Contemporary Approaches To Mitigating Antibacterial Drug Resistance

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Contemporary Approaches to Mitigating Antibacterial Drug Resistance

Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal
Contemporary Approaches to Mitigating Antibacterial Drug Resistance Book PDF

Author : Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal
Publisher : IGI Global
Page : 384 pages
File Size : 45,5 Mb
Release : 2024-04-01
Category : Medical
ISBN : 9798369315415

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Contemporary Approaches to Mitigating Antibacterial Drug Resistance by Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal Pdf

In infectious disease management, antibacterial agents have long been viewed as pivotal tools in the relentless battle against microorganisms. However, the escalating threat of antibacterial drug resistance has emerged as a formidable challenge to global health. Contemporary Approaches to Mitigating Antibacterial Drug Resistance delves into the heart of this critical issue, exploring the mechanisms, consequences, and innovative strategies to counteract the surge of resistance, a phenomenon becoming increasingly pervasive and threatening worldwide. Antibacterial drug resistance, a pressing public health concern, transcends geographical boundaries. In regions where antibiotic accessibility and overuse prevail, resistance rates soar, giving rise to the ominous "superbugs." This book unravels the intricacies of drug resistance, examining its impact on infectious disease management, healthcare economics, and societal well-being. The exploration begins with a foundational understanding of antibacterial drug resistance, navigating through the intricate mechanisms that drive its rapid proliferation. Environmental and genetic factors, often overlooked, are dissected for their roles in fostering resistance. The book explores the interplay of antibacterial drugs with micro-biodiversity, shedding light on the indirect repercussions on human and environmental ecosystems. The primary audience, encompassing undergraduate and postgraduate students, medical practitioners, academicians, and researchers, will find in-depth insights into emerging therapeutic targets and recent advances in drug development. The secondary audience, including authorities in antibacterial drug resistance and institutional libraries, will discover a valuable resource addressing the multifaceted dimensions of this global menace.

Emerging Modalities in Mitigation of Antimicrobial Resistance

Nadeem Akhtar,Kumar Siddharth Singh,Prerna,Dinesh Goyal
Emerging Modalities in Mitigation of Antimicrobial Resistance Book PDF

Author : Nadeem Akhtar,Kumar Siddharth Singh,Prerna,Dinesh Goyal
Publisher : Springer Nature
Page : 569 pages
File Size : 42,8 Mb
Release : 2022-01-31
Category : Medical
ISBN : 9783030841263

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Emerging Modalities in Mitigation of Antimicrobial Resistance by Nadeem Akhtar,Kumar Siddharth Singh,Prerna,Dinesh Goyal Pdf

Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

National Academies Of Sciences Engineeri,National Academies of Sciences Engineering and Medicine,Health And Medicine Division,Board On Population Health And Public He,Board on Population Health and Public Health Practice,Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States
Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine Book PDF

Author : National Academies Of Sciences Engineeri,National Academies of Sciences Engineering and Medicine,Health And Medicine Division,Board On Population Health And Public He,Board on Population Health and Public Health Practice,Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States
Publisher : National Academies Press
Page : 128 pages
File Size : 53,8 Mb
Release : 2022-07-20
Category : Medical
ISBN : 0309269458

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Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine by National Academies Of Sciences Engineeri,National Academies of Sciences Engineering and Medicine,Health And Medicine Division,Board On Population Health And Public He,Board on Population Health and Public Health Practice,Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States Pdf

The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Mechanisms of antibiotic resistance

Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang
Mechanisms of antibiotic resistance Book PDF

Author : Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang
Publisher : Frontiers Media SA
Page : 226 pages
File Size : 41,7 Mb
Release : 2015-06-01
Category : Antibiotics
ISBN : 9782889195268

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Mechanisms of antibiotic resistance by Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang Pdf

Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Improving Food Safety Through a One Health Approach

Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Improving Food Safety Through a One Health Approach Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 418 pages
File Size : 40,7 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9780309259361

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Improving Food Safety Through a One Health Approach by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Drug Discovery Targeting Drug-Resistant Bacteria

Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta
Drug Discovery Targeting Drug Resistant Bacteria Book PDF

Author : Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta
Publisher : Academic Press
Page : 434 pages
File Size : 52,8 Mb
Release : 2020-05-15
Category : Medical
ISBN : 9780128184813

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Drug Discovery Targeting Drug-Resistant Bacteria by Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta Pdf

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Antimicrobial Resistance

World Health Organization
Antimicrobial Resistance Book PDF

Author : World Health Organization
Publisher : Unknown
Page : 232 pages
File Size : 43,5 Mb
Release : 2014
Category : Medical
ISBN : 9241564741

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Antimicrobial Resistance by World Health Organization Pdf

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

When Antibiotics Fail

The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada
When Antibiotics Fail Book PDF

Author : The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada
Publisher : Council of Canadian Academies
Page : 268 pages
File Size : 54,5 Mb
Release : 2019-11-12
Category : Medical
ISBN : 9781926522753

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When Antibiotics Fail by The Expert Panel on the Potential Socio-Economic Impacts of Antimicrobial Resistance in Canada Pdf

When Antibiotics Fail examines the current impacts of AMR on our healthcare system, projects the future impact on Canada’s GDP, and looks at how widespread resistance will influence the day-to-day lives of Canadians. The report examines these issues through a One Health lens, recognizing the interconnected nature of AMR, from healthcare settings to the environment to the agriculture sector. It is the most comprehensive report to date on the economic impact of AMR in Canada.

Antimicrobial Resistance in Developing Countries

Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Antimicrobial Resistance in Developing Countries Book PDF

Author : Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Publisher : Springer Science & Business Media
Page : 553 pages
File Size : 46,7 Mb
Release : 2009-10-08
Category : Science
ISBN : 9780387893709

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Antimicrobial Resistance in Developing Countries by Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke Pdf

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Antimicrobial Resistance

Mihai Mares,Swee Hua Erin Lim,Kok-Song Lai,Romeo-Teodor Cristina
Antimicrobial Resistance Book PDF

Author : Mihai Mares,Swee Hua Erin Lim,Kok-Song Lai,Romeo-Teodor Cristina
Publisher : BoD – Books on Demand
Page : 210 pages
File Size : 52,5 Mb
Release : 2021-03-03
Category : Medical
ISBN : 9781839624322

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Antimicrobial Resistance by Mihai Mares,Swee Hua Erin Lim,Kok-Song Lai,Romeo-Teodor Cristina Pdf

Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

Ethics and Drug Resistance: Collective Responsibility for Global Public Health

Euzebiusz Jamrozik,Michael Selgelid
Ethics and Drug Resistance Collective Responsibility for Global Public Health Book PDF

Author : Euzebiusz Jamrozik,Michael Selgelid
Publisher : Springer
Page : 448 pages
File Size : 44,5 Mb
Release : 2021-08-21
Category : Philosophy
ISBN : 303027876X

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Ethics and Drug Resistance: Collective Responsibility for Global Public Health by Euzebiusz Jamrozik,Michael Selgelid Pdf

This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

Frontiers in Combating Antibacterial Resistance: Current Perspectives and Future Horizons

Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal
Frontiers in Combating Antibacterial Resistance Current Perspectives and Future Horizons Book PDF

Author : Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal
Publisher : IGI Global
Page : 442 pages
File Size : 55,6 Mb
Release : 2024-03-25
Category : Medical
ISBN : 9798369341407

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Frontiers in Combating Antibacterial Resistance: Current Perspectives and Future Horizons by Grewal, Ajmer Singh,Dhingra, Ashwani Kumar,Nepali, Kunal,Deswal, Geeta,Srivastav, Arun Lal Pdf

The rise of modern antimicrobial drug resistance has evolved into a pressing global health crisis, challenging the very foundation of our ability to combat infectious diseases. The overuse and accessibility of antibiotics, particularly in emerging nations, have given rise to resilient "superbugs," rendering common medications ineffective. This escalating challenge poses a significant threat to public health and leads to heightened healthcare costs, prolonged patient stays, and increased mortality rates. As communities grapple with the urgent need for a coordinated response, a comprehensive understanding of antimicrobial drug resistance and innovative strategies becomes paramount. Frontiers in Combating Antibacterial Resistance: Current Perspectives and Future Horizons is meticulously crafted for academic scholars, researchers, and healthcare professionals. It addresses this critical issue head-on and serves as a beacon of knowledge and a solution-oriented guide. With a focus on elucidating the mechanisms behind antimicrobial drug resistance and exploring emerging therapeutic targets, the book presents an in-depth analysis of the problem. It spans environmental, genetic, and climatic factors influencing resistance, delving into cutting-edge technologies and sustainable strategies for prevention. By offering a holistic view of the issue and proposing evidence-based solutions, the book is an indispensable resource for those seeking to navigate the complex landscape of antimicrobial drug resistance.

Modern Technology in Healthcare and Medical Education: Blockchain, IoT, AR, and VR

Hiran, Kamal Kant,Doshi, Ruchi,Patel, Mayank
Modern Technology in Healthcare and Medical Education Blockchain IoT AR and VR Book PDF

Author : Hiran, Kamal Kant,Doshi, Ruchi,Patel, Mayank
Publisher : IGI Global
Page : 332 pages
File Size : 44,6 Mb
Release : 2024-04-29
Category : Medical
ISBN : 9798369354957

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Modern Technology in Healthcare and Medical Education: Blockchain, IoT, AR, and VR by Hiran, Kamal Kant,Doshi, Ruchi,Patel, Mayank Pdf

The integration of Augmented Reality (AR) and Virtual Reality (VR) with Artificial Intelligence (AI) has immense potential to have beneficial effects for institutions of healthcare and medical education. However, this integration has become so complex, it presents numerous challenges across various domains. Researchers and practitioners often need help to keep pace with the rapid advancements of technologies and applications. Issues such as privacy, security, scalability, and optimization of AR/VR setups remain critical concerns for healthcare industry professionals and academics alike. There needs to be a comprehensive resource that addresses these challenges, if we expect the field to grow in an effective and responsible manner. Modern Technology in Healthcare and Medical Education: Blockchain, IoT, AR, and VR offers a solution to these challenges. By providing insights from researchers and experts in the field, this book serves as a valuable reference for addressing real-world problems. This book is a must-have resource for doctoral and post-doctoral researchers, undergraduate and postgraduate students, industry professionals, and government agencies working in AR/VR. It provides a roadmap for future research and development in this rapidly evolving field. It covers a wide range of topics, including enhancements in AR/VR, AI integration, task-specific training, and applications in healthcare and education.

Impact of AI and Robotics on the Medical Tourism Industry

Hassan, Viana,Albattat, Ahmad,Basheer, Shakeel
Impact of AI and Robotics on the Medical Tourism Industry Book PDF

Author : Hassan, Viana,Albattat, Ahmad,Basheer, Shakeel
Publisher : IGI Global
Page : 383 pages
File Size : 53,7 Mb
Release : 2024-03-18
Category : Business & Economics
ISBN : 9798369322499

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Impact of AI and Robotics on the Medical Tourism Industry by Hassan, Viana,Albattat, Ahmad,Basheer, Shakeel Pdf

In the ancient world, health seekers traversed vast distances to pursue well-being. Fast forward to the 21st century, and the concept of medical tourism has evolved into a global industry worth billions of dollars. The burgeoning demand for quality healthcare has pushed traditional boundaries, necessitating a more sophisticated and interconnected healthcare ecosystem. Integrating Artificial Intelligence (AI) into medical practices empowers individuals to actively manage their health while providing healthcare practitioners with invaluable insights for tailored patient care. Impact of AI and Robotics on the Medical Tourism Industry delves into the transformative impact of AI and robotics on this dynamic sector. It explores how AI can encourage and assist patients in their health plans while augmenting healthcare practitioners' capabilities to utilize specific patient data to offer unique guidance. It dissects real-world examples, such as Cleveland Clinic Abu Dhabi's integration of robotic surgery, showcasing how these technologies revolutionize traditional medical practices.

The Role of Health Literacy in Major Healthcare Crises

Papalois, Vassilios,Papalois, Kyriaki
The Role of Health Literacy in Major Healthcare Crises Book PDF

Author : Papalois, Vassilios,Papalois, Kyriaki
Publisher : IGI Global
Page : 347 pages
File Size : 41,6 Mb
Release : 2024-02-22
Category : Medical
ISBN : 9781799896548

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The Role of Health Literacy in Major Healthcare Crises by Papalois, Vassilios,Papalois, Kyriaki Pdf

The COVID-19 pandemic clearly shows the vital role of accurate and reliable information in public health. Health literacy addresses not only patient needs but also the needs of the general population, who must not only comply with advice and instructions but also understand the severity of health crises and respond accordingly. A variety of crises imposed on healthcare systems constantly arise ranging from pandemics to natural catastrophes, terrorist attacks, and outbreaks of illnesses. In addition, there are crises within the healthcare systems, such as a lack of resources and an appropriate workforce. Crises in healthcare systems that are not efficiently dealt with may result in inefficiencies and inequalities in health provision. The Role of Health Literacy in Major Healthcare Crises examines the role of health literacy not only in informing the public but also in building a culture of cooperation between the healthcare systems and their users. The book also investigates the role of communication strategies and educational activities of multiple agencies at local, national, and global levels and explores ethical issues associated with healthcare crises and how they are negotiated in health campaigns. Covering key topics such as digital media, health information, and e-health, this premier reference source is ideal for healthcare professionals, nurses, policymakers, researchers, scholars, academicians, practitioners, instructors, and students.