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Author : Syed F. Ali
Publisher : Unknown
Page : 128 pages
File Size : 42,5 Mb
Release : 1996
Category : Electronic
ISBN : OCLC:1068786117
Author : Syed F. Ali
Publisher : Unknown
Page : 234 pages
File Size : 49,9 Mb
Release : 1995
Category : Electronic
ISBN : OCLC:34903401
Author : Syed F. Ali
Publisher : Unknown
Page : 128 pages
File Size : 51,7 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:757449620
Author : Syed F. Ali,Yasuo Takahashi
Publisher : Unknown
Page : 128 pages
File Size : 46,5 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:757476868
Author : Syed F. Ali,Toshitaka Nabeshima,Tomoji Yanagita
Publisher : Unknown
Page : 642 pages
File Size : 44,9 Mb
Release : 2004
Category : Science
ISBN : 1573315230
Author : Sherrel Howard
Publisher : John Wiley & Sons
Page : 208 pages
File Size : 43,9 Mb
Release : 2014-02-27
Category : Medical
ISBN : 9781118850145
Drug abuse has been, and continues to be, a global societalissue with diverse sets of impacts. Drugs of Abuse: Pharmacologyand Molecular Mechanisms introduces the basic principles ofpharmacology and neuroscience of drug abuse. Understanding thechemistry of commonly abused drugs and their impact on brainfunction will provide students and researchers with a more profoundunderstanding of the molecular basis of drug abuse andaddiction. Drugs of Abuse: Pharmacology and Molecular Mechanismsopens with a brief history of drug use and abuse. Subsequentsections look at specific families of drugs, including stimulants,depressants, and hallucinogens among others, and explore how theirchemical make-up interacts with brain function. The final chapterprovides a brief overview of clinical substance abusetreatment. Providing a concise, accessible introductory overview of thetopic, Drugs of Abuse: Pharmacology and Molecular Mechanismswill be a valuable resource for students, researchers, and othersinterested in how drugs interact with the brain. Introduces readers to the basic principles of neuroscience andpharmacology as related to drug use and abuse. Explores how the chemical make-up of drugs interact with thebrain and can lead to addiction Includes coverage of a wide array of commonly abused familiesof drugs, including stimulants, depressants, hallucinogens, andothers. Provides an essential introduction to the chemical andmolecular underpinnings of drug use and abuse
Author : Sherrel G. Howard
Publisher : Unknown
Page : 210 pages
File Size : 53,6 Mb
Release : 2014
Category : Central nervous system stimulants
ISBN : 1118850041
Drug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience of drug abuse. Understanding the chemistry of commonly abused drugs and their impact on brain function will provide students and researchers with a more profound understanding of the molecular basis of drug abuse and addiction. Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse.
Author : Syed F. Ali
Publisher : Unknown
Page : 0 pages
File Size : 41,5 Mb
Release : 2000
Category : Amphetamine abuse
ISBN : 1573312800
Containing reviewed versions of papers presented at the satellite meeting of the 17th biennial meeting of the International Society for Neurochemistry and the European Society for Neurochemistry held in August 1999, this volume explores the cellular and molecular mechanisms of drugs of abuse, such a
Author : Syed F. Ali
Publisher : Unknown
Page : 362 pages
File Size : 52,5 Mb
Release : 1998
Category : Medical
ISBN : 1573311464
Contains 34 papers from a 1997 meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, convened in Hamilton, Bermuda, clarifying cellular and molecular mechanisms of abused drugs and of pharmacotherapies for drug addition. Papers are organized in sections on gene expression and molecular mechanisms of drug addiction, drugs of abuse and medication development (cocaine and ibogaine), the role of free radicals in drug- induced neurotoxicity, specific neuronal markers in substituted amphetamine-induced toxicity, and prenatal exposure and outcome. Annotation copyrighted by Book News, Inc., Portland, OR
Author : Mary Torregrossa
Publisher : Academic Press
Page : 306 pages
File Size : 52,6 Mb
Release : 2018-08-24
Category : Medical
ISBN : 9780128123317
Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms
Author : Institute of Medicine,Committee on Opportunities in Drug Abuse Research
Publisher : National Academies Press
Page : 330 pages
File Size : 45,8 Mb
Release : 1996-11-01
Category : Medical
ISBN : 9780309055338
Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
Author : R. Pochet,Rosario Donato,J. Haiech,Claus W. Heizmann,Volker Gerke
Publisher : Springer Science & Business Media
Page : 746 pages
File Size : 44,6 Mb
Release : 2011-06-28
Category : Medical
ISBN : 9789401006880
The enormous and varied role of calcium in living systems is now widely appreciated by both cell biologists and clinicians. The identification and characterisation of new calcium binding proteins and regulatory pathways is matched by the recognition of the involvement of calcium binding proteins in a growing number of disease states. This book is intended to introduce clinicians to fundamental biological research, whilst at the same time attracting researchers to the clinical world. The publication of the book coincides with the elucidation of the complete Human Genomic Sequence. As a result of this, scientists now have access to an unprecedented array of data, from which new calcium binding proteins and hence new regulatory pathways will undoubtedly be discovered. It is a further aim of this book to provide a `key' to open the door to the new postgenomic era. The book is in three parts. The first section introduces the reader to the role of calcium in cell biology, providing an appreciation of how this small, simple, non-metabolisable agent can move rapidly and silently through the different cellular compartments, thereby influencing and controlling the fate of the cell. This section also illustrates and dissects the often-complex interplay between calcium and numerous agents in muscle and endocrine cells, neurons, hepatocytes, and platelets. In the second section the reader will discover the role of calcium and its partners in common diseases such as migraine and drug dependence. New classes of diseases such as annexinopathies, channelopathies, calcium-sensing disorders, and citrullinemia are discussed, and the authors give many new insights into the molecular mechanisms of the diseases, thereby explaining how and why they occur. Such information is clearly of primary importance for the pharmaceutical industry. New ideas and concepts of neurodegenerative diseases are introduced, which should stimulate new approaches. Clinicians will also have access, in a comprehensive and authoritative yet highly readable chapter, to data from recent large-scale clinical studies on the numerous and widely prescribed calcium antagonists. The final section gives information on new methods and devices for calcium imaging, and illustrates how calcium movement and change can be monitored and ingeniously utilised as a fast, cheap, and accurate drug screening instrument.
Author : George F. Koob,Michael A. Arends,Michel Le Moal
Publisher : Academic Press
Page : 351 pages
File Size : 51,9 Mb
Release : 2014-07-12
Category : Medical
ISBN : 9780123869593
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction
Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 49,9 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Author : George F. Koob,Michel Le Moal
Publisher : Elsevier
Page : 503 pages
File Size : 51,8 Mb
Release : 2005-11-11
Category : Psychology
ISBN : 9780080497372
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching
