Cellular Metabolism And Related Disorders

Author : Jesmine Khan,Po-Shiuan Hsieh
Publisher : BoD – Books on Demand
Page : 230 pages
File Size : 47,8 Mb
Release : 2020-07-15
Category : Science
ISBN : 9781838801816

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Cellular Metabolism and Related Disorders by Jesmine Khan,Po-Shiuan Hsieh Pdf

This book deals with a vital topic: metabolism in the cells of the body and various disorders due to its imbalance and/or diseases that disrupt the metabolism of the body. The objective of this book was to collect and compile up-to-date information from reputed researchers in their respective fields to disseminate the latest information about topics that have profound effects on the metabolic processes in the body including insulin resistance, diabetes mellitus, hypothyroidism, metabolic syndrome, glycogen storage disease, and the urea cycle disorder. In total, there are 12 chapters in this book in which the authors have shared their research findings and real-life experiences in managing their patients.

Author : Shaul Massry
Publisher : Springer Science & Business Media
Page : 611 pages
File Size : 44,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781461342175

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Phosphate Metabolism by Shaul Massry Pdf

We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.

Author : Juliet E. Compston,Jane B. Lian
Publisher : John Wiley & Sons
Page : 559 pages
File Size : 52,5 Mb
Release : 2009-12-22
Category : Science
ISBN : 9780470623985

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Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism by Juliet E. Compston,Jane B. Lian Pdf

EDITOR-IN-CHIEF: Clifford J. Rosen, M.D., Maine Medical Center Research Institute, Scarborough, Maine SENIOR ASSOCIATE EDITORS: Juliet E. Compston, M.D., FRCP, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom Jane B. Lian, Ph.D., University of Massachusetts Medical School, Worcester, Massachusetts This comprehensive yet concise handbook is an indispensable reference for the many clinicians who see patients with disorders of bone formation, metabolic bone diseases, or disorders of stone formation. It is also a crucial tool for researchers, students, and all other professionals working in the bone field. In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders. New in this edition: detailed coverage of osteonecrosis of the jaw, more in-depth coverage of cancer and bone including new approaches to pathogenesis, diagnosis, and treatment; new approaches to anabolic therapy of osteoporosis; the latest research on Vitamin D; expanded coverage of international topics; more on the genetics of bone mass; and newer imaging techniques for the skeleton. In addition, this edition features a free, online-only appendix of medicines used to treat bone disorders and their availability around the world.

Author : Christian Stokes
Publisher : Unknown
Page : 0 pages
File Size : 44,8 Mb
Release : 2023-09-19
Category : Medical
ISBN : 164646592X

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Cellular Metabolism in Health and Disease by Christian Stokes Pdf

Cellular metabolism refers to the set of chemical reactions that take place within the cells of living organisms for maintaining life. Complex sequences of well controlled biochemical reactions are a part of cellular metabolism. These processes enable organisms to develop and reproduce, preserve their structural integrity and adapt to changes in their environment. Cell metabolism reflects the state of the cell's health. The mitochondrion is the primary source of energy for the cell, where bioenergetic processes take place by absorbing fuel sources like fatty acids and glucose. Afterwards, it gets converted into energy through a series of enzymatic reactions. Cellular bioenergetics deregulation results in various pathologies, like neurodegenerative diseases, cancer and diabetes. Cancer is characterized by altered cellular metabolism which aids in the development, growth and maintenance of tumors, as well as malignant transformation. This book contains some path-breaking studies on the role of cellular metabolism in health and disease. Those in search of information to further their knowledge will be greatly assisted by it.

Author : R. Angus Harkness,F. Cockburn
Publisher : Springer
Page : 203 pages
File Size : 44,6 Mb
Release : 1977-11-30
Category : Medical
ISBN : 0852001673

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The Cultured Cell and Inherited Metabolic Disease by R. Angus Harkness,F. Cockburn Pdf

The use of cultured cells in the clinical diagnosis of hereditary metabolic dis ease is a rapidly developing subject to which many different disciplines have brought their expertise and knowledge. A number of scientists who have in dividually contributed to the growth of the subject gave invited papers at the Fourteenth Symposium of the Society for the Study of Inborn Errors of Metabolism in the University of Edinburgh on 13-16th July, 1976. These papers form the basis of this monograph which brings together contributions from the basic sciences and from physicians concerned primarily with human disease. The cross-fertilization produced by this interdisciplinary communica tion was invaluable to those trying to understand and overcome diagnostic problems posed by hereditary metabolic disease. Cell culture methods and cell preservation techniques were described by D. G. Harnden and D. E. Pegg; Dr T. Elsdale outlined some of the factors which control in vitro cell growth and division. Cell culture methods and cryopreser vation techniques have allowed the wide distribution of biochemically abnor mal cells and their study over long periods of time. It is also evident that when a defect which produces severe metabolic disorder in man can be studied in the laboratory using isolated cell cultures a wide variety of investigative procedures can be focused on to the cellular defect without distress or discomfort to the patient or relatives.

Author : Tilman Grune
Publisher : IOS Press
Page : 204 pages
File Size : 41,8 Mb
Release : 2005
Category : Active oxygen
ISBN : 9781586035181

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Free Radicals and Diseases by Tilman Grune Pdf

Author : K. Tada,N.R.M. Buist,John Fernandes,Jean-Marie Saudubray,Georges van den Berghe
Publisher : Springer Science & Business Media
Page : 421 pages
File Size : 55,9 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9783662031476

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Inborn Metabolic Diseases by K. Tada,N.R.M. Buist,John Fernandes,Jean-Marie Saudubray,Georges van den Berghe Pdf

Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.

Author : Ernest Beutler
Publisher : Springer
Page : 288 pages
File Size : 48,8 Mb
Release : 1978-08
Category : Gardening
ISBN : UOM:39015002415779

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Hemolytic Anemia in Disorders of Red Cell Metabolism by Ernest Beutler Pdf

I am prepared to predict that this monograph by Dr. Ernest Beutler will long serve as a model for monographs dealing with topics in medical science. I make this bold statement because we encounter in this work a degree of accuracy and authoritativeness well beyond that found in much of the medical literature. Too often, a monograph is simply a review of past reviews. The preparation of an exhaustive and completely accurate study such as the present one is a very laborious task; consequently, many authors make extensive use of the reviews of earlier writers assum ing that the latter have checked and evaluated each previously published report. Unfortunately, however, this assumption of validity has not al ways been correct. Dr. Beutler, who is a world authority on the subject about which he writes, was determined to make this book as correct and complete as possible, and, to this end, has checked all the original sources. Nowhere else will such an exhaustive bibliography be found. Moreover, he has also undertaken to reevaluate in the light of current knowledge material pub lished in earlier days. This he is eminently able to do, and in some in stances his investigations have resulted in new interpretations. The result is a volume that will be recognized as truly the last word on this important subject.

Author : Christian Ehnholm
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 49,6 Mb
Release : 2009-07-07
Category : Medical
ISBN : 9783642003004

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Cellular Lipid Metabolism by Christian Ehnholm Pdf

For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population
Publisher : National Academies Press
Page : 602 pages
File Size : 40,5 Mb
Release : 2014-09-16
Category : Social Science
ISBN : 9780309306645

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Sociality, Hierarchy, Health by National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population Pdf

Sociality, Hierarchy, Health: Comparative Biodemography is a collection of papers that examine cross-species comparisons of social environments with a focus on social behaviors along with social hierarchies and connections, to examine their effects on health, longevity, and life histories. This report covers a broad spectrum of nonhuman animals, exploring a variety of measures of position in social hierarchies and social networks, drawing links among these factors to health outcomes and trajectories, and comparing them to those in humans. Sociality, Hierarchy, Health revisits both the theoretical underpinnings of biodemography and the empirical findings that have emerged over the past two decades.

Author : Anne Le
Publisher : Springer
Page : 186 pages
File Size : 42,7 Mb
Release : 2018-06-26
Category : Medical
ISBN : 9783319777368

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The Heterogeneity of Cancer Metabolism by Anne Le Pdf

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Author : E. Gilbert-Barness,L.A. Barness,P.M. Farrell
Publisher : IOS Press
Page : 960 pages
File Size : 46,9 Mb
Release : 2017-01-06
Category : MEDICAL
ISBN : 9781614997184

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Metabolic Diseases by E. Gilbert-Barness,L.A. Barness,P.M. Farrell Pdf

The 2nd Edition of Metabolic Diseases provides readers with a completely updated description of the Foundations of Clinical Management, Genetics, and Pathology. A distinguished group of 31 expert authors has contributed 25 chapters as a tribute to Enid Gilbert-Barness and the late Lewis Barness--- both pioneers in this topic. Enid’s unique perspectives on the pathology of genetic disorders and Lew’s unsurpassed knowledge of metabolism integrated with nutrition have inspired the contributors to write interdisciplinary descriptions of generally rare, and always challenging, hereditary metabolic disorders. Discussions of these interesting genetic disorders are organized in the perspective of molecular abnormalities leading to morphologic disturbances with distinct pathology and clinical manifestations. The book emphasizes recent advances such as development of improved diagnostic methods and discovery of new, more effective therapies for many of the diseases. It includes optimal strategies for diagnosis and information on access to specialized laboratories for specific testing. The target audience is a wide variety of clinicians, including pediatricians, neonatologists, obstetricians, maternal-fetal specialists, internists, pathologists, geneticists, and laboratorians engaged in prenatal and/or neonatal screening. In addition, all scientists and health science professionals interested in metabolic diseases will find the comprehensive, integrated chapters informative on the latest discoveries. It is our hope that the 2nd Edition will open new avenues and vistas for our readers and that they will share with us the interest, excitement and passion of the research into all these challenging disorders.

Author : Sybille Mazurek,Maria Shoshan
Publisher : Springer
Page : 374 pages
File Size : 54,6 Mb
Release : 2015-01-19
Category : Medical
ISBN : 9783709118245

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Tumor Cell Metabolism by Sybille Mazurek,Maria Shoshan Pdf

The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.

Author : Thomas Seyfried
Publisher : John Wiley & Sons
Page : 482 pages
File Size : 44,6 Mb
Release : 2012-05-18
Category : Science
ISBN : 9781118310304

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Cancer as a Metabolic Disease by Thomas Seyfried Pdf

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Author : Charles R. Scriver
Publisher : New York ; Montreal : McGraw-Hill
Page : 6338 pages
File Size : 51,7 Mb
Release : 2001
Category : Genetic disorders
ISBN : 007136319X

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The Metabolic & Molecular Bases of Inherited Disease by Charles R. Scriver Pdf

Presents clinical, biochemical, and genetic information concerning those metabolic anomalies grouped under inborn errors of metabolism.