Cardiotoxicity

Author : Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi
Publisher : Academic Press
Page : 470 pages
File Size : 49,8 Mb
Release : 2016-11-11
Category : Medical
ISBN : 9780128026472

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Anticancer Treatments and Cardiotoxicity by Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi Pdf

Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Author : Wenyong Tan
Publisher : Unknown
Page : 0 pages
File Size : 49,5 Mb
Release : 2018
Category : Cardiovascular agents
ISBN : 1838818227

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Cardiotoxicity by Wenyong Tan Pdf

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 48,5 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Giorgio Minotti
Publisher : John Wiley & Sons
Page : 360 pages
File Size : 45,5 Mb
Release : 2010-03-25
Category : Science
ISBN : 0470660384

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Cardiotoxicity of Non-Cardiovascular Drugs by Giorgio Minotti Pdf

Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.

Author : Wenyong Tan
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 54,5 Mb
Release : 2018-11-14
Category : Medical
ISBN : 9781789842371

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Cardiotoxicity by Wenyong Tan Pdf

Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Author : Atooshe Rohani
Publisher : Springer Nature
Page : 122 pages
File Size : 49,9 Mb
Release : 2021-04-26
Category : Medical
ISBN : 9783030711559

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Clinical Cases in Cardio-Oncology by Atooshe Rohani Pdf

This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with ​cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with ​cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.

Author : Manuela Fiuza
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 43,9 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9789535102731

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Cardiotoxicity of Oncologic Treatments by Manuela Fiuza Pdf

The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.

Author : Tamer M. A. Mohamed,Javid Moslehi,Jonathan Satin
Publisher : Frontiers Media SA
Page : 142 pages
File Size : 51,8 Mb
Release : 2022-01-05
Category : Science
ISBN : 9782889719549

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Recent Advances in Cardiotoxicity Testing by Tamer M. A. Mohamed,Javid Moslehi,Jonathan Satin Pdf

Author : Susan Currie,Margaret Rose Cunningham,Michael Cross,Helen Louise Maddock
Publisher : Frontiers Media SA
Page : 161 pages
File Size : 44,5 Mb
Release : 2022-10-11
Category : Medical
ISBN : 9782832502105

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Anti-Cancer Drug-Induced Cardiotoxicity by Susan Currie,Margaret Rose Cunningham,Michael Cross,Helen Louise Maddock Pdf

Author : Feng Sun,Shusen Sun
Publisher : Frontiers Media SA
Page : 156 pages
File Size : 44,5 Mb
Release : 2023-08-01
Category : Medical
ISBN : 9782832530931

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Drug-induced cardiotoxicity: Identification, assessment, prevention and management by Feng Sun,Shusen Sun Pdf

Author : Anonim
Publisher : Unknown
Page : 116 pages
File Size : 53,6 Mb
Release : 1984
Category : Anthracyclines
ISBN : UCR:31210005574023

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Proceedings of the Workshop on Mitoxantrone Cardiotoxicity and the Workshop on Clinical Evaluation of Anthracycline Cardiotoxicity by Anonim Pdf

Author : René Packard,Eric H. Yang
Publisher : Frontiers Media SA
Page : 142 pages
File Size : 42,7 Mb
Release : 2023-02-03
Category : Medical
ISBN : 9782832513439

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Novel mechanisms, imaging approaches and management strategies for anthracycline-induced cardiotoxicity by René Packard,Eric H. Yang Pdf

Author : Michael S. Ewer
Publisher : PMPH-USA
Page : 508 pages
File Size : 43,9 Mb
Release : 2013
Category : Drugs
ISBN : 1607950405

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Cancer and the Heart by Michael S. Ewer Pdf

The book begins with the basic science behind the medical applications of the knowledge: cardiovascular biology, pathways, and their relationship to cancer treatment and principles of chemotherapy and immunotherapy. The second section consists of an overview and classification of anti-cancer drugs and a look at their cardiotoxicity. The third section looks at cardiac imaging in the cancer patient, including cardiac ultrasound, Doppler imaging, nuclear imaging, magnetic resonance imaging, and computed tomography in the cancer patient. In section four, management of cardiac disease in the cancer patient is discussed, including cardiac rhythm disturbances and heart failure. Cardiac emergencies and interventions are described as is preoperative assessment of the cancer patient for non- cardiovascular surgery. The final section includes a range of topics such as the pericardium, cardiovascular effects of endocrine treatments, primary cardiac tumors and malignancies of the myocardium and pericardium. Cardiac monitoring during clinical trials and pulmonary concerns are also addressed, as are psychosocial, social, economic, and legal issues of the cancer patient with heart disease.

Author : Imteyaz Qamar,Pawan Kumar Maurya
Publisher : Academic Press
Page : 278 pages
File Size : 44,7 Mb
Release : 2022-05-26
Category : Science
ISBN : 9780323904629

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Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology by Imteyaz Qamar,Pawan Kumar Maurya Pdf

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

Author : Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen
Publisher : Unknown
Page : 162 pages
File Size : 48,9 Mb
Release : 2021
Category : Electronic
ISBN : 3318067903

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Endocrine and Metabolic Late Effects in Cancer Survivors by Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen Pdf

This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.