Cellular And Molecular Mechanisms Of Neurotrophin Function In The Nervous System

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Cellular and Molecular Mechanisms of Neurotrophin Function in the Nervous System

Author : Pedro Bekinschtein,Oliver von Bohlen und Halbach
Publisher : Frontiers Media SA
Page : 104 pages
File Size : 51,9 Mb
Release : 2020-06-15
Category : Electronic
ISBN : 9782889637874

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Cellular and Molecular Mechanisms of Neurotrophin Function in the Nervous System by Pedro Bekinschtein,Oliver von Bohlen und Halbach Pdf

Neural Cell Specification

Author : Bernhard H.J. Juurlink,Patrick H. Krone,William M. Kulyk,Valerie M.K. Verge,J. Ronald Doucette
Publisher : Springer Science & Business Media
Page : 311 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461519294

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Neural Cell Specification by Bernhard H.J. Juurlink,Patrick H. Krone,William M. Kulyk,Valerie M.K. Verge,J. Ronald Doucette Pdf

The last decades have witnessed a radical change in our views on central nervous system damage and repair. This change is not only due to the emergence of new powerful tools for the analysis of the brain and its reactions to insults, but it also reflects a conceptual change in the way we approach these problems. As an illustration to this development, it is instructive to go back to the proceedings of a meeting at the NIH in 1955 edited by William F. Windle, which summarizes the disillusioned and pessimistic view on CNS regeneration prevailing at the time. While this generation of researchers were well aware of the issues at stake, they felt they had reached the end of the road; the approaches they had pursued had got stuck and the tools available could not take them any further. I can very well imagine that the participants, most of them leaders in the field, left that conference feeling they had heard their field being sentenced to death.

The Neuron

Author : Irwin B. Levitan,Leonard K. Kaczmarek
Publisher : Oxford University Press, USA
Page : 601 pages
File Size : 44,6 Mb
Release : 2015
Category : Medical
ISBN : 9780199773893

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The Neuron by Irwin B. Levitan,Leonard K. Kaczmarek Pdf

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Cellular and Molecular Biology of Neuronal Development

Author : Ira Black
Publisher : Springer Science & Business Media
Page : 376 pages
File Size : 49,7 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461327172

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Cellular and Molecular Biology of Neuronal Development by Ira Black Pdf

A central problem in neurobiology concerns mechanisms that generate the pro found diversity and specificity of the nervous system. What is the substance of diversification and specificity at the molecular, cellular, and systems levels? 4 How, for example, do 1011 neurons each form approximately 10 interconnec tions, allowing normal physiological function? How does disruption of these processes result in human disease? These proceedings represent the efforts of molecular biologists, embryologists, neurobiologists, and clinicians to approach these issues. in this volume are grouped by subject to present the varieties The chapters of methods used to approach each individual area. Section I deals with embry ogenesis and morphogenesis of the nervous system. In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system. Immunocyto chemical analysis reveals the existence of distinct sUbpopulations within the crest at extremely early stages; cells express neuronal or glial binding patterns at the time of migration. Consequently, interactions with the environment may select for predetermined populations. Le Douarin reaches similar conclusions in Chapter 1 by analyzing migratory pathways and developmental potentials in crest of quail-

Neurotrophic Factors

Author : Stephen D. Skaper
Publisher : Humana Press
Page : 458 pages
File Size : 49,5 Mb
Release : 2018-09-05
Category : Medical
ISBN : 1493985248

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Neurotrophic Factors by Stephen D. Skaper Pdf

This volume collects protocols and procedures utilizing cellular, tissue, and whole animal models that can be applied to the investigation of neurotrophic factors and other agents impacting on these systems. It begins with chapters on the culture of neurons and glia from the central and peripheral nervous systems, neuron-glia and glia-glia co-culture models, oligodendrocytes, and cell-based assays for the evaluation of cell vitality. This revised second edition expands to cover methodology encompassing site-specific direct labeling of neurotrophins and their receptors, angiogenesis assays, stem cells, pancreatic beta-cells, axonal transport, synapse biology, dendritic spine analysis, and brain endothelial cells. Subsequent chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides, as well as protocols describing nanofiber- and nanoparticle-based methods for brain delivery of neurotrophic agents. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Neurotrophic Factors: Methods and Protocols, Second Edition is a valuable resource for a wide audience of readers as they explore nervous system function and pathology.

Neural Plasticity and Memory

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 45,6 Mb
Release : 2007-04-17
Category : Psychology
ISBN : 9781420008418

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Neural Plasticity and Memory by Federico Bermudez-Rattoni Pdf

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Neurobiochemistry

Author : B. Hamprecht,V. Neuhoff
Publisher : Springer Science & Business Media
Page : 221 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642709401

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Neurobiochemistry by B. Hamprecht,V. Neuhoff Pdf

Basic Neurochemistry

Author : George J. Siegel,Bernard W. Agranoff
Publisher : Lippincott Raven
Page : 1216 pages
File Size : 51,5 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015045578211

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Basic Neurochemistry by George J. Siegel,Bernard W. Agranoff Pdf

Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Textbook of Neural Repair and Rehabilitation

Author : Michael E. Selzer,Stephanie Clarke,Leonardo G. Cohen,Gert Kwakkel (Professor),Robert H. Miller (Professor)
Publisher : Cambridge University Press
Page : 693 pages
File Size : 46,7 Mb
Release : 2014
Category : Nervous system
ISBN : 9781107011670

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Textbook of Neural Repair and Rehabilitation by Michael E. Selzer,Stephanie Clarke,Leonardo G. Cohen,Gert Kwakkel (Professor),Robert H. Miller (Professor) Pdf

In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.

The Neuron

Author : Irwin B. Levitan,Leonard K. Kaczmarek
Publisher : Oxford University Press, USA
Page : 640 pages
File Size : 48,7 Mb
Release : 2002
Category : Molecular neurobiology
ISBN : 0195145232

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The Neuron by Irwin B. Levitan,Leonard K. Kaczmarek Pdf

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Hormones, Metabolism and the Benefits of Exercise

Author : Bruce Spiegelman
Publisher : Springer
Page : 108 pages
File Size : 45,5 Mb
Release : 2018-03-07
Category : Science
ISBN : 9783319727905

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Hormones, Metabolism and the Benefits of Exercise by Bruce Spiegelman Pdf

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Translational Pain Research

Author : Lawrence Kruger,Alan R Light
Publisher : CRC Press
Page : 458 pages
File Size : 55,6 Mb
Release : 2009-11-24
Category : Health & Fitness
ISBN : 9781439812105

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Translational Pain Research by Lawrence Kruger,Alan R Light Pdf

One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Molecular mechanisms and pathways in cerebellar function

Author : Catarina Osorio,Lilian Kisiswa,Alanna J. Watt
Publisher : Frontiers Media SA
Page : 175 pages
File Size : 40,9 Mb
Release : 2023-08-21
Category : Science
ISBN : 9782832532195

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Molecular mechanisms and pathways in cerebellar function by Catarina Osorio,Lilian Kisiswa,Alanna J. Watt Pdf

Neurotrophic Factors

Author : Gary R. Lewin,Bruce D. Carter
Publisher : Springer Science & Business Media
Page : 514 pages
File Size : 53,6 Mb
Release : 2014-03-25
Category : Medical
ISBN : 9783642451065

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Neurotrophic Factors by Gary R. Lewin,Bruce D. Carter Pdf

This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.