Innovative Medicine

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Innovative Medicine

Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Innovative Medicine Book PDF

Author : Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Publisher : Springer
Page : 330 pages
File Size : 42,6 Mb
Release : 2015-10-13
Category : Science
ISBN : 9784431556510

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Innovative Medicine by Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto Pdf

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Medical Innovation in the Changing Healthcare Marketplace

National Research Council,Institute of Medicine,Board on Health Care Services,Policy and Global Affairs,Board on Science, Technology, and Economic Policy
Medical Innovation in the Changing Healthcare Marketplace Book PDF

Author : National Research Council,Institute of Medicine,Board on Health Care Services,Policy and Global Affairs,Board on Science, Technology, and Economic Policy
Publisher : National Academies Press
Page : 92 pages
File Size : 40,9 Mb
Release : 2002-05-06
Category : Medical
ISBN : 0309183014

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Medical Innovation in the Changing Healthcare Marketplace by National Research Council,Institute of Medicine,Board on Health Care Services,Policy and Global Affairs,Board on Science, Technology, and Economic Policy Pdf

A wave of new health care innovation and growing demand for health care, coupled with uncertain productivity improvements, could severely challenge efforts to control future health care costs. A committee of the National Research Council and the Institute of Medicine organized a conference to examine key health care trends and their impact on medical innovation. The conference addressed the following question: In an environment of renewed concern about rising health care costs, where can public policy stimulate or remove disincentives to the development, adoption and diffusion of high-value innovation in diagnostics, therapeutics, and devices?

The Changing Economics of Medical Technology

Institute of Medicine,Committee on Technological Innovation in Medicine
The Changing Economics of Medical Technology Book PDF

Author : Institute of Medicine,Committee on Technological Innovation in Medicine
Publisher : National Academies Press
Page : 225 pages
File Size : 40,8 Mb
Release : 1991-02-01
Category : Medical
ISBN : 9780309044912

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The Changing Economics of Medical Technology by Institute of Medicine,Committee on Technological Innovation in Medicine Pdf

Americans praise medical technology for saving lives and improving health. Yet, new technology is often cited as a key factor in skyrocketing medical costs. This volume, second in the Medical Innovation at the Crossroads series, examines how economic incentives for innovation are changing and what that means for the future of health care. Up-to-date with a wide variety of examples and case studies, this book explores how payment, patent, and regulatory policiesâ€"as well as the involvement of numerous government agenciesâ€"affect the introduction and use of new pharmaceuticals, medical devices, and surgical procedures. The volume also includes detailed comparisons of policies and patterns of technological innovation in Western Europe and Japan. This fact-filled and practical book will be of interest to economists, policymakers, health administrators, health care practitioners, and the concerned public.

Innovative Approaches in Drug Discovery

Bhushan Patwardhan,Rathnam Chaguturu
Innovative Approaches in Drug Discovery Book PDF

Author : Bhushan Patwardhan,Rathnam Chaguturu
Publisher : Academic Press
Page : 480 pages
File Size : 44,9 Mb
Release : 2016-10-03
Category : Medical
ISBN : 9780128018224

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Innovative Approaches in Drug Discovery by Bhushan Patwardhan,Rathnam Chaguturu Pdf

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery

German Medical Data Sciences: Shaping Change - Creative Solutions for Innovative Medicine

R. Röhrig,H. Binder,H.-U. Prokosch
German Medical Data Sciences Shaping Change Creative Solutions for Innovative Medicine Book PDF

Author : R. Röhrig,H. Binder,H.-U. Prokosch
Publisher : IOS Press
Page : 330 pages
File Size : 46,6 Mb
Release : 2019-09-25
Category : Medical
ISBN : 9781643680170

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German Medical Data Sciences: Shaping Change - Creative Solutions for Innovative Medicine by R. Röhrig,H. Binder,H.-U. Prokosch Pdf

Healthcare systems have been in a state of flux for a number of years now due to increasing digitalization. Medicine itself is also facing new challenges, and how to maximize the possibilities of artificial intelligence, whether digitalization can help to strengthen patient orientation, and dealing with the issue of data quality and completeness are all issues which require attention, creativity and research. This book presents the proceedings of the 64th annual conference of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS 2019), held in Dortmund, Germany, from 8 - 11 September 2019. The theme of this year’s conference is Shaping Change – Creative Solutions for Innovative Medicine, and the papers presented here focus on active participation in shaping change while ensuring that good scientific practice, evidence and regulation are not lost as a result of innovation. The book is divided into 8 sections: biostatistics; healthcare IT; interoperability - standards, classification, terminology; knowledge engineering and decision support; medical bioinformatics and systems biology; patient centered care; research infrastructure; and sociotechnical systems / usability and evaluation of healthcare IT. The book will be of interest to all those facing the challenges posed by the ongoing revolution in medicine and healthcare.

Medical Innovation

Kevin E. Behrns,Bruce Gingles,Michael Gregory Sarr
Medical Innovation Book PDF

Author : Kevin E. Behrns,Bruce Gingles,Michael Gregory Sarr
Publisher : Academic Press
Page : 286 pages
File Size : 48,7 Mb
Release : 2018-05-24
Category : Science
ISBN : 9780128149270

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Medical Innovation by Kevin E. Behrns,Bruce Gingles,Michael Gregory Sarr Pdf

Medical Innovation: Concept to Commercialization is a practical, step-by-step approach on how to move a novel concept through development to realize a commercially successful product. Real-world experience cases and knowledgeable contributors provide lessons that cover the practices of diverse organizations and multiple products. This important reference will help improve success and avoid innovation failure for translational researchers, entrepreneurs, medical school educators, biomedical engineering students and faculty, and aspiring physicians. Provides multiple considerations and comprehensive lessons from varied organizations, researchers and products Designed to help address topics that improve success and avoid the high cost of innovation failure Recommends the practical steps needed to move a novel, non-developed concept into a tangible, realistic and commercially successful product

You Bet Your Life

Paul A. Offit
You Bet Your Life Book PDF

Author : Paul A. Offit
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2024-05-14
Category : Electronic
ISBN : 154160492X

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You Bet Your Life by Paul A. Offit Pdf

From one of America's top physicians, a "riveting," "fascinating," and "timely" (Nature) history of risk in medicine Every medical decision--whether to have chemotherapy, an X-ray, or surgery--is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the first blood transfusions four hundred years ago to the hunt for a COVID-19 vaccine, risk has been essential to the discovery of new treatments. More importantly, understanding the risks is crucial to whether, as a society or as individuals, we accept them. Told in Offit's vigorous and rigorous style, You Bet Your Life is an entertaining history of medicine. But it also lays bare the tortured relationships between intellectual breakthroughs, political realities, and human foibles. As we have learned from the COVID pandemic--the debates over lockdowns, masks, and vaccines--it's all too easy to get everything wrong. Updated with a new introduction, You Bet Your Life is an essential read for getting the future a bit more right.

Innovative Medical Technology Based on Artificial Cells, Including its Different Configurations

Thomas Ming Swi Chang,Binglan Yu
Innovative Medical Technology Based on Artificial Cells Including its Different Configurations Book PDF

Author : Thomas Ming Swi Chang,Binglan Yu
Publisher : Frontiers Media SA
Page : 148 pages
File Size : 42,7 Mb
Release : 2023-11-28
Category : Medical
ISBN : 9782832540022

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Innovative Medical Technology Based on Artificial Cells, Including its Different Configurations by Thomas Ming Swi Chang,Binglan Yu Pdf

Artificial Cells are not to reproduce biological cells but to prepare an artificial system for possible uses in medicine and other areas. Many of the ideas on artificial cells are being extensively applied and extended by researchers worldwide, resulting in rapid and exciting progress and discoveries. Different configurations include using emulsion methods and microfluidizers to form microscopic or nano dimension cells called artificial cells, synthetic cells, microcapsules, nanocapsules, liposomes, microparticles, nanoparticles, polymersomes, etc. Macro dimensions artificial cells are used for bioencapsulated cells. Soluble nanobiotherapeutics can be formed by crosslinking proteins and enzymes or by PEG conjugation. The principle of artificial cell has now evolved into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation, biosorbent/immunosorbent hemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, COVID_19 vaccine, COVID_19 therapy, nanobiotechnology, nanotechnology and other areas.

Promoting Access to Medical Technologies and Innovation - Intersections between Public Health, Intellectual Property and Trade

World Intellectual Property Organization
Promoting Access to Medical Technologies and Innovation Intersections between Public Health Intellectual Property and Trade Book PDF

Author : World Intellectual Property Organization
Publisher : WIPO
Page : 259 pages
File Size : 42,9 Mb
Release : 2013
Category : Law
ISBN : 9789280523089

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Promoting Access to Medical Technologies and Innovation - Intersections between Public Health, Intellectual Property and Trade by World Intellectual Property Organization Pdf

This study has emerged from an ongoing program of trilateral cooperation between WHO, WTO and WIPO. It responds to an increasing demand, particularly in developing countries, for strengthened capacity for informed policy-making in areas of intersection between health, trade and IP, focusing on access to and innovation of medicines and other medical technologies.

Modern Methods of Clinical Investigation

Institute of Medicine,Committee on Technological Innovation in Medicine
Modern Methods of Clinical Investigation Book PDF

Author : Institute of Medicine,Committee on Technological Innovation in Medicine
Publisher : National Academies Press
Page : 241 pages
File Size : 41,7 Mb
Release : 1990-02-01
Category : Medical
ISBN : 9780309042864

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Modern Methods of Clinical Investigation by Institute of Medicine,Committee on Technological Innovation in Medicine Pdf

The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.

Drugs Looking for Diseases

R. Vos
Drugs Looking for Diseases Book PDF

Author : R. Vos
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 47,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401137966

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Drugs Looking for Diseases by R. Vos Pdf

We all know how much time, effort and money it takes to develop a new drug. Hundreds of chemical compounds have to be synthesized and thousands of different activities in biology, physiology, pharmacology, clinical investigation, management and marketing have to be initiated and coordinated. Each new drug starts a voyage of discovery through an unmapped terrain which is shrouded in mist and beset by pitfalls, as Dr. Rein Vos puts it in his absorbing inside story of the development of the beta-adrenoceptor blocking agents and the calcium antagonists. Indeed we know, for example, how long it took before the theory of Ahlquist of the alpha and beta adrenergic receptors was widely accepted. Similarly, it suffices to memorize shortly the difficulty of expanding the new concept of calcium antagonism through the national German boundaries into the world. This shows how laborious and complex pharmaceutical progress is, and we all will benefit from a deeper understanding of the process of innovative drug research.

Advancing Nuclear Medicine Through Innovation

National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine
Advancing Nuclear Medicine Through Innovation Book PDF

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine
Publisher : National Academies Press
Page : 173 pages
File Size : 55,5 Mb
Release : 2007-09-11
Category : Medical
ISBN : 9780309134156

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Advancing Nuclear Medicine Through Innovation by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine Pdf

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Innovative Approaches for Nanobiotechnology in Healthcare Systems

Amna, Touseef,Hassan, M. Shamshi
Innovative Approaches for Nanobiotechnology in Healthcare Systems Book PDF

Author : Amna, Touseef,Hassan, M. Shamshi
Publisher : IGI Global
Page : 424 pages
File Size : 53,8 Mb
Release : 2021-09-17
Category : Technology & Engineering
ISBN : 9781799882527

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Innovative Approaches for Nanobiotechnology in Healthcare Systems by Amna, Touseef,Hassan, M. Shamshi Pdf

Innovative and fusion technologies have shown an incredible ability to improve various aspects of society, such as healthcare systems. Nanobiotechnology is one such technology that is being applied to medical equipment and treatment approaches. Many pharmaceutical and medical companies have begun to count on medical nanotechnology due to its abundant applications and practical uses. Innovative Approaches for Nanobiotechnology in Healthcare Systems is a pivotal reference source that provides insights into a comprehensive collection of novel techniques used for the development of safe drugs using the available resources for diverse deadly diseases. This book discusses the various platforms of nanobiotechnology that are utilized in various fields. It is expected that bionanosytems will play a crucial role in the treatment of human diseases and the improvement of existing healthcare systems. This book is ideal for scientists, biotechnologists, microbiologists, medical professionals, entrepreneurs, policymakers, researchers, academicians, and students.

Ecohealth Research in Practice

Dominique F. Charron
Ecohealth Research in Practice Book PDF

Author : Dominique F. Charron
Publisher : Springer Science & Business Media
Page : 282 pages
File Size : 52,9 Mb
Release : 2011-11-25
Category : Medical
ISBN : 1461405173

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Ecohealth Research in Practice by Dominique F. Charron Pdf

This book is about doing innovative research to achieve sustainable and equitable change in people’s health and well-being through improved interactions with the environment. It presents experiences from the field of ecosystem approaches to health (or ecohealth research) and some insights and lessons learned. It builds on previous literature, notably Forget (1997), Forget and Lebel (2001), Lebel (2003), and Waltner-Toews et al. (2008). Through case-studies and other contributions by researchers supported by Canada’s International Development Research Centre (IDRC), the book presents evidence of real changes in conditions of people, their health, and the ecosystems that support them. These changes were derived from applications of an ecosystem approach to health in developing regions of the world. The book also illustrates the resulting body of applied, participatory, and action research that improved health and environmental management in developing countries and, in many cases, influenced policies and practices.

New Drugs, Fair Prices

Brian D. Smith
New Drugs Fair Prices Book PDF

Author : Brian D. Smith
Publisher : Taylor & Francis
Page : 285 pages
File Size : 53,5 Mb
Release : 2022-11-21
Category : Business & Economics
ISBN : 9781000781298

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New Drugs, Fair Prices by Brian D. Smith Pdf

New Drugs, Fair Prices addresses the important question of how we might get the innovative new medicines we need at prices we can afford. Today, this debate is impassioned but sterile. One side calls for price controls, discounting their impact on investment in innovation. The other points to miraculous new therapies, disregarding their affordability and social inequity. This polarized argument creates more heat than light, threatening the social contract between the industry and society on which pharmaceutical innovation depends. This ground-breaking book takes a wholly new perspective on the issue and raises the debate to a more informed and productive level. Drawing on interviews with more than 70 experts across the pharmaceutical innovation world and combining a diverse literature from scientific, political, economic and business domains, it describes how a sustainable and affordable supply of new medicines is possible only by balancing pharmaceutical innovation’s complex, adaptive ecosystem. By considering how each of the ecosystem’s seven habitats work and interact with the others, it makes a comprehensive set of recommendations for achieving that ecosystem balance. The core message of New Drugs, Fair Prices is important to anyone who ever has needed or will ever need a medicine: we can have a sustainable supply of new medicines that are both innovative and affordable if we manage the pharmaceutical innovation ecosystem intelligently.