Cellular Transforming Genes

Author : Anonim
Publisher : Unknown
Page : 4 pages
File Size : 53,5 Mb
Release : 1986
Category : Cells
ISBN : MINN:30000010710451

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Cellular Transforming Genes by Anonim Pdf

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 50,7 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : J. Celis,A. Graessmann
Publisher : Springer Science & Business Media
Page : 321 pages
File Size : 43,8 Mb
Release : 2013-03-09
Category : Mathematics
ISBN : 9781468450095

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Cell Transformation by J. Celis,A. Graessmann Pdf

Author : J. E. Celis
Publisher : Springer Science & Business Media
Page : 439 pages
File Size : 45,9 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781468445411

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Gene Expression in Normal and Transformed Cells by J. E. Celis Pdf

This volume is based on the proceedings of a NATO-Gulbenkian Foundation sponsored Summer School held in May-June 1982 in Sintra Estoril, Portugal. Given the accelerated growth of knowledge in the field of eukaryotic gene expression, it seemed timely to hold a NATO Advanced Study Institute to discuss current developments in this area of biology and to evaluate the potential of emerging technologies such as gene transfer, recombinant DNA cloning and quantitative high resolution two-dimensional gel electrophoresis. The initial articles in t~is volume describe various differentiation models and address questions such as the relationships between differentiation and cell proliferation, biochemical changes accompanying differen tiation, expression of differentiated gene products and their regulation as well as gene organization of cytoskeletal proteins. The second section describes properties of neoplastic cells, surveys current assays for transformation and offers some new insights into the mechanisms involved in carcinogenesis. The third part is dedicated to viral oncogenesis and to the role of onco genes in cell transformation. Particular emphasis is given to the role of tyrosine kinases in cell transformation. The concluding section deals with various aspects of gene expression in normal and transformed cells with special emphasis given to studies using two dimensional gel electrophoresis, cell hybridization, gene transfer and immunological techniques.

Author : R. Neth,R. C. Gallo,M. F. Greaves,M. A. S. Moore,K. Winkler
Publisher : Springer Science & Business Media
Page : 539 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642687617

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Modern Trends in Human Leukemia V by R. Neth,R. C. Gallo,M. F. Greaves,M. A. S. Moore,K. Winkler Pdf

Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie, Wilsede, June 21-23, 1982

Author : Kathy B. Burck,Edison T. Liu,James W. Larrick
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461237181

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Oncogenes by Kathy B. Burck,Edison T. Liu,James W. Larrick Pdf

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.

Author : Roland F. Beers,R. Carmichael Tilghman
Publisher : Unknown
Page : 360 pages
File Size : 48,8 Mb
Release : 1973
Category : Health & Fitness
ISBN : UCAL:B4300251

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Cellular Modification and Genetic Transformation by Exogenous Nucleic Acids by Roland F. Beers,R. Carmichael Tilghman Pdf

Author : Alecsandru Ioan Baba,Cornel Cătoi
Publisher : Unknown
Page : 787 pages
File Size : 44,8 Mb
Release : 2007
Category : Electronic books
ISBN : 9732714573

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Comparative Oncology by Alecsandru Ioan Baba,Cornel Cătoi Pdf

Author : Maclyn McCarty
Publisher : W. W. Norton & Company
Page : 258 pages
File Size : 49,7 Mb
Release : 1986
Category : Philosophy
ISBN : 0393304507

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The Transforming Principle by Maclyn McCarty Pdf

Forty years ago, three medical researchers--Oswald Avery, Colin MacLeod, and Maclyn McCarty--made the discovery that DNA is the genetic material. With this finding was born the modern era of molecular biology and genetics.

Author : J. Celis,A. Graessmann
Publisher : Springer
Page : 332 pages
File Size : 55,6 Mb
Release : 2012-03-22
Category : Mathematics
ISBN : 1468450115

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Cell Transformation by J. Celis,A. Graessmann Pdf

This volume is based on the proceedings of a NATOjFEBSjGulbenkian Foundation sponsored Summer School held in September 1984 in Sintra Estoril, Portugal. Given the accelerated growth of knowledge in the field of cell transformation, it seemed timely to hold a summer school to discuss current developments in this area of biology as well as to evaluate emerging technology. The first article in this volume gives an evaluation of the various cellular systems to study neoplasia. Their properties as well as advantages and disadvantages are dis cussed. The second section deals with the role of oncogenes in cell transformation. Particular emphasis is given to the question of whether activated proto-one genes are cancer genes and to the func tions of oncogene products. The third part is dedicated to viruses and includes articles on papova viruses, Epstein-Barr virus, adeno virus, parvo viruses and HTLV. The fourth part deals with gene ex pression in normal and transformed cells while the concluding sec tion considers various aspects of gene regulation in eukaryotic cell s. vi PREFACE We wish to express our appreciation to Dr. Maria C. Lechner who provided valuable advice and help concerning the organization of this meeting. We are also indebted to Ms. Lisbeth Heilesen and Ms. Anne Mette Lygaard for typing the manuscripts and for their out standing administration of the meeting. J. E. Cel is February 1985 A. Graessmann CONTENTS NEOPLASTIC TRANSFORMATION SYSTEMS 1. Neoplastic Transformation Systems - Their Use In Stu- ing Carcinogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Author : Johng S. Rhim,Anatoly Dritschilo,Richard Kremer
Publisher : Springer Nature
Page : 246 pages
File Size : 47,9 Mb
Release : 2019-10-01
Category : Science
ISBN : 9783030222543

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Human Cell Transformation by Johng S. Rhim,Anatoly Dritschilo,Richard Kremer Pdf

This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.

Author : William J. Gradishar,William C. Wood
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 40,6 Mb
Release : 2000-08-31
Category : Medical
ISBN : 0792378903

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Advances in Breast Cancer Management, 2nd edition by William J. Gradishar,William C. Wood Pdf

The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.

Author : Sam Thiagalingam
Publisher : Cambridge University Press
Page : 597 pages
File Size : 50,6 Mb
Release : 2015-04-09
Category : Mathematics
ISBN : 9780521493390

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Systems Biology of Cancer by Sam Thiagalingam Pdf

An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Author : Ivan Cameron
Publisher : Elsevier
Page : 452 pages
File Size : 45,8 Mb
Release : 1981-01-01
Category : Science
ISBN : 9780323162968

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The Transformed Cell by Ivan Cameron Pdf

The Transformed Cell deals with many of the differences that may exist between transformed cells and their normal counterparts. Topics covered range from malignancy and the cell surface to cell cycle regulation in normal and transformed cells; phenotypic expression of malignant transformation and its relationship to energy metabolism; and virus-induced transformation. The involvement of cyclic nucleotides in transformation is also discussed, together with intracellular pH and growth control in eukaryotic cells. This book is comprised of 12 chapters and begins with a brief description of terminology and basic concepts relating to cancer cells, as well as some comments on tumorigenicity and cell transformation. The next two chapters explore the evidence for and against the possible correlation of in vivo tumorigenicity to in vitro changes in the cytoskeletal system; anchorage-dependent growth; plasminogen activator production; agglutinability by lectins; and cell surface and plasma membrane properties. The regulation of cell proliferation and the relationships between ion movement and energy metabolism in normal and transformed cells are then examined, along with the transformation of normal cells by infection with new genetic material from tumor viruses. The remaining chapters focus on selected cellular properties that have been purported to differ between the normal and transformed cell, with particular reference to cyclic nucleotides; polyamine metabolism; cell viscosity; mobility of cellular water; intracellular pH; and element concentration. This monograph will be of interest to biologists and medical practitioners devoted to understanding cancer cell biology and cancer therapy.