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Common Mistakes in Meta-Analysis by Michael Borenstein Pdf
Among the thousands of meta-analyses that have been published over the past several decades, there are a number of mistakes that appear on a fairly regular basis. This book outlines the most common mistakes, using examples in medicine, epidemiology, education, psychology, criminal justice, and other fields. For each, it explains why it is a mistake, the implications of the mistake, and how to correct the mistake. The book is intended primarily for researchers, and so the discussion is conceptual rather than statistical. The examples show the real-world consequences of the mistakes, explaining (for example) how the mistakes can lead to the adoption of interventions that may actually be harmful in some populations. The book includes a section with examples that show how to report the results of an analysis correctly. These examples can serve as templates for reporting an analysis, while avoiding the mistakes discussed in earlier chapters. The book's author is the co-author of the text Introduction to Meta-Analysis, the best-selling text in this field. In the current volume he draws on his experience teaching meta-analysis to thousands of researchers as well as his experience as a reviewer of meta-analyses for numerous journals.
Larry V. Hedges,Julian P. T. Higgins,Hannah R. Rothstein,Michael Borenstein
Author : Larry V. Hedges,Julian P. T. Higgins,Hannah R. Rothstein,Michael Borenstein Publisher : John Wiley & Sons Page : 434 pages File Size : 40,8 Mb Release : 2011-08-24 Category : Medical ISBN : 9781119964377
Introduction to Meta-Analysis by Larry V. Hedges,Julian P. T. Higgins,Hannah R. Rothstein,Michael Borenstein Pdf
This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research process Shows how to compute effects sizes and treatment effects Explains the fixed-effect and random-effects models for synthesizing data Demonstrates how to assess and interpret variation in effect size across studies Clarifies concepts using text and figures, followed by formulas and examples Explains how to avoid common mistakes in meta-analysis Discusses controversies in meta-analysis Features a web site with additional material and exercises A superb combination of lucid prose and informative graphics, written by four of the world’s leading experts on all aspects of meta-analysis. Borenstein, Hedges, Higgins, and Rothstein provide a refreshing departure from cookbook approaches with their clear explanations of the what and why of meta-analysis. The book is ideal as a course textbook or for self-study. My students, who used pre-publication versions of some of the chapters, raved about the clarity of the explanations and examples. David Rindskopf, Distinguished Professor of Educational Psychology, City University of New York, Graduate School and University Center, & Editor of the Journal of Educational and Behavioral Statistics. The approach taken by Introduction to Meta-analysis is intended to be primarily conceptual, and it is amazingly successful at achieving that goal. The reader can comfortably skip the formulas and still understand their application and underlying motivation. For the more statistically sophisticated reader, the relevant formulas and worked examples provide a superb practical guide to performing a meta-analysis. The book provides an eclectic mix of examples from education, social science, biomedical studies, and even ecology. For anyone considering leading a course in meta-analysis, or pursuing self-directed study, Introduction to Meta-analysis would be a clear first choice. Jesse A. Berlin, ScD Introduction to Meta-Analysis is an excellent resource for novices and experts alike. The book provides a clear and comprehensive presentation of all basic and most advanced approaches to meta-analysis. This book will be referenced for decades. Michael A. McDaniel, Professor of Human Resources and Organizational Behavior, Virginia Commonwealth University
Doing Meta-Analysis with R by Mathias Harrer,Pim Cuijpers,Toshi A. Furukawa,David D. Ebert Pdf
Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered, including calculation and pooling of outcome measures, forest plots, heterogeneity diagnostics, subgroup analyses, meta-regression, methods to control for publication bias, risk of bias assessments and plotting tools. Advanced but highly relevant topics such as network meta-analysis, multi-three-level meta-analyses, Bayesian meta-analysis approaches and SEM meta-analysis are also covered. A companion R package, dmetar, is introduced at the beginning of the guide. It contains data sets and several helper functions for the meta and metafor package used in the guide. The programming and statistical background covered in the book are kept at a non-expert level, making the book widely accessible. Features • Contains two introductory chapters on how to set up an R environment and do basic imports/manipulations of meta-analysis data, including exercises • Describes statistical concepts clearly and concisely before applying them in R • Includes step-by-step guidance through the coding required to perform meta-analyses, and a companion R package for the book
Meta-Analysis with R by Guido Schwarzer,James R. Carpenter,Gerta Rücker Pdf
This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: publication bias and small study effects; missing data; multivariate meta-analysis, network meta-analysis; and meta-analysis of diagnostic studies.
Statistical Methods for Meta-Analysis by Larry V. Hedges,Ingram Olkin Pdf
The main purpose of this book is to address the statistical issues for integrating independent studies. There exist a number of papers and books that discuss the mechanics of collecting, coding, and preparing data for a meta-analysis , and we do not deal with these. Because this book concerns methodology, the content necessarily is statistical, and at times mathematical. In order to make the material accessible to a wider audience, we have not provided proofs in the text. Where proofs are given, they are placed as commentary at the end of a chapter. These can be omitted at the discretion of the reader. Throughout the book we describe computational procedures whenever required. Many computations can be completed on a hand calculator, whereas some require the use of a standard statistical package such as SAS, SPSS, or BMD. Readers with experience using a statistical package or who conduct analyses such as multiple regression or analysis of variance should be able to carry out the analyses described with the aid of a statistical package.
Common Errors in Statistics (and How to Avoid Them) by Phillip I. Good,James W. Hardin Pdf
Praise for the First Edition of Common Errors in Statistics " . . . let me recommend Common Errors to all those who interactwith statistics, whatever their level of statistical understanding. . . " --Stats 40 " . . . written . . . for the people who define good practicerather than seek to emulate it." --Journal of Biopharmaceutical Statistics " . . . highly informative, enjoyable to read, and of potential useto a broad audience. It is a book that should be on the referenceshelf of many statisticians and researchers." --The American Statistician " . . . I found this book the most easily readable statistics bookever. The credit for this certainly goes to Phillip Good." --E-STREAMS A tried-and-true guide to the proper application ofstatistics Now in a second edition, the highly readable Common Errors inStatistics (and How to Avoid Them) lays a mathematically rigorousand readily accessible foundation for understanding statisticalprocedures, problems, and solutions. This handy field guideanalyzes common mistakes, debunks popular myths, and helps readersto choose the best and most effective statistical technique foreach of their tasks. Written for both the newly minted academic and the professional whouses statistics in their work, the book covers creating a researchplan, formulating a hypothesis, specifying sample size, checkingassumptions, interpreting p-values and confidence intervals,building a model, data mining, Bayes' Theorem, the bootstrap, andmany other topics. The Second Edition has been extensively revisedto include: * Additional charts and graphs * Two new chapters, Interpreting Reports and Which RegressionMethod? * New sections on practical versus statistical significance andnonuniqueness in multivariate regression * Added material from the authors' online courses atstatistics.com * New material on unbalanced designs, report interpretation, andalternative modeling methods With a final emphasis on both finding solutions and the great valueof statistics when applied in the proper context, this book iseminently useful to students and professionals in the fields ofresearch, industry, medicine, and government.
Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research
Author : Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Publisher : National Academies Press Page : 267 pages File Size : 42,9 Mb Release : 2011-07-20 Category : Medical ISBN : 9780309164252
Finding What Works in Health Care by Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Pdf
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
Scientific progress depends on good research, and good research needs good statistics. But statistical analysis is tricky to get right, even for the best and brightest of us. You'd be surprised how many scientists are doing it wrong. Statistics Done Wrong is a pithy, essential guide to statistical blunders in modern science that will show you how to keep your research blunder-free. You'll examine embarrassing errors and omissions in recent research, learn about the misconceptions and scientific politics that allow these mistakes to happen, and begin your quest to reform the way you and your peers do statistics. You'll find advice on: –Asking the right question, designing the right experiment, choosing the right statistical analysis, and sticking to the plan –How to think about p values, significance, insignificance, confidence intervals, and regression –Choosing the right sample size and avoiding false positives –Reporting your analysis and publishing your data and source code –Procedures to follow, precautions to take, and analytical software that can help Scientists: Read this concise, powerful guide to help you produce statistically sound research. Statisticians: Give this book to everyone you know. The first step toward statistics done right is Statistics Done Wrong.
The Handbook of Research Synthesis and Meta-Analysis by Harris Cooper,Larry V. Hedges,Jeffrey C. Valentine Pdf
Research synthesis is the practice of systematically distilling and integrating data from many studies in order to draw more reliable conclusions about a given research issue. When the first edition of The Handbook of Research Synthesis and Meta-Analysis was published in 1994, it quickly became the definitive reference for conducting meta-analyses in both the social and behavioral sciences. In the third edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of classic chapters and add new sections that evaluate cutting-edge developments in the field. The Handbook of Research Synthesis and Meta-Analysis draws upon groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. The editors and leading scholars guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook incorporates state-of-the-art techniques from all quantitative synthesis traditions and distills a vast literature to explain the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, the development of machine-based abstract screening, the increased use of meta-regression and the problems of missing data. The Handbook also addresses the non-statistical aspects of research synthesis, including searching the literature and developing schemes for gathering information from study reports. Those engaged in research synthesis will find useful advice on how tables, graphs, and narration can foster communication of the results of research syntheses. The third edition of the Handbook provides comprehensive instruction in the skills necessary to conduct research syntheses and represents the premier text on research synthesis. Praise for the first edition: "The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding." —Chance "Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual."—British Medical Journal When the first edition of The Handbook of Research Synthesis was published in 1994, it quickly became the definitive reference for researchers conducting meta-analyses of existing research in both the social and biological sciences. In this fully revised second edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of the Handbook's classic chapters, as well as entirely new sections reporting on the most recent, cutting-edge developments in the field. Research synthesis is the practice of systematically distilling and integrating data from a variety of sources in order to draw more reliable conclusions about a given question or topic. The Handbook of Research Synthesis and Meta-Analysis draws upon years of groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. Cooper, Hedges, and Valentine have assembled leading authorities in the field to guide the reader through every stage of the research synthesis process—problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis and Meta-Analysis incorporates state-of-the-art techniques from all quantitative synthesis traditions. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed by the authors are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, and the problem of missing data. The Handbook of Research Synthesis and Meta-Analysis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, and developing schemes for gathering information from study reports. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be used to provide the most meaningful communication of the results of research synthesis. In addition, the editors address the potentials and limitations of research synthesis, and its future directions. The past decade has been a period of enormous growth in the field of research synthesis. The second edition Handbook thoroughly revises original chapters to assure that the volume remains the most authoritative source of information for researchers undertaking meta-analysis today. In response to the increasing use of research synthesis in the formation of public policy, the second edition includes a new chapter on both the strengths and limitations of research synthesis in policy debates
Systematic Reviews in Health Care by Matthias Egger,George Davey-Smith,Douglas Altman Pdf
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
Cochrane Handbook for Systematic Reviews of Interventions by Julian P. T. Higgins,Sally Green Pdf
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care
Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care Publisher : National Academies Press Page : 473 pages File Size : 40,9 Mb Release : 2015-12-29 Category : Medical ISBN : 9780309377720
Improving Diagnosis in Health Care by National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care Pdf
Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Meta-Regression Analysis in Economics and Business by T.D. Stanley,Hristos Doucouliagos Pdf
The purpose of this book is to introduce novice researchers to the tools of meta-analysis and meta-regression analysis and to summarize the state of the art for existing practitioners. Meta-regression analysis addresses the rising "Tower of Babel" that current economics and business research has become. Meta-analysis is the statistical analysis of previously published, or reported, research findings on a given hypothesis, empirical effect, phenomenon, or policy intervention. It is a systematic review of all the relevant scientific knowledge on a specific subject and is an essential part of the evidence-based practice movement in medicine, education and the social sciences. However, research in economics and business is often fundamentally different from what is found in the sciences and thereby requires different methods for its synthesis—meta-regression analysis. This book develops, summarizes, and applies these meta-analytic methods.
Ecological Statistics by Gordon A. Fox,Simoneta Negrete-Yankelevich,Vinicio J. Sosa Pdf
An intermediate level text covering foundational ideas in statistics and their ecological application, including generalized linear and generalized mixed-effect models, as well as models allowing for mixtures, spatial or phylogenetic correlations, missing or censored data, and observational data; implemented in R and set within a contemporary research framework.