Cell Death In Mammalian Ovary

Author : Gerardo H. Vázquez-Nin,María Luisa Escobar,M. De Felici,Olga Margarita Echeverría,Francesca Gioia Klinger
Publisher : Springer Science & Business Media
Page : 233 pages
File Size : 52,6 Mb
Release : 2011-05-26
Category : Medical
ISBN : 9789400711341

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Cell Death in Mammalian Ovary by Gerardo H. Vázquez-Nin,María Luisa Escobar,M. De Felici,Olga Margarita Echeverría,Francesca Gioia Klinger Pdf

The ovary is a suitable organ for studying the processes of cell death. Cell death was first described in the rabbit ovary (Graaffian follicles), the phenomenon being called ‘chromatolysis’. To date, it is recognized that various forms of cell death (programmed cell death, apoptosis and autophagy) are essential components of ovarian development and function. Programmed cell death is responsable for the ovarian endowment of primordial follicles around birth; in the prepuberal and adult period, apoptosis is a basic mechanism by which oocytes are eliminated by cancer therapies and environmental toxicants; in the ovarian cycle, follicular atresia and luteal regression involve follicular cell apoptosis. Finally, abnormalities in cell death processes may lead to ovarian disease such as cancer and chemoresistance. In this book, after an introductory description of various forms of cell death and of the ovary development and function in mammals, the processes of cell death in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels and analyzed in the embryonic, prepuberal and adult ovary. A complex array of molecular pathways triggered by extrinsic and intrinsic signals able tor induce or suppress cell death in the same cell, according to cell type and ovary developmental stage, emerges. Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle. The book conveys information useful to the updating of biologists and physicians who are interested to the ovary biology and functions. Hopefully it should provide also clues for stimulating novel experiments in the study of cell death in the mammalian ovary still at an early stage.

Author : Jonathan L. Tilly,Jerome F. Strauss,Martin Tenniswood
Publisher : Springer Science & Business Media
Page : 458 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461219446

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Cell Death in Reproductive Physiology by Jonathan L. Tilly,Jerome F. Strauss,Martin Tenniswood Pdf

The regulation of cell death in various reproductive tissues, as in other ma jor organ systems of the body, has become a focal point of research activity in many laboratories over the past few years. As such, the need for a "for mal" meeting to highlight recent work in this field, as well as to integrate knowledge from other sources (such as investigators working on cell death in cancer and immune function) in the broad context of identifying con served pathways that coordinate life-and-death decisions in diverse cell types, became apparent. Therefore, the goals of the Scientific Committee of the International Symposium on Cell Death in Reproductive Physiology, spon sored by Serono Symposia USA, were already predetermined by this need. Simply stated, we sought to bring together for the first time a select cohort of reproductive biologists and cell death researchers, many but not all cho sen based on their pioneering efforts in elucidating the fundamental aspects of apoptosis in reproductive and nonreproductive tissues, as a means to re view the current status of the field, foster new ideas, and promote scientific collaborations. In the ensuing chapters of this book, summaries of work dis cussed at the meeting are presented to emphasize both the diversity and the similarities in the occurrence and regulation of apoptosis in tissues of the male and female reproductive systems.

Author : Katharina Spanel-Borowski
Publisher : Springer Science & Business Media
Page : 150 pages
File Size : 55,6 Mb
Release : 2012-10-12
Category : Medical
ISBN : 9783642305351

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Atlas of the Mammalian Ovary by Katharina Spanel-Borowski Pdf

In the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.

Author : Aaron J.W. Hsueh,David W. Schomberg
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 52,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461383369

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Ovarian Cell Interactions by Aaron J.W. Hsueh,David W. Schomberg Pdf

Due to the introduction of molecular and cellular biology approaches, our understanding of ovarian physiology has reached a new level during the last few years. The present volume provides a new perspective on the ovary from molecular and cellular to whole organ levels, from non-mammalian and rodent to human levels and from paracrine, neuroendocrine and endocrine levels as well. These papers represent the proceedings of the Ninth Ovarian Workshop sponsored by Serono Symposia, USA, July 9-11, 1992 in Chapel Hill, North Carolina.

Author : Yannick Bailly
Publisher : BoD – Books on Demand
Page : 526 pages
File Size : 51,5 Mb
Release : 2013-04-17
Category : Science
ISBN : 9789535110620

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Autophagy - A Double-Edged Sword by Yannick Bailly Pdf

The chapters in this book review the latest advances in the molecular mechanisms of autophagy, highlighting some of the most challenging research topics. The focus is mainly on how this basic cell defense mechanism comes into play in various pathologies, including liver diseases, myopathies, infectious diseases, cancers and neurodegenerative diseases. In these diseases, the contradictory autophagy roles of cell survival versus cell death emphasize the necessity of taking into account this double-edged nature in future development of already promising, autophagy- modulating, therapies.

Author : C. S. Potten
Publisher : Oxford University Press, USA
Page : 394 pages
File Size : 53,7 Mb
Release : 1987
Category : Cell death
ISBN : UCAL:B4311495

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Perspectives on Mammalian Cell Death by C. S. Potten Pdf

This volume covers the wide range of approaches to and definitions of cell death as explored by scientists in different disciplines. There is no single definition of cell death that can be accepted and used by all biologists, yet it is clear that understanding how and why cells die is crucial to understanding many biological and pathological processes. The thirteen chapters, written by scientists involved in various disciplines, bring together the experimental approaches and most up-to-date concepts important to different biological disciplines, providing an insight into the common ground and fundamental principles.

Author : Daulat Tulsiani
Publisher : Springer Science & Business Media
Page : 405 pages
File Size : 48,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461502739

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Introduction to Mammalian Reproduction by Daulat Tulsiani Pdf

Introduction to Mammalian Reproduction is a welcome contribution to the fields of gametogenesis, gamete transport, fertilization, and reproduction technologies. Key topics covered include: *formation and maturation of male gametes; *morphology and physiology of female gametes; *how the sperm meets the egg; *sperm-egg fusion, egg activation, and implantation of fertilized egg; *assisted reproduction and environmental chemicals that have an effect on formation and function of male and female gametes. This book is for both researchers and students involved in reproductive biology.

Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Publisher : Springer
Page : 330 pages
File Size : 52,5 Mb
Release : 2015-10-13
Category : Science
ISBN : 9784431556510

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Innovative Medicine by Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto Pdf

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Author : Robert C. King
Publisher : Unknown
Page : 252 pages
File Size : 43,6 Mb
Release : 1970
Category : Nature
ISBN : UOM:39015005815447

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Ovarian Development in Drosophila Melanogaster by Robert C. King Pdf

Author : Jacques Donnez,S. Samuel Kim
Publisher : Cambridge University Press
Page : 569 pages
File Size : 53,7 Mb
Release : 2011-02-03
Category : Medical
ISBN : 9781139496124

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Principles and Practice of Fertility Preservation by Jacques Donnez,S. Samuel Kim Pdf

The specialty of fertility preservation offers patients with cancer, who are rendered infertile by chemo- and radiotherapy, the opportunity to realize their reproductive potential. This gold-standard publication defines the specialty. The full range of techniques and scientific concepts is covered in detail, and the author team includes many of the world's leading experts in the field. The book opens with introductions to fertility preservation in both cancer and non-cancer patients, followed by cancer biology, epidemiology and treatment, and reproductive biology and cryobiology. Subsequent sections cover fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of both ovarian tissue and the whole ovary, and in-vitro follicle growth and maturation. Concluding chapters address future technologies, as well as ethical, legal and religious issues. Richly illustrated throughout, this is a key resource for all clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.

Author : David H. Evans,James B. Claiborne
Publisher : CRC Press
Page : 552 pages
File Size : 43,6 Mb
Release : 1997-10-10
Category : Science
ISBN : 0849384273

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The Physiology of Fishes, Second Edition by David H. Evans,James B. Claiborne Pdf

As in the bestselling first edition, The Physiology of Fishes, Second Edition is a comprehensive, state-of-the-art review of the major areas of research in modern fish physiology. This Second Edition is entirely revised, with 17 of the 18 chapters written by new authors. It also includes four entirely new chapters:

Author : Ahmed R. G.
Publisher : BoD – Books on Demand
Page : 158 pages
File Size : 40,5 Mb
Release : 2018-01-31
Category : Medical
ISBN : 9789535137580

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Germ Cell by Ahmed R. G. Pdf

This book focuses on the development and biology of germ cell and is edited by Ahmed RG, associate professor and Doctor of Developmental and Experimental Biology, Division of Anatomy and Embryology, Zoology Department, Faculty of Science, Beni-Suef University, Egypt. While many articles have appeared in journals on germ cell, this book provides you with a rare treat - an extensive and intensive study on it. It is one of a kind, offering important and valuable information about the biology of germ cell. This book covers the specification, regulation, and reprogramming of germ cell and germ line stem cells. This book provides important information about the new insight into germ cell signaling and the genotoxic in vitro studies in testicular germ cells. This book offers significant results about the origin, specification, and development of the female germ line in placental mammals and the germ cell tumors and their association with pregnancy.

Author : James W. Wilson,Catherine Booth,C. S. Potten
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 40,8 Mb
Release : 1998
Category : Medical
ISBN : 0412838605

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Apoptosis Genes by James W. Wilson,Catherine Booth,C. S. Potten Pdf

This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.

Author : Kevin Coward,Dagan Wells
Publisher : Cambridge University Press
Page : 408 pages
File Size : 54,8 Mb
Release : 2013-10-31
Category : Medical
ISBN : 9781107276253

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Textbook of Clinical Embryology by Kevin Coward,Dagan Wells Pdf

The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.

Author : Peter C. K. Leung,Eli Y. Adashi
Publisher : Academic Press
Page : 625 pages
File Size : 47,7 Mb
Release : 2018-09-10
Category : Medical
ISBN : 9780128132104

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The Ovary by Peter C. K. Leung,Eli Y. Adashi Pdf

The Ovary, Third Edition, includes more than 60% new material that highlights the clinical aspects of human ovarian functions. It covers advances in the areas of genomics, assisted reproductive technology, and cancer diagnosis and treatment. This updated edition synthesizes new information at the molecular, cellular and organismal levels, while also presenting modern ovarian physiology in a more understandable and comparative context. The book looks at ovarian function from a detailed molecular and cellular level that examines all phases of the ovarian lifecycle that places special emphasis on the pathophysiology of the human ovary, including ovarian carcinogenesis. Represents an unparalleled compilation of chapters that are relevant to contemporary ovarian physiology Provides basic and clinical research on ovarian function, abnormalities, assisted reproductive technology, and cancer Highlights contemporary strategies and treatment paradigms in female factor infertility