Chitosan Based Systems For Biopharmaceuticals

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Chitosan-Based Systems for Biopharmaceuticals

Bruno Sarmento,Jose das Neves
Chitosan Based Systems for Biopharmaceuticals Book PDF

Author : Bruno Sarmento,Jose das Neves
Publisher : John Wiley & Sons
Page : 688 pages
File Size : 46,7 Mb
Release : 2012-02-16
Category : Science
ISBN : 9781119964070

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Chitosan-Based Systems for Biopharmaceuticals by Bruno Sarmento,Jose das Neves Pdf

Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs. Chitosan-Based Systems for Biopharmaceuticals provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential. Topics covered include: chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals physical properties of chitosan and derivatives in sol and gel states absorption promotion properties of chitosan and derivatives biocompatibility and biodegradation of chitosan and derivatives biological and pharmacological activity of chitosan and derivatives biological, chemical and physical compatibility of chitosan and biopharmaceuticals approaches for functional modification or crosslinking of chitosan use of chitosan and derivatives in conventional biopharmaceutical dosage forms manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals chitosan and derivatives for biopharmaceutical use: mucoadhesive properties chitosan-based systems for mucosal delivery of biopharmaceuticals chitosan-based delivery systems for mucosal vaccination chitosan-based nanoparticulates for oral delivery of biopharmaceuticals chitosan-based systems for ocular delivery of biopharmaceuticals chemical modification of chitosan for delivery of DNA and siRNA target-specific chitosan-based nanoparticle systems for nucleic acid delivery functional PEGylated chitosan systems for biopharmaceuticals stimuli-sensitive chitosan-based systems for biopharmaceuticals chitosan copolymers for biopharmaceuticals application of chitosan for anti-cancer biopharmaceutical delivery chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine wound healing properties of chitosan and its use in wound dressing biopharmaceuticals toxicological properties of chitosan and derivatives for biopharmaceutical applications regulatory status of chitosan and derivatives patentability and intellectual property issues quality control and good manufacturing practice preclinical and clinical use of chitosan and derivatives for biopharmaceuticals Chitosan-Based Systems for Biopharmaceuticals is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.

Chitosan for Biomaterials IV

R. Jayakumar,M. Prabaharan
Chitosan for Biomaterials IV Book PDF

Author : R. Jayakumar,M. Prabaharan
Publisher : Springer Nature
Page : 472 pages
File Size : 44,6 Mb
Release : 2021-08-29
Category : Science
ISBN : 9783030830212

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Chitosan for Biomaterials IV by R. Jayakumar,M. Prabaharan Pdf

This volume presents the recent developments on the biomedical applications of chitosan and its derivatives. Chitosan exhibits unique properties such as non-toxicity, biodegradability and biocompatibility. Since its chemical structure and properties can be easily modified, it can be an ideal candidate as a biomaterial. Consequently, chitosan and its derivatives are being developed in different forms such as nanoparticles, micelles, nanofibers, hydrogels, films and 3D porous materials for various biomedical applications, ranging from drug and gene delivery to tissue engineering and regenerative medicine. The chapters of this volume focus on the potential use of chitosan and its derivatives as a hemostatic agent, tissue sealants, tissue engineering scaffolds, delivery carriers for bioactive molecules in bone tissue engineering and wound dressings. Some chapter’s deal with recent advancements of chitosan-based biomaterials as a drug, gene and transdermal drug delivery carrier. In addition, the volume focusses on the prospects of chitosan-based systems for the treatment of cancer, eye and other infectious diseases. The volume will be of interest to material scientists, chemists and biotechnologists by providing a better understanding of the physicochemical and biological characteristics of chitosan and its derivatives to develop more appropriate and innovative chitosan-based materials modified for unlimited practical applications in biomedical fields.

Chitosan-Based Hydrogels

Kangde Yao,Junjie Li,Fanglian Yao,Yuji Yin
Chitosan Based Hydrogels Book PDF

Author : Kangde Yao,Junjie Li,Fanglian Yao,Yuji Yin
Publisher : CRC Press
Page : 492 pages
File Size : 53,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439821152

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Chitosan-Based Hydrogels by Kangde Yao,Junjie Li,Fanglian Yao,Yuji Yin Pdf

Due to their unique properties, chitosan-based materials have emerged as useful resources in a variety of medicines, drug controlled-release carriers, tissue engineering scaffolds, and immobilized enzymes. But many of these materials have yet to reach the commercial market. Therefore, more work must be completed to fill the gap between research and

Chitosan Based Biomaterials Volume 2

Jessica Amber Jennings,Joel David Bumgardner
Chitosan Based Biomaterials Volume 2 Book PDF

Author : Jessica Amber Jennings,Joel David Bumgardner
Publisher : Woodhead Publishing
Page : 296 pages
File Size : 47,7 Mb
Release : 2016-09-28
Category : Technology & Engineering
ISBN : 9780081002568

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Chitosan Based Biomaterials Volume 2 by Jessica Amber Jennings,Joel David Bumgardner Pdf

Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials. Presents specific focus on tissue engineering and therapeutics Provides comprehensive treatment of all biomaterial applications of chitosan Contains contributions by leading researchers with extensive experience in the material

Chitosan in Biomedical Applications

Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Chitosan in Biomedical Applications Book PDF

Author : Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak
Publisher : Academic Press
Page : 428 pages
File Size : 40,6 Mb
Release : 2021-12-01
Category : Technology & Engineering
ISBN : 9780128212448

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Chitosan in Biomedical Applications by Md Saquib Hasnain,Sarwar Beg,Amit Kumar Nayak Pdf

Chitosan in Biomedical Applications provides a thorough insight into the complete chitosan chemistry, collection, chemical modifications, characterization and applications of chitosan in biomedical applications and healthcare fields. Chitosan, a biopolymer of natural origin, has been explored for its variety of applications in biomedical research, medical diagnostic aids and material science. It is the second most abundant natural biopolymer after cellulose, and considered as an excellent excipient because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of chitosan in biomedical applications. The book explores key topics, such as molecular weight, degree of deacetylation, and molecular geometry, along with an emphasis on recent advances in the field written by academic, industry, and clinical researchers. Chitosan in Biomedical Applications will be of interest to those in biomedical fields including the biomaterials and tissue engineering community investigating and developing biomaterials for biomedical applications, particularly graduate students, young faculty and others exploring chitosan-based materials. Provides methodology for the design, development and selection of chitosan in biomedical applications for particular therapeutic applications Includes illustrations demonstrating the mechanism of biological interaction of chitosan Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan

Chitosan

Shakeel Ahmed,Saiqa Ikram
Chitosan Book PDF

Author : Shakeel Ahmed,Saiqa Ikram
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 49,6 Mb
Release : 2017-09-14
Category : Technology & Engineering
ISBN : 9781119364801

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Chitosan by Shakeel Ahmed,Saiqa Ikram Pdf

This book delves deeply in to the preparation, characterization and multiple applications of chitin and chitosan. The 17 chapters written by leading experts is an excellent reference source and state-of-the-art review for researchers and scientists using chitosan or biopolymers in their respective areas. This book is divided into following sections: • Production and derivatives of chitosan • Chitosan in the textile and food industries • Chitosan in biomedical applications • Chitosan in agriculture and water treatment The book is practical as readers will be able to see descriptions of chitosan production methods as well as techniques that can be used to estimate and modify their physical and chemical properties. It provides a full description not only of the traditional and recent developments in the applications of chitosan in the fields of biotechnology, environmental studies, food, medicine, water treatments, drug delivery, but it includes all of the therapeutically usages as well.

Chitosan for Biomaterials IV

R. Jayakumar,M. Prabaharan
Chitosan for Biomaterials IV Book PDF

Author : R. Jayakumar,M. Prabaharan
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2021
Category : Electronic
ISBN : 3030830225

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Chitosan for Biomaterials IV by R. Jayakumar,M. Prabaharan Pdf

This volume presents the recent developments on the biomedical applications of chitosan and its derivatives. Chitosan exhibits unique properties such as non-toxicity, biodegradability and biocompatibility. Since its chemical structure and properties can be easily modified, it can be an ideal candidate as a biomaterial. Consequently, chitosan and its derivatives are being developed in different forms such as nanoparticles, micelles, nanofibers, hydrogels, films and 3D porous materials for various biomedical applications, ranging from drug and gene delivery to tissue engineering and regenerative medicine. The chapters of this volume focus on the potential use of chitosan and its derivatives as a hemostatic agent, tissue sealants, tissue engineering scaffolds, delivery carriers for bioactive molecules in bone tissue engineering and wound dressings. Some chapter's deal with recent advancements of chitosan-based biomaterials as a drug, gene and transdermal drug delivery carrier. In addition, the volume focusses on the prospects of chitosan-based systems for the treatment of cancer, eye and other infectious diseases. The volume will be of interest to material scientists, chemists and biotechnologists by providing a better understanding of the physicochemical and biological characteristics of chitosan and its derivatives to develop more appropriate and innovative chitosan-based materials modified for unlimited practical applications in biomedical fields.

Functional Chitosan

Sougata Jana,Subrata Jana
Functional Chitosan Book PDF

Author : Sougata Jana,Subrata Jana
Publisher : Springer Nature
Page : 489 pages
File Size : 42,5 Mb
Release : 2020-03-05
Category : Medical
ISBN : 9789811502637

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Functional Chitosan by Sougata Jana,Subrata Jana Pdf

Thanks to their unique properties, chitosan and chitosan-based materials have numerous applications in the field of biomedicine, especially in drug delivery. This book examines biomedical applications of functional chitosan, exploring the various functions and applications in the development of chitosan-based biomaterials. It also describes the chemical structure of chitosan and discusses the relationship between their structure and functions, providing a theoretical basis for the design of biomaterials. Lastly, it reviews chemically modified and composite materials of chitin and chitosan derivatives for biomedical applications, such as tissue engineering, nanomedicine, drug delivery, and gene delivery.

Chitosan Based Materials and its Applications

Sergio Paulo Campana-Filho,Luiz Antonio de Almeida Pinto
Chitosan Based Materials and its Applications Book PDF

Author : Sergio Paulo Campana-Filho,Luiz Antonio de Almeida Pinto
Publisher : Bentham Science Publishers
Page : 334 pages
File Size : 45,9 Mb
Release : 2017-06-07
Category : Technology & Engineering
ISBN : 9781681084855

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Chitosan Based Materials and its Applications by Sergio Paulo Campana-Filho,Luiz Antonio de Almeida Pinto Pdf

This volume presents 10 reviews contributed by eminent researchers around the world on chitosan based materials. The introductory chapters present information on general characteristics of chitosan and various types of materials which are based on it such as nanofibers, nanoparticles, nanocapsules and other chemically modified chitosans. This is followed by an explanation of chitosan characterization and extraction techniques. Concluding chapters describe the applications of chitosan products in water treatment, drug delivery, edible films and pervaporation membranes. Readers will therefore gain an understanding about chitosan and materials derived from this polymer and their practical applications. The volume serves as a simple reference for chemical engineering students and professionals interested in the basic and applied chemistry of chitosan and chitosan-derived products.

Chitosan and Its Derivatives as Promising Drug Delivery Carriers

M. Prabaharan
Chitosan and Its Derivatives as Promising Drug Delivery Carriers Book PDF

Author : M. Prabaharan
Publisher : Momentum Press
Page : 84 pages
File Size : 47,5 Mb
Release : 2012-10-19
Category : Technology & Engineering
ISBN : 9781606504130

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Chitosan and Its Derivatives as Promising Drug Delivery Carriers by M. Prabaharan Pdf

Chitosan, a natural based polymer obtained by alkaline deacetylation of chitin, is non-toxic, biocompatible, and biodegradable. These properties make chitosan a good candidate for the development of conventional and novel drug delivery systems. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve its solubility and widen its applications. Chemical modification of chitosan is useful for the association of bioactive molecules to the polymer and controlling the drug release profile. Chemical modification will introduce desired properties and enlarge the field of the potential applications of chitosan with the choice of various types of side chains. In this monograph, recent studies on the various types of chitosan microspheres are discussed from the viewpoint of drug delivery applications. Moreover, different types of chitosan derivatives developed as controlled drug delivery carriers and their preparation methods are discussed in detail. The modifications discussed here include amphiphilic chitosan derivatives, N-(aminoalkyl) chitosan, carboxymethyl chitosan, thiolated chitosans, phosphorylated chitosan, etc. Special emphasis has been given to the development of chitosan-based polyelectrolyte complexes, graft copolymerized chitosan and chitosan-based stimuli-responsive hydrogels as drug delivery carriers. The reviewed studies lead to the conclusion that chitosan derivatives are promising materials for the controlled delivery of various types of therapeutic agents.

Chitosan for Biomaterials I

R. Jayakumar,M. Prabaharan,Riccardo A. A. Muzzarelli
Chitosan for Biomaterials I Book PDF

Author : R. Jayakumar,M. Prabaharan,Riccardo A. A. Muzzarelli
Publisher : Springer
Page : 236 pages
File Size : 47,5 Mb
Release : 2011-08-10
Category : Technology & Engineering
ISBN : 3642231152

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Chitosan for Biomaterials I by R. Jayakumar,M. Prabaharan,Riccardo A. A. Muzzarelli Pdf

Polymeric Nanoparticles of Chitosan Derivatives as DNA and siRNA Carriers, by Y. K. Kim, H. L. Jiang, Y. J. Choi, I. K. Park, M. H. Cho and C. S. Cho.- Chitosan and Its Derivatives for Drug Delivery Perspective, by T. A. Sonia and C. P. Sharma.- Chitosan-based Nanoparticles in Cancer Therapy, by V.-K. Lakshmanan, K. S. Snima, J. D. Bumgardner, S. V. Nair, and R. Jayakumar.- Chitosan and Thiolated Chitosan, by F. Sarti and A. Bernkop-Schnürch.- Chitosan-Based Particulate Systems for Non-Invasive Vaccine Delivery, by S. Şenel.- Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy, by J. Y. Yhee, Heebeom Koo, Dong Eun Lee, Kuiwon Choi, Ick Chan Kwon and Kwangmeyung Kim.- Chitosan-Coated Iron Oxide Nanoparticles for Molecular Imaging and Drug Delivery, by H. Arami, Z. Stephen, O. Veiseh and M. Zhang.- Chitosan: Its Applications in Drug-Eluting Devices, by Mei -Chin Chen, Fwu -Long Mi, Zi -Xian Liao and Hsing -Wen Sung.-

Chitosan, Chitosan Derivatives and Their Applications

Agnieszka Ewa Wiącek
Chitosan Chitosan Derivatives and Their Applications Book PDF

Author : Agnieszka Ewa Wiącek
Publisher : Unknown
Page : 0 pages
File Size : 45,8 Mb
Release : 2024-02-23
Category : Science
ISBN : 3725802548

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Chitosan, Chitosan Derivatives and Their Applications by Agnieszka Ewa Wiącek Pdf

"Chitosan, Chitosan Derivatives and Their Applications" is devoted to the latest advances in research on chitosan-based systems and focuses on highlighting scientific discoveries carried out in leading laboratories around the world. This topic is a developing field of science, but a very promising one in terms of practical applications. The manuscripts included in this book focus on all aspects of the production, modification, enzymology and application of chitin/chitosan-based systems. The reprint is divided into two parts, each of which begins with an overview article. The first half of the collected articles concerns with the application potential in agricultural and nutritional sciences. The second part covers medical and pharmaceutical applications. At the end of the presented series, several articles devoted to the synthesis and characterization of chitosan-based materials were collected. All mentioned articles (21 in total) represent a high scientific level and the latest trends in research on chitin, chitosan and their derivatives. I wish you a pleasant read.

Mucosal Delivery of Biopharmaceuticals

José das Neves,Bruno Sarmento
Mucosal Delivery of Biopharmaceuticals Book PDF

Author : José das Neves,Bruno Sarmento
Publisher : Springer Science & Business Media
Page : 603 pages
File Size : 55,5 Mb
Release : 2014-02-03
Category : Medical
ISBN : 9781461495246

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Mucosal Delivery of Biopharmaceuticals by José das Neves,Bruno Sarmento Pdf

Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing biopharmaceuticals for mucosal delivery, with a focus on the most successful case studies of recent years. The last section briefly centers on relevant aspects of the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals.​ Scientists and researchers in the fields of drug delivery, material science, biomedical science and bioengineering as well as professionals, regulators and policy makers in the pharmaceutical, biotechnology and healthcare industries will find in this book an important compendium of fundamental concepts and practical tools for their daily research and activities.

Chitosan Based Nanomaterials in Plant Growth and Protection

Vinod Saharan,Ajay Pal
Chitosan Based Nanomaterials in Plant Growth and Protection Book PDF

Author : Vinod Saharan,Ajay Pal
Publisher : Springer
Page : 55 pages
File Size : 46,5 Mb
Release : 2016-07-13
Category : Science
ISBN : 9788132236016

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Chitosan Based Nanomaterials in Plant Growth and Protection by Vinod Saharan,Ajay Pal Pdf

This brief describes various methods of chitosan nano-materials synthesis, with detailed discussion of various factors effecting its synthesis process, stability and physicochemical properties. Chitosan is naturally occurring biopolymer derived from chitin. Due to the unique biological properties of chitosan nano-materials such as antimicrobial, plant growth inducer, plant defense modulator, chitosan has gained attention in fields of plant sciences. Book further extended the details of different types of chitosan nano-materials specially for plant applications along with its future prospects in plant protection and growth. Bioactivities of chitosan nano-materials and its mechanism have also been covered. This book aims to widening the understanding of the synthesis, characterization and use of chitosan based nano-materials in plant system.

Chitosan Based Biomaterials Volume 1

Jessica Amber Jennings,Joel David Bumgardner
Chitosan Based Biomaterials Volume 1 Book PDF

Author : Jessica Amber Jennings,Joel David Bumgardner
Publisher : Woodhead Publishing
Page : 342 pages
File Size : 44,9 Mb
Release : 2016-09-26
Category : Technology & Engineering
ISBN : 9780081002575

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Chitosan Based Biomaterials Volume 1 by Jessica Amber Jennings,Joel David Bumgardner Pdf

Chitosan Based Biomaterials: Fundamentals, Volume 1, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book looks at the fundamentals of chitosan-based biomaterials. Contains specific focus on the techniques and technologies needed to develop chitosan for biomedical applications Presents a comprehensive treatment of the fundamentals Provides contributions from leading researchers with extensive experience in chitosan