Challenges In Nonhuman Primate Research In The 21st Century

Author : Gerhard F. Weinbauer,Friedhelm Vogel
Publisher : Waxmann Verlag
Page : 180 pages
File Size : 50,9 Mb
Release : 2013
Category : Medical
ISBN : 9783830978398

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Challenges in Nonhuman Primate Research in the 21st Century by Gerhard F. Weinbauer,Friedhelm Vogel Pdf

In continuation of the Covance Primate Symposium Series, the 19th Covance Primate Symposium took place in Münster on 23rd & 24th of May 2012. Altogether, 70 participants representing 43 organisations, gathered for this symposium. The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate Research in the 21st Century?. The broad participation and the lively discussions during the symposium underlined the timeliness and importance of this topic. Expert speakers covered four major topics, i.e. biosimilars development: regulatory implications, key considerations and next steps, optimizing nonhuman primate use in nonclinical safety assessment, trends in nonhuman primate developmental & reproductive toxicology (DART) and juvenile toxicity evaluation, and relevance and importance of nonhuman primate models in regulatory toxicology. The development of biosimilar has taken up speed considerably and meanwhile needs to be considered a significant factor of potential drug development, yet there are still some uncertainties und guidelines are under development. With the increased focus on biopharmaceuticals and the associated increase for using nonhuman primates being the relevant animal model, it became necessary to optimize the use of this animal model, e.g. refine study designs and animals numbers but still execute meaningful preclinical studies. It appears that significant progress has been achieved in that context. In the area of nonhuman primate DART and juvenile toxicity evaluation, recent guideline changes had a major impact on species selection, and the experimental design plus the timing of these studies within the preclinical programmes. Finally, given the increasing regulations and justficiations of using nonhuman primates as experimental models. It is paramount to understand the essential and indispensable role that nonhuman primates can play in drug safety evaluation and medical drug development.

Author : Michel T. Waller
Publisher : Springer
Page : 422 pages
File Size : 45,5 Mb
Release : 2016-07-28
Category : Science
ISBN : 9783319304694

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Ethnoprimatology by Michel T. Waller Pdf

The list of challenges facing nonhuman primates in the 21st century is a long one. The expansion of palm oil plantations to feed a growing consumer class is eating away at ape and monkey habitats in Southeast Asia and Central Africa. Lemurs are hunted for food in the poorest parts of Madagascar while monkeys are used as medicine in Brazil. Traditional cultural beliefs are maintaining demand for animal body parts in West African markets while viral YouTube videos of “cute” and “cuddly” lorises have increased their market value as pets and endangered their populations. These and other issues are addressed in this book by leading researchers in the field of ethnoprimatology, the study of human/nonhuman primate interactions that combines traditional primatological methodologies with cultural anthropology in an effort to better understand the nuances of our economic, ritualistic, and ecologic relationships.

Author : National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Well-Being of Nonhuman Primates
Publisher : National Academies Press
Page : 184 pages
File Size : 48,7 Mb
Release : 1998-11-03
Category : Science
ISBN : 9780309176507

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The Psychological Well-Being of Nonhuman Primates by National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Well-Being of Nonhuman Primates Pdf

A 1985 amendment to the Animal Welfare Act requires those who keep nonhuman primates to develop and follow appropriate plans for promoting the animals' psychological well-being. The amendment, however, provides few specifics. The Psychological Well-Being of Nonhuman Primates recommends practical approaches to meeting those requirements. It focuses on what is known about the psychological needs of primates and makes suggestions for assessing and promoting their well-being. This volume examines the elements of an effective care program--social companionship, opportunities for species-typical activity, housing and sanitation, and daily care routines--and provides a helpful checklist for designing a plan for promoting psychological well-being. The book provides a wealth of specific and useful information about the psychological attributes and needs of the most widely used and exhibited nonhuman primates. Readable and well-organized, it will be welcomed by animal care and use committees, facilities administrators, enforcement inspectors, animal advocates, researchers, veterinarians, and caretakers.

Author : Kerry M. Dore,Erin P. Riley,Agustin Fuentes
Publisher : Unknown
Page : 128 pages
File Size : 48,5 Mb
Release : 2017
Category : Ethnology
ISBN : 1107525586

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Ethnoprimatology by Kerry M. Dore,Erin P. Riley,Agustin Fuentes Pdf

"Ethnoprimatology, the combining of primatological and anthropological practice and the viewing of humans and other primates as living in integrated and shared ecological and social spaces, has become an increasingly popular approach to primate studies in the twenty-first century. Offering an insight into the investigation and documentation of human-nonhuman primate relations in the Anthropocene, this book guides the reader though the preparation, design, implementation, and analysis of an ethnoprimatological research project, offering practical examples of the vast array of methods and techniques at chapter level. With contributions from the world's leading experts in the field, Ethnoprimatology critically analyses current primate conservation efforts, outlines their major research questions, theoretical bases and methods, and tackles the challenges and complexities involved in mixed-methods research. Documenting the spectrum of current research in the field, it is an ideal volume for students and researchers in ethnoprimatology, primatology, anthropology, and conservation biology"--

Author : Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
Publisher : Springer
Page : 0 pages
File Size : 49,8 Mb
Release : 2011-12-15
Category : Medical
ISBN : 3642849083

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Nonhuman Primates I by Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt Pdf

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo nographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stu dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre pared under the sponsorship of the International Life Sciences Institute (ILSI).

Author : Kerry M. Dore,Erin P. Riley,Agustín Fuentes
Publisher : Cambridge University Press
Page : 327 pages
File Size : 46,9 Mb
Release : 2017-02-23
Category : Nature
ISBN : 9781107109964

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Ethnoprimatology by Kerry M. Dore,Erin P. Riley,Agustín Fuentes Pdf

A how-to guide for ethnoprimatological research in the Anthropocene, offering an inside look at the latest research in the field.

Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 113 pages
File Size : 42,7 Mb
Release : 1988-02-01
Category : Science
ISBN : 9780309038393

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Use of Laboratory Animals in Biomedical and Behavioral Research by National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research Pdf

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
Publisher : Academic Press
Page : 716 pages
File Size : 49,5 Mb
Release : 2015-03-13
Category : Medical
ISBN : 9780124171466

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The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment by Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer Pdf

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

Author : Gene P. Sackett,Gerald Ruppenthal,Kate Elias
Publisher : Springer Science & Business Media
Page : 602 pages
File Size : 41,6 Mb
Release : 2010-05-10
Category : Medical
ISBN : 9780387256405

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Nursery Rearing of Nonhuman Primates in the 21st Century by Gene P. Sackett,Gerald Ruppenthal,Kate Elias Pdf

Nursery Rearing of Nonhuman Primates in the 21st Century describes how and why nursery rearing of primates can produce adaptable juveniles and adults for research, conservation, and display-educational purposes. The volume details the history of nursery rearing since the mid-19th century, the outcomes of varied nursery rearing methods, the contemporary goals of nursery rearing as well as reference data derived from species commonly reared in nursery or hand-feeding situations. Examples of the changing goals of nursery rearing covered in this volume are the need for biological containment in disease research, the production of specific pathogen-free colonies by removal of neonates from the mother, the production of phenotypes for genetic and molecular biology studies, and the breeding of endangered species for conservation or research purposes.

Author : Anonim
Publisher : Unknown
Page : 16 pages
File Size : 42,9 Mb
Release : 2005
Category : Animal behavior
ISBN : UCBK:C094385531

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Enrichment for Nonhuman Primates by Anonim Pdf

Author : Kathrin Herrmann,Kimberley Jayne
Publisher : Unknown
Page : 0 pages
File Size : 47,8 Mb
Release : 2019
Category : Animal experimentation
ISBN : 9004356185

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Animal Experimentation by Kathrin Herrmann,Kimberley Jayne Pdf

Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

Author : Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publisher : Academic Press
Page : 868 pages
File Size : 45,8 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9780123978387

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Nonhuman Primates in Biomedical Research by Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris Pdf

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

Author : Asif A. Ghazanfar
Publisher : Oxford University Press, USA
Page : 706 pages
File Size : 50,6 Mb
Release : 2012-08-16
Category : Medical
ISBN : 9780199929245

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Primate Neuroethology by Asif A. Ghazanfar Pdf

This edited volume is the first of its kind to bridge the epistemological gap between primate ethologists and primate neurobiologists. Leading experts in several fields review work ranging from primate foraging behavior to the neurophysiology of motor control, from vocal communication to the functions of the auditory cortex.

Author : Lynn Hankinson Nelson
Publisher : Cambridge University Press
Page : 279 pages
File Size : 52,6 Mb
Release : 2017-09-07
Category : Science
ISBN : 9781107090187

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Biology and Feminism by Lynn Hankinson Nelson Pdf

A balanced and accessible introduction to the engagements that feminist scientists and science scholars undertake with a variety of biological sciences.

Author : Jin-Hua Li,Lixing Sun,Peter M. Kappeler
Publisher : Springer Nature
Page : 303 pages
File Size : 47,6 Mb
Release : 2019-11-18
Category : Science
ISBN : 9783030279202

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The Behavioral Ecology of the Tibetan Macaque by Jin-Hua Li,Lixing Sun,Peter M. Kappeler Pdf

This open access book summarizes the multi-disciplinary results of one of China’s main primatological research projects on the endemic Tibetan macaque (Macaca thibetana), which had continued for over 30 years, but which had never been reported on systematically. Dedicated to this exceptional Old World monkey, this book makes the work of Chinese primatologists on the social behavior, cooperation, culture, cognition, group dynamics, and emerging technologies in primate research accessible to the international scientific community. One of the most impressive Asian monkeys, and the largest member of its genus, the Tibetan macaque deserves to be better known. This volume goes a long way towards bringing this species into the spotlight with many excellent behavioral analyses from the field. - Frans de Waal, Professor of Psychology, Emory University, USA. Macaques matter. To understand primate patterns and trends, and to gain important insight into humanity, we need to augment and expand our engagement with the most successful and widespread primate genus aside from Homo. This volume focuses on the Tibetan macaque, a fascinating species with much to tell us about social behavior, physiology, complexity and the macaque knack for interfacing with humans. This book is doubly important for primatology in that beyond containing core information on this macaque species, it also reflects an effective integrated collaboration between Chinese scholars and a range of international colleagues—exactly the type of collaborative engagement primatology needs. This volume is a critical contribution to a global primatology. - Agustín Fuentes, Professor of Anthropology, University of Notre Dame, USA. I have many fond memories of my association with Mt. Huangshan research beginning in 1983, when together with Professor Qishan Wang we established this site. It is such a beautiful place and I miss it. It is gratifying to see how far research has progressed since we began work there, becoming more internationalized and very much a collaborative endeavor under the long-term direction of Professor Jin-Hua Li and colleagues. This book highlights the increased interest in this species, representing a variety of disciplines ranging from macro aspects of behavior, cognition and sociality, to micro aspects of microbes, parasites and disease, authored by a group of renowned Chinese and international primatologists. I applaud their efforts and expect more interesting work to come from this site in the years ahead. - Kazuo Wada, Professor Emeritus, Kyoto University, Japan.