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Author : Anonim
Publisher : Elsevier
Page : 461 pages
File Size : 52,9 Mb
Release : 1993-09-09
Category : Medical
ISBN : 9780080862231
Cholinergic Function and Dysfunction
Author : A. Claudio Cuello
Publisher : Unknown
Page : 0 pages
File Size : 40,8 Mb
Release : 1993
Category : Cholinergic mechanisms
ISBN : 0444801049
Author : Man Singh
Publisher : Springer Science & Business Media
Page : 544 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468412185
Although serious interest in studying the role of central cho linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior. reiations is quite extensive. During the past thirty years, cholinergic research has contributed significantly to the characterization and differentiation of adaptive mechanisms in volved in input selection, perception, cortical, autonomic and behav ioral activation, learning, memory, and inhibitory control of behav ioral outputs. To say that dysfunction of one or more of these mech anisms may be at the root of neuropsychiatric illnesses such as schiz ophrenia would be stating the obvious. This book examines the part cholinergic processes might play in dysfunctions of the adaptive processes involved in higher brain func tions and their significance for the pathogenesis, classification, etiology, and treatment of psychopathological conditions. In a series of wide ranging reviews of the available information, the subject is discussed from a variety of perspectives, using data derived from both experimental and clinical research. The purpose is not so much to determine whether cholinergic excess or deficiency is causal in this or that neuropsychiatric syndrome, but rather to try to understand the disease mechanisms in terms of adaptive processes in which cholinergic systems seem to play an important part.
Author : D. Jenden
Publisher : Springer Science & Business Media
Page : 867 pages
File Size : 44,6 Mb
Release : 2013-03-13
Category : Psychology
ISBN : 9781468430967
This volume represents a collection of papers which were contributed by participants at a Symposium for Cholinergic Mechanisms and Psycho pharmacology, held in La Jolla, California on March 28-30, 1977. The were chosen to emphasize areas in which there has been substantial topics progress in the past 2-3 years and fall into seven major groups dealingwith: cholinergiC receptors; chemistry, histochemistry and enzymology; cyclic nucleotides and cholinergiC mechanisms; storage, compartmentation and release of acetylcholine; regulatory mechanisms in acetylcholine metab olism; modulation of acetylcholine metabolism; and behavioral and clin ical manifestations of cholinergiC function and dysfunction. Each group contains one or more reviews and a number of shorter contributions de scribing current work. This symposium was the third in a series of which the first two were held in Skokloster, Sweden in 1970 and Boldern, Switzerland in 1974. The Proceedings of the meetings indicate a rapid development of knowledge of cholinergiC mechanisms which for many years lagged behind that of other neurotransmitters and neuroregulators. The inclusion of a large section in the present volume dealing with clinical manifestations of cholinergiC dysfunction reflects one of the most important trends in current research on cholinergiC mechanisms, namely the close inter-relationship and mutual support of basic science and clinical investigation. I hope that this volume will be of value to all those whose work relates to cholinergiC function, at both basic and clinicalleve18, and will continue to stimulate the vigorous exchange of ideas which was such a prominent feature of the Symposium.
Author : Edward D. Levin
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 41,8 Mb
Release : 2006-11-18
Category : Medical
ISBN : 9783764377724
This book gathers cutting edge research on how transmitter interactions form the mechanistic bases for attention, learning and memory. The research provides a more accurate, though complex, picture of how the brain provides cognitive function, and offers new understanding about the mechanisms of cognitive dysfunction and novel avenues for therapeutic treatment. The contributors review their latest findings, and point out directions of advancement of the field of neurotransmitter interactions and cognitive function.
Author : Edward D. Levin,Jerry J. Buccafusco
Publisher : CRC Press
Page : 395 pages
File Size : 40,5 Mb
Release : 2006-06-22
Category : Medical
ISBN : 9781420004335
The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen
Author : Federico Bermudez-Rattoni
Publisher : CRC Press
Page : 368 pages
File Size : 42,6 Mb
Release : 2007-04-17
Category : Psychology
ISBN : 9781420008418
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Author : J. Klein,K. Löffelholz
Publisher : Elsevier
Page : 376 pages
File Size : 45,6 Mb
Release : 1996-12-18
Category : Science
ISBN : 9780080862347
This volume offers a comprehensive update and overview of the field of cholinergic transmission as presented by some thirty distinguished investigators who were recruited for their task from Germany, Great Britain, Canada, USA, Sweden, Israel, France and Italy. Exciting new discoveries, described in this volume, are due to recent methodological breakthroughs. These discoveries throw new light on many areas of cholinergic mechanisms.
Author : Mohammed Shoaib,Tanya L. Wallace
Publisher : Springer Nature
Page : 245 pages
File Size : 45,9 Mb
Release : 2020-08-29
Category : Medical
ISBN : 9783030560133
The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
Author : Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publisher : National Academies Press
Page : 444 pages
File Size : 43,6 Mb
Release : 2011-07-01
Category : Medical
ISBN : 9780309210089
Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Author : Jerry J. Buccafusco
Publisher : CRC Press
Page : 341 pages
File Size : 54,8 Mb
Release : 2000-08-29
Category : Medical
ISBN : 9781420041811
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author : H. Yokozeki,H. Murota,I. Katayama
Publisher : Karger Medical and Scientific Publishers
Page : 124 pages
File Size : 45,7 Mb
Release : 2016-09-01
Category : Medical
ISBN : 9783318059052
Research into perspiration has developed dramatically during the last 15 years, continually improving our understanding of the pathogenesis of sweating disorders. It has become clear that, in addition to its temperature-regulating function, perspiration offers bactericidal protection as well. In this book, select authors further broaden our perspective on perspiration. Contributions cover a variety of new aspects, offering insight into the sweat glands' major role during the onset of disorders such as parapsoriasis, lichen planus, and lichen amyloidosis. They also highlight the importance of Malassezia - an allergen in sweat that exacerbates atopic dermatitis and cholinergic urticarial. Further roles of the sweat glands are discussed, including as storage of stem cells for replenishing epidermal cells in the case of thermal burns or as water retention sites for replenishing moisture in the stratum corneum. In addition, a novel analysis of the sweat glands' three-dimensional structures, using high-speed en-face optical coherence tomography (OCT), is introduced. Offering an in-depth overview of the latest knowledge in perspiration research, this book serves as an essential reference for all medical staff and researchers in the field.
Author : Alexander G. Karczmar
Publisher : Springer Science & Business Media
Page : 698 pages
File Size : 41,8 Mb
Release : 2007-04-05
Category : Science
ISBN : 9780387465265
Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Author : Massimo Avoli,Tomas A. Reader,Robert W. Dykes,Pierre Gloor
Publisher : Springer Science & Business Media
Page : 610 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309253
Herbert Henri Jasper is a scientist whose research activities have initiated and encompassed many of the major themes of neuroscience. He has pioneered in single unit recording, chronic neuronal studies, neurochemistry, electroencephalography, and many other disciplines. His students now hold important positions in universities and hospitals around the world. From July 21 to 23, 1986, a symposium entitled Neurotransmitters and Cortical Function: From Molecules to Mind was held in Montreal to honor Professor Jasper and to continue his pioneering efforts. The following chapters originated in that meeting. They summarize the current v vi PREFACE status of our knowledge in some of the fields influenced by Professor Jasper. They share a focus on neurotransmitters in cortical function, where we presume higher mental events originate. Professor Jasper has made contributions to the understanding of three different classes of neuro transmitters: GABA, acetylcholine, and catecholamines. It is an interest in trying to link neu rochemical events to some aspects of complex brain function and behavior that has characterized his work, and it is this philosophy that led to the present symposium to honor him. We dedicate this volume to Professor Jasper and the integrative approach that he has fostered. The Editors Montreal Contents 1. H. H. Jasper, Neuroscientist of Our Century .......................... .
Author : K.P. Ebmeier,J.T. O'Brien,J.-P. Taylor
Publisher : Karger Medical and Scientific Publishers
Page : 160 pages
File Size : 41,5 Mb
Release : 2012-01-06
Category : Medical
ISBN : 9783805598019
Psychiatric symptoms are common in the neurological and geriatric care of patients with Parkinson’s disease. This book assembles short reviews from experts in the field to chart the various psychiatric syndromes known in Parkinson’s disease, their presentation, etiology and management. Presented are special topics on epidemiology of psychiatric symptoms, affective disorders and apathy, early cognitive impairment through to dementia, visuoperceptual dysfunction, psychotic disorders, sleep disturbances, impulse disorders and sexual problems. Further, rarely discussed issues, such as the relationship between somatoform disorders and parkinsonism are reviewed. This publication is essential reading for old age psychiatrists, gerontologists and neurologists who work with patients suffering from Parkinson’s disease. In addition, health practitioners who deal with senior patients, as well as scientists who need a quick update on the progress in this important clinical field will find this volume a helpful reference.
