Conceptual Development Of Industrial Biotechnology For Commercial Production Of Vaccines And Biopharmaceuticals

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Conceptual Development of Industrial Biotechnology for Commercial Production of Vaccines and Biopharmaceuticals

Author : Basanta Kumara Behera
Publisher : Elsevier
Page : 314 pages
File Size : 44,6 Mb
Release : 2023-03-07
Category : Science
ISBN : 9780443187490

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Conceptual Development of Industrial Biotechnology for Commercial Production of Vaccines and Biopharmaceuticals by Basanta Kumara Behera Pdf

Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines provides insights on how to bring sustainability into biologic drug production. The cumulative facts and figures within in the book are helpful to promoters in monitoring value chain transfer process of super quality biologics for better return in profits. In addition, this is a useful reference for students, researchers and scientists in biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries. Conceptual development of biotechnology has taken new avenues with the integration of medical sciences, physical science, and engineering, hence this is a timely source. The current global market for vaccines, especially COVID-19, is tremendous. Bivalent oral polio vaccine, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally and recombinant DNA technology and protein engineering are helpful in the production of quality bio-products. Informs how biotechnology and pharmaceutical industries act as central pillars for the stable production of value-added biological drugs and vaccines from genetically engineered suitable vectors like microbe or cell lines from animals, mammals or plants Highlights various traditional and modern techniques used for improvising the quality of suitable vectors to produce biologic drugs and vaccines under GMP manufacturing facilities Provides updated information on the latest microchip-based bioreactors, disposable bag bioreactors, and animal systems as bioreactors to produce biologic drugs like Smart Biomolecules (next generation therapeutics), Bio-similar drugs, Bio-betters, and antibody-drug conjugates Explains how the closed bioreactors with proper mechanical amendments are used for vaccine production

Sustainability and Life Cycle Assessment in Industrial Biotechnology

Author : Magnus Fröhling,Michael Hiete
Publisher : Springer Nature
Page : 363 pages
File Size : 46,8 Mb
Release : 2020-06-16
Category : Science
ISBN : 9783030470661

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Sustainability and Life Cycle Assessment in Industrial Biotechnology by Magnus Fröhling,Michael Hiete Pdf

This book reviews the assessment of industrial biotechnology products and processes from a sustainable perspective. Industrial Biotechnology is a comparably young field which comes along with high expectations with regard to sustainability issues. These stem from the promise of reducing greenhouse gas emissions and replacing fossil resources in the near or later future and using green technology, i.e. more environmentally friendly technologies. The intended economic, ecological and social benefits, however, need to be proven, resulting in a variety of challenges, both from a methodological and application point of view. In this book, specific assessment and application topics of industrial biotechnology are addressed, highlighting challenges and solutions for both developers and users of assessment methods. In twelve chapters, experts in their particular fields define the scope, characterize industrial biotechnology and show in their contributions the state of the art, challenges and prospects of assessing industrial biotechnology products and processes. The chapter 'Societal and Ethical Aspects of Industrial Biotechnology' of this book is available open access under a CC BY 4.0 license at link.springer.com

Putting Biotechnology to Work

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Bioprocess Engineering
Publisher : National Academies Press
Page : 133 pages
File Size : 41,8 Mb
Release : 1992-02-01
Category : Science
ISBN : 9780309047852

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Putting Biotechnology to Work by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Bioprocess Engineering Pdf

The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.

Continuous Manufacturing for the Modernization of Pharmaceutical Production

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology
Publisher : National Academies Press
Page : 69 pages
File Size : 40,9 Mb
Release : 2019-04-05
Category : Medical
ISBN : 9780309487818

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Continuous Manufacturing for the Modernization of Pharmaceutical Production by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology Pdf

On July 30-31, 2018, the National Academies of Sciences, Engineering, and Medicine held a workshop titled Continuous Manufacturing for the Modernization of Pharmaceutical Production. This workshop discussed the business and regulatory concerns associated with adopting continuous manufacturing techniques to produce biologics such as enzymes, monoclonal antibodies, and vaccines. The participants also discussed specific challenges for integration across the manufacturing system, including upstream and downstream processes, analytical techniques, and drug product development. The workshop addressed these challenges broadly across the biologics domain but focused particularly on drug categories of greatest FDA and industrial interest such as monoclonal antibodies and vaccines. This publication summarizes the presentations and discussions from the workshop.

Basic and Applied Aspects of Biotechnology

Author : Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy
Publisher : Springer
Page : 527 pages
File Size : 44,9 Mb
Release : 2016-10-22
Category : Technology & Engineering
ISBN : 9789811008757

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Basic and Applied Aspects of Biotechnology by Varsha Gupta,Manjistha Sengupta,Jaya Prakash,Baishnab Charan Tripathy Pdf

This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.

Industrial Biotechnology

Author : Wim Soetaert,Erick J. Vandamme
Publisher : John Wiley & Sons
Page : 522 pages
File Size : 42,7 Mb
Release : 2010-03-30
Category : Technology & Engineering
ISBN : 9783527630240

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Industrial Biotechnology by Wim Soetaert,Erick J. Vandamme Pdf

Describing all topics of white biotechnology admitted to the 7th EU Frame Programme and new industrial production processes aiming towards the Kyoto objectives, this comprehensive overview covers the technology, applications, economic potential and implications for society. Directed at readers with a general interest in a specific technology, this is equally suitable as an introductory handbook to a wide range of industries, including chemicals, biotechnology and pharmaceuticals, food and feed, paper and pulp, personal care, energy and agriculture.

Modern Applications of Plant Biotechnology in Pharmaceutical Sciences

Author : Saurabh Bhatia,Kiran Sharma,Randhir Dahiya,Tanmoy Bera
Publisher : Academic Press
Page : 452 pages
File Size : 52,8 Mb
Release : 2015-07-22
Category : Science
ISBN : 9780128024980

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Modern Applications of Plant Biotechnology in Pharmaceutical Sciences by Saurabh Bhatia,Kiran Sharma,Randhir Dahiya,Tanmoy Bera Pdf

Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications. Builds upon the basic concepts of cell and plant tissue culture and recombinant DNA technology to better illustrate the modern and potential applications of plant biotechnology to the pharmaceutical sciences Provides detailed yet practical coverage of complex techniques, such as micropropogation, gene transfer, and biosynthesis Examines critical issues of international importance and offers real-life examples and potential solutions

Mucosal Vaccines

Author : David W. Pascual
Publisher : Academic Press
Page : 941 pages
File Size : 41,5 Mb
Release : 2019-10-19
Category : Medical
ISBN : 9780128119259

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Mucosal Vaccines by David W. Pascual Pdf

Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format. Provides the latest views on mucosal vaccines Applies basic and current principles in the field of mucosal immunology and related scientific fields (e.g., microbiology, infectious diseases, systems biology, medicine, dentistry, veterinary medicine and translational research) to the development of new vaccines Links basic, clinical and practical aspects of mucosal vaccines to different infectious diseases Presents user-friendly organization using attractive illustrations

Microalgal Biotechnology

Author : Eduardo Jacob-Lopes,Leila Queiroz Zepka,Maria Isabel Queiroz
Publisher : BoD – Books on Demand
Page : 226 pages
File Size : 52,6 Mb
Release : 2018-06-27
Category : Medical
ISBN : 9781789233322

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Microalgal Biotechnology by Eduardo Jacob-Lopes,Leila Queiroz Zepka,Maria Isabel Queiroz Pdf

Microalgal Biotechnology presents an authoritative and comprehensive overview of the microalgae-based processes and products. Divided into 10 discreet chapters, the book covers topics on applied technology of microalgae. Microalgal Biotechnology provides an insight into future developments in each field and extensive bibliography. It will be an essential resource for researchers and academic and industry professionals in the microalgae biotechnology field.

Biopharmaceuticals

Author : Ming-Kung Yeh,Yuan-Chuan Chen
Publisher : BoD – Books on Demand
Page : 140 pages
File Size : 52,5 Mb
Release : 2018-09-19
Category : Medical
ISBN : 9781789237184

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Biopharmaceuticals by Ming-Kung Yeh,Yuan-Chuan Chen Pdf

Biopharmaceuticals are derived from biological sources, either live organisms or their active components; nowadays, they are mainly produced by biotechnologies. Biopharmaceuticals are extensively used in the treatment of various diseases such as cardiovascular, metabolic, neurological diseases, cancer, and others for which there are no available therapeutic methods. With the advance of science, biopharmaceuticals have revolutionized the treatment, prevention, and diagnosis of many patients with disabling and life-threatening diseases. Innovative biopharmaceuticals definitely improve the life quality of patients and enhance the effectiveness of the healthcare system. This book encompasses the discovery, production, application, and regulation of biopharmaceuticals to demonstrate their research achievement, prospects, and challenges. We expect the significance of biopharmaceuticals to be revealed and emphasized by this book.

Human Vaccines

Author : Kayvon Modjarrad,Wayne C. Koff
Publisher : Academic Press
Page : 186 pages
File Size : 44,8 Mb
Release : 2016-10-15
Category : Medical
ISBN : 9780128025420

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Human Vaccines by Kayvon Modjarrad,Wayne C. Koff Pdf

Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology. Introduces new topics in vaccine immunology in the context vaccine design and production Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 – 3 decades Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety Provides a broad overview of innovative vaccine technologies, including immunological aspects

Role of Biotechnology in Agriculture

Author : B. N. Prasad
Publisher : Unknown
Page : 256 pages
File Size : 49,8 Mb
Release : 1992
Category : Agricultural biotechnology
ISBN : UCAL:B3877050

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Role of Biotechnology in Agriculture by B. N. Prasad Pdf

In the context of South Asian Association for Regional Cooperation countries.

Process Validation in Manufacturing of Biopharmaceuticals

Author : Gail Sofer
Publisher : CRC Press
Page : 402 pages
File Size : 45,5 Mb
Release : 2000-03-24
Category : Science
ISBN : 9781420001655

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Process Validation in Manufacturing of Biopharmaceuticals by Gail Sofer Pdf

A study of biopharmaceutical process validation. It aims to enable developers and producers to ensure safe products, reduce the risk of adverse reactions in patients, and avoid recalls by outlining sophisticated validation approaches to characterize processes, process intermediates, and final product fully. The text emphasizes cost effectiveness while determining what level of validation is required for different phases of development, license application, and process improvements.

Biopharmaceuticals

Author : Gary Walsh
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 49,6 Mb
Release : 2013-04-29
Category : Medical
ISBN : 9781118687383

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Biopharmaceuticals by Gary Walsh Pdf

The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology. This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.