Anti Cancer Drug Induced Cardiotoxicity

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Anti-Cancer Drug-Induced Cardiotoxicity

Author : Susan Currie,Margaret Rose Cunningham,Michael Cross,Helen Louise Maddock
Publisher : Frontiers Media SA
Page : 161 pages
File Size : 49,6 Mb
Release : 2022-10-11
Category : Medical
ISBN : 9782832502105

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Anti-Cancer Drug-Induced Cardiotoxicity by Susan Currie,Margaret Rose Cunningham,Michael Cross,Helen Louise Maddock Pdf

Cardiotoxicity

Author : Wenyong Tan
Publisher : Unknown
Page : 0 pages
File Size : 53,8 Mb
Release : 2018
Category : Cardiovascular agents
ISBN : 1838818227

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Cardiotoxicity by Wenyong Tan Pdf

Cardiotoxicity

Author : Wenyong Tan
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 40,6 Mb
Release : 2018-11-14
Category : Medical
ISBN : 9781789842371

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Cardiotoxicity by Wenyong Tan Pdf

Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 47,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Anticancer Treatments and Cardiotoxicity

Author : Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi
Publisher : Academic Press
Page : 470 pages
File Size : 47,5 Mb
Release : 2016-11-11
Category : Medical
ISBN : 9780128026472

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Anticancer Treatments and Cardiotoxicity by Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi Pdf

Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology

Author : Imteyaz Qamar,Pawan Kumar Maurya
Publisher : Academic Press
Page : 278 pages
File Size : 52,9 Mb
Release : 2022-05-26
Category : Science
ISBN : 9780323904629

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Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-oncology by Imteyaz Qamar,Pawan Kumar Maurya Pdf

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

Cardiotoxicity

Author : Wenyong Tan
Publisher : Unknown
Page : 162 pages
File Size : 41,7 Mb
Release : 2018
Category : Diseases of the circulatory (Cardiovascular) system
ISBN : 1789842387

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Cardiotoxicity by Wenyong Tan Pdf

Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Cardiovascular Magnetic Resonance Spectroscopy

Author : Saul Schaefer,Robert S. Balaban
Publisher : Springer
Page : 0 pages
File Size : 48,9 Mb
Release : 2012-10-06
Category : Science
ISBN : 1461365473

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Cardiovascular Magnetic Resonance Spectroscopy by Saul Schaefer,Robert S. Balaban Pdf

The application of magnetic resonance spectroscopy (MRS) to the cardiovascular system is a relatively new phenomenon. Its ability to noninvasively examine myocardial metabolism has led to its use to answer basic questions in animal models of normal and diseased myocardium. Extension of these investigations into the realm of human myocardial metabolism has been made possible by the advent of relatively high-field magnets with spectroscopy capabilities and sufficient bore dimensions to allow human studies. While ongoing and future studies promise to enhance our understanding of myocardial metabolism, their success will, in part, depend on a thorough understanding of the technical and biologic aspects of cardiovascular MRS, as well as the current state of research in the many areas encompassed by this discipline. It is with concept that the present monograph has been written. The organization and content should lend this book to both the beginning reader who is interested but not conversant in cardiovascular MRS, as well as to the active investigator who wishes to refer to a volume that deals with the many issues of this field in a concise but complete manner. The monograph is structured with a general overview of the field, followed by a section addressing the technical issues of cardiovascular MRS. The next section is devoted to biologic issues of both normal and abnormal myocardial metabolism, primarily devoted to investigations employing phosphorus-31. This is followed by a section dealing with more specialized issues, generally involving other nuclei such as protons, carbon, and sodium. Finally, the clinical applications of cardiovascular MRS are addressed.

Heart Failure: A Companion to Braunwald's Heart Disease E-Book

Author : G. Michael Felker,Douglas L. Mann
Publisher : Elsevier Health Sciences
Page : 784 pages
File Size : 54,8 Mb
Release : 2019-02-06
Category : Medical
ISBN : 9780323609883

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Heart Failure: A Companion to Braunwald's Heart Disease E-Book by G. Michael Felker,Douglas L. Mann Pdf

Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM’s Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).

Skin and the Heart

Author : Carmen Salavastru,Dedee F. Murrell,James Otton
Publisher : Springer Nature
Page : 494 pages
File Size : 49,9 Mb
Release : 2021-03-10
Category : Medical
ISBN : 9783030547790

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Skin and the Heart by Carmen Salavastru,Dedee F. Murrell,James Otton Pdf

This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment. Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa. Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

Cancer Treatment and the Heart

Author : Franco M. Muggia,Michael D. Green,James L. Speyer
Publisher : Unknown
Page : 416 pages
File Size : 46,5 Mb
Release : 1992
Category : Literary Criticism
ISBN : UOM:39015029195248

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Cancer Treatment and the Heart by Franco M. Muggia,Michael D. Green,James L. Speyer Pdf

A foundational investigation of disorders of the heart resulting from cancer treatment, with conclusions about common mechanisms. Seventeen contributed chapters are arranged in five parts: cytotoxic myocardial disease--preclinical study, cytotoxic myocardial disease--clinical study, myocardial disease--radiation and biologics, pericardial disease, and other cardiovascular disease. Annotation copyright by Book News, Inc., Portland, OR

Cardiotoxicity of Oncologic Treatments

Author : Manuela Fiuza
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 50,7 Mb
Release : 2012-03-28
Category : Medical
ISBN : 9789535102731

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Cardiotoxicity of Oncologic Treatments by Manuela Fiuza Pdf

The possibility of getting a cardiovascular disease or cancer increases with advancing age. At the same time, relevant improvements in cancer therapy have resulted in the improvement of quality of life and the increasement of the survival rate of such patients. As a result we have larger number of patients that experience the cardiac side effects of chemotherapy. The extent of cardiotoxicity is variable, depending on the type of drug used, combination with other drugs, prior mediastinal radiotherapy and the presence of cardiovascular risk factors or history of heart disease. Early detection of the patients proneness for developing cardiotoxicity is the key issue to decrease morbidity and mortality. It also facilitates more tailored therapeutic interventions. Therefore, the collaboration and interaction of cardiology and oncology may contribute to reducing the cardiovascular adverse effects and improving the results in the treatment of patients with cancer.

Cancer and the Heart

Author : Michael S. Ewer
Publisher : PMPH-USA
Page : 508 pages
File Size : 53,8 Mb
Release : 2013
Category : Drugs
ISBN : 1607950405

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Cancer and the Heart by Michael S. Ewer Pdf

The book begins with the basic science behind the medical applications of the knowledge: cardiovascular biology, pathways, and their relationship to cancer treatment and principles of chemotherapy and immunotherapy. The second section consists of an overview and classification of anti-cancer drugs and a look at their cardiotoxicity. The third section looks at cardiac imaging in the cancer patient, including cardiac ultrasound, Doppler imaging, nuclear imaging, magnetic resonance imaging, and computed tomography in the cancer patient. In section four, management of cardiac disease in the cancer patient is discussed, including cardiac rhythm disturbances and heart failure. Cardiac emergencies and interventions are described as is preoperative assessment of the cancer patient for non- cardiovascular surgery. The final section includes a range of topics such as the pericardium, cardiovascular effects of endocrine treatments, primary cardiac tumors and malignancies of the myocardium and pericardium. Cardiac monitoring during clinical trials and pulmonary concerns are also addressed, as are psychosocial, social, economic, and legal issues of the cancer patient with heart disease.

Cardio-Oncology

Author : Roberta A. Gottlieb,Puja K Mehta
Publisher : Academic Press
Page : 356 pages
File Size : 54,6 Mb
Release : 2016-11-26
Category : Medical
ISBN : 9780128035535

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Cardio-Oncology by Roberta A. Gottlieb,Puja K Mehta Pdf

Cardio-Oncology: Principles, Prevention and Management is a clinical volume that focuses on the basic science of cardio-oncology, addresses cardiotoxicity as a consequence of cancer therapy, and discusses prevention, diagnosis and management of cardiovascular disease in patients with cancer. This comprehensive volume presents unique perspectives ranging from basic science to clinical medicine in the field of cardio-oncology. It would be a valuable resource for cardiologists, oncologists, internists, and pediatricians caring for patients with cancer who have cardiovascular risk factors, as well as for cardio-oncology researchers. Covers basic science of cardio-oncology to provide readers with the necessary background Addresses cardiotoxicity related to current cancer therapeutic modalities Discusses diagnostic and management approaches of patients with underlying cardiac risk factors as well as otherwise healthy cancer patients

Anticancer Drugs

Author : Niamh M O’Boyle,Mary J Meegan
Publisher : MDPI
Page : 214 pages
File Size : 44,5 Mb
Release : 2019-10-11
Category : Medical
ISBN : 9783039215867

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Anticancer Drugs by Niamh M O’Boyle,Mary J Meegan Pdf

The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this Special Issue of Pharmaceuticals, we highlight the opportunities and challenges in the discovery and design of innovative cancer therapies, novel small-molecule cancer drugs and antibody–drug conjugates, with articles covering a variety of anticancer therapies and potential relevant disease states and applications. Significant efforts are being made to develop and improve cancer treatments and to translate basic research findings into clinical use, resulting in improvements in survival rates and quality of life for cancer patients. We demonstrate the possibilities and scope for future research in these areas and also highlight the challenges faced by scientists in the area of anticancer drug development leading to improved targeted treatments and better survival rates for cancer patients.