Cellular And Molecular Aspects Of Myeloproliferative Neoplasms Part A

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A

Anonim
Cellular and Molecular Aspects of Myeloproliferative Neoplasms Part A Book PDF

Author : Anonim
Publisher : Academic Press
Page : 0 pages
File Size : 53,9 Mb
Release : 2021-10-21
Category : Science
ISBN : 0323899390

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B

Anonim
Cellular and Molecular Aspects of Myeloproliferative Neoplasms Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 242 pages
File Size : 50,5 Mb
Release : 2022-02-11
Category : Science
ISBN : 9780323899420

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B, Volume 366 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections cover Genetic and Sex predisposition to MPN, Transcriptional configurations of Myeloproliferative Neoplasms, Inhibitors and therapeutic targets of MPN, Mutational landscape of blast-phase myeloproliferative neoplasm (MPN-BP) and antecedent MPN, and Lessons from Mouse model of MPN, Lab tests for MPN. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists from international sources Offers a wide range of perspectives on specific subjects

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A

Anonim
Cellular and Molecular Aspects of Myeloproliferative Neoplasms Part A Book PDF

Author : Anonim
Publisher : Academic Press
Page : 248 pages
File Size : 47,9 Mb
Release : 2021-10-29
Category : Science
ISBN : 9780323899406

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists and drawn from international sources Offers a wide range of perspectives on specific subjects

Myeloproliferative Neoplasms

Tiziano Barbui,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Tiziano Barbui,Ayalew Tefferi
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 45,7 Mb
Release : 2012-02-03
Category : Medical
ISBN : 9783642249884

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Myeloproliferative Neoplasms by Tiziano Barbui,Ayalew Tefferi Pdf

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Molecular Aspects of Hematologic Malignancies

Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski
Molecular Aspects of Hematologic Malignancies Book PDF

Author : Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski
Publisher : Springer Science & Business Media
Page : 468 pages
File Size : 46,7 Mb
Release : 2012-06-30
Category : Science
ISBN : 9783642294679

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Molecular Aspects of Hematologic Malignancies by Michal Witt,Malgorzata Dawidowska,Tomasz Szczepanski Pdf

This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.

Molecular and Cellular Changes in the Cancer Cell

Anonim
Molecular and Cellular Changes in the Cancer Cell Book PDF

Author : Anonim
Publisher : Academic Press
Page : 616 pages
File Size : 45,7 Mb
Release : 2016-11-16
Category : Science
ISBN : 9780128096031

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Molecular and Cellular Changes in the Cancer Cell by Anonim Pdf

Molecular and Cellular Changes in the Cancer Cell,the latest volume in the Progress in Molecular Biology and Translational Science series, includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. This volume examines some of the latest advances, highlighting some of the most important molecular and cellular alterations and environmental influences that collectively cause a normal cell to become cancerous. Special emphasis is given to changes that take place at the molecular and cellular level. Comprehensive and up-to-date survey of current knowledge on the cancer cell Includes the latest advances and the most important molecular and cellular alterations and environmental influences collectively causing cells to become cancerous Written by leading experts in the field

Chronic Myeloproliferative Disorders

Tariq Mughal,John M. Goldman
Chronic Myeloproliferative Disorders Book PDF

Author : Tariq Mughal,John M. Goldman
Publisher : CRC Press
Page : 0 pages
File Size : 55,5 Mb
Release : 2008-08-27
Category : Medical
ISBN : 0415415985

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Chronic Myeloproliferative Disorders by Tariq Mughal,John M. Goldman Pdf

With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.

Managing Myeloproliferative Neoplasms

Ruben A. Mesa,Claire N. Harrison
Managing Myeloproliferative Neoplasms Book PDF

Author : Ruben A. Mesa,Claire N. Harrison
Publisher : Cambridge University Press
Page : 207 pages
File Size : 54,5 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781316033777

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Managing Myeloproliferative Neoplasms by Ruben A. Mesa,Claire N. Harrison Pdf

This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.

Bone Marrow Biopsy Pathology

Christine Beham-Schmid,Annette Schmitt-Graeff
Bone Marrow Biopsy Pathology Book PDF

Author : Christine Beham-Schmid,Annette Schmitt-Graeff
Publisher : Springer Nature
Page : 533 pages
File Size : 42,9 Mb
Release : 2020-08-05
Category : Medical
ISBN : 9783662603093

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Bone Marrow Biopsy Pathology by Christine Beham-Schmid,Annette Schmitt-Graeff Pdf

This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.

Biology and Treatment of Leukemia and Bone Marrow Neoplasms

Vinod Pullarkat,Guido Marcucci
Biology and Treatment of Leukemia and Bone Marrow Neoplasms Book PDF

Author : Vinod Pullarkat,Guido Marcucci
Publisher : Springer Nature
Page : 200 pages
File Size : 43,8 Mb
Release : 2021-10-09
Category : Medical
ISBN : 9783030783112

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Biology and Treatment of Leukemia and Bone Marrow Neoplasms by Vinod Pullarkat,Guido Marcucci Pdf

This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.

Cancer Cytogenetics

Sverre Heim,Felix Mitelman
Cancer Cytogenetics Book PDF

Author : Sverre Heim,Felix Mitelman
Publisher : John Wiley & Sons
Page : 642 pages
File Size : 41,8 Mb
Release : 2015-08-17
Category : Medical
ISBN : 9781118795538

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Cancer Cytogenetics by Sverre Heim,Felix Mitelman Pdf

The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible

Dacie and Lewis Practical Haematology E-Book

Barbara J. Bain,Imelda Bates,Mike A Laffan
Dacie and Lewis Practical Haematology E Book Book PDF

Author : Barbara J. Bain,Imelda Bates,Mike A Laffan
Publisher : Elsevier Health Sciences
Page : 600 pages
File Size : 52,5 Mb
Release : 2016-08-11
Category : Medical
ISBN : 9780702069253

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Dacie and Lewis Practical Haematology E-Book by Barbara J. Bain,Imelda Bates,Mike A Laffan Pdf

For more than 65 years, this best-selling text by Drs. Barbara J. Bain, Imelda Bates, and Mike A. Laffan has been the worldwide standard in laboratory haematology. The 12th Edition of Dacie and Lewis Practical Haematology continues the tradition of excellence with thorough coverage of all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as traditional manual methods of measurement. You’ll find expert discussions of the principles of each test, possible causes of error, and the interpretation and clinical significance of the findings. A unique section on haematology in under-resourced laboratories. Ideal as a laboratory reference or as a comprehensive exam study tool. Each templated, easy-to-follow chapter has been completely updated, featuring new information on haematological diagnosis, molecular testing, blood transfusion- and much more. Complete coverage of the latest advances in the field. An expanded section on coagulation now covers testing for new anticoagulants and includes clinical applications of the tests.

Methods in Stem Cell Biology - Part B

Anonim
Methods in Stem Cell Biology Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 262 pages
File Size : 53,6 Mb
Release : 2022-08-09
Category : Science
ISBN : 9780323900195

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Methods in Stem Cell Biology - Part B by Anonim Pdf

Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Cell Biology series Includes the latest information on the topic of Methods in Cancer Stem Cell Biology

Oxford Specialist Handbook: Myeloproliferative Neoplasms

Tariq I. Mughal,Tiziano Barbui
Oxford Specialist Handbook Myeloproliferative Neoplasms Book PDF

Author : Tariq I. Mughal,Tiziano Barbui
Publisher : Oxford University Press, USA
Page : 361 pages
File Size : 44,5 Mb
Release : 2020-08-06
Category : Medical
ISBN : 9780198744214

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Oxford Specialist Handbook: Myeloproliferative Neoplasms by Tariq I. Mughal,Tiziano Barbui Pdf

Our understanding of myeloproliferative neoplasms (MPN) disorders has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structure to facilitate learning specialist information presenting core information in 'bite size' chunks.

Atlas of Diagnostic Hematology

Mohamed E. Salama
Atlas of Diagnostic Hematology Book PDF

Author : Mohamed E. Salama
Publisher : Elsevier Health Sciences
Page : 415 pages
File Size : 55,8 Mb
Release : 2020-09-01
Category : Medical
ISBN : 9780323567343

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Atlas of Diagnostic Hematology by Mohamed E. Salama Pdf

Ideal as a quick, easy-to-use reference in the laboratory or clinical setting, Atlas of Diagnostic Hematology is an abundantly illustrated guide to the vast range of malignant and non-malignant disorders of the blood. More than 1,200 vibrant, full-color images enable you to identify and compare the unique clinical and histologic features of various blood disorders and confidently reach a diagnosis. Coverage includes photos of actual cases that span the entire range of this complex field, including rare conditions and difficult diagnoses. Features more than 1,200 images including full-color pathologic and clinical images covering a wide range of hematologic malignant and non-malignant conditions. Covers a range of disease stages, from the slightest indication where diagnosis can be complicated or missed entirely, to what the average blood or biopsy sample signifying disease may look like, to an advanced stage where disease indications are abundantly clear. Helps you distinguish between similar and overlapping features and symptoms to arrive at an accurate diagnosis. Provides up-to-date information on infectious processes in blood and bone marrow, classification system of myeloid neoplasms, and indolent and aggressive mature T and NK-cell lymphomas. Includes diagnostic algorithms with differential diagnoses for conditions with similar histologic features and clinical symptoms. Contains the latest WHO classifications for pathologic, genetic, and clinical information.