Contrast Agents I

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Medical Imaging Contrast Agents: A Clinical Manual

Author : Sukru Mehmet Erturk,Pablo R. Ros,Tomoaki Ichikawa,Suzan Saylisoy
Publisher : Springer Nature
Page : 303 pages
File Size : 43,6 Mb
Release : 2021-08-24
Category : Medical
ISBN : 9783030792565

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Medical Imaging Contrast Agents: A Clinical Manual by Sukru Mehmet Erturk,Pablo R. Ros,Tomoaki Ichikawa,Suzan Saylisoy Pdf

This volume highlights and broadens our understanding of the correct use and the possible contraindications of contrast agents applied in radiology. Written by experts in the field, it not only focuses on the chemistry, physiochemical properties and pharmacokinetics of both iodinated and gadolinium-containing contrast agents, but also on the relevant safety issues such as frequency of their short- and long-term side effects and ways to avoid them nephrotoxicity risk related to the iodinated contrast agents NSF (nephrogenic systemic fibrosis) accumulation of gadolinium in the brain use of contrast agents in pediatric patients and pregnancy It also includes essential data on the use of contrast agents, such as scanning protocols, in the context of various clinical conditions. This comprehensive manual addresses all professionals involved in radiological imaging and is an invaluable tool for radiologists and technologists, as well as for residents and clinicians.

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

Author : Andre S. Merbach,Lothar Helm,Éva Tóth
Publisher : John Wiley & Sons
Page : 514 pages
File Size : 53,8 Mb
Release : 2013-02-19
Category : Science
ISBN : 9781118503676

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The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by Andre S. Merbach,Lothar Helm,Éva Tóth Pdf

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

Contrast Agents for MRI

Author : Valérie C Pierre,Matthew J Allen
Publisher : Royal Society of Chemistry
Page : 612 pages
File Size : 41,8 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9781788012546

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Contrast Agents for MRI by Valérie C Pierre,Matthew J Allen Pdf

As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.

X-Ray Contrast Media

Author : Ulrich Speck
Publisher : Springer Science & Business Media
Page : 53 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783662027097

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X-Ray Contrast Media by Ulrich Speck Pdf

Short presentation of aspects important for the application of X-ray contrast media: Composition and properties of contrast media, handling with respect to stability, purity and sterility; applications, interaction, risks; drugs for prophylaxis and treatment of side effects.

Contrast Agents I

Author : Werner Krause
Publisher : Springer
Page : 249 pages
File Size : 43,9 Mb
Release : 2003-07-01
Category : Science
ISBN : 9783540457336

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Contrast Agents I by Werner Krause Pdf

Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].

Contrast Media

Author : Henrik S. Thomsen,Judith A. W. Webb
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 45,7 Mb
Release : 2009-02-14
Category : Medical
ISBN : 9783540727842

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Contrast Media by Henrik S. Thomsen,Judith A. W. Webb Pdf

Two years only after the publication of the ? rst edition of “Contrast media – Safety issues and ESUR guidelines” in our book series Medical Radiology in 2006, it appeared that a second edition was urgently needed. The ? rst edition was indeed an exceptional success with our readership and sold out rapidly, but moreover the safety of MR contrast media urgently required a reappraisal after the publication of a new and dramatic adverse reaction to some of the gadolini- based agents: the so called NSF syndrome. I am very much indebted to Professor Henrik S. Thomsen and his academic colleagues from the ESUR Contrast Medium Safety Committee for accepting the task to prepare a second edition of their remarkable book.Within a record short period of time they have been able to complete this fully revised new volume. It offers to the readers a comprehensive overview of all problems related to the use of contrast media in modern radiology and of our latest knowledge and insights in the mechanisms of adverse reactions related to contrast media. It answers all questions that radiologists and referring physicians are confronted with in their daily practice when they consider the administration of these agents to their patients.

Contrast Media in Radiology

Author : M. Amiel
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642685842

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Contrast Media in Radiology by M. Amiel Pdf

Journalists, always very direct and in search of sensation, essentially asked me two questions on the occasion of this workshop: What were the goals of the meeting? With the improvement of diagnosis through the development of image techniques, didn't the contrast media already have their future behind them? Many answers were provided during the course of the workshop, and in order to best answer the journalists I proposed the following synopsis. 1. Since the 1979 Colorado Springs workshop organized by E. Lasser, progress has been so rapid and the newly available works so numerous that another meeting on an international level for the purpose of pre senting and discussing these advances appeared indispensable. Why not then in Europe and why not in Lyon? To expand on this progress, by 1981 the new contrast media with less-hyperosmolar molecules, still in the trial stage in 1979, were al most all available commercially for angiography, albeit at prohibitive prices. The advantages of these various media are becoming better known; moreover, in the wake of Lasser's work, our understanding of the pathophysiology of their noxious effects is also advancing rapidly owing to the use of models (for the target organs: heart, vessel wall, nervous system, kidney; and for the more general reactions: blood cells, coagulation, complement system, circulating enzymatic systems). In addition, further new molecules are currently being studied in re search laboratories. 2.

Contrast Media in Ultrasonography

Author : Emilio Quaia
Publisher : Springer Science & Business Media
Page : 452 pages
File Size : 54,5 Mb
Release : 2005-03-08
Category : Medical
ISBN : 3540407405

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Contrast Media in Ultrasonography by Emilio Quaia Pdf

Examines in detail the different clinical applications of microbubble-based contrast agents. Explains the principles underlying the use of contrast-specific imaging techniques and the examination methodology. Contains numerous high-quality illustrations, including many in color. Written by recognized experts.

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

Author : Andre S. Merbach,Lothar Helm,Éva Tóth
Publisher : John Wiley & Sons
Page : 514 pages
File Size : 50,6 Mb
Release : 2013-04-15
Category : Science
ISBN : 9781119991762

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The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by Andre S. Merbach,Lothar Helm,Éva Tóth Pdf

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 725 pages
File Size : 41,5 Mb
Release : 2015-02-25
Category : Science
ISBN : 9781466565999

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Brain Neurotrauma by Firas H. Kobeissy Pdf

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

X-ray Contrast Agent Technology

Author : Christoph de Haen
Publisher : CRC Press
Page : 326 pages
File Size : 41,7 Mb
Release : 2019-04-08
Category : Science
ISBN : 9780429787232

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X-ray Contrast Agent Technology by Christoph de Haen Pdf

This book documents the fascinating history of radiological techniques that use contrast agents. The text includes many of the fundamental documentary sources that bring to life the social and scientific background of the discoveries, the personalities of the discoverers, and implementation of new technologies. Such agents when used with X-rays allow clinicians to distinguish anatomical structures with nearly identical densities. Focus is on urological and angiographic uses of contrast agents. Key selling features: Documents and thoroughly references the history of contrast agent development Reviews the priority and importance of patents Discusses the role that important individual scientists and leading research institutions have played in technology development and implementation

Acoustic Characterization of Contrast Agents for Medical Ultrasound Imaging

Author : L. Hoff
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 55,7 Mb
Release : 2001-12-31
Category : Medical
ISBN : 1402001444

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Acoustic Characterization of Contrast Agents for Medical Ultrasound Imaging by L. Hoff Pdf

"The book consists of nine chapters. The first 3 chapters give a broad overview of the acoustic theory for bubble-sound interaction, both linear and nonlinear. Most contrast agents are stabilized in a shell, and this shell can have a strong influence on the interaction between the bubbles and the ultrasound. The effect of the shell is given special attention, as this is not easily found in other bubble literature. Chapters 4, 5, 6 and 7 describe experimental and theoretical methods used to characterize the acoustic properties of the agents, and results of studies on some agents. Chapter 8 shows how the theory and the experimental results can be combined and used to model various phenomena by means of computer simulations. The main purpose of the simulations is to get insight into the mechanisms behind the described phenomena, not to get accurate predictions and values.

Multislice CT

Author : M.F. Reiser,M. Takahashi,M. Modic,R. Bruening
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642594410

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Multislice CT by M.F. Reiser,M. Takahashi,M. Modic,R. Bruening Pdf

The introduction of multidetector spiral CT into clinical practice is without any doubt one of the most important technical developments in the field of computed tomography in general, and spiral CT in particular, in recent years. Indeed, multislice CT technology, based on the spiral CT technique invented by W. Kalender almost 20 years ago, has opened immense and totally new perspectives for better utilisation of contrast medium during the examination, for optimal multiplanar reconstruction and for increased patient throughput. The potential applications, more specifically in the area of CT angiography of the brain and the heart and vessels, are most interesting and definitely contribute to better patient care as well as to more effi cient utilisation of equipment. These exciting new clinical applications explain the keen desire of radiologists and other clinicians to hear and learn more about the first results obtained with this new equipment in daily clinical practice. This book will satisfy their needs. Professor Maximilian F. Reiser was among the first to install multidetector CT in his department in Munich and to gain experience with this new radiological tool. He was also able to organise a very successful and well attended international meeting on this hot topic as early as z 2000 in Starnberg, Germany.

Contrast Media

Author : Henrik S. Thomsen,Judith A. W. Webb
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 44,5 Mb
Release : 2009-03-23
Category : Medical
ISBN : 9783540727835

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Contrast Media by Henrik S. Thomsen,Judith A. W. Webb Pdf

This revised edition of Contrast Media: Safety Issues and Guidelines, updates the successful first edition and contains new chapters. It provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.

Trends in Contrast Media

Author : Henrik S. Thomsen,Robert N. Muller,Robert F. Mattrey
Publisher : Springer Science & Business Media
Page : 471 pages
File Size : 41,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642598142

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Trends in Contrast Media by Henrik S. Thomsen,Robert N. Muller,Robert F. Mattrey Pdf

A different approach to contrast media, discussed primarily from the point of view of the radiologist. Comprehensive sections are devoted to iodinated contrast media and to the contrast media employed in magnetic resonance imaging and ultrasonography. The latest agents available receive due attention, as do adverse reactions. A final section considers the use of contrast media in nuclear medicine.