These types of vaccines may prevent the further growth of existing cancers, prevent the recurrence of treated cancers, or eliminate cancer cells not killed by prior treatments. Prevention or prophylactic vaccines, on the other hand, are administered to healthy individuals and are designed to target cancer-causing viruses and prevent viral infection. This new book presents important and timely research in this dynamic field.

Author : Mahfoozur Rahman,Sarwar Beg,Waleed H Almalki,Nabil A. Alhakamy,Hani Choudhry
Publisher : Academic Press
Page : 496 pages
File Size : 46,7 Mb
Release : 2022-03-03
Category : Business & Economics
ISBN : 9780128236871

Get Book

Nanotherapeutics in Cancer Vaccination and Challenges by Mahfoozur Rahman,Sarwar Beg,Waleed H Almalki,Nabil A. Alhakamy,Hani Choudhry Pdf

Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy. Presents the progress made in cancer medicines from conventional to targeted therapy Covers the present state-of-the-art of cancer nanomedicines and upcoming therapeutic cancer vaccination Contains a focus on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, siRNA

Author : Michael A. Morse,Timothy M. Clay,H. Kim Lyerly
Publisher : Springer Science & Business Media
Page : 585 pages
File Size : 46,9 Mb
Release : 2004-01-28
Category : Medical
ISBN : 9781592596805

Get Book

Handbook of Cancer Vaccines by Michael A. Morse,Timothy M. Clay,H. Kim Lyerly Pdf

An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.

Author : An M. T. Van Nuffel,Caroline Boudousquié,Sandra Tuyaerts
Publisher : Frontiers Media SA
Page : 196 pages
File Size : 53,6 Mb
Release : 2019-12-27
Category : Electronic
ISBN : 9782889631605

Get Book

Approaches to Advance Cancer Vaccines to Clinical Utility by An M. T. Van Nuffel,Caroline Boudousquié,Sandra Tuyaerts Pdf

Although cancer vaccines have yielded promising results both in vitro and in animal models, their translation into clinical application has not been very successful so far. Through the success of immune checkpoint inhibitors, the tumor immunotherapy field revived and led to important new insights. A better understanding of the functional capacity of different dendritic cell (DC) subsets and the immunogenicity of tumor antigens, more particularly of neoantigens, have important implications for the improvement of cancer vaccines. These insights can guide the development of novel strategies, to enhance the clinical utility of cancer vaccines. The aim of this Research Topic is therefore to provide a comprehensive overview of current issues regarding cancer vaccine development with an emphasis on novel approaches toward enhancing their efficacy.

Author : Stephanie E. B. McArdle,Alan Graham Pockley,Pål Johansen,Graham Pawelec
Publisher : Frontiers Media SA
Page : 284 pages
File Size : 40,6 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9782889717293

Get Book

Cancer Vaccines: Time to Think Differently! by Stephanie E. B. McArdle,Alan Graham Pockley,Pål Johansen,Graham Pawelec Pdf

Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee
Publisher : National Academies Press
Page : 118 pages
File Size : 45,5 Mb
Release : 2003-12-26
Category : Medical
ISBN : 9780309086103

Get Book

Immunization Safety Review by Institute of Medicine,Board on Health Promotion and Disease Prevention,Immunization Safety Review Committee Pdf

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.