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Author : Harry Stack Sullivan Publisher : W. W. Norton & Company Page : 408 pages File Size : 40,8 Mb Release : 1973 Category : Medical ISBN : 0393006883
Clinical Studies in Psychiatry by Harry Stack Sullivan Pdf
This volume sets forth the central ideas of Dr. Sullivan's theory of personality. His view of psychiatry as the study of interpersonal relations has opened an entirely new approach to the treatment of mental disorders and the study of human personality.
Author : Brian S. Everitt,Simon Wessely Publisher : John Wiley & Sons Page : 248 pages File Size : 52,6 Mb Release : 2008-04-15 Category : Medical ISBN : 047072384X
Clinical Trials in Psychiatry by Brian S. Everitt,Simon Wessely Pdf
At last – a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those seeking solutions to numerous problems relating to design, methodology and analysis of such trials. Practical examples and applications are used to ground theory whenever possible. The Second Edition includes new information regarding: Recent important psychiatric trials More specific discussion of psychiatry in the USA and the particular problems of trials in the USA, including comments about the FDA (U.S. Food and Drug Administration) An extended chapter on meta-analysis Further discussion of sub-group analysis Special features include appendices outlining how to design and report clinical trials, what websites and software programs are appropriate and an extensive reference section. From the reviews of the First Edition: “Everitt & Wessely are to be congratulated on producing an excellent guide to help overcome the snags in clinical trial research. Clearly written and in an engrossing style, the book is likely to become a classic textbook on clinical trials, and not just in psychiatry. The authors’ enthusiasm and grasp of clinical trial research make for a gripping and insightful read...it is one of the very best books that has been written on clinical trials.” THE BRITISH JOURNAL OF PSYCHIATRY "The experience of both authors in this area gives the book a very pragmatic approach grounded in reality, with theoretical overviews invariably being followed by practical examples and applications... an invaluable companion to anyone involved in, or contemplating undertaking, clinical trials research.” PSYCHOLOGICAL MEDICINE
Elizabeth Ryznar,Aderonke B. Pederson,Mark A. Reinecke,John G. Csernansky
Author : Elizabeth Ryznar,Aderonke B. Pederson,Mark A. Reinecke,John G. Csernansky Publisher : Oxford University Press Page : 449 pages File Size : 50,9 Mb Release : 2020-01-22 Category : Medical ISBN : 9780192538871
Landmark Papers in Psychiatry by Elizabeth Ryznar,Aderonke B. Pederson,Mark A. Reinecke,John G. Csernansky Pdf
Advances in the practice of psychiatry have occurred in "fits and starts" over the last several decades. These advances are evident to anyone long affiliated with the field and are best appreciated through direct experience of living through the times. These advances can also be gleaned from historical overviews in textbooks or the recollections of one's teachers and mentors. Returning to the original papers that have ushered in these changes is rarely done for various, mostly practical, reasons. Filtering through thousands of articles in psychiatry may prove daunting, access to the manuscripts may be limited (especially for papers not available electronically), and understanding their impact requires a broader context. Moreover, with so much active research currently occurring in various branches of psychiatry, current practitioners or trainees may find their attention focused on the present, and this is reinforced by electronic search algorithms, which return articles in reverse chronological order. Not surprisingly, citations for articles in virtually all fields decline precipitously for articles over five years old. As scholars and professionals, we are losing touch with our academic heritage. Yet navigating the future of psychiatry requires a firm understanding of its past. This resource serves as a guide for anyone seeking to understand the evolution of psychiatry as a scientific discipline. It does so by summarizing over 100 landmark papers in psychiatry and placing their scientific contributions within a historical context. An introductory section sets the stage for the major theoretical constructs within the field, with chapters devoted to ontology and nosology. Subsequent sections examine major facets of the theory and practice of psychiatry, such as pathogenesis of psychiatric illness, pharmacotherapy, psychotherapy, and somatic treatments. These sections are divided logically into chapters addressing important contributions to the understanding and treatment of specific disorders. A final section explores ethical considerations within each field. This framework echoes the complexity of psychiatry, which cannot be reduced to a single set of diagnoses or subspecialty categories. Highlighting the research trajectory of psychiatry, this resource will appeal to academics, trainees, and practitioners who desire a comprehensive, easy-to-read, up-to-date collection of psychiatry's pivotal moments. By understanding the challenges, inspirations, and insights from the past, readers will be better poised to address new and ongoing challenges within the field.
Author : Patrick D. McGorry,Ian B. Hickie Publisher : Cambridge University Press Page : 301 pages File Size : 49,5 Mb Release : 2019-08-29 Category : Medical ISBN : 9781108718844
Global Mental Health Trials by Graham Thornicroft,Vikram Patel Pdf
Global mental health is a dynamic field of global health; a core aspect of the story which has led to its emergence has been the conduct of randomised controlled trials (RCTs) evaluating innovative delivery systems of packages of care for mental disorders in low-resource settings. Global Mental Health Trials brings together many of the world's leading researchers active in the fields of RCTs in low- and medium-resource countries and settings related to improving mental health care. It presents clear and practical information about how to conduct such trials in these settings, along with critical methodological and ethical issues related to such trials, learning from the positive and negative experiences of expert scientists in many countries worldwide who have completed such trials. This book serves as a valuable resource for practitioners in mental health - psychiatrists, psychiatric nurses nursing, psychologists, social workers, and occupational therapists - as well as researchers in the areas of psycho-social treatments in mental health, mental health services research, and programme and systems evaluation.
Clinical Trials in Psychiatry by Brian Everitt,Simon Wessely Pdf
'Clinical Trials in Psychiatry' explains RCTs for mental health professionals. It starts by discussing why we need trials and why they are the best way of deciding if a treatment works. It then describes the different types of trial, how to analyze the results, and how to conduct a trial.
Research Methods in Psychiatry by Chris Freeman,Peter J. Tyrer,Peter Tyrer Pdf
This updated comprehensive guide to psychiatric research methods takes the reader from getting started in research through to publishing a paper, with advice on avoiding common pitfalls along the way. Systematic analysis and meta-analysis, epidemiology, qualitative research, and research focused on a few patients are discussed, together with the principles of validity and reliability in the assessment of psychological variables and statistical aspects of the design and analysis of clinical trials. Five completely new chapters cover topics such as research from the trainee's perspective and research in learning disability and child and adolescent psychiatry. A key text for psychiatric trainees embarking on research projects, this book will also be useful to psychiatrists supervising research projects, and those in the social sciences with an interest in carrying out research or critically reviewing the published evidence. Topics covered include setting up a research project, how to make a comprehensive review of the literature, choosing a rating scale, and getting research published.
Clinical Trials in Psychopharmacology by Marc Hertzman,Lawrence Adler Pdf
Although clinical trials were virtually unheard of in psychiatry for many years, they are now the gold standard for judging whether drugs are safe and useful. But should they be? What is the true status of clinical trials? Even when they ostensibly demonstrate a benefit of a certain treatment, the strict patient selection criteria, poor compliance and high drop-out rate leave the conclusions open to question. Are the new treatments really better or more cost-effective than the old? Do they have fewer side effects? In this book the authors take a critical look at recent developments and present a series of trenchant and challenging observations. Section I examines the significant changes in law and the regulatory environment that have occurred during the past ten years. Has fossilization handicapped the US Food and Drug Administration in promoting treatment advances? How can the plethora of findings be regulated? This is particularly pertinent in genomic studies and there are two chapters addressing the impact of genomics on psychiatric research. This section also addresses the role of women in drug trials – a group long excluded but now demanding a part, for without testing how can optimal treatments be devised? The next two Sections highlight clinical trials in the major areas of psychiatric pharmacological treatment, including Mood Disorders, especially Bipolar, Anxiety Disorders, and addictions. Chapters on pharmacological treatments for Eating Disorders, Attention Deficit Disorder, Autism and Asperger’s Syndrome, and Impulse Control Disorder represent the latest thinking on these subjects. The final Section contains a consummate example of out-of-the [Western]- box thinking, namely consideration of herbal medicines – used by a large number of patients, with or without medical supervision. We conclude with a close look at the problem of side effects, then selected thoughts about methodology. Clearly written, the text provides immediate access to new developments across the spectrum of drug testing. Clinical Trials in Psychopharmacology: A Better Brain is provocative reading for psychiatrists, pharmacologists and all those interested in improved drug treatments for patients with mental illness. Raises questions about the conduct of trials and the credibility of their outcomes that are relevant not just in psychiatry but all areas of medicine Discusses the ethical problems in assessing outcomes in humans, including children
Developments in Psychiatry in India by Savita Malhotra,Subho Chakrabarti Pdf
The volume evaluates major developments in psychiatry in India from the 1950s, and highlights the areas where Indian psychiatry has contributed to the development of the subject worldwide. The chapters review international as well as Indian developments in psychiatry and its sub-specialities. A wide range of clinical, research and policy-related topics have been covered in the volume, which begins with an overview of the history of psychiatry in India, moving on to developments in various sub-specialities of psychiatry in the last 60 years or so. It then specifically discusses developments in psychology and psychodynamics, general adult and child psychiatry, substance use psychiatry, community psychiatry, liaison psychiatry, and other psychiatric sub-specialities. Developments in treatment, the status of training and service in psychiatry and legal issues related to the practice of psychiatry in India are also included. The contributors to this volume are nationally and internationally recognized experts in different areas of psychiatry. Most of them have had some association, or are currently associated, with the Department of Psychiatry at the Post Graduate Institute of Medical Education and Research, Chandigarh, India.
James E. Mitchell,Ross D. Crosby,Stephen A. Wonderlich,David E. Adson
Author : James E. Mitchell,Ross D. Crosby,Stephen A. Wonderlich,David E. Adson Publisher : American Psychiatric Pub Page : 219 pages File Size : 43,9 Mb Release : 2008-11-01 Category : Medical ISBN : 9781585628261
Elements of Clinical Research in Psychiatry by James E. Mitchell,Ross D. Crosby,Stephen A. Wonderlich,David E. Adson Pdf
Clinical research is often thought of as a dry and somewhat arcane pursuit. Not so, assert the editors of Elements of Clinical Research in Psychiatry. The editors, all actively engaged in clinical research, bring this topic to life by combining a boundless enthusiasm for their chosen field with a depth of knowledge rarely seen in the literature. They show that clinical research can be rewarding not only because the research results contribute to improving the welfare of psychiatric patients, but also because the research process itself is exciting. Arguably the definitive guidebook on clinical psychiatric research, this volume discusses Careers in clinical mental health research -- Describes what clinical psychiatric researchers do and how to get started on this career path. Research design, measurement, and assessment -- Covers all aspects of research design, defines and evaluates measurement types, and details various assessment methods (from interviews and questionnaires to lab tests and brain images). Descriptive and inferential statistics -- Shows how statistics are used to analyze and summarize measurement data. Research support -- Provides a roadmap for those seeking research support in the U.S. (more than 90% is funded via NIH), detailing how to write grants from the ground up. Use of human subjects (the Institutional Review Board [IRB]) and ethics and misconduct -- Demystifies the often intimidating process of seeking and receiving IRB approval, with tips on how to work with the IRB and complete its consent forms; uses a series of practical scenarios, including a highly publicized case of alleged misconduct, to illustrate complex ethics and misconduct issues. Writing journal articles, reviewing manuscripts, and giving scientific presentations -- Presents the nuts and bolts of publishing journal articles; gives step-by-step advice for reviewing manuscripts and giving oral presentations, symposia, poster sessions, and colloquia. Carefully chosen appendixes provide readers with additional information they can use right away, augmented by an index and detailed reference list for further investigation. Anyone considering clinical psychiatric research as a career option will find in this succinct and eminently practical volume the single source they need. Practicing psychiatrists interested in specific areas of clinical research, such as human subject use or biomedical ethics, will also find much of interest here. Replete with useful information, these stimulating discussions provide the building blocks for embarking upon -- and enhancing -- a successful career in clinical psychiatric research.
Research Designs and Methods in Psychiatry by Maurizio Fava,Jerrold F. Rosenbaum Pdf
This important contribution to psychiatric literature, coming from a group of investigators who have developed a successful clinical research unit over the last decade, has the immediacy, clarity, and practicality expected from those who have personally wrestled with the difficult issues of design and data analysis. In addition, it draws upon a number of pioneers who have devised methods now used broadly in treatment research in psychiatry. This amalgam presents a very informative, down to earth and readable methods book, that should become the standard text in this growing field of investigation. The volume is divided into four sections: general issues, epidemiology, clinical studies, and psychopharmacology. The material offered in the book serves both as a review for clinical researchers and as a guide to clinicians to facilitate exploration in the fields of psychopathology and treatment. The path from clinical empiricism to scientific process ultimately leads to increased professional gratification and enhanced patient care.
Clinical Trials of Antidepressants by Martin M. Katz Pdf
This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new molecules, and reducing waste. Case studies and a review of salient depression scales illustrate the potential benefits of such wide-scale change. Included in the coverage: Why now the need for a new clinical trials model for antidepressants? Aims and basic requirements of clinical trials: conventional and component-specific models. Methods for measuring the components and the profile of drug actions: the multivantaged approach. Achieving the ideal clinical trial: an example of the merged componential and established models. Prediction and shortening the clinical trial. The video clinical trial. Clinical Trials of Antidepressants will interest a varied audience, including clinical investigators, academic and pharmaceutical company scientists, clinical trial organizations, psychiatrists, outpatient physicians, psychotherapists, clinical psychologists, psychology graduate students, medical students, and government agencies such as the FDA.
