Neural Plasticity And Memory

Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 40,7 Mb
Release : 2007-04-17
Category : Science
ISBN : 1420008412

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Neural Plasticity and Memory by Federico Bermudez-Rattoni Pdf

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

Author : Catherine Belzung,Peter Wigmore
Publisher : Springer Science & Business Media
Page : 401 pages
File Size : 51,8 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9783642362323

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Neurogenesis and Neural Plasticity by Catherine Belzung,Peter Wigmore Pdf

This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

Author : Sushil K. Jha,Vibha M. Jha
Publisher : Springer
Page : 254 pages
File Size : 40,6 Mb
Release : 2019-02-25
Category : Medical
ISBN : 9789811328145

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Sleep, Memory and Synaptic Plasticity by Sushil K. Jha,Vibha M. Jha Pdf

Over the years there has been growing interest among the scientific community in investigating sleep and how it affects the memory and other brain functions. It is now well established that sleep helps in memory consolidation and induction of neural plasticity, and that short-term deprivation of either total sleep or rapid eye movement sleep alone can induce memory deficits very quickly. Quantitative and qualitative changes in sleep architecture after different training tasks further suggest that discrete memory types may require specific sleep stage/s for optimal memory consolidation, and studies indicate that sleep deprivation alters synaptic plasticity and membrane excitability in the hippocampal neurons and synaptic up-scaling in the cortical neurons. Further, sleep alteration during pregnancy may increase the risk of depression and adversely affect maternal-child relationships, parenting practices, family functioning, and children's development and general wellbeing. This book coherently discusses all these aspects, with a particular focus on the possible role of sleep in memory consolidation and synaptic plasticity. It also highlights the detrimental effects of sleep loss on mental health, the immune system and cognition. This book is a valuable reference resource for students and researchers working in the area of sleep, memory, or neuronal plasticity.

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 50,5 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Page : 195 pages
File Size : 41,8 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309045292

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Discovering the Brain by National Academy of Sciences,Institute of Medicine,Sandra Ackerman Pdf

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author : Peter Meerlo,Ruth M. Benca,Ted Abel
Publisher : Springer
Page : 559 pages
File Size : 52,8 Mb
Release : 2015-05-18
Category : Medical
ISBN : 9783662468784

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Sleep, Neuronal Plasticity and Brain Function by Peter Meerlo,Ruth M. Benca,Ted Abel Pdf

This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question of how sleep and sleep loss ultimately affect cognition and mood. It provides an extensive overview of the latest insights in the role of sleep in regulating gene expression, synaptic plasticity and neurogenesis and how that in turn is linked to learning and memory processes. In addition, readers will learn about the potential clinical implications of insufficient sleep and discover how chronically restricted or disrupted sleep may contribute to age-related cognitive decline and the development of psychiatric disorders such as schizophrenia and depression. The book consists of 19 chapters, written by experts in basic sleep research and sleep medicine, which together cover a wide range of topics on the importance of sleep and consequences of sleep disruption. This book will be of interest to students, researchers and clinicians with a general interest in brain function or a specific interest in sleep.

Author : Helmut L. Haas,György Buzsaki
Publisher : Springer Science & Business Media
Page : 219 pages
File Size : 51,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642732027

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Synaptic Plasticity in the Hippocampus by Helmut L. Haas,György Buzsaki Pdf

This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

Author : Alfredo Meneses
Publisher : Elsevier
Page : 180 pages
File Size : 47,7 Mb
Release : 2013-11-23
Category : Psychology
ISBN : 9780124167117

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Identification of Neural Markers Accompanying Memory by Alfredo Meneses Pdf

Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field. Discusses the alterations of memory in diverse diseases Includes coverage from a basic introduction of memory investigation Reviews brain areas and neurotransmitters involved in memory Discusses behavioral models of memory Contains novel insights into the complexity of signaling and memory Includes the neuropharmacological and neurobiological bases of memory

Author : Ales Stuchlik
Publisher : BoD – Books on Demand
Page : 180 pages
File Size : 48,9 Mb
Release : 2018-07-11
Category : Medical
ISBN : 9781789233568

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The Hippocampus by Ales Stuchlik Pdf

The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

Author : Cosimo Ajmone Marsan,Hansjürgen Matthies
Publisher : Unknown
Page : 696 pages
File Size : 41,6 Mb
Release : 1982
Category : Memory
ISBN : UCAL:B4526022

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Neuronal Plasticity and Memory Formation by Cosimo Ajmone Marsan,Hansjürgen Matthies Pdf

Author : Christian Hansel
Publisher : World Scientific
Page : 193 pages
File Size : 47,7 Mb
Release : 2021-01-04
Category : Medical
ISBN : 9789811228827

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Memory Makes The Brain: The Biological Machinery That Uses Experiences To Shape Individual Brains by Christian Hansel Pdf

The development of the young brain after birth and the emergence of cognitive capacities, mind, and individuality rest on the maturation of a dense net of synaptic connections between neurons. Memory Makes the Brain describes the dramatic, competitive elimination of surplus synapses that occur in the young, maturing brain — in a process called synaptic pruning that was discovered by pediatric neurologist Peter Huttenlocher in the 1970's at the University of Chicago. Explaining similarities between developmental pruning and learning processes in the adult brain, neurobiologist Christian Hansel offers a unique perspective on brain adaptation and plasticity throughout lifetime, at times weaving in personal accounts and memories. The cellular plasticity machinery that enables learning is known to be affected in brain developmental disorders such as autism. Memory Makes the Brain explains how both maturation and adult synaptic plasticity are deregulated in autism, and how we begin to trace back autism-typical behavioral abnormalities to such synaptopathies.

Author : Gianfranco Denes
Publisher : Psychology Press
Page : 198 pages
File Size : 49,6 Mb
Release : 2015-12-14
Category : Psychology
ISBN : 9781317909958

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Neural Plasticity Across the Lifespan by Gianfranco Denes Pdf

Neural Plasticity Across the Lifespan reviews the recent scientific developments which are transforming our understanding of the human brain. For many years it was thought that modifications to the structural and functional organization of the brain were limited to a short early period of life, "the critical period", and, in adults, to the memory system. Recent research suggests that on the contrary we should see the human brain as a flexible structure, which adapts and modifies in response to learning, sensory experience, age and disease. The book provides an integrated overview of contemporary research on neural plasticity - the process by which the brain can change in structure and function to cope with new experiences and react to the effects of acquired damage or sensory deprivation. It reviews data on plasticity in the developing brain, looking at both typical and atypical development, alongside clinical and observational research on the adult population. It covers a number of key topics, including: different forms of neural plasticity factors affecting neural plasticity (ageing and gender), neural plasticity in language acquisition, memory and bodily self-consciousness mechanisms of repair – plasticity following sensory deprivation and acquired brain damage. This is an accessible overview of an emerging field of research which has fundamental implications for how we perceive our potential to change throughout our lives. It will be essential reading for all students of cognitive development, cognitive neuroscience and lifespan development.

Author : Arjen van Ooyen,Markus Butz-Ostendorf
Publisher : Academic Press
Page : 592 pages
File Size : 45,8 Mb
Release : 2017-06-23
Category : Science
ISBN : 9780128038727

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The Rewiring Brain by Arjen van Ooyen,Markus Butz-Ostendorf Pdf

The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage

Author : Joseph I. Tracy,Benjamin M. Hampstead,K. Sathian
Publisher : Oxford University Press, USA
Page : 433 pages
File Size : 41,9 Mb
Release : 2014-12-02
Category : Medical
ISBN : 9780199965243

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Cognitive Plasticity in Neurologic Disorders by Joseph I. Tracy,Benjamin M. Hampstead,K. Sathian Pdf

This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Author : Anonim
Publisher : Academic Press
Page : 576 pages
File Size : 50,6 Mb
Release : 2018-09-01
Category : Medical
ISBN : 9780128120279

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Handbook of in Vivo Neural Plasticity Techniques by Anonim Pdf

Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques. Offers a comprehensive overview of state-of-the-art approaches to studying neuroplasticity in vivo Combines discussions of theoretical underpinnings with the methodological and technical aspects necessary to guarantee success Arranged in a uniform format that clearly and concisely lays out descriptions, methods and the pitfalls of various techniques