Computational Modelling Of The Brain

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Computational Models of Brain and Behavior

Author : Ahmed A. Moustafa
Publisher : John Wiley & Sons
Page : 586 pages
File Size : 45,5 Mb
Release : 2017-11-13
Category : Psychology
ISBN : 9781119159063

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Computational Models of Brain and Behavior by Ahmed A. Moustafa Pdf

A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Principles of Computational Modelling in Neuroscience

Author : David Sterratt,Bruce Graham,Andrew Gillies,Gaute Einevoll,David Willshaw
Publisher : Cambridge University Press
Page : 553 pages
File Size : 52,7 Mb
Release : 2023-10-05
Category : Science
ISBN : 9781108483148

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Principles of Computational Modelling in Neuroscience by David Sterratt,Bruce Graham,Andrew Gillies,Gaute Einevoll,David Willshaw Pdf

Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.

Computational Modelling of the Brain

Author : Michele Giugliano,Mario Negrello,Daniele Linaro
Publisher : Springer Nature
Page : 361 pages
File Size : 46,9 Mb
Release : 2022-04-26
Category : Medical
ISBN : 9783030894399

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Computational Modelling of the Brain by Michele Giugliano,Mario Negrello,Daniele Linaro Pdf

This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Brain and Human Body Modeling

Author : Sergey Makarov,Marc Horner,Gregory Noetscher
Publisher : Springer Nature
Page : 398 pages
File Size : 41,7 Mb
Release : 2019-08-27
Category : Technology & Engineering
ISBN : 9783030212933

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Brain and Human Body Modeling by Sergey Makarov,Marc Horner,Gregory Noetscher Pdf

This open access book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner. Describes construction and application of computational human models including anatomically detailed and subject specific models; Explains new practices in computational human modeling for neuroelectromagnetics, electromagnetic safety, and exposure evaluations; Includes a survey of modern applications for which computational human models are critical; Describes cellular-level interactions between the human body and electromagnetic fields.

Computational Modelling in Behavioural Neuroscience

Author : Dietmar Heinke,Eirini Mavritsaki
Publisher : Psychology Press
Page : 375 pages
File Size : 40,9 Mb
Release : 2009-04-03
Category : Medical
ISBN : 9781135430030

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Computational Modelling in Behavioural Neuroscience by Dietmar Heinke,Eirini Mavritsaki Pdf

This book represents the state-of-the-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience.

The Computational Brain

Author : Patricia Smith Churchland,Terrence Joseph Sejnowski
Publisher : MIT Press
Page : 564 pages
File Size : 46,7 Mb
Release : 1992
Category : Anatomy
ISBN : 0262531208

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The Computational Brain by Patricia Smith Churchland,Terrence Joseph Sejnowski Pdf

"The Computational Brain addresses a broad audience: neuroscientists, computer scientists, cognitive scientists, and philosophers. It is written for both the expert and novice. A basic overview of neuroscience and computational theory is provided, followed by a study of some of the most recent and sophisticated modeling work in the context of relevant neurobiological research. Technical terms are clearly explained in the text, and definitions are provided in an extensive glossary. The appendix contains a précis of neurobiological techniques."--Jacket.

The Computational Brain, 25th Anniversary Edition

Author : Patricia S. Churchland,Terrence J. Sejnowski
Publisher : MIT Press
Page : 569 pages
File Size : 48,8 Mb
Release : 2016-11-04
Category : Science
ISBN : 9780262533393

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The Computational Brain, 25th Anniversary Edition by Patricia S. Churchland,Terrence J. Sejnowski Pdf

An anniversary edition of the classic work that influenced a generation of neuroscientists and cognitive neuroscientists. Before The Computational Brain was published in 1992, conceptual frameworks for brain function were based on the behavior of single neurons, applied globally. In The Computational Brain, Patricia Churchland and Terrence Sejnowski developed a different conceptual framework, based on large populations of neurons. They did this by showing that patterns of activities among the units in trained artificial neural network models had properties that resembled those recorded from populations of neurons recorded one at a time. It is one of the first books to bring together computational concepts and behavioral data within a neurobiological framework. Aimed at a broad audience of neuroscientists, computer scientists, cognitive scientists, and philosophers, The Computational Brain is written for both expert and novice. This anniversary edition offers a new preface by the authors that puts the book in the context of current research. This approach influenced a generation of researchers. Even today, when neuroscientists can routinely record from hundreds of neurons using optics rather than electricity, and the 2013 White House BRAIN initiative heralded a new era in innovative neurotechnologies, the main message of The Computational Brain is still relevant.

Computational Modelling in Behavioural Neuroscience

Author : Dietmar Heinke,Eirini Mavritsaki
Publisher : Psychology Press
Page : 475 pages
File Size : 51,6 Mb
Release : 2009-04-03
Category : Psychology
ISBN : 9781135430023

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Computational Modelling in Behavioural Neuroscience by Dietmar Heinke,Eirini Mavritsaki Pdf

Classically, behavioural neuroscience theorizes about experimental evidence in a qualitative way. However, more recently there has been an increasing development of mathematical and computational models of experimental results, and in general these models are more clearly defined and more detailed than their qualitative counter parts. These new computational models can be set up so that they are consistent with both single neuron and whole-system levels of operation, allowing physiological results to be meshed with behavioural data – thus closing the gap between neurophysiology and human behaviour. There is considerable diversity between models with respect to the methodology of designing a model, the degree to which neurophysiological processes are taken into account and the way data (behavioural, electrophysiological, etc) constrains a model. This book presents examples of this diversity and in doing so represents the state-of-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience. Based on talks given at the third Behavioural Brain Sciences Symposium, held at the Behavioural Brain Sciences Centre, University of Birmingham, in May 2007, the book appeals to a broad audience, from postgraduate students beginning to work in the field to experienced experimenters interested in an overview.

Computational Explorations in Cognitive Neuroscience

Author : Randall C. O'Reilly,Yuko Munakata
Publisher : MIT Press
Page : 540 pages
File Size : 43,9 Mb
Release : 2000-08-28
Category : Medical
ISBN : 0262650541

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Computational Explorations in Cognitive Neuroscience by Randall C. O'Reilly,Yuko Munakata Pdf

This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the computational cognitive neuroscience. The goal of computational cognitive neuroscience is to understand how the brain embodies the mind by using biologically based computational models comprising networks of neuronlike units. This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the field. The neural units in the simulations use equations based directly on the ion channels that govern the behavior of real neurons, and the neural networks incorporate anatomical and physiological properties of the neocortex. Thus the text provides the student with knowledge of the basic biology of the brain as well as the computational skills needed to simulate large-scale cognitive phenomena. The text consists of two parts. The first part covers basic neural computation mechanisms: individual neurons, neural networks, and learning mechanisms. The second part covers large-scale brain area organization and cognitive phenomena: perception and attention, memory, language, and higher-level cognition. The second part is relatively self-contained and can be used separately for mechanistically oriented cognitive neuroscience courses. Integrated throughout the text are more than forty different simulation models, many of them full-scale research-grade models, with friendly interfaces and accompanying exercises. The simulation software (PDP++, available for all major platforms) and simulations can be downloaded free of charge from the Web. Exercise solutions are available, and the text includes full information on the software.

Brain and Human Body Modeling 2020

Author : Sergey N. Makarov
Publisher : Springer Nature
Page : 395 pages
File Size : 48,8 Mb
Release : 2021
Category : Biomedical engineering
ISBN : 9783030456238

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Brain and Human Body Modeling 2020 by Sergey N. Makarov Pdf

The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.

Computational Modeling of Cognition and Behavior

Author : Simon Farrell,Stephan Lewandowsky
Publisher : Cambridge University Press
Page : 485 pages
File Size : 45,6 Mb
Release : 2018-02-22
Category : Psychology
ISBN : 9781107109995

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Computational Modeling of Cognition and Behavior by Simon Farrell,Stephan Lewandowsky Pdf

This book presents an integrated framework for developing and testing computational models in psychology and related disciplines. Researchers and students are given the knowledge and tools to interpret models published in their area, as well as to develop, fit, and test their own models.

Principles of Computational Modelling in Neuroscience

Author : David Sterratt,Bruce Graham,Andrew Gillies,David Willshaw
Publisher : Cambridge University Press
Page : 403 pages
File Size : 52,7 Mb
Release : 2011-06-30
Category : Medical
ISBN : 9781139500791

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Principles of Computational Modelling in Neuroscience by David Sterratt,Bruce Graham,Andrew Gillies,David Willshaw Pdf

The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.

Models of the Mind

Author : Grace Lindsay
Publisher : Bloomsbury Publishing
Page : 401 pages
File Size : 54,5 Mb
Release : 2021-03-04
Category : Science
ISBN : 9781472966452

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Models of the Mind by Grace Lindsay Pdf

The human brain is made up of 85 billion neurons, which are connected by over 100 trillion synapses. For more than a century, a diverse array of researchers searched for a language that could be used to capture the essence of what these neurons do and how they communicate – and how those communications create thoughts, perceptions and actions. The language they were looking for was mathematics, and we would not be able to understand the brain as we do today without it. In Models of the Mind, author and computational neuroscientist Grace Lindsay explains how mathematical models have allowed scientists to understand and describe many of the brain's processes, including decision-making, sensory processing, quantifying memory, and more. She introduces readers to the most important concepts in modern neuroscience, and highlights the tensions that arise when the abstract world of mathematical modelling collides with the messy details of biology. Each chapter of Models of the Mind focuses on mathematical tools that have been applied in a particular area of neuroscience, progressing from the simplest building block of the brain – the individual neuron – through to circuits of interacting neurons, whole brain areas and even the behaviours that brains command. In addition, Grace examines the history of the field, starting with experiments done on frog legs in the late eighteenth century and building to the large models of artificial neural networks that form the basis of modern artificial intelligence. Throughout, she reveals the value of using the elegant language of mathematics to describe the machinery of neuroscience.

Multiscale Models of Brain Disorders

Author : Vassilis Cutsuridis
Publisher : Springer
Page : 0 pages
File Size : 52,6 Mb
Release : 2020-10-24
Category : Medical
ISBN : 3030188329

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Multiscale Models of Brain Disorders by Vassilis Cutsuridis Pdf

This book focuses on our current understanding of brain dynamics in various brain disorders (e.g. epilepsy, Alzheimer’s and Parkinson’s disease) and how the multi-scale, multi-level tools of computational neuroscience can enhance this understanding. In recent years, there have been significant advances in the study of the dynamics of the disordered brain at both the microscopic and the macroscopic levels. This understanding can be furthered by the application of multi-scale computational models as integrative principles that may link single neuron dynamics and the dynamics of local and distant brain regions observed using human EEG, ERPs, MEG, LFPs and fMRI. Focusing on the computational models that are used to study movement, memory and cognitive disorders as well as epilepsy and consciousness related diseases, the book brings together physiologists and anatomists investigating cortical circuits; cognitive neuroscientists studying brain dynamics and behavior by means of EEG and functional magnetic resonance imaging (fMRI); and computational neuroscientists using neural modeling techniques to explore local and large-scale disordered brain dynamics. Covering topics that have a significant impact on the field of medicine, neuroscience and computer science, the book appeals to a diverse group of investigators.

Neural and Computational Modeling of Movement Control

Author : Ning Lan,Vincent C. K. Cheung,Simon C. Gandevia
Publisher : Frontiers Media SA
Page : 180 pages
File Size : 53,6 Mb
Release : 2017-04-17
Category : Electronic book
ISBN : 9782889451302

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Neural and Computational Modeling of Movement Control by Ning Lan,Vincent C. K. Cheung,Simon C. Gandevia Pdf

In the study of sensorimotor systems, an important research goal has been to understand the way neural networks in the spinal cord and brain interact to control voluntary movement. Computational modeling has provided insight into the interaction between centrally generated commands, proprioceptive feedback signals and the biomechanical responses of the moving body. Research in this field is also driven by the need to improve and optimize rehabilitation after nervous system injury and to devise biomimetic methods of control in robotic devices. This research topic is focused on efforts dedicated to identify and model the neuromechanical control of movement. Neural networks in the brain and spinal cord are known to generate patterned activity that mediates coordinated activation of multiple muscles in both rhythmic and discrete movements, e.g. locomotion and reaching. Commands descending from the higher centres in the CNS modulate the activity of spinal networks, which control movement on the basis of sensory feedback of various types, including that from proprioceptive afferents. The computational models will continue to shed light on the central strategies and mechanisms of sensorimotor control and learning. This research topic demonstrated that computational modeling is playing a more and more prominent role in the studies of postural and movement control. With increasing ability to gather data from all levels of the neuromechanical sensorimotor systems, there is a compelling need for novel, creative modeling of new and existing data sets, because the more systematic means to extract knowledge and insights about neural computations of sensorimotor systems from these data is through computational modeling. While models should be based on experimental data and validated with experimental evidence, they should also be flexible to provide a conceptual framework for unifying diverse data sets, to generate new insights of neural mechanisms, to integrate new data sets into the general framework, to validate or refute hypotheses and to suggest new testable hypotheses for future experimental investigation. It is thus expected that neural and computational modeling of the sensorimotor system should create new opportunities for experimentalists and modelers to collaborate in a joint endeavor to advance our understanding of the neural mechanisms for postural and movement control. The editors would like to thank Professor Arthur Prochazka, who helped initially to set up this research topic, and all authors who contributed their articles to this research topic. Our appreciation also goes to the reviewers, who volunteered their time and effort to help achieve the goal of this research topic. We would also like to thank the staff members of editorial office of Frontiers in Computational Neuroscience for their expertise in the process of manuscript handling, publishing, and in bringing this ebook to the readers. The support from the Editor-in-Chief, Dr. Misha Tsodyks and Dr. Si Wu is crucial for this research topic to come to a successful conclusion. We are indebted to Dr. Si Li and Ms. Ting Xu, whose assistant is important for this ebook to become a reality. Finally, this work is supported in part by grants to Dr. Ning Lan from the Ministry of Science and Technology of China (2011CB013304), the Natural Science Foundation of China (No. 81271684, No. 61361160415, No. 81630050), and the Interdisciplinary Research Grant cross Engineering and Medicine by Shanghai Jiao Tong University (YG20148D09). Dr. Vincent Cheung is supported by startup funds from the Faculty of Medicine of The Chinese University of Hong Kong. Guest Associate Editors Ning Lan, Vincent Cheung, and Simon Gandevia