Computational Systems Bioinformatics Methods And Biomedical Applications

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Computational Systems Bioinformatics

Author : Xiaobo Zhou,Stephen T. C. Wong
Publisher : World Scientific
Page : 398 pages
File Size : 42,6 Mb
Release : 2008
Category : Science
ISBN : 9789812707048

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Computational Systems Bioinformatics by Xiaobo Zhou,Stephen T. C. Wong Pdf

Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields. This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.

Computational Systems Bioinformatics - Methods And Biomedical Applications

Author : Wong Stephen Tin Chi,Zhou Xiaobo
Publisher : World Scientific Publishing Company
Page : 400 pages
File Size : 46,5 Mb
Release : 2008-01-02
Category : Science
ISBN : 9789813106994

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Computational Systems Bioinformatics - Methods And Biomedical Applications by Wong Stephen Tin Chi,Zhou Xiaobo Pdf

Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields.This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.

Computational Systems Bioinformatics

Author : Peter Markstein,Ying Xu,Life Sciences Society
Publisher : World Scientific
Page : 472 pages
File Size : 41,8 Mb
Release : 2007
Category : Computers
ISBN : 9781860948732

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Computational Systems Bioinformatics by Peter Markstein,Ying Xu,Life Sciences Society Pdf

This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. Abstracts from the keynote addresses and invited talks are also included. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Sample Chapter(s). Chapter 1: Whole-Genome Analysis of Dorsal Gradient Thresholds in the Drosophila Embryo (102 KB). Contents: Learning Predictive Models of Gene Regulation (C Leslie); Algorithms for Selecting Breakpoint Locations to Optimize Diversity in Protein Engineering by Site-Directed Protein Recombination (W Zheng et al.); Cancer Molecular Pattern Discovery by Subspace Consensus Kernel Classification (X Han); Transcriptional Profiling of Definitive Endoderm Derived from Human Embryonic Stem Cells (H Liu et al.); A Markov Model Based Analysis of Stochastic Biochemical Systems (P Ghosh et al.); Clustering of Main Orthologs for Multiple Genomes (Z Fu & T Jiang); Extraction, Quantification and Visualization of Protein Pockets (X Zhang & C Bajaj); Consensus Contact Prediction by Linear Programming (X Gao et al.); An Active Visual Search Interface for Medline (W Xuan et al.); Exact and Heuristic Algorithms for Weighted Cluster Editing (S Rahmann et al.); Reconcilation with Non-binary Species Trees (B Vernot et al.); and other papers. Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. Graduate researchers in bioinformatics and computational biology.

Computational Systems Bioinformatics

Author : Peter Markstein,Ying Xu
Publisher : World Scientific
Page : 416 pages
File Size : 40,8 Mb
Release : 2006-07-28
Category : Computers
ISBN : 9781908979476

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Computational Systems Bioinformatics by Peter Markstein,Ying Xu Pdf

This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks. The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Contents:Exploring the Ocean's Microbes: Sequencing the Seven Seas (M E Frazier et al.)Protein Network Comparative Genomics (T Ideker)Bioinformatics at Microsoft Research (S Mercer)Protein Fold Recognition Using Gradient Boost Algorithm (F Jiao et al.)Efficient Annotation of Non-Coding RNA Structures Including Pseudoknots via Automated Filters (C Liu et al.)Efficient Generalized Matrix Approximations for Biomarker Discovery and Visualization in Gene Expression Data (W Li et al.)Sorting Genomes by Translocations and Deletions (X Qi et al.)Detection of Cleavage Sites for HIV-1 Protease in Native Proteins (L You)Identifying Biological Pathways via Phase Decomposition and Profile Extraction (Y Zhang & Z Deng)Complexity and Scoring Function of MS/MS Peptide De Novo Sequencing (C Xu & B Ma)Simulating In Vitro Epithelial Morphogenesis in Multiple Environments (M R Grant et al.)and other papers Readership: Research and application community in bioinformatics, systems biology, medicine, pharmacology and biotechnology. A useful reference for graduate researchers in bioinformatics and computational biology. Keywords:Bioinformatics;Computational Biology;Genomics;Proteomics;Structural Biology;Biological Pathways;Phylogenetics;Systems BiologyKey Features:The CSB meetings accepts only the highest quality research paper, with a paper-acceptance rate of below 20%The CSB meeting represents an unique bioinformatics conference in which papers blend bioinformatic tool development with in silico biologyCSB meetings have become one of the most well attended bioinformatics conferencesCSB proceedings are indexed by Medline

Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances

Author : Lecca, Paola
Publisher : IGI Global
Page : 471 pages
File Size : 55,5 Mb
Release : 2011-12-31
Category : Medical
ISBN : 9781613504369

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Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances by Lecca, Paola Pdf

The convergence of biology and computer science was initially motivated by the need to organize and process a growing number of biological observations resulting from rapid advances in experimental techniques. Today, however, close collaboration between biologists, biochemists, medical researchers, and computer scientists has also generated remarkable benefits for the field of computer science. Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data. The book covers three subject areas: bioinformatics, computational biology, and computational systems biology. It focuses on recent, systemic approaches in computer science and mathematics that have been used to model, simulate, and more generally, experiment with biological phenomena at any scale.

Systems Biology and Bioinformatics

Author : Kayvan Najarian,Siamak Najarian,Shahriar Gharibzadeh,Christopher N. Eichelberger
Publisher : CRC Press
Page : 190 pages
File Size : 42,9 Mb
Release : 2009-04-13
Category : Medical
ISBN : 9781439882948

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Systems Biology and Bioinformatics by Kayvan Najarian,Siamak Najarian,Shahriar Gharibzadeh,Christopher N. Eichelberger Pdf

The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods

Computational Systems Bioinformatics

Author : Peter Markstein,Ying Xu
Publisher : World Scientific
Page : 356 pages
File Size : 45,8 Mb
Release : 2008-08-01
Category : Mathematics
ISBN : 9781908978707

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Computational Systems Bioinformatics by Peter Markstein,Ying Xu Pdf

This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field. Contents: Voting Algorithms for the Motif Finding Problem (X-W Liu et al.)MSDash: Mass Spectrometry Database and Search (Z Wu et al.)GaborLocal: Peak Detection in Mass Spectrum by Gabor Filters and Gaussian Local Maxima (N Nguyen et al.)Designing Secondary Structure Profiles for Fast ncRNA Identification (Y Sun & J Buhler)Iterative Non-sequential Protein Structural Alignment (S Salem & M J Zaki)Consistent Alignment of Metabolic Pathways Without Abstraction (F Ay et al.)On the Accurate Construction of Consensus Genetic Maps (Y-H Wu et al.)Graph Wavelet Alignment Kernels for Drug Virtual Screening (A Smalter et al.)and other papers Readership: Graduate students, postdoctoral fellows, researchers, and practitioners in the field of bioinformatics and systems biology; biotech and pharmaceutical companies; computational scientists and engineers interested in biology. Keywords:Bioinformatics;Computational Systems Biology;Computational Techniques;Systems Biology ProblemsKey Features:The CSB meetings accept only the highest-quality research papers, with a paper-acceptance rate of below 20%The CSB meetings represent a unique bioinformatics conference in which papers blend bioinformatic tool development with in silico biologyCSB meetings have become one of the most well-attended bioinformatics conferencesCSB proceedings are indexed by Medline

Computational Systems Bioinformatics

Author : Peter Markstein,Ying Xu
Publisher : World Scientific
Page : 355 pages
File Size : 54,7 Mb
Release : 2008
Category : Science
ISBN : 9781848162631

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Computational Systems Bioinformatics by Peter Markstein,Ying Xu Pdf

This proceedings volume contains 29 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.

Computational Systems Biology

Author : Andres Kriete,Roland Eils
Publisher : Academic Press
Page : 409 pages
File Size : 55,7 Mb
Release : 2006
Category : Medical
ISBN : 012088786X

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Computational Systems Biology by Andres Kriete,Roland Eils Pdf

Computational systems biology is a field that aims to develop a systems level understanding of biological processes using computational techniques. This book presents a compendium of the state-of-the-art in this new era of biological understanding. The contributors review bioinformation engineering and data integration technologies along with biomedical applications. Different computational approaches to model and simulate biological systems are discussed. Current computational research efforts, comprehensively covered in this volume, are focused on regulatory, signaling and metabolic networks. New concepts for computer representations on multi-scales predicting emergent properties of biological systems are introduced.

Practical Applications of Computational Biology and Bioinformatics, 12th International Conference

Author : Florentino Fdez-Riverola,Mohd Saberi Mohamad,Miguel Rocha,Juan F. De Paz,Pascual González
Publisher : Springer
Page : 226 pages
File Size : 45,7 Mb
Release : 2018-08-16
Category : Technology & Engineering
ISBN : 9783319987026

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Practical Applications of Computational Biology and Bioinformatics, 12th International Conference by Florentino Fdez-Riverola,Mohd Saberi Mohamad,Miguel Rocha,Juan F. De Paz,Pascual González Pdf

This book introduces the latest international research in the fields of bioinformatics and computational biology. It includes various studies in the area of machine learning in bioinformatics, systems biology, omics data analysis and mining, biomedical applications and sequences, which were selected by an international committee and presented at the 12th International Conference on Practical Applications of Computational Biology & Bioinformatics held in Toledo in June 2018.

Transactions on Computational Systems Biology VI

Author : Gordon Plotkin
Publisher : Springer Science & Business Media
Page : 253 pages
File Size : 49,7 Mb
Release : 2006-11-27
Category : Computers
ISBN : 9783540457794

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Transactions on Computational Systems Biology VI by Gordon Plotkin Pdf

The 5th Transactions on Computational Systems Biology volume, edited by Gordon Plotkin, features carefully selected and enhanced contributions initially presented at the 2005 IEEE International Conference on Granular Computing. The 9 papers selected for this special issue discuss various aspects of computational methods, algorithm and techniques in bioinformatics such as gene expression analysis, biomedical literature mining and natural language processing, protein structure prediction, biological database management and biomedical information retrieval.

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology

Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Page : 592 pages
File Size : 51,6 Mb
Release : 2016-03-25
Category : Computers
ISBN : 9780128042595

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Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology by Hamid R Arabnia,Quoc Nam Tran Pdf

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

Bioinformatics and Systems Biology

Author : Frederick Marcus
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 45,5 Mb
Release : 2008-07-22
Category : Science
ISBN : 9783540783534

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Bioinformatics and Systems Biology by Frederick Marcus Pdf

Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.

Bioinformatics and Computational Biology

Author : Tiratha Raj Singh,Hemraj Saini,Moacyr Comar Junior
Publisher : CRC Press
Page : 460 pages
File Size : 51,5 Mb
Release : 2023-12-13
Category : Computers
ISBN : 9781003813231

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Bioinformatics and Computational Biology by Tiratha Raj Singh,Hemraj Saini,Moacyr Comar Junior Pdf

Bioinformatics and Computational Biology: Technological Advancements, Applications and Opportunities is an invaluable resource for general and applied researchers who analyze biological data that is generated, at an unprecedented rate, at the global level. After careful evaluation of the requirements for current trends in bioinformatics and computational biology, it is anticipated that the book will provide an insightful resource to the academic and scientific community. Through a myriad of computational resources, algorithms, and methods, it equips readers with the confidence to both analyze biological data and estimate predictions. The book offers comprehensive coverage of the most essential and emerging topics: Cloud-based monitoring of bioinformatics multivariate data with cloud platforms Machine learning and deep learning in bioinformatics Quantum machine learning for biological applications Integrating machine learning strategies with multiomics to augment prognosis in chronic diseases Biomedical engineering Next generation sequencing techniques and applications Computational systems biology and molecular evolution While other books may touch on some of the same issues and nuances of biological data analysis, they neglect to feature bioinformatics and computational biology exclusively, and as exhaustively. This book's abundance of several subtopics related to almost all of the regulatory activities of biomolecules from where real data is being generated brings an added dimension.

Computational Methods With Applications In Bioinformatics Analysis

Author : Tsai Jeffrey J P,Ng Ka-lok
Publisher : World Scientific
Page : 232 pages
File Size : 47,8 Mb
Release : 2017-06-09
Category : Computers
ISBN : 9789813207998

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Computational Methods With Applications In Bioinformatics Analysis by Tsai Jeffrey J P,Ng Ka-lok Pdf

This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms. The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics. The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.