Circulation

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The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
Page : 82 pages
File Size : 42,9 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9781615047239

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The Cerebral Circulation by Marilyn J. Cipolla Pdf

This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

The Ocular Circulation

Author : Jeffrey W. Kiel
Publisher : Biota Publishing
Page : 83 pages
File Size : 55,8 Mb
Release : 2011-02-01
Category : Medical
ISBN : 9781615041695

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The Ocular Circulation by Jeffrey W. Kiel Pdf

This presentation describes the unique anatomy and physiology of the vascular beds that serve the eye. The needs for an unobstructed light path from the cornea to the retina and a relatively fixed corneal curvature and distance between refractive structures pose significant challenges for the vasculature to provide nutrients and remove metabolic waste. To meet these needs, the ocular vascular beds are confined to the periphery of the posterior two thirds of the eye and a surrogate circulation provides a continuous flow of aqueous humor to nourish the avascular cornea, lens and vitreous compartment. The production of aqueous humor (and its ease of egress from the eye) also generates the intraocular pressure (IOP), which maintains the shape of the eye. However, the IOP also exerts a compressing force on the ocular blood vessels that is higher than elsewhere in the body. This is particularly true for the intraocular veins, which must have a pressure higher than IOP to remain patent, and so the IOP is the effective venous pressure for the intraocular vascular beds. Consequently, the ocular circulation operates at a lower perfusion pressure gradient than elsewhere in the body and is more at risk for ischemic damage when faced with low arterial pressure, particularly if IOP is elevated. This risk and the specialized tissues of the eye give rise to the fascinating physiology of the ocular circulations.

Circulation

Author : François Brunet
Publisher : Terra Foundation for the Arts
Page : 0 pages
File Size : 41,9 Mb
Release : 2017
Category : ART
ISBN : 0932171613

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Circulation by François Brunet Pdf

As a category in art history, circulation is rooted in the contemporary context of Internet culture and the digital image. Yet circulation, as a broader concept for the movement of art across time and space in vastly different cultural and media contexts, has been a factor in the history of the arts in the United States since at least the eighteenth century. The third volume in the Terra Foundation Essays series, Circulation brings together an international and interdisciplinary team of scholars, including Thierry Gervais, Tom Gunning, J. M. Mancini, Frank Mehring, and Hélène Valance, who map the multiple planes where artistic meaning has been produced by the circulation of art from the eighteenth century to the present. The book looks at both broad historical trends and the successes and failures of particular works of art from a wide variety of artists and styles. Together, the contributions significantly expand the conceptual and methodological terrain of scholarship on American art.

Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 46,6 Mb
Release : 2016-08-18
Category : Medical
ISBN : 9781615047215

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Regulation of Tissue Oxygenation, Second Edition by Roland N. Pittman Pdf

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Circulation and Control

Author : Marie-Stéphanie Delamaire,Will Slauter
Publisher : Open Book Publishers
Page : 334 pages
File Size : 47,8 Mb
Release : 2021-10-08
Category : Law
ISBN : 9781800641495

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Circulation and Control by Marie-Stéphanie Delamaire,Will Slauter Pdf

The nineteenth century witnessed a series of revolutions in the production and circulation of images. From lithographs and engraved reproductions of paintings to daguerreotypes, stereoscopic views, and mass-produced sculptures, works of visual art became available in a wider range of media than ever before. But the circulation and reproduction of artworks also raised new questions about the legal rights of painters, sculptors, engravers, photographers, architects, collectors, publishers, and subjects of representation (such as sitters in paintings or photographs). Copyright and patent laws tussled with informal cultural norms and business strategies as individuals and groups attempted to exert some degree of control over these visual creations. With contributions by art historians, legal scholars, historians of publishing, and specialists of painting, photography, sculpture, and graphic arts, this rich collection of essays explores the relationship between intellectual property laws and the cultural, economic, and technological factors that transformed the pictorial landscape during the nineteenth century. This book will be valuable reading for historians of art and visual culture; legal scholars who work on the history of copyright and patent law; and literary scholars and historians who work in the field of book history. It will also resonate with anyone interested in current debates about the circulation and control of images in our digital age.

The Gastrointestinal Circulation

Author : Peter R. Kvietys
Publisher : Morgan & Claypool Publishers
Page : 127 pages
File Size : 42,6 Mb
Release : 2010
Category : Medical
ISBN : 9781615041176

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The Gastrointestinal Circulation by Peter R. Kvietys Pdf

The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography

Skeletal Muscle Circulation

Author : Ronald J. Korthuis
Publisher : Morgan & Claypool Publishers
Page : 147 pages
File Size : 47,8 Mb
Release : 2011
Category : Medical
ISBN : 9781615041831

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Skeletal Muscle Circulation by Ronald J. Korthuis Pdf

The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Regulation of Coronary Blood Flow

Author : Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 45,5 Mb
Release : 2013-11-09
Category : Medical
ISBN : 9784431683674

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Regulation of Coronary Blood Flow by Michitoshi Inoue,Masatsugu Hori,Shoichi Imai,Robert M. Berne Pdf

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

The Mechanics of the Circulation

Author : C. G. Caro
Publisher : Cambridge University Press
Page : 551 pages
File Size : 51,8 Mb
Release : 2012
Category : Mathematics
ISBN : 9780521151771

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The Mechanics of the Circulation by C. G. Caro Pdf

This classic book outlines the anatomy and physiology of the circulation and explains the mechanical principles that govern it.

The Oceanic Thermohaline Circulation

Author : Hendrik M. van Aken
Publisher : Springer Science & Business Media
Page : 337 pages
File Size : 53,8 Mb
Release : 2007-03-12
Category : Science
ISBN : 9780387480398

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The Oceanic Thermohaline Circulation by Hendrik M. van Aken Pdf

This book presents a global hydrographic description of the thermohaline circulation, an introduction to the theoretical aspects of this phenomenon, and observational evidence for the theory. The hydrographic description and the observational evidence are based on data sources available via internet, mainly from the World Oceanographic Experiment (WOCE). The book also offers an introduction to hydrographic analysis and interpretation.

Books in Motion in Early Modern Europe

Author : Daniel Bellingradt,Paul Nelles,Jeroen Salman
Publisher : Springer
Page : 305 pages
File Size : 40,7 Mb
Release : 2017-09-07
Category : Literary Criticism
ISBN : 9783319533667

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Books in Motion in Early Modern Europe by Daniel Bellingradt,Paul Nelles,Jeroen Salman Pdf

This book presents and explores a challenging new approach in book history. It offers a coherent volume of thirteen chapters in the field of early modern book history covering a wide range of topics and it is written by renowned scholars in the field. The rationale and content of this volume will revitalize the theoretical and methodological debate in book history. The book will be of interest to scholars and students in the field of early modern book history as well as in a range of other disciplines. It offers book historians an innovative methodological approach on the life cycle of books in and outside Europe. It is also highly relevant for social-economic and cultural historians because of the focus on the commercial, legal, spatial, material and social aspects of book culture. Scholars that are interested in the history of science, ideas and news will find several chapters dedicated to the production, circulation and consumption of knowledge and news media.

Vascular Biology of the Placenta

Author : Yuping Wang
Publisher : Biota Publishing
Page : 126 pages
File Size : 47,8 Mb
Release : 2017-06-23
Category : Medical
ISBN : 9781615047512

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Vascular Biology of the Placenta by Yuping Wang Pdf

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Hepatic Circulation

Author : W. Wayne Lautt
Publisher : Morgan & Claypool Publishers
Page : 174 pages
File Size : 49,5 Mb
Release : 2009-11-17
Category : Science
ISBN : 9781615040094

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Hepatic Circulation by W. Wayne Lautt Pdf

The Hepatic circulation is unique among vascular beds. The most obvious unique features include the dual vascular supply; the mechanism of intrinsic regulation of the hepatic artery (the hepatic arterial buffer response); the fact that portal blood flow, supplying two thirds of liver blood flow, is not controlled directly by the liver; the fact that 20% of the cardiac output rushes through the most vascularized organ in the body, driven by a pressure gradient of only a few millimeters of mercury; the extremely distensible capacitance and venous resistance sites; the unidirectional acinar blood flow that regulates parenchymal cell metabolic specialization; and the high concentration of macrophagic (Kupffer) cells filtering the blood. The liver is the only organ reported to have regional blood flow monitored by the autonomic nervous system. This mechanism, when dysfunctional, accounts for the hepatorenal syndrome and offers a mechanistic therapeutic target to treat this syndrome. The trigger for liver regeneration is dependent on hepatic hemodynamics so that chronic liver blood flow regulates liver cell mass. In severe liver disease, the whole body circulation is reorganized, by forming portacaval shunts, to accommodate the increased intrahepatic venous resistance. These shunts protect the venous drainage of the splanchnic organs but lead to loss of major regulatory roles of the liver. The development of knowledge of the hepatic vasculature is presented from a historical perspective with modern concepts summarized based on the perspective of the author's four decades of devotion to this most marvelous of organs. Table of Contents: Acknowledgements / Historical Perspectives / Overview / Fluid Exchange / Capacitance / Resistance in the Hepatic Artery / Resistance in the Venous System / Fetal and Neonatal Hepatic Circulation / In Vivo Pharmacodynamic Approaches / Nitric Oxide / Adenosine / Hepatic Nerves / Hepatic Circulation and Toxicology / Hepatorenal Syndrome / Integrative Hepatic Response to Hemorrhage / Blood Flow Regulation of Hepatocyte Proliferation / Multiple Mechanisms Maintaining a Constant Hepatic Blood Flow to Liver Mass Ratio / Pathopharmacology and Repurposing Drugs as a Research Strategy / References

The Ocean Circulation Inverse Problem

Author : Carl Wunsch
Publisher : Cambridge University Press
Page : 466 pages
File Size : 42,9 Mb
Release : 1996-06-13
Category : Mathematics
ISBN : 0521480906

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The Ocean Circulation Inverse Problem by Carl Wunsch Pdf

This book addresses the problem of inferring the state of the ocean circulation, from a mathematical perspective.

Atmospheric Circulation Dynamics and General Circulation Models

Author : Masaki Satoh
Publisher : Springer Science & Business Media
Page : 730 pages
File Size : 43,5 Mb
Release : 2013-07-04
Category : Science
ISBN : 9783642135743

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Atmospheric Circulation Dynamics and General Circulation Models by Masaki Satoh Pdf

General circulation models (GCMs), which define the fundamental dynamics of atmospheric circulation, are nowadays used in various fields of atmospheric science such as weather forecasting, climate predictions and environmental estimations. The Second Edition of this renowned work has been updated to include recent progress of high resolution global modeling. It also contains for the first time aspects of high-resolution global non-hydrostatic models that the author has been studying since the publication of the first edition. Some highlighted results from the Non-hydrostatic ICosahedral Atmospheric Model (NICAM) are also included. The author outlines the theoretical concepts, simple models and numerical methods for modeling the general circulation of the atmosphere. Concentrating on the physical mechanisms responsible for the development of large-scale circulation of the atmosphere, the book offers comprehensive coverage of an important and rapidly developing technique used in the atmospheric science. Dynamic interpretations of the atmospheric structure and their aspects in the general circulation model are described step by step.