Clostridium Difficile

Author : Henning Sommermeyer,Jacek Piątek
Publisher : Springer Nature
Page : 96 pages
File Size : 54,7 Mb
Release : 2021-09-27
Category : Medical
ISBN : 9783030811006

Get Book

Clostridioides difficile by Henning Sommermeyer,Jacek Piątek Pdf

The book provides a comprehensive overview of the current knowledge about Clostridioides (C.) difficile (formerly known as Clostridium difficile) and Clostridioides difficile infections (CDI). The diseases caused by C. difficile range from mild diarrhea to fulminant and in some cases fatal colitis. Historically, CDI was considered mainly as a hospital-acquired problem. Today, a significant portion of CDI is community acquired. Triggered by the introduction of new antibiotics, hypervirulent and multi-drug resistant strains of C. difficile (e.g., C. difficile ribotype R027) have emerged and spread across the globe. The volume covers the microbiology, pathophysiology, epidemiology, risk factors for CDI, diagnosis, clinical pictures, treatment and prophylaxis. It includes an extensive reference list that allows an easy navigation through the original research publications. Clostridioides difficile helps the reader gain a better understanding of C. difficile, the challenges that may arise and the available treatment options. Given its broad coverage and features, it will appeal to a wide readership, from gastroenterologists through general physicians, nurses, and other healthcare providers, to students.

Author : Teena Chopra
Publisher : Springer Nature
Page : 80 pages
File Size : 53,9 Mb
Release : 2019-11-14
Category : Medical
ISBN : 9783030297725

Get Book

Clostridium Difficile Infection in Long-Term Care Facilities by Teena Chopra Pdf

This book aims to fill knowledge gap among healthcare workers about Clostridium difficile (also known as C.difficile and CDI) among aging patients, especially those in long-term care facilities (LTCFs). Written by experts in infectious diseases and geriatric medicine, this book provides comprehensive information on all aspects of CDI pertaining to LTCF settings, including epidemiology, diagnosis, prevention, management and the unique challenges faced by LTCFs with regards to the CDI problem. The book begins by introducing the topic as it relates to aging patients before delving into the various aspects of CDI management. Topics include infection control and prevention, treatment of CDI, and the establishment of antibiotic stewardship programs to reduce inappropriate antibiotic use and reduce CDI rates. The book also features a chapter on probiotics for the prevention of CDI and new strategies to monitor environmental cleaning practices of CDI patient rooms that do not appear in any other resource. Clostridium Difficile Infection in Long-Term Care Facilities is an excellent resource for geriatricians, infectious diseases specialists, long-term care administrators, nurses, pharmacists, researchers, and all clinicians working with infections in long-term care settings.

Author : American Academy of Pediatrics
Publisher : Unknown
Page : 440 pages
File Size : 46,7 Mb
Release : 2007
Category : Health & Fitness
ISBN : 158110247X

Get Book

Red Book Atlas of Pediatric Infectious Diseases by American Academy of Pediatrics Pdf

Based on key content from Red Book: 2006 Report of the Committee on Infectious Diseases, 27th Edition, the new Red Bookr Atlas is a useful quick reference tool for the clinical diagnosis and treatment of more than 75 of the most commonly seen pediatric infectious diseases. Includes more than 500 full-color images adjacent to concise diagnostic and treatment guidelines. Essential information on each condition is presented in the precise sequence needed in the clinical setting: Clinical manifestations, Etiology, Epidemiology, Incubation period, Diagnostic tests, Treatment

Author : Shymaa Enany
Publisher : BoD – Books on Demand
Page : 162 pages
File Size : 47,9 Mb
Release : 2017-09-27
Category : Science
ISBN : 9789535134275

Get Book

Clostridium Difficile by Shymaa Enany Pdf

Clostridium difficile bacteria could be found everywhere around us: in the air, water, and soil and in the feces of humans and animals. You can easily become infected with C. difficile if you touch contaminated clothing, sheets, or other objects and then touch your mouth. Many people have the bacteria in their intestines and never have any symptoms. Still, it can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. The chance of developing a C. difficile infection increases with the usage of high doses of antibiotics over a prolonged period; thus, it is most often spread in the healthcare facilities between workers, patients, and residents. Each year in the United States, almost a half million people get sick from C. difficile, and approximately 29,000 patients died within 30 days of its initial diagnosis. Nowadays, C. difficile infections have become more frequent, severe, and difficult to treat. Therefore, the early diagnosis and the suitable treatment have become a real demand. In this book, we present the experience of worldwide specialists on the diagnosis and the treatment of C. difficile infections along with its lights and shadows.

Author : Christopher O'Neal,Raf Rizk
Publisher : Lulu.com
Page : 152 pages
File Size : 55,5 Mb
Release : 2011-08-01
Category : Health & Fitness
ISBN : 9780578089133

Get Book

Clostridium Difficile by Christopher O'Neal,Raf Rizk Pdf

Clostridium difficile, a potentially deadly hospital-acquired infection, strikes millions annually around the world. Both the incidence and severity of the disease are growing. A sizable proportion of patients who acquire a C. difficile infection will suffer from repeated recurrences of the disease. This book is meant to educate patients, their families, and their doctors about this growing infectious threat.

Author : Mark H. Wilcox
Publisher : Elsevier Health Sciences
Page : 201 pages
File Size : 44,9 Mb
Release : 2015-04-07
Category : Medical
ISBN : 9780323356800

Get Book

Clostridium difficile Infection, An Issue of Infectious Disease Clinics of North America, by Mark H. Wilcox Pdf

This issue of Infectious Disease Clinics of North America, guest edited by Dr. Mark H. Wilcox, is devoted to Clostridium Difficile Infection. Articles in this issue include: Potential sources of C. difficile for human infection; Colonisation versus carriage of C. difficile; Diagnostic pitfalls in C. difficile infection; The epidemiology of C. difficile infection in and outside of healthcare institutions; What makes epidemic C. difficile strains epidemic?: Fact versus fiction; Environmental interventions to control C. difficile infection; The contribution of strains and hosts to outcomes in C. difficile infection; Treatment of C. difficile infection; Faecal microbiota transplantation for the management of C. difficile infection; The morbidity, mortality, and costs associated with C. difficile infection; The potential of probiotics to prevent C. difficile infection; The prospect for vaccines to prevent C. difficile infection; and Predictive value of models of C. difficile infection.

Author : Paola Mastrantonio,Maja Rupnik
Publisher : Springer
Page : 261 pages
File Size : 52,5 Mb
Release : 2018-01-29
Category : Medical
ISBN : 9783319727998

Get Book

Updates on Clostridium difficile in Europe by Paola Mastrantonio,Maja Rupnik Pdf

This book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are discussed for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.

Author : Julia S. Garner
Publisher : Unknown
Page : 80 pages
File Size : 47,9 Mb
Release : 1983
Category : Cross infection
ISBN : UOM:39015029218875

Get Book

Guideline for Isolation Precautions in Hospitals by Julia S. Garner Pdf

Author : Candice Shelton
Publisher : Unknown
Page : 143 pages
File Size : 46,7 Mb
Release : 2016
Category : HEALTH & FITNESS
ISBN : 1634844270

Get Book

Superbugs by Candice Shelton Pdf

The first section of this book discusses Clostridium difficile Infections (CDI). There is no consensus on the definition of severe CDI, since it varies depending on the authors or clinical practice guidelines consulted. Severe CDI can be defined as an episode of CDI with one or more specific signs and symptoms of severe colitis or a complicated clinical course, with significant systemic toxicity and shock, requiring ICU admission or a colectomy, or resulting in death. The chapters in this section examine the risk factors for the development of severe CDI; study the advances in fecal microbiota transplantation; and provide management strategies of CDI in intensive care units. Section Two of this book provides research on Klebsiella pneumoniae infections. Klebsiella pneumoniae producing KPC-type carbapenemase (KPC-Kp) is an emerging problem epidemiologically, diagnostically, and therapeutically. Carbapenem-resistant Klebsiella pneumoniae have emerged as a class of pathogens that pose a significant threat to patients admitted to healthcare facilities. The first chapter of this section reviews the molecular epidemiology of Klebsiella pneumoniae carbapenemase. The following chapters discuss KPC-Kp; Klebsiella pneumoniae brain abscess in adults; and the causes of Ankylosing spondylitis and Crohn's disease.

Author : Paola Mastrantonio,Maja Rupnik
Publisher : Springer Nature
Page : 368 pages
File Size : 49,9 Mb
Release : 2024-01-04
Category : Medical
ISBN : 9783031421082

Get Book

Updates on Clostridioides difficile in Europe by Paola Mastrantonio,Maja Rupnik Pdf

This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.

Author : K. Aktories,T.D. Wilkins
Publisher : Springer Science & Business Media
Page : 150 pages
File Size : 47,5 Mb
Release : 2013-04-17
Category : Science
ISBN : 9783662062722

Get Book

Clostridium difficile by K. Aktories,T.D. Wilkins Pdf

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.

Author : Somnath Mookherjee,Lauren A. Beste,Jared W. Klein,Jennifer Wright
Publisher : Springer Nature
Page : 347 pages
File Size : 42,5 Mb
Release : 2020-09-30
Category : Education
ISBN : 9783030348144

Get Book

Chalk Talks in Internal Medicine by Somnath Mookherjee,Lauren A. Beste,Jared W. Klein,Jennifer Wright Pdf

This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.

Author : J. Thomas Lamont
Publisher : In 30 Minutes Guides
Page : 0 pages
File Size : 45,9 Mb
Release : 2022-06
Category : Clostridium difficile
ISBN : 1641880783

Get Book

C. Diff In 30 Minutes by J. Thomas Lamont Pdf

Revised and updated second edition! If you or a loved one has C. diff, C. Diff In 30 Minutes can be an invaluable and expert resource to understand and deal with the infection and symptoms. Author, doctor, and Harvard Medical School Professor J. Thomas Lamont, M.D. uses plain-English explanations and case studies to explain how C. diff can be successfully managed.

Author : David E. Beck,John L. Rombeau,Michael J. Stamos,Steven D. Wexner
Publisher : Springer Science & Business Media
Page : 1042 pages
File Size : 47,7 Mb
Release : 2009-06-12
Category : Medical
ISBN : 9780387734408

Get Book

The ASCRS Manual of Colon and Rectal Surgery by David E. Beck,John L. Rombeau,Michael J. Stamos,Steven D. Wexner Pdf

The ASCRS Textbook of Surgery of the Colon and Rectum offers a comprehensive textbook designed to provide state of the art information to residents in training and fully trained surgeons seeking recertification. The textbook also supports the mission of the ASCRS to be the world’s authority on colon and rectal disease. The combination of junior and senior authors selected from the membership of the ASCRS for each chapter will provide a comprehensive summary of each topic and allow the touch of experience to focus and temper the material. This approach should provide the reader with a very open minded, evidence based approach to all aspects of colorectal disease. Derived from the textbook, The ASCRS Manual of Surgery of the Colon and Rectum offers a “hands on” version of the textbook, written with the same comprehensive, evidence-based approach but distilled to the clinical essentials. In a handy pocket format, readers will find the bread and butter information for the broad spectrum of practice. In a consistent style, each chapter outlines the condition or procedure being discussed in a concise outline format – easy to read, appropriately illustrated and referenced.

Author : Jean-Claude Rambaud,J.Thomas LaMont
Publisher : Springer Science & Business Media
Page : 143 pages
File Size : 54,8 Mb
Release : 2013-12-01
Category : Medical
ISBN : 9782817809243

Get Book

Ökosystem Darm Special by Jean-Claude Rambaud,J.Thomas LaMont Pdf

Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much earlier. A brief historical review of the discovery of the enteropathogenicity of C. difficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. Until 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus au reus [ 11], a concept strengthened by the spectacular therapeutic action of vancomycin.