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Systematic Reviews in Health Care by Paul Glasziou,Les Irwig,Chris Bain,Graham Colditz Pdf
What do we do if different studies appear to give different answers? When applying research to questions for individual patients or for health policy, one of the challenges is interpreting such apparently conflicting research. A systematic review is a method to systematically identify relevant research, appraise its quality, and synthesize the results. The last two decades have seen increasing interest and developments in methods for doing high quality systematic reviews. Part I of this book provides a clear introduction to the concepts of reviewing, and lucidly describes the difficulties and traps to avoid. A unique feature of the book is its description, in Part II, of the different methods needed for different types of health care questions: frequency of disease, prognosis, diagnosis, risk, and management. As well as illustrative examples, there are exercises for each of the sections. This is essential reading for those interested in synthesizing health care research.
Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research
Author : Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Publisher : National Academies Press Page : 267 pages File Size : 49,5 Mb Release : 2011-07-20 Category : Medical ISBN : 9780309164252
Finding What Works in Health Care by Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Pdf
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
Systematic Reviews in Health Care by Matthias Egger,George Davey-Smith,Douglas Altman Pdf
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
Matthias Egger,Julian P. T. Higgins,George Davey Smith
Author : Matthias Egger,Julian P. T. Higgins,George Davey Smith Publisher : John Wiley & Sons Page : 612 pages File Size : 46,6 Mb Release : 2022-06-21 Category : Medical ISBN : 9781405160506
Systematic Reviews in Health Research by Matthias Egger,Julian P. T. Higgins,George Davey Smith Pdf
Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org) A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.
Systematic Reviews in Health Care by Matthias Egger,George Davey-Smith,Douglas Altman Pdf
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
How to Perform a Systematic Literature Review by Edward Purssell,Niall McCrae Pdf
The systematic review is a rigorous method of collating and synthesizing evidence from multiple studies, producing a whole greater than the sum of parts. This textbook is an authoritative and accessible guide to an activity that is often found overwhelming. The authors steer readers on a logical, sequential path through the process, taking account of the different needs of researchers, students and practitioners. Practical guidance is provided on the fundamentals of systematic reviewing and also on advanced techniques such as meta-analysis. Examples are given in each chapter, with a succinct glossary to support the text. This up-to-date, accessible textbook will satisfy the needs of students, practitioners and educators in the sphere of healthcare, and contribute to improving the quality of evidence-based practice. The authors will advise some freely available or inexpensive open source/access resources (such as PubMed, R and Zotero) to help students how to perform a systemic review, in particular those with limited resources.
Cochrane Handbook for Systematic Reviews of Interventions by Julian P. T. Higgins,Sally Green Pdf
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
Systematic Reviews to Answer Health Care Questions by Heidi D. Nelson Pdf
Systematic Evidence Reviews to Answer Health Care Questions is your most effective, A-to-Z guide to conducting thorough, comprehensive systematic reviews. By breaking down topics and essential steps, this volume teaches you how to form key questions, select evidence, and perform illuminating review not just in predictable circumstances, but when basic rules don’t apply—honing your ability to think critically and solve problems. You’ll learn how to define a review’s purpose and scope, develop research questions, build a team, and even manage your project to maximize efficacy. If you’re looking to refine your approach to systematic reviews, don’t just catalog and collect; use this powerful text to evaluate, synthesize, and deliver results that will help shape the health care industry. FEATURES Presented in standard format throughout to allow for more practical, easy to read approach Provides useful instruction on how to conduct a high-quality systematic review that meets the recent standards of the Institute of Medicine Accessible, concise information about the state-of-the-art methods of systematic review, from key question formulation to assessing the quality of included studies and reporting results Illustrated throughout with real-world examples from systematic reviews that have been used to inform practice guidelines and health policy
Institute of Medicine,Board on Health Care Services,Committee on Reviewing Evidence to Identify Highly Effective Clinical Services
Author : Institute of Medicine,Board on Health Care Services,Committee on Reviewing Evidence to Identify Highly Effective Clinical Services Publisher : National Academies Press Page : 279 pages File Size : 50,5 Mb Release : 2008-05-29 Category : Medical ISBN : 9780309113564
Knowing What Works in Health Care by Institute of Medicine,Board on Health Care Services,Committee on Reviewing Evidence to Identify Highly Effective Clinical Services Pdf
There is currently heightened interest in optimizing health care through the generation of new knowledge on the effectiveness of health care services. The United States must substantially strengthen its capacity for assessing evidence on what is known and not known about "what works" in health care. Even the most sophisticated clinicians and consumers struggle to learn which care is appropriate and under what circumstances. Knowing What Works in Health Care looks at the three fundamental health care issues in the United States-setting priorities for evidence assessment, assessing evidence (systematic review), and developing evidence-based clinical practice guidelines-and how each of these contributes to the end goal of effective, practical health care systems. This book provides an overall vision and roadmap for improving how the nation uses scientific evidence to identify the most effective clinical services. Knowing What Works in Health Care gives private and public sector firms, consumers, health care professionals, benefit administrators, and others the authoritative, independent information required for making essential informed health care decisions.
U. S. Department Human Services,Agency for and Quality
Author : U. S. Department Human Services,Agency for and Quality Publisher : Createspace Independent Publishing Platform Page : 0 pages File Size : 45,9 Mb Release : 2013-05-17 Category : Decision making ISBN : 1484997239
Decision and Simulation Modeling in Systematic Reviews by U. S. Department Human Services,Agency for and Quality Pdf
PURPOSE: The purpose of this study is to provide guidance for determining when incorporating a decision-analytic model alongside a systemic review would be of added value for decision making purposes. The purpose of systematic reviews is to synthesize the current scientific literature on a particular topic in the form of evidence reports and technology assessments to assist public and private organizations in developing strategies that improve the quality of health care and decision making. However, there is often not enough evidence to fully address the questions that are relevant for decision makers. Decision models may provide added value alongside systematic reviews by adding a formal structure, which can be informed by the evidence. METHODS: Our framework is informed by two sets of interviews and a focus group discussion; literature reviews to summarize best modeling practices and to profile the modeling literature; and an exploration of the feasibility of developing a database of published models. We interviewed Evidence-based Practice Center (EPC) members, some of whom have successfully incorporated models in EPC reports, to document lessons learned from those experiences. We also interviewed members of the U.S. Preventive Services Task Force (USPSTF) and cancer modelers who were involved in the recent efforts to use modeling with a systematic review to update USPSTF cancer screening guidelines, to evaluate the process of conducting a simultaneous systematic review and modeling exercise, and to evaluate stakeholder-perceived needs and whether needs were met. We reviewed and summarized the literature on best practices for modeling. This was supplemented by a focus group discussion with modeling experts to elicit, characterize, and precisely qualify best practices in decision and simulation modeling. These included: model formulation and characterization, model development and construction, handling and presentation of modeling assumptions, definition and presentation of parameters, outcomes to incorporate into the model, model analysis, model testing, validation, and implementation (including results presentation and communication). We developed a profile of the current modeling literature by conducting a systematic review of the medical literature and the grey literature to document publications that used a decision model and for what purpose (e.g., disease of interest, interventions evaluated). We also developed a prototype database to serve as a preliminary step in developing a resource that could be used to determine if, and how many, models exist on a particular disease of interest. RESULTS: The resulting report consists of six chapters. Decision and Simulation Modeling Alongside Systematic Reviews provides an overview of models and describes the differences and synergies between systematic reviews and decision analysis. In Overview of Decision Models Used in Research, we provide a "scan" of the medical literature over the past 5 years in terms of the use of models in studies that compare intervention strategies using multiple sources of data. Use of Modeling in Systematic Reviews: The EPC Perspective documents the extent to which EPCs have incorporated models into data and presents results from key informant interviews with EPC members. We present a framework for deciding when a decision model can inform decisionmaking alongside a systematic review in Suggested Framework for Deciding When a Modeling Effort Should Be Added to a Systematic Review. Potential Modeling Resources explores several possible approaches to use when undertaking a modeling effort and discusses some of the challenges. Lastly, Best Practices for Decision and Simulation Modeling reviews the literature on best practices for modeling, supplemented by a focus group discussion with modeling experts, and lessons learned about the process of conducting a modeling exercise alongside a systematic review using recent experience with the USPSTF. CONCLUSIONS: We suggest a process for deciding when conducting a decision analysis in conjunction with a systematic review would be of value to decision makers.
An Introduction to Systematic Reviews by David Gough,Sandy Oliver,James Thomas Pdf
This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre.
Systematic Reviews in the Social Sciences by Mark Petticrew,Helen Roberts Pdf
Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all social science disciplines; It requires no previous knowledge, but takes the reader through the process stage by stage; Drawing on examples from such diverse fields as psychology, criminology, education, transport, social welfare, public health, and housing and urban policy, among others. Including detailed sections on assessing the quality of both quantitative, and qualitative research; searching for evidence in the social sciences; meta-analytic and other methods of evidence synthesis; publication bias; heterogeneity; and approaches to dissemination.
Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research
Author : Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Publisher : National Academies Press Page : 267 pages File Size : 51,5 Mb Release : 2011-06-20 Category : Medical ISBN : 9780309216715
Finding What Works in Health Care by Institute of Medicine,Board on Health Care Services,Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Pdf
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
Meta-Ethnography by George W. Noblit,R. Dwight Hare Pdf
How can ethnographic studies be generalized, in contrast to concentrating on the individual case? Noblit and Hare propose a new method for synthesizing from qualitative studies: meta-ethnography. After citing the criteria to be used in comparing qualitative research projects, the authors define the ways these can then be aggregated to create more cogent syntheses of research. Using examples from numerous studies ranging from ethnographic work in educational settings to the Mead-Freeman controversy over Samoan youth, Meta-Ethnography offers useful procedural advice from both comparative and cumulative analyses of qualitative data. This provocative volume will be read with interest by researchers and students in qualitative research methods, ethnography, education, sociology, and anthropology. "After defining metaphor and synthesis, these authors provide a step-by-step program that will allow the researcher to show similarity (reciprocal translation), difference (refutation), or similarity at a higher level (lines or argument synthesis) among sample studies....Contain(s) valuable strategies at a seldom-used level of analysis." --Contemporary Sociology "The authors made an important contribution by reframing how we think of ethnography comparison in a way that is compatible with the new developments in interpretive ethnography. Meta-Ethnography is well worth consulting for the problem definition it offers." --The Journal of Nervous and Mental Disease "This book had to be written and I am pleased it was. Someone needed to break the ice and offer a strategy for summarizing multiple ethnographic studies. Noblit and Hare have done a commendable job of giving the research community one approach for doing so. Further, no one else can now venture into this area of synthesizing qualitative studies without making references to and positioning themselves vis-a-vis this volume." -Educational Studies
