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Characterization of Biological Membranes by Mu-Ping Nieh,Frederick A. Heberle,John Katsaras Pdf
The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes. The current book is an excellent introduction to the area, which explains how modern analytical methods can be applied to study biological membranes and membrane proteins and the bioprocesses they are involved to.
Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis by Robert Brasseur Pdf
The goal of these two volumes is to help fill the gap between theory and experiment in membrane science. This is the only work available today which covers the domain of computer-aided conformational analyses of membranes. Written in a detailed, yet comprehensive manner, this book uses the semi-empirical approach as a way to give a molecular description of the membrane structure in organized systems. This interesting work establishes the validity and quality of the prediction by making a permanent comparison with the experimental data. This reference aims to use this comparison to open a new avenue in the molecular description of the biological membrane. Those involved with biochemistry, biophysics, pharmacology, and biology will find these volumes interesting and informative.
Membrane Characterization by Nidal Hilal,Ahmad Fauzi Ismail,Takeshi Matsuura,Darren Oatley-Radcliffe Pdf
Membrane Characterization provides a valuable source of information on how membranes are characterized, an extremely limited field that is confined to only brief descriptions in various technical papers available online. For the first time, readers will be able to understand the importance of membrane characterization, the techniques required, and the fundamental theory behind them. This book focuses on characterization techniques that are normally used for membranes prepared from polymeric, ceramic, and composite materials. Features specific details on many membrane characterization techniques for various membrane materials of industrial and academic interest Contains examples of international best practice techniques for the evaluation of several membrane parameters, including pore size, charge, and fouling Discusses various membrane models more suitable to a specific application Provides examples of ab initio calculations for the design, optimization, and scale-up of processes based on characterization data
Membrane Proteins by Angelo Azzi,Lanfranco Masotti,Arnaldo Vecli Pdf
This volume is the third of a series on Membrane Proteins and, like the pre ceding manuals, is the result of an International Advanced Course entitled Isolation and Characterization of Membrane Proteins: Biochemical and Bio physical Aspects sponsored by the Federation of European Biochemical So cieties (FEBS) and the Italian Research Council (CNR). The success of the course and the continuous development in the field of membrane biology has prompted me to publish also in this case the protocols of the experiments which were carried out by the students. The students have been able not only to perform the experiments pub lished in this manual without help from the instructors, but also to suggest improvements, which have been incorporated in the published version. Care has been taken in making the planning and the execution of the ex periments as simple as possible, by listing in detail all the necessary pieces of equipment, test tubes, pipettes, chemicals, etc. At the same time the intro duction and the "philosophy" have been limited to the essential, as also the references, only those having been listed which may help in a better under standing of the principles and of the biological background of a given experi ment.
Transport Across Natural and Modified Biological Membranes and its Implications in Physiology and Therapy by Julita Kulbacka,Saulius Satkauskas Pdf
This book elucidates the mechanisms involved in biological membrane functions. It describes the new modalities and characterization for basic in vitro as well as computer models of biological membranes. Biological membranes are analyzed in terms of advances in molecular dynamics. The individual chapters provide an in depth analysis of images from various biological models. The potential of membrane models in the context of treatment trials is discussed. The authors present new insights and current concepts for treatment procedures (nanocarriers, electroporation, channel blockers).
Biological Membranes by Kenneth M. Merz,Benoit Roux Pdf
The interface between a living cell and the surrounding world plays a critical role in numerous complex biological processes. Sperm/egg fusion, virus/cell fusion, exocytosis, endocytosis, and ion permeation are a few examples of processes involving membranes. In recent years, powerful tools such as X-ray crystal lography, electron microscopy, nuclear magnetic resonance, and infra-red and Raman spectroscopy have been developed to characterize the structure and dy namics of biomembranes. Despite this progress, many of the factors responsible for the function of biomembranes are still not well understood. The membrane is a very complicated supramolecular liquid-crystalline structure that is largely composed of lipids, forming a bilayer, to which proteins and other biomolecules are anchored. Often, the lipid bilayer environment is pictured as a hydropho bic structureless slab providing a thermodynamic driving force to partition the amino acids of a membrane protein according to their solubility. However, much of the molecular complexity of the phospholipid bilayer environment is ignored in such a simplified view. It is likely that the atomic details of the polar head group region and the transition from the bulk water to the hydrophobic core of the membrane are important. An understanding of the factors responsible for the function of biomembranes thus requires a better characterization at the molec ular level of how proteins interact with lipid molecules, of how lipids affect protein structure and of how lipid molecules might regulate protein function.
Fluorescent Methods to Study Biological Membranes by Yves Mely,Guy Duportail Pdf
Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.
The Physical Chemistry of MEMBRANES by B. Silver Pdf
Ls book is an account of what physical chemistry h . . to say about the structural, electrical and transport properties of biological membranes and their simplest model-the lipid bilayer. The accent throughout is on basic ideas. In contrast to the essentially descriptive ap proach characteristic of texts on membrane biochemistry, our underlying themes are the role of force and entropy in maintaining membrane organization, in determining the electric fields and ionic environment of membranes, and in regulating the passage of molecules and ions across membranes. Although experimental findings will always be the touch stone against which theory will be tried, no attempt is made to present an exhaustive survey of experimental data. On the other hand, there is discussion of the nature and limitations of the results obtainable by the major laboratory techniques. The treatment is at the level of an advanced undergraduate course or an introductory survey suitable for post graduate students carrying out research in biochemistry, biophysics, or physiology. The mathematical demands on the reader are trivial. The few forbidding equations appearing in Chapter 7 are soon whittled away to simple practical expressions. Although the current-voltage characteristics of nerves are traditionally the province of biophysics rather than physical chemistry, certain aspects relevant to the electrical activity of nerves are nevertheless included in this text, namely, mem brane and diffusion potentials and conductivity fluctuations. Where rival theories exist, conflicting convictions have been presented, but not necessarily accorded equal approbation. The author has a viewpoint.
AMolecular Description of Biological Membrane Components by Computer Aided Conformational Analysis by Robert Brasseur Pdf
First published in 1990, the goal of these two volumes is to help fill the gap between theory and experiment in membrane science. Those involved with biochemistry, biophysics, pharmacology, and biology will find these volumes interesting and informative.
Structure and Properties of Cell Membrane Structure and Properties of Cell Membranes by Benga Pdf
This book provides in-depth presentations in membrane biology by specialists of international repute. The volumes examine world literature on recent advances in understanding the molecular struc-ture and properties of membranes, the role they play in cellular physiology and cell-cell interactions, and the alterations leading to abnormal cells. Illustrations, tables, and useful appendices com-plement the text. Those professionals actively working in the field of cell membrane investigations as well as biologists, biochemists, biophysicists, physicians, and academicians, will find this work beneficial.
Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis by Robert Brasseur Pdf
The goal of these two volumes is to help fill the gap between theory and experiment in membrane science. This is the only work available today which covers the domain of computer-aided conformational analyses of membranes. Written in a detailed, yet comprehensive manner, this book uses the semi-empirical approach as a way to give a molecular description of the membrane structure in organized systems. This interesting work establishes the validity and quality of the prediction by making a permanent comparison with the experimental data. This reference aims to use this comparison to open a new avenue in the molecular description of the biological membrane. Those involved with biochemistry, biophysics, pharmacology, and biology will find these volumes interesting and informative.
Physics of Biological Membranes by Patricia Bassereau,Pierre Sens Pdf
This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.
Synthetic Polymeric Membranes by K. C. Khulbe,C. Y. Feng,Takeshi Matsuura Pdf
Researchers in polymeric membranes as well as R&D professionals will find this work an essential addition to the literature. It concentrates on the method recently developed to study the surfaces of synthetic polymeric membranes using an Atomic Force Microscope (AFM), which is fast becoming a very important tool. Each chapter includes information on basic principles, commercial applications, an overview of current research and guidelines for future research.
