Systems Biology And Bioinformatics

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Computational Biology and Bioinformatics

Ka-Chun Wong
Computational Biology and Bioinformatics Book PDF

Author : Ka-Chun Wong
Publisher : CRC Press
Page : 425 pages
File Size : 48,6 Mb
Release : 2016-04-27
Category : Science
ISBN : 9781498725002

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Computational Biology and Bioinformatics by Ka-Chun Wong Pdf

The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical skills and computational methods which are collectively called computational biology and bioinformatics. Without them, the biotechnology-output data by itself is raw and perhaps meaningless. To raise such awareness, we have collected the state-of-the-art research works in computational biology and bioinformatics with a thematic focus on gene regulation in this book. This book is designed to be self-contained and comprehensive, targeting senior undergraduates and junior graduate students in the related disciplines such as bioinformatics, computational biology, biostatistics, genome science, computer science, applied data mining, applied machine learning, life science, biomedical science, and genetics. In addition, we believe that this book will serve as a useful reference for both bioinformaticians and computational biologists in the post-genomic era.

Bioinformatics for Systems Biology

Stephen Krawetz
Bioinformatics for Systems Biology Book PDF

Author : Stephen Krawetz
Publisher : Springer Science & Business Media
Page : 639 pages
File Size : 51,5 Mb
Release : 2008-12-11
Category : Science
ISBN : 9781597454407

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Bioinformatics for Systems Biology by Stephen Krawetz Pdf

Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.

Systems Biology and Bioinformatics

Kayvan Najarian,Siamak Najarian,Shahriar Gharibzadeh,Christopher N. Eichelberger
Systems Biology and Bioinformatics Book PDF

Author : Kayvan Najarian,Siamak Najarian,Shahriar Gharibzadeh,Christopher N. Eichelberger
Publisher : CRC Press
Page : 190 pages
File Size : 40,7 Mb
Release : 2009-04-13
Category : Medical
ISBN : 9781439882948

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Systems Biology and Bioinformatics by Kayvan Najarian,Siamak Najarian,Shahriar Gharibzadeh,Christopher N. Eichelberger Pdf

The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology

Hamid R Arabnia,Quoc Nam Tran
Emerging Trends in Computational Biology Bioinformatics and Systems Biology Book PDF

Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Page : 670 pages
File Size : 41,8 Mb
Release : 2015-08-11
Category : Computers
ISBN : 9780128026465

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Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology by Hamid R Arabnia,Quoc Nam Tran Pdf

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Bioinformatics and Systems Biology

Frederick Marcus
Bioinformatics and Systems Biology Book PDF

Author : Frederick Marcus
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 48,6 Mb
Release : 2008-07-22
Category : Science
ISBN : 9783540783534

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Bioinformatics and Systems Biology by Frederick Marcus Pdf

Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.

Encyclopedia of Bioinformatics and Computational Biology

Anonim
Encyclopedia of Bioinformatics and Computational Biology Book PDF

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 51,9 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Bioinformatics and Computational Biology

Basant K. Tiwary
Bioinformatics and Computational Biology Book PDF

Author : Basant K. Tiwary
Publisher : Springer Nature
Page : 239 pages
File Size : 47,7 Mb
Release : 2021-11-23
Category : Medical
ISBN : 9789811642418

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Bioinformatics and Computational Biology by Basant K. Tiwary Pdf

This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.

Biological Modeling and Simulation

Russell Schwartz
Biological Modeling and Simulation Book PDF

Author : Russell Schwartz
Publisher : MIT Press
Page : 403 pages
File Size : 52,9 Mb
Release : 2008-07-25
Category : Science
ISBN : 9780262195843

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Biological Modeling and Simulation by Russell Schwartz Pdf

A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.

Systems Biology

Bor-Sen Chen,Chia-Chou Wu
Systems Biology Book PDF

Author : Bor-Sen Chen,Chia-Chou Wu
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 54,5 Mb
Release : 2014
Category : Systems biology
ISBN : 1633215881

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Systems Biology by Bor-Sen Chen,Chia-Chou Wu Pdf

This text not only describes the current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers but also discusses challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering.

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology

Hamid R Arabnia,Quoc Nam Tran
Emerging Trends in Applications and Infrastructures for Computational Biology Bioinformatics and Systems Biology Book PDF

Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Page : 592 pages
File Size : 44,7 Mb
Release : 2016-03-25
Category : Computers
ISBN : 9780128042595

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Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology by Hamid R Arabnia,Quoc Nam Tran Pdf

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

An Introduction to Computational Systems Biology

Karthik Raman
An Introduction to Computational Systems Biology Book PDF

Author : Karthik Raman
Publisher : CRC Press
Page : 359 pages
File Size : 50,5 Mb
Release : 2021-05-30
Category : Computers
ISBN : 9780429944529

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An Introduction to Computational Systems Biology by Karthik Raman Pdf

Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling

Systems Biology in Practice

Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach
Systems Biology in Practice Book PDF

Author : Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach
Publisher : John Wiley & Sons
Page : 486 pages
File Size : 50,5 Mb
Release : 2008-07-15
Category : Medical
ISBN : 9783527604883

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Systems Biology in Practice by Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach Pdf

Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered - Which experiments to perform - Where to find information in databases and on the Internet - What kinds of models are appropriate - How to use simulation tools - What can be learned from the comparison of experimental data and modeling results - How to make testable predictions. The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction.

Systems and Synthetic Biology

Vikram Singh,Pawan K. Dhar
Systems and Synthetic Biology Book PDF

Author : Vikram Singh,Pawan K. Dhar
Publisher : Springer
Page : 385 pages
File Size : 44,6 Mb
Release : 2014-12-15
Category : Science
ISBN : 9789401795142

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Systems and Synthetic Biology by Vikram Singh,Pawan K. Dhar Pdf

This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.

Elements of Computational Systems Biology

Huma M. Lodhi,Stephen H. Muggleton
Elements of Computational Systems Biology Book PDF

Author : Huma M. Lodhi,Stephen H. Muggleton
Publisher : John Wiley & Sons
Page : 435 pages
File Size : 40,6 Mb
Release : 2010-03-25
Category : Computers
ISBN : 9780470556740

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Elements of Computational Systems Biology by Huma M. Lodhi,Stephen H. Muggleton Pdf

Groundbreaking, long-ranging research in this emergent field that enables solutions to complex biological problems Computational systems biology is an emerging discipline that is evolving quickly due to recent advances in biology such as genome sequencing, high-throughput technologies, and the recent development of sophisticated computational methodologies. Elements of Computational Systems Biology is a comprehensive reference covering the computational frameworks and techniques needed to help research scientists and professionals in computer science, biology, chemistry, pharmaceutical science, and physics solve complex biological problems. Written by leading experts in the field, this practical resource gives detailed descriptions of core subjects, including biological network modeling, analysis, and inference; presents a measured introduction to foundational topics like genomics; and describes state-of-the-art software tools for systems biology. Offers a coordinated integrated systems view of defining and applying computational and mathematical tools and methods to solving problems in systems biology Chapters provide a multidisciplinary approach and range from analysis, modeling, prediction, reasoning, inference, and exploration of biological systems to the implications of computational systems biology on drug design and medicine Helps reduce the gap between mathematics and biology by presenting chapters on mathematical models of biological systems Establishes solutions in computer science, biology, chemistry, and physics by presenting an in-depth description of computational methodologies for systems biology Elements of Computational Systems Biology is intended for academic/industry researchers and scientists in computer science, biology, mathematics, chemistry, physics, biotechnology, and pharmaceutical science. It is also accessible to undergraduate and graduate students in machine learning, data mining, bioinformatics, computational biology, and systems biology courses.

Systems Biology

Jens Nielsen,Stefan Hohmann
Systems Biology Book PDF

Author : Jens Nielsen,Stefan Hohmann
Publisher : John Wiley & Sons
Page : 435 pages
File Size : 48,9 Mb
Release : 2017-05-30
Category : Computers
ISBN : 9783527335589

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Systems Biology by Jens Nielsen,Stefan Hohmann Pdf

Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.