Computational Immunology

Author : Shyamasree Ghosh
Publisher : CRC Press
Page : 201 pages
File Size : 44,6 Mb
Release : 2020-01-31
Category : Medical
ISBN : 9781351023498

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Computational Immunology by Shyamasree Ghosh Pdf

Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Author : Josep Bassaganya-Riera
Publisher : Academic Press
Page : 210 pages
File Size : 41,6 Mb
Release : 2015-10-21
Category : Medical
ISBN : 9780128037157

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Computational Immunology by Josep Bassaganya-Riera Pdf

Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Author : Shyamasree Ghosh
Publisher : CRC Press
Page : 201 pages
File Size : 45,7 Mb
Release : 2020-01-31
Category : Medical
ISBN : 9781351023498

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Computational Immunology by Shyamasree Ghosh Pdf

Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Author : Carmen Molina-París,Grant Lythe
Publisher : Springer Nature
Page : 300 pages
File Size : 53,8 Mb
Release : 2021-01-04
Category : Medical
ISBN : 9783030572044

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Mathematical, Computational and Experimental T Cell Immunology by Carmen Molina-París,Grant Lythe Pdf

Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.

Author : Shyamasree Ghosh
Publisher : CRC Press
Page : 181 pages
File Size : 53,6 Mb
Release : 2020-01-31
Category : Medical
ISBN : 9781351023481

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Computational Immunology by Shyamasree Ghosh Pdf

Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Author : Luca Marchetti,Corrado Priami,Vo Hong Thanh
Publisher : Springer
Page : 238 pages
File Size : 47,7 Mb
Release : 2017-09-27
Category : Computers
ISBN : 9783319631134

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Simulation Algorithms for Computational Systems Biology by Luca Marchetti,Corrado Priami,Vo Hong Thanh Pdf

This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies. This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.

Author : Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain
Publisher : Frontiers Media SA
Page : 358 pages
File Size : 40,6 Mb
Release : 2020-01-30
Category : Electronic
ISBN : 9782889633883

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Methods and Applications of Computational Immunology by Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain Pdf

Author : Martina Husáková
Publisher : Tomáš Bruckner
Page : 174 pages
File Size : 41,8 Mb
Release : 2015-09-10
Category : Computers
ISBN : 9788087924020

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Conceptual Modelling in Computational Immunology by Martina Husáková Pdf

Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Author : Dominik Wodarz
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 41,8 Mb
Release : 2007-04-05
Category : Mathematics
ISBN : 9780387687339

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Killer Cell Dynamics by Dominik Wodarz Pdf

This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

Author : Christian Schönbach,Shoba Ranganathan,Vladimir Brusic
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 48,8 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9780387729688

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Immunoinformatics by Christian Schönbach,Shoba Ranganathan,Vladimir Brusic Pdf

In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

Author : Röbbe Wünschiers
Publisher : Springer Science & Business Media
Page : 453 pages
File Size : 50,7 Mb
Release : 2013-01-30
Category : Science
ISBN : 9783642347498

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Computational Biology by Röbbe Wünschiers Pdf

This greatly expanded 2nd edition provides a practical introduction to - data processing with Linux tools and the programming languages AWK and Perl - data management with the relational database system MySQL, and - data analysis and visualization with the statistical computing environment R for students and practitioners in the life sciences. Although written for beginners, experienced researchers in areas involving bioinformatics and computational biology may benefit from numerous tips and tricks that help to process, filter and format large datasets. Learning by doing is the basic concept of this book. Worked examples illustrate how to employ data processing and analysis techniques, e.g. for - finding proteins potentially causing pathogenicity in bacteria, - supporting the significance of BLAST with homology modeling, or - detecting candidate proteins that may be redox-regulated, on the basis of their structure. All the software tools and datasets used are freely available. One section is devoted to explaining setup and maintenance of Linux as an operating system independent virtual machine. The author's experiences and knowledge gained from working and teaching in both academia and industry constitute the foundation for this practical approach.

Author : Shyamasree Ghosh
Publisher : CRC Press
Page : 312 pages
File Size : 48,5 Mb
Release : 2019-10-14
Category : Medical
ISBN : 9781351025539

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Computational Immunology by Shyamasree Ghosh Pdf

The immune system is highly complex system with large number of macromolecules, signaling pathways, protein-protein interactions, and gene expressions. Studies from genomics, transcriptomics, metabolomics are generating huge high throughput data that needs to be analyzed for understanding the Immune system in Health and Disease. Computational approaches arehelping in understanding the study of complex biology of immunology and thereby enabling design of therapeutic strategies in diseases like infectious diseases, immunodeficiency, allergic, hypersensitive, autoimmune disorders and diseases like Cancer, HIV etc. Computational Immunology: Basics highlights the basics of the immune system and function in health and disease. This book offers comprehensive coverage of the most essential topics, including Overview of Immunology and computational Immunology Immune organs and cells, antigen, antibody, B, cell, T cell Antigen Processing and presentation Diseases due to abnormalities of the immune system Cancer Biology Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Author : Ole Lund,Morten Nielsen,Claus Lundegaard,Can Kesmir,Søren Brunak
Publisher : MIT Press
Page : 335 pages
File Size : 48,5 Mb
Release : 2024-02-06
Category : Computers
ISBN : 9780262551120

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Immunological Bioinformatics by Ole Lund,Morten Nielsen,Claus Lundegaard,Can Kesmir,Søren Brunak Pdf

Using bioinformatics methods to generate a systems-level view of the immune system; description of the main biological concepts and the new data-driven algorithms. Despite the fact that advanced bioinformatics methodologies have not been used as extensively in immunology as in other subdisciplines within biology, research in immunological bioinformatics has already developed models of components of the immune system that can be combined and that may help develop therapies, vaccines, and diagnostic tools for such diseases as AIDS, malaria, and cancer. In a broader perspective, specialized bioinformatics methods in immunology make possible for the first time a systems-level understanding of the immune system. The traditional approaches to immunology are reductionist, avoiding complexity but providing detailed knowledge of a single event, cell, or molecular entity. Today, a variety of experimental bioinformatics techniques connected to the sequencing of the human genome provides a sound scientific basis for a comprehensive description of the complex immunological processes. This book offers a description of bioinformatics techniques as they are applied to immunology, including a succinct account of the main biological concepts for students and researchers with backgrounds in mathematics, statistics, and computer science as well as explanations of the new data-driven algorithms in the context of biological data that will be useful for immunologists, biologists, and biochemists working on vaccine design. In each chapter the authors show interesting biological insights gained from the bioinformatics approach. The book concludes by explaining how all the methods presented in the book can be integrated to identify immunogenic regions in microorganisms and host genomes.

Author : Dipankar Dasgupta,Fernando Nino
Publisher : CRC Press
Page : 298 pages
File Size : 47,6 Mb
Release : 2008-09-12
Category : Computers
ISBN : 9781420065466

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Immunological Computation by Dipankar Dasgupta,Fernando Nino Pdf

Clearly, nature has been very effective in creating organisms that are capable of protecting themselves against a wide variety of pathogens such as bacteria, fungi, and parasites. The powerful information-processing capabilities of the immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive nature prov

Author : Karthik Raman
Publisher : CRC Press
Page : 359 pages
File Size : 48,9 Mb
Release : 2021-05-30
Category : Computers
ISBN : 9780429944529

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An Introduction to Computational Systems Biology by Karthik Raman Pdf

Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling