Cartilage

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The Illustrative Book of Cartilage Repair

Author : Deepak Rajkumar Goyal
Publisher : Springer Nature
Page : 278 pages
File Size : 54,6 Mb
Release : 2020-10-26
Category : Medical
ISBN : 9783030471545

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The Illustrative Book of Cartilage Repair by Deepak Rajkumar Goyal Pdf

This book employs a wealth of high-quality illustrations to provide the reader with a detailed understanding of the anatomy and the histology of the cartilage, the etiology and the classification of the cartilage lesions, and the numerous techniques employed for cartilage repair. Detailed attention is devoted to healthy cartilage, to each stage in the degenerative process, and to the response of the cartilage to the treatment. Imaging of the damaged and the repaired cartilage, as well as the information on the biomechanics are provided in great detail. The chapters on the techniques cover a wide range of approaches: marrow stimulation techniques, osteochondral cylinder transfer techniques, first, second and third generation autologous chondrocyte implantation techniques, allografts, cell-based therapies, orthobiologic approaches, and the role of 3D printing. The chapters closes with a consideration of the success of rehabilitation devices and the long-term results of cartilage repair.The book will be invaluable for all general orthopaedic and arthroscopic surgeons seeking a deeper knowledge of cartilage science and will help to dispel the confusion that still surrounds the reparative treatment. The authors are recognized experts in the fields of cartilage histology, assessment, classification, and repair.

Bones and Cartilage

Author : Brian K. Hall
Publisher : Academic Press
Page : 920 pages
File Size : 49,9 Mb
Release : 2014-12-23
Category : Medical
ISBN : 9780124166851

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Bones and Cartilage by Brian K. Hall Pdf

Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Articular Cartilage

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi
Publisher : CRC Press
Page : 442 pages
File Size : 47,8 Mb
Release : 2013-03-21
Category : Medical
ISBN : 9781439853245

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Articular Cartilage by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi Pdf

Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.

Articular Cartilage of the Knee

Author : Harpal K. Gahunia,Allan E. Gross,Kenneth P.H. Pritzker,Paul S. Babyn,Lucas Murnaghan
Publisher : Springer
Page : 0 pages
File Size : 49,8 Mb
Release : 2020-05-10
Category : Medical
ISBN : 1493975854

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Articular Cartilage of the Knee by Harpal K. Gahunia,Allan E. Gross,Kenneth P.H. Pritzker,Paul S. Babyn,Lucas Murnaghan Pdf

Covering both pediatric and adult populations, this comprehensive text covers the diverse topics related to the health, disease and therapy of articular cartilage of the knee, from basic principles to future directions for research. This vast array of information is arranged into eight sections, encompassing a number of relevant disciplines and covering, in turn, normal articular cartilage, aging and degeneration, evaluation and assessment, non-surgical approaches, surgical approaches, qualitative and quantitative assessment of repair, research into cartilage repair and engineering, and future prospects for therapy. Each chapter is amply referenced and self-contained for independent study and reference. Scoring systems for knee cartilage assessment are included in four appendices as well, rounding out the presentation. A multidisciplinary collection of basic, translational and clinical material, Articular Cartilage of the Knee is a singular resource for orthopedic surgeons, rheumatologists, pathologists and the broad spectrum of professionals working with articular cartilage.

Cartilage Injury of the Knee

Author : Aaron J. Krych,Leela C. Biant,Andreas H. Gomoll,João Espregueira-Mendes,Alberto Gobbi,Norimasa Nakamura
Publisher : Springer Nature
Page : 345 pages
File Size : 46,9 Mb
Release : 2021-08-31
Category : Medical
ISBN : 9783030780517

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Cartilage Injury of the Knee by Aaron J. Krych,Leela C. Biant,Andreas H. Gomoll,João Espregueira-Mendes,Alberto Gobbi,Norimasa Nakamura Pdf

Cartilage injuries of the knee are common, and diagnosis and treatment options have continued to evolve. This book focuses on current non-operative and surgical treatment strategies for articular cartilage injuries, highlighting the controversies and different approaches from an international perspective. This book includes information on the basic science of cartilage structure and function, expert perspectives on imaging and diagnosing, as well as work-up of athletes and patients presenting with acute or chronic cartilage injury. It also provides an evidence base for current cutting-edge cartilage repair and restoration. Written by leading experts in the field, the book, published in collaboration with ISAKOS and ICRS, is vital reading for orthopaedic and sports medicine surgeons, fellows and residents. It is also of interest to sports trainers, physiotherapists, medical students, postgraduate students, and physical medicine and rehabilitation specialists.

Articular Cartilage Dynamics

Author : David W. Smith,Bruce S. Gardiner,Lihai Zhang,Alan J. Grodzinsky
Publisher : Springer
Page : 738 pages
File Size : 40,5 Mb
Release : 2018-11-19
Category : Technology & Engineering
ISBN : 9789811314742

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Articular Cartilage Dynamics by David W. Smith,Bruce S. Gardiner,Lihai Zhang,Alan J. Grodzinsky Pdf

This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters.

Dynamics of Bone and Cartilage Metabolism

Author : Markus J. Seibel,Simon P. Robins,John P. Bilezikian
Publisher : Elsevier
Page : 920 pages
File Size : 47,5 Mb
Release : 2006-07-24
Category : Medical
ISBN : 008045626X

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Dynamics of Bone and Cartilage Metabolism by Markus J. Seibel,Simon P. Robins,John P. Bilezikian Pdf

This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, Dynamics of Bone and Cartilage Metabolism, Second Edition, is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases. Part I provides an up-to-date account of current knowledge of the structure, biosynthesis and molecular biology of the major tissue components Part II covers the organizational structure and cellular metabolism of bone and cartilage Part III deals with the utility of components specific to bone and cartilage as biomarkers of health and disease

A Tissue Regeneration Approach to Bone and Cartilage Repair

Author : Hala Zreiqat,Colin R. Dunstan,Vicki Rosen
Publisher : Springer
Page : 254 pages
File Size : 55,5 Mb
Release : 2014-12-05
Category : Technology & Engineering
ISBN : 9783319132662

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A Tissue Regeneration Approach to Bone and Cartilage Repair by Hala Zreiqat,Colin R. Dunstan,Vicki Rosen Pdf

Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Handbook of Histology Methods for Bone and Cartilage

Author : Yuehuei H. An,Kylie L. Martin
Publisher : Springer Science & Business Media
Page : 588 pages
File Size : 51,7 Mb
Release : 2003-05-01
Category : Medical
ISBN : 9781592594177

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Handbook of Histology Methods for Bone and Cartilage by Yuehuei H. An,Kylie L. Martin Pdf

Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors’ own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.

Biophysics and Biochemistry of Cartilage by NMR and MRI

Author : Yang Xia,Konstantin Momot
Publisher : Royal Society of Chemistry
Page : 760 pages
File Size : 45,5 Mb
Release : 2016-11-16
Category : Science
ISBN : 9781782621331

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Biophysics and Biochemistry of Cartilage by NMR and MRI by Yang Xia,Konstantin Momot Pdf

This unique book describes the latest information in the fundamental understanding of the biophysics and biochemistry of articular cartilage using the state-of-the-art practices in NMR and MRI. This is the first book of its kind, written by physicists and chemists on this important tissue, whose degradation contributes to osteoarthritis and related joint diseases. Connecting the fundamental science with the clinical imaging applications, the experts Editors provide an authoritative addition to the literature. Ideal for practising physical scientists and radiologists with an interest in the fundamental science as well as instrument manufacturers and clinical researchers working with articular cartilage.

Cartilage Repair and Joint Preservation of the Knee

Author : Tom Minas
Publisher : Elsevier Health Sciences
Page : 291 pages
File Size : 41,6 Mb
Release : 2021-10-01
Category : Medical
ISBN : 9780323698092

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Cartilage Repair and Joint Preservation of the Knee by Tom Minas Pdf

Fully updated with recent technologies, current scientific knowledge, and the latest techniques, A Primer in Cartilage Repair and Joint Preservation of the Knee, 2nd Edition, presents the full range of treatment options for a changing, increasingly younger patient population. Using an easy-to-follow, step-by-step approach, Dr. Thomas Minas clearly teaches how to meet the new challenges of cartilage repair by utilizing the latest techniques and technologies, including advances in orthobiologics. Surgical photographs, abundant illustrations, and procedural videos provide detailed visual guidance. Details the systematic approach to diagnosis, patient management, surgical techniques, and rehabilitation for a variety of problems. Covers current scientific knowledge of cartilage properties, the etiology of damage and the intrinsic repair and regeneration processes. Helps you select the best treatment course for each patient through extensive coverage of options from non-surgical to mini-incision total knee arthroplasty. Discusses the latest evidence, research and challenges associated with new techniques such as MACI, ACI, HTO, DFO, and more. Features new and expanded coverage of the latest advances in orthobiologics including platelet-rich plasma, bone marrow stem cells, fat stem cells, scaffolds and much more. Includes key topics such as printed 3-D cartilage structures and the management of secondary cartilage lesions. Contains high-quality illustrations and surgical photos, as well as new videos that provide clear instructions on how to perform key procedures. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Articular Cartilage

Author : Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi
Publisher : CRC Press
Page : 442 pages
File Size : 55,8 Mb
Release : 2017-01-06
Category : Medical
ISBN : 9781351722322

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Articular Cartilage by Kyriacos A. Athanasiou,Eric M. Darling,Jerry C. Hu,Grayson D. DuRaine,A. Hari Reddi Pdf

Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.

Cartilage Repair and Regeneration

Author : Alessandro Rozim Zorzi,João Batista de Miranda
Publisher : BoD – Books on Demand
Page : 230 pages
File Size : 46,6 Mb
Release : 2018-02-14
Category : Technology & Engineering
ISBN : 9789535137887

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Cartilage Repair and Regeneration by Alessandro Rozim Zorzi,João Batista de Miranda Pdf

This work is the result of a partnership that began in 2011, when I received for the first time the invitation to be the scientific editor of a book on bone grafting, by the still little publisher known as InTech. Now six years later, InTech has grown and thrived. My respect and warm approval for the quality of the publisher's work only increased. The hyaline cartilage is a tissue that challenges tissue engineering and regenerative medicine because of its avascular nature. In the 11 chapters of this book, the reader will find texts written by researchers working on advanced topics related to basic laboratory research, as well as excellent reviews on the clinical use of currently available therapies.

Cartilage Tissue Engineering

Author : Martin J. Stoddart,Elena Della Bella,Angela R. Armiento
Publisher : Springer Nature
Page : 392 pages
File Size : 49,6 Mb
Release : 2022-11-10
Category : Science
ISBN : 9781071628393

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Cartilage Tissue Engineering by Martin J. Stoddart,Elena Della Bella,Angela R. Armiento Pdf

This detailed book brings together a collection of methodologies, from the most basic to the more complex, that provides researchers with a platform they can use to embark on a cartilage research career. To aid in the search for novel therapies for cartilage regeneration, this volume addresses 3D cartilage models, challenges associated with RNA and protein extraction, imaging, gene transfer, as well as stable differentiation and variations in cell phenotype from different tissue origins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Cartilage Tissue Engineering serves as an ideal guide for researchers working to advance the vital study of cartilage biology and repair.

Cartilage Tissue and Knee Joint Biomechanics

Author : Amirsadegh Rezazadeh Nochehdehi,Fulufhelo Nemavhola,Sabu Thomas,Hanna J. Maria
Publisher : Elsevier
Page : 765 pages
File Size : 50,9 Mb
Release : 2023-09-18
Category : Technology & Engineering
ISBN : 9780323907217

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Cartilage Tissue and Knee Joint Biomechanics by Amirsadegh Rezazadeh Nochehdehi,Fulufhelo Nemavhola,Sabu Thomas,Hanna J. Maria Pdf

Cartilage, Tissue and Knee Joint Biomechanics: Fundamentals, Characterization and Modelling is a cutting-edge multidisciplinary book specifically focused on modeling, characterization and related clinical aspects. The book takes a comprehensive approach towards mechanics, fundamentals, morphology and properties of Cartilage Tissue and Knee Joints. Leading researchers from health science, medical technologists, engineers, academics, government, and private research institutions across the globe have contributed to this book. This book is a very valuable resource for graduates and postgraduates, engineers and research scholars. The content also includes comprehensive real-world applications. As a reference for the total knee arthroplasty, this book focuses deeply on existing related theories (including: histology, design, manufacturing and clinical aspects) to assist readers in solving fundamental and applied problems in biomechanical and biomaterials characterization, modeling and simulation of human cartilages and cells. For biomedical engineers dealing with implants and biomaterials for knee joint injuries, this book will guide you in learning the knee anatomy, range of motion, surgical procedures, physiological loading and boundary conditions, biomechanics of connective soft tissues, type of injuries, and more. Provides a comprehensive resource on the knee joint and its connective soft tissues; content included spans biomechanics, biomaterials, biology, anatomy, imaging and surgical procedure Covers ISO and FDA based regulatory control and compliance in the manufacturing process Includes discussions on the relationship between knee anatomical parameters and knee biomechanics