Chirality From Molecular Electronic States

Author : Takashiro Akitsu
Publisher : BoD – Books on Demand
Page : 130 pages
File Size : 43,9 Mb
Release : 2019-02-06
Category : Science
ISBN : 9781789851557

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Chirality from Molecular Electronic States by Takashiro Akitsu Pdf

In chemistry, biology, and physics, "chirality" is an important concept in nature. Especially in chemistry, not only classical stereochemistry but also asymmetric organic synthesis, supramolecular chemistry, construction of bio-related molecules and molecular recognition became indispensable structural chemical keywords. However, in view of synthetic chemistry and its structural chemistry, chemistry dealing with chirality in relation to the more fundamental electronic state is still a minority. This book is particularly aimed at chiroptical spectroscopy, structural or physical features and theoretical computation of chirality.

Author : Takashiro Akitsu
Publisher : Unknown
Page : 128 pages
File Size : 55,6 Mb
Release : 2019
Category : Chemistry, Organic
ISBN : 1789851564

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Chirality from Molecular Electronic States by Takashiro Akitsu Pdf

In chemistry, biology, and physics, ""chirality"" is an important concept in nature. Especially in chemistry, not only classical stereochemistry but also asymmetric organic synthesis, supramolecular chemistry, construction of bio-related molecules and molecular recognition became indispensable structural chemical keywords. However, in view of synthetic chemistry and its structural chemistry, chemistry dealing with chirality in relation to the more fundamental electronic state is still a minority. This book is particularly aimed at chiroptical spectroscopy, structural or physical features and theoretical computation of chirality.

Author : Kumar Challa,Buranaprapuk Apinya
Publisher : World Scientific
Page : 448 pages
File Size : 48,6 Mb
Release : 2018-10-26
Category : Science
ISBN : 9789813237636

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Chiral Photochemical Scissors Targeting Proteins by Kumar Challa,Buranaprapuk Apinya Pdf

The remarkable ability to target one or even a couple of sites on a large protein with a small molecule, under photochemical control, is a considerable challenge and this challenge has been addressed in some depth in this book. Systematic modification of the structure of the photoreagent provided valuable information on the binding site recognition as well as the mechanism of the photocleavage reaction. Some factors that impact the photocleavage reaction include the exact location of the probe binding site on the protein, conformations of the bound probe at the binding site, protein size, functional groups present on the probe that interact with the protein surroundings either in a favorable or unfavorable manner, overall charge on the photoreagent, and photophysical as well as photochemical properties of the probe. The protein photocleavage studies, in all case, were preceded by detailed binding studies by a variety of spectroscopic methods. Methods as simple as absorption and fluorescence spectroscopies or more sophisticated circular dichroism spectroscopy were used. Conclusions that are most consistent with the binding data indicated a single binding site on most proteins, irrespective of the probe or the protein, with only one exception noted so far. Photoactivation of the bound probe resulted in protein cleavage at a single site, in many instances. The specificity for the reaction has been investigated in detail and molecular modeling studies provided a firm ground to rationalize the observed cleavage sites. The reagents provide unique tools for sequencing large proteins by converting them into smaller fragments by non-biochemical transformations. Understanding of the rules for the above methodology are also investigated which provided rational methods for the design of small molecules that could bind at particular sites on large proteins, and this is a major breakthrough for a variety of fields including drug design, protein targeting, mass spectrometry, proteomics and other cutting-edge research areas.

Author : Ron Naaman,David N Beratan,David Waldeck
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 44,8 Mb
Release : 2011-01-25
Category : Science
ISBN : 9783642181030

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Electronic and Magnetic Properties of Chiral Molecules and Supramolecular Architectures by Ron Naaman,David N Beratan,David Waldeck Pdf

Time-dependent density functional response theory for electronic chiroptical properties of chiral molecules; by Jochen Autschbach, Lucia Nitsch–Velasquez, and Mark Rudolph * Chiroptical Properties of Charge-Transfer Compounds; by Yoshihisa Inoue, Tadashi Mori * G-C content independent long-range charge transfer through DNA; by Tetsuro Majima * Induced chirality in porphiryn aggregates: the role of weak and strong interactions; by Roberto Purrello * Vibrational circular dichroism spectroscopy of chiral molecules in solution; by Yunjie Xu * Magneto-electric properties of self-assembled monolayers of chiral molecules; by Zeev Vager and Ron Naaman * Theory of adsorption induced chirality and electron transfer through chiral systems; by Spiros Skourtis and David Beratan * Chiral-selective surface chemistry induced by spin-polarized secondary electrons; by Richard Rosenberg

Author : S. H. Lin
Publisher : World Scientific
Page : 303 pages
File Size : 54,6 Mb
Release : 2008
Category : Science
ISBN : 9789812791740

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Advances in Multi-Photon Processes and Spectroscopy by S. H. Lin Pdf

This book presents the latest developments and issues in both experimental and theoretical studies of multi-photon processes and the spectroscopy of atoms, ions and molecules in physics, chemistry, biology and material science. It contains review papers suitable for both active researchers and non-experts who wish to enter the field.Special attention is paid to the recent progress of non-linear photonOComatter interactions in atoms, molecules and interfaces: XUV/soft X-ray, high-order harmonic generation in attosecond regime, high-order harmonic generation, sum frequency generation, four-wave mixing spectroscopy and molecular orientation with combined electrostatic and intense, non-resonant laser fields.

Author : Stephen F. Mason
Publisher : Cambridge University Press
Page : 300 pages
File Size : 51,9 Mb
Release : 1982-10-14
Category : Medical
ISBN : 0521247020

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Molecular Optical Activity and the Chiral Discriminations by Stephen F. Mason Pdf

Good,No Highlights,No Markup,all pages are intact, Slight Shelfwear,may have the corners slightly dented, may have slight color changes/slightly damaged spine.

Author : Gyula Palyi,Claudia Zucchi,Luciano Caglioti
Publisher : Elsevier
Page : 445 pages
File Size : 46,7 Mb
Release : 2004-12-13
Category : Science
ISBN : 9780080474038

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Progress in Biological Chirality by Gyula Palyi,Claudia Zucchi,Luciano Caglioti Pdf

Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach to this exciting field, covering a wide range of topics, such as, theory, palaeontology and food technology, to name but a few. This book presents findings via a broad spectrum of scientific approaches making it an excellent overview of Biological Chirality, suitable for postgraduate students, practitioners and researchers in the field of chemistry, biochemistry, biology, palaeontology, and food science with an interest in Chirality. This book contains 32 chapters written by Authors, who are leading authorities in the field Presents the most recent research taking place in this highly challenging field Contains both reference material for the specialist and provides an overview for those who are interested in the fundamental problems of biology and chemistry

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 41,5 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9789814469166

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Electronic and Nuclear Dynamics in Molecular Systems by Anonim Pdf

Author : S.F. Mason
Publisher : Springer Science & Business Media
Page : 375 pages
File Size : 51,8 Mb
Release : 2013-03-14
Category : Science
ISBN : 9789401576444

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Optical Activity and Chiral Discrimination by S.F. Mason Pdf

For Louis Pasteur, the two distinctive properties of dissymmetric systems, optical activity and chiral discrimination, provided prime evidence for a Divine origin to the universe. Handedness appeared to be built into the macrocosm of the galaxies, each with a non-superposable mirror image by virtue of its rotation, as well as the microcosm of each molecule of most natural products. The best that the chemist in the laboratory could accomplish appeared to be the synthesis of the detordu internally-compensated meso-form and, as Pasteur ultimately came to admit, the externally-compensated racemic form. In the latter case the chemist generated not merely one but two chiral structures, although parity, and secondary symmetry generally, seemed to be conserved in the enantiomer antipode pair. The cosmic element in the Pasteur tradition received an augmentation in secular form from demonstrations of the non conservation of parity in the weak interactions, and from the discovery of net circularity in the extra-terrestrial photons, such as those from the less-distant planets, particularly the photons from the Jupiter red-spot. The development of the photoacoustic circular analysers a decade ago was received in fact with as much enthusiasm by the astronomers as by the chemists. It would be just to add, however, that the majority of these circular analysers are now to be found, not in the observatories, but in the physical and chemistry laboratories devoted to the molecular aspects of the Pasteur tradition.

Author : Paul G. Mezey
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 44,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401136983

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New Developments in Molecular Chirality by Paul G. Mezey Pdf

Molecular chirality is one of the fundamental aspects of chemistry. Chirality properties of molecules have implications in a wide variety of subjects, ranging from the basic quantum mechanical properties of simple of a few atoms to molecular optical activity, asymmetric synthesis, systems and the folding pattern of proteins. Chirality, in both the geometrical and the topological sense, has also been the subject of investigations in various branches of mathematics. In particular, new developments in a branch of topology, called knot theory, as well as in various branches of discrete mathematics, have led to a novel perspective on the topological aspects of molecular chirality. Some of the mathematical advances have already found applications to the interpretation of new concepts in theoretical chemistry and mathematical chemistry, as well as to novel synthetic approaches leading to new molecules of exceptional structural properties. Some of the new developments in molecular chirality have been truly fundamental to the theoretical understanding and to the actual practice of many aspects of chemistry. The progress in this field has been very rapid, even accelerating in recent years, and a review appears more than justified. This book offers a selection of subjects covering some of the latest developments. Our primary aim is to clarify some of the basic concepts that are the most prone to misinterpretation and to provide brief introductions to some of those subjects that are expected to have further, important contributions to our understanding of molecular properties and chemical reactivity.

Author : P.L. Polavarapu
Publisher : Elsevier
Page : 824 pages
File Size : 55,9 Mb
Release : 2018-05-30
Category : Science
ISBN : 9780444640284

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Chiral Analysis by P.L. Polavarapu Pdf

Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu

Author : Chuanlai Xu
Publisher : John Wiley & Sons
Page : 308 pages
File Size : 45,5 Mb
Release : 2022-05-04
Category : Technology & Engineering
ISBN : 9783527833597

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Chiral Nanoprobes for Biological Applications by Chuanlai Xu Pdf

A comprehensive overview exploring the biological applications of chiral nanomaterials Chirality has been the centerpiece of many multidisciplinary fields within the broader umbrella of the sciences. Recent advancements in nanoscience have spurred a growing interest in the dynamic field of chiral nanomaterials. In particular, the recent breakthroughs in chiral nanocrystals have presented an intriguing avenue whose potential application may address some key issues at the heart of nanosciences. While little attention has been focused on the biological implications of such advances, this arena is attracting theoretical and applicative interests. Seeking to provide a thorough introduction to the field as well as fill this gap in scholarship, Chiral Nanoprobes for Biological Applications first provides a comprehensive review of the state-of-the-art development of strong chiroptical nanomaterials, describing how a synthesis and self-assembly approach can enable one to design and create a number of functional chiral nanomaterials. From there, the authors discuss the biological applications of chiral nanomaterials, such as extracellular bioanalysis, intracellular bioanalysis, and chiral recognition, as well as photothermal and photodynamics therapy. In doing so, the book seeks emphasize the potential in multidisciplinary approaches to this up-and-coming field. Chiral Nanoprobes for Biological Applications readers will also find: A particular emphasis on milestones achieved for key chiral nanoprobes research from the last five years A discussion of future research directions A helpful guide for new researchers and established professionals alike Chiral Nanoprobes for Biological Applications is a useful reference for materials scientists, biochemists, protein chemists, stereo chemists, polymer chemists, and physical chemists. It is also a useful tool for libraries.

Author : Imran Ali,Hassan Y. Aboul-Enein
Publisher : John Wiley & Sons
Page : 368 pages
File Size : 44,7 Mb
Release : 2005-07-15
Category : Science
ISBN : 9780470867815

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Chiral Pollutants by Imran Ali,Hassan Y. Aboul-Enein Pdf

Today, among the various chiral discrimination methods, chromatography and capillary electrophoresis techniques have become powerful tools in environmental analysis. Therefore, there is a need to describe the art of the determination of the chiral pollutants in the environmental matrices. This book provides the complete information on the types of the chiral pollutants, their toxicities and methods of determination by chromatography and capillary electrophoresis.

Author : Yoshihisa Inoue,V. Ramamurthy
Publisher : CRC Press
Page : 704 pages
File Size : 44,8 Mb
Release : 2004-08-30
Category : Medical
ISBN : 9780203026342

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Chiral Photochemistry by Yoshihisa Inoue,V. Ramamurthy Pdf

Control of molecular chirality is central to contemporary chemistry, biology, and materials-related areas. Chiral photochemistry employs molecular and supramolecular chiral interactions in the electronically excited state to induce molecular chirality, providing new and versatile strategies and surprising results unattainable by conventional therma

Author : Zhiyong Tang
Publisher : John Wiley & Sons
Page : 300 pages
File Size : 54,8 Mb
Release : 2018-03-05
Category : Technology & Engineering
ISBN : 9783527337576

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Chiral Nanomaterials by Zhiyong Tang Pdf

Thorough and up-to-date, this book presents recent developments in this exciting research field. To begin with, the text covers the fabrication of chiral nanomaterials via various synthesis methods, including electron beam lithography, ion beam etching, chemical synthesis and biological DNA directed assembly. This is followed by the relevant theory and reaction mechanisms, with a discussion of the characterization of chiral nanomaterials according to the optical properties of metal nanoparticles, semiconductor nanocrystals, and nanoclusters. The whole is rounded off by a summary of applications in the field of catalysis, sensors, and biomedicine. With its comprehensive yet concise coverage of the whole spectrum of research, this is invaluable reading for senior researchers and entrants to the field of nanoscience and materials science.