Myeloproliferative Neoplasms

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Fast Facts: Myeloproliferative Neoplasms

R.A. Mesa,C.N. Harrison
Fast Facts Myeloproliferative Neoplasms Book PDF

Author : R.A. Mesa,C.N. Harrison
Publisher : Karger Medical and Scientific Publishers
Page : 117 pages
File Size : 52,6 Mb
Release : 2019-02-11
Category : Medical
ISBN : 9781910797808

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Fast Facts: Myeloproliferative Neoplasms by R.A. Mesa,C.N. Harrison Pdf

Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Managing Myeloproliferative Neoplasms

Ruben A. Mesa,Claire N. Harrison
Managing Myeloproliferative Neoplasms Book PDF

Author : Ruben A. Mesa,Claire N. Harrison
Publisher : Cambridge University Press
Page : 207 pages
File Size : 40,7 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781316033777

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Managing Myeloproliferative Neoplasms by Ruben A. Mesa,Claire N. Harrison Pdf

This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.

Myeloproliferative Neoplasms

Tiziano Barbui,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Tiziano Barbui,Ayalew Tefferi
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 47,7 Mb
Release : 2012-02-03
Category : Medical
ISBN : 9783642249884

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Myeloproliferative Neoplasms by Tiziano Barbui,Ayalew Tefferi Pdf

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Myeloproliferative Neoplasms

Tiziano Barbui,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Tiziano Barbui,Ayalew Tefferi
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 43,6 Mb
Release : 2012-01-10
Category : Medical
ISBN : 9783642249891

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Myeloproliferative Neoplasms by Tiziano Barbui,Ayalew Tefferi Pdf

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Oxford Specialist Handbook: Myeloproliferative Neoplasms

Tariq I. Mughal,Tiziano Barbui
Oxford Specialist Handbook Myeloproliferative Neoplasms Book PDF

Author : Tariq I. Mughal,Tiziano Barbui
Publisher : Oxford University Press, USA
Page : 361 pages
File Size : 45,5 Mb
Release : 2020-08-06
Category : Medical
ISBN : 9780198744214

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Oxford Specialist Handbook: Myeloproliferative Neoplasms by Tariq I. Mughal,Tiziano Barbui Pdf

Our understanding of myeloproliferative neoplasms (MPN) disorders has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structure to facilitate learning specialist information presenting core information in 'bite size' chunks.

Fast Facts: Myeloproliferative Neoplasms

Ruben A. Mesa,Claire N. Harrison
Fast Facts Myeloproliferative Neoplasms Book PDF

Author : Ruben A. Mesa,Claire N. Harrison
Publisher : Karger Medical and Scientific Publishers
Page : 117 pages
File Size : 43,6 Mb
Release : 2019
Category : Medical
ISBN : 9781910797792

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Fast Facts: Myeloproliferative Neoplasms by Ruben A. Mesa,Claire N. Harrison Pdf

Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: * Essential thrombocythemia (ET) - characterized by increased platelet count * Polycythemia vera (PV) - characterized by excessive production of red blood cells * Primary myelofibrosis - a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Myeloproliferative Neoplasms

Srdan Verstovsek,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Srdan Verstovsek,Ayalew Tefferi
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 54,6 Mb
Release : 2010-10-17
Category : Medical
ISBN : 9781607612667

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Myeloproliferative Neoplasms by Srdan Verstovsek,Ayalew Tefferi Pdf

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

Chronic Myeloproliferative Disorders

Tariq Mughal,John M. Goldman
Chronic Myeloproliferative Disorders Book PDF

Author : Tariq Mughal,John M. Goldman
Publisher : CRC Press
Page : 0 pages
File Size : 42,6 Mb
Release : 2008-08-27
Category : Medical
ISBN : 0415415985

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Chronic Myeloproliferative Disorders by Tariq Mughal,John M. Goldman Pdf

With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.

Managing Myeloproliferative Neoplasms

Ruben A. Mesa,Claire N. Harrison
Managing Myeloproliferative Neoplasms Book PDF

Author : Ruben A. Mesa,Claire N. Harrison
Publisher : Cambridge University Press
Page : 207 pages
File Size : 44,6 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107444430

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Managing Myeloproliferative Neoplasms by Ruben A. Mesa,Claire N. Harrison Pdf

Provides clear, broad and comprehensive guidance across common and rare MPNs for both day-to-day management and special situations.

Myeloproliferative Neoplasms

Tiziano Barbui,Ayalew Tefferi
Myeloproliferative Neoplasms Book PDF

Author : Tiziano Barbui,Ayalew Tefferi
Publisher : Springer
Page : 240 pages
File Size : 53,7 Mb
Release : 2016-08-23
Category : Medical
ISBN : 3662520273

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Myeloproliferative Neoplasms by Tiziano Barbui,Ayalew Tefferi Pdf

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B

Anonim
Cellular and Molecular Aspects of Myeloproliferative Neoplasms Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 242 pages
File Size : 40,9 Mb
Release : 2022-02-11
Category : Science
ISBN : 9780323899420

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part B, Volume 366 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections cover Genetic and Sex predisposition to MPN, Transcriptional configurations of Myeloproliferative Neoplasms, Inhibitors and therapeutic targets of MPN, Mutational landscape of blast-phase myeloproliferative neoplasm (MPN-BP) and antecedent MPN, and Lessons from Mouse model of MPN, Lab tests for MPN. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists from international sources Offers a wide range of perspectives on specific subjects

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A

Anonim
Cellular and Molecular Aspects of Myeloproliferative Neoplasms Part A Book PDF

Author : Anonim
Publisher : Academic Press
Page : 248 pages
File Size : 54,8 Mb
Release : 2021-10-29
Category : Science
ISBN : 9780323899406

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Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A by Anonim Pdf

Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology. Chapters in this new release include MPN a continuum of different disease entities, Bone marrow microenvironment of MPN, Extramedullary hemopoiesis in MPN, The JAK2 mutation, Calreticulin mutations in myeloproliferative neoplasms, and Cytogenetic abnormalities and non-driver mutations in MPN. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists and drawn from international sources Offers a wide range of perspectives on specific subjects

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

John Mascarenhas,Ronald Hoffman,Ross Levine,Raajit Rampal
Myeloproliferative Neoplasms An Issue of Hematology Oncology Clinics of North America Book PDF

Author : John Mascarenhas,Ronald Hoffman,Ross Levine,Raajit Rampal
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 48,7 Mb
Release : 2021-02-27
Category : Medical
ISBN : 9780323795890

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Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America by John Mascarenhas,Ronald Hoffman,Ross Levine,Raajit Rampal Pdf

This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.

Myeloproliferative Disorders

Anthony M. Camden
Myeloproliferative Disorders Book PDF

Author : Anthony M. Camden
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 41,8 Mb
Release : 2014
Category : Myeloproliferative disorders
ISBN : 1633212017

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Myeloproliferative Disorders by Anthony M. Camden Pdf

Myeloproliferative disorders are a group of clonal haematological neoplasms characterised by proliferation of one or more cells of myeloid lineage. They are the result of acquired mutations in the progenitor cell leading to hyper proliferation or neoplastic expansion of more mature forms of myeloid cells. Cells retain their functional ability with some degree of defects and also lead to suppression of normal stem cells. The most common type of Myeloproliferative Neoplasms (MPN) can broadly be classified into BCR ABL positive (Chronic Myelogenous Leukemia) and BCR ABL negative Disorders (Polycythemia Vera PV, Essential Thrombocytosis ET and Primary Myelofibrosis PMF). There are other rare types which have relatively low incidence like chronic neutrophilic leukemia, chronic eosinophilic leukemia, systemic mastocytosis and myeloproliferative neoplasms unclassifiable. These are the indolent type of haematological malignancies associated with marrow hypercellularity and organomegaly, with gradual progression to myelofibrosis or transformation to acute leukemias. During the dormant course of the BCR ABL negative MPN, they are more prone to thrombo-hemorrhagic complications and the treatment strategy is directed mostly to prevent complications. The past decade; therapies for BCR ABL positive disease (CML) have been a milestone achievement in keeping the disease in remission for many years, preventing major complications and halting the progression of the disease. This book discusses the classification, diagnosis and treatment of myeloproliferative diseases and provides insight on the symptoms and risk factors involved in the diseases.

Bone Marrow Biopsy Pathology

Christine Beham-Schmid,Annette Schmitt-Graeff
Bone Marrow Biopsy Pathology Book PDF

Author : Christine Beham-Schmid,Annette Schmitt-Graeff
Publisher : Springer Nature
Page : 533 pages
File Size : 46,7 Mb
Release : 2020-08-05
Category : Medical
ISBN : 9783662603093

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Bone Marrow Biopsy Pathology by Christine Beham-Schmid,Annette Schmitt-Graeff Pdf

This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.