Circadian Rhythms And Health Research Trends

Author : Alfredo V. Lignelli
Publisher : Nova Science Publishers
Page : 244 pages
File Size : 45,9 Mb
Release : 2007
Category : Medical
ISBN : STANFORD:36105124045266

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Circadian Rhythms and Health Research Trends by Alfredo V. Lignelli Pdf

A circadian rhythm is a roughly-24-hour cycle in the physiological processes of living beings, including plants, animals, fungi and cyanobacteria. The term 'circadian', comes from the Latin circa, 'around', and dies, 'day', meaning literally 'about a day'. The formal study of biological temporal rhythms such as daily, weekly, seasonal, and annual rhythms, is called chronobiology. In a strict sense, circadian rhythms are endogenously generated, although they can be modulated by external cues such as sunlight and temperature. Most of a person's body systems demonstrate circadian variations. The body systems with the most prominent circadian variations are the sleep-wake cycle, the temperature regulation system, and the endocrine system. The malfunctioning of a person's circadian system, or biological clock, causes circadian rhythm disorders. Circadian rhythms and their relation to health outcomes in the globalised hyper world of the 21st century are now understood to be extremely important.

Author : Rajeshwar P. Sinha
Publisher : Nova Science Publishers
Page : 365 pages
File Size : 42,7 Mb
Release : 2022
Category : Technology & Engineering
ISBN : 1685075851

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Circadian Rhythms and Their Importance by Rajeshwar P. Sinha Pdf

"Circadian rhythm is the mechanism for measuring time by organisms in units of around 24 hours. Almost every organism has the ability to predict daily events such as sunrise and sunset, which is essential for their optimal survival strategies. Circadian rhythms persist even in the absence of time cues and ensure that behavioral, physiological and metabolic processes align with changing environmental conditions. Most organisms, irrespective of whether they are prokaryotic or eukaryotic, have evolved certain mechanisms to sense their external environment in order to prepare a biological response. Often, these biological responses result in changes in physiology and biochemistry of organisms for the optimization of their survival. There is no unified mechanism among organisms by which sensory environment can be applied to control their lifespan. In humans, disruptions of the circadian rhythm may have an increased risk of age-related neurodegenerative diseases such as cancer, diabetes, etc. This book encompasses the most recent knowledge and modern trends in the field of circadian rhythms research. It is also expected to provide a must-read guide for beginners as well as advanced researchers in this field of study. Undergraduate, post-graduate and research scholars of several disciplines such as chemistry, botany, microbiology, biochemistry, biotechnology, bioinformatics, life sciences and bionanotechnology will benefit from this book"--

Author : Guangrui Yang,Han Wang,Erquan Zhang
Publisher : Frontiers Media SA
Page : 98 pages
File Size : 49,6 Mb
Release : 2015-10-12
Category : Circadian rhythms
ISBN : 9782889196654

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Therapeutic Implications of Circadian Rhythms by Guangrui Yang,Han Wang,Erquan Zhang Pdf

Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, the core clock genes are rhythmically expressed in both the suprachiasmatic nucleus (SCN), the master clock residing in the hypothalamus, and almost all peripheral tissues where they control numerous target genes in a circadian manner, and thus affect many physiological and biochemical processes. Evidence suggests that disruption of the circadian rhythms (or desynchronization) is a significant risk factor for the development of metabolic diseases, cardiovascular diseases, cancer and sleep disorders. Evidence also suggests that the disruption suppresses immune function and increases vulnerability to infectious diseases. Restoring or strengthening the circadian rhythm may be therapeutic for these conditions. This becomes exceptionally important in modern societies because many people are suffering from frequent desynchronization due to shift working, exposure to artificial light, travel by transmeridian air flight, and involvement in social activities. Besides, the temporal variations in the incidence and severity of many diseases, such as the onset of cardiovascular events, chronic obstructive pulmonary disease (COPD), inflammatory diseases and mental disorders have also drawn increasing attention to the circadian clock. The circadian rhythms affect not only the health status, but also the drug efficiency. The effects (and side effects) of many drugs vary with biological timing. The tolerance of many medications displays circadian variation as well. The timing of medical treatment in coordination with the body clock may significantly increase the desired effects of drugs, and lower the dose and toxicity. In addition, circadian rhythms can also be modulated by some therapeutic drugs, for example, melatonin and modafinil, which are used to treat circadian rhythm sleep disorders. In this Research Topic, we assemble a series of critical review and research articles that focus on the therapeutic implications of circadian rhythms. Topics include, but are not limited to: • Circadian disruption caused diseases or disorders and related intervention • Temporal manifestation of diseases or disorders and therapeutic implications • The effects of circadian rhythms on drugs • The effects of drugs on circadian rhythms

Author : Mohamed A. El-Esawi
Publisher : BoD – Books on Demand
Page : 168 pages
File Size : 45,9 Mb
Release : 2018-07-04
Category : Medical
ISBN : 9781789233384

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Circadian Rhythm by Mohamed A. El-Esawi Pdf

Circadian clocks are endogenous and temperature-compensating timekeepers that provide temporal organization of biological processes in living organisms. Circadian rhythms allow living organisms to adapt to the daily light cycles associated with Earth's rotation and to anticipate and prepare for precise and regular environmental changes. This book discusses the fundamental advances of how the circadian clock regulates critical biological functions as well as the cellular and molecular mechanisms controlling circadian rhythm in living organisms. It also provides new insights into and sheds new light on the current research trends and future research directions related to circadian rhythm. This book provokes interest in many readers, researchers and scientists, who can find this information useful for the advancement of their research works towards a better understanding of circadian rhythm regulatory mechanisms.

Author : Frank H. Columbus
Publisher : Nova Publishers
Page : 238 pages
File Size : 55,7 Mb
Release : 2006
Category : Chronobiology
ISBN : 1594544824

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Trends in Chronobiology Research by Frank H. Columbus Pdf

This book covers topics from a wide variety of disciplines including cell biology, developmental biology, ecology, endocrinology, genetics, molecular biology, neurobiology, and pharmacology. There is a focus on circadian (daily), tidal, seasonal, and annual rhythms, as well as other biological rhythms. Rhythms are placed within the context of the functional significance of these rhythms for the health and well-being of relevant organisms and include genetic and molecular mechanisms of biological timekeeping, melatonin and pineal gland rhythms, as well as on the chronobiology and chronotherapy of cardiovascular, pulmonary, ulcer, and other diseases.

Author : Michelle L. Gumz
Publisher : Springer
Page : 378 pages
File Size : 42,8 Mb
Release : 2016-02-29
Category : Medical
ISBN : 9781493934508

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Circadian Clocks: Role in Health and Disease by Michelle L. Gumz Pdf

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.

Author : Charles A. Czeisler
Publisher : Unknown
Page : 692 pages
File Size : 45,6 Mb
Release : 1978
Category : Human physiology
ISBN : OCLC:84039346

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Human Circadian Physiology by Charles A. Czeisler Pdf

Author : Mohamed El-Esawi
Publisher : Unknown
Page : 156 pages
File Size : 55,6 Mb
Release : 2018
Category : Adrenal glands
ISBN : 1789233399

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Circadian Rhythm by Mohamed El-Esawi Pdf

Author : Christopher S. Colwell
Publisher : John Wiley & Sons
Page : 405 pages
File Size : 40,8 Mb
Release : 2015-07-07
Category : Medical
ISBN : 9781118467787

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Circadian Medicine by Christopher S. Colwell Pdf

Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.

Author : Arturo Ortega,Mario Caba,Pevet Paul
Publisher : Frontiers Media SA
Page : 105 pages
File Size : 44,5 Mb
Release : 2020-11-19
Category : Science
ISBN : 9782889661312

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Disorders of Circadian Rhythms by Arturo Ortega,Mario Caba,Pevet Paul Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author : Meir H. Kryger,Thomas Roth,William C. Dement
Publisher : Elsevier Health Sciences
Page : 1804 pages
File Size : 40,7 Mb
Release : 2010-11-01
Category : Health & Fitness
ISBN : 9781437736090

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Principles and Practice of Sleep Medicine - E-Book by Meir H. Kryger,Thomas Roth,William C. Dement Pdf

Principles and Practice of Sleep Medicine, 5th Edition, by Meir H. Kryger, MD, FRCPC, Thomas Roth, PhD, and William C. Dement, MD, PhD, delivers the comprehensive, dependable guidance you need to effectively diagnose and manage even the most challenging sleep disorders. Updates to genetics and circadian rhythms, occupational health, sleep in older people, memory and sleep, physical examination of the patient, comorbid insomnias, and much more keep you current on the newest areas of the field. A greater emphasis on evidence-based approaches helps you make the most well-informed clinical decisions. And, a new more user-friendly, full-color format, both in print and online, lets you find the answers you need more quickly and easily. Whether you are preparing for the new sleep medicine fellowship examination, or simply want to offer your patients today's best care, this is the one resource to use! Make optimal use of the newest scientific discoveries and clinical approaches that are advancing the diagnosis and management of sleep disorders.

Author : S. Michal Jazwinski,Victoria P Belancio,Steven M Hill
Publisher : Springer
Page : 361 pages
File Size : 45,9 Mb
Release : 2017-10-24
Category : Medical
ISBN : 9783319645438

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Circadian Rhythms and Their Impact on Aging by S. Michal Jazwinski,Victoria P Belancio,Steven M Hill Pdf

Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

Author : R.A. Wever
Publisher : Springer Science & Business Media
Page : 285 pages
File Size : 54,9 Mb
Release : 2013-03-07
Category : Medical
ISBN : 9781461261421

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The Circadian System of Man by R.A. Wever Pdf

Biological rhythmicity has been a subject of scientific research for a relatively short time. In the special case of daily, or circadian rhythms, it is only during the past twenty years that rapidly increasing efforts have been undertaken in evaluat ing properties and mechanisms. As a consequence of these efforts, the study of biological and, in particular, circadian rhythmicity is no longer a somewhat dubious occupation but rather a serious branch of science which combines the interdisciplinary efforts of numerous researchers around the world. The general result of these efforts is that many features of circadian rhythms of many different species of living beings are well known today. In addition to studies with lower organisms, the evaluation of human circadian rhythms was originally more or less a compulsory exercise done in order to extend the "catalogue of species"; of course, the work was of unusual impor tance due to the special position of man in biology. In the course of the very first experimental series, it became clear that humans possess an "internal clock" as had been established in various organisms, protists, plants, and animals, and that human circadian rhythms fit the general regularities of biological rhythms known at that time. However, it soon became apparent that circadian rhythmicity of man shows, additionally, particularities of great general interest, for practical and theoretical reasons.

Author : Luka Golovkin
Publisher : Nova Biomedical Books
Page : 0 pages
File Size : 43,7 Mb
Release : 2012
Category : Circadian rhythms
ISBN : 161324858X

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Circadian Rhythms by Luka Golovkin Pdf

"A circadian rhythm is an endogenously driven roughly 24-hour cycle in biochemical, physiological or behavioural processes. Circadian rhythms have been widely observed, in plants, animals, fungi and cyanobacteria. This book presents current research from across the globe in the study of the biology, cognition and disorders associated with circadian rhythms. Topics discussed include circadian clocks and eating disorders; disruption of circadian rhythms in hypersomnia, insomnia and sleep movement disorders; circadian pacemaker in ovary and uterus during cell differentiation and apoptosis and emerging functions of heme in transcription associated with circadian rhythms."--Publisher.

Author : Michelle L. Gumz
Publisher : Springer
Page : 378 pages
File Size : 51,7 Mb
Release : 2018-04-07
Category : Medical
ISBN : 1493980548

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Circadian Clocks: Role in Health and Disease by Michelle L. Gumz Pdf

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.