Correspondence On The Discovery And Original Investigations On Kuru
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Correspondence on the Discovery and Original Investigations on Kuru by Joseph Edwin Smadel Pdf
These eighty-two letters speak for themselves. They document the discovery and the origins and pursuance of the first year of study of kuru in great detail and should serve to dispel any misconceptions about who did what, and answer many hows, whens, and whys about the early field work and laboratory investigations on kuru. Above all, the publication of these letters is a tribute to the late Dr. Joseph E. Smadel who had so much to do with the first year of our kuru investigation, and through whom the laboratory at the National Institutes of Health became our base, where we were able to demonstrate the slow virus etiology of kuru, the first proved slow virus infection of man.
Correspondence on the Discovery and Original Investigations on Kuru by Joseph Edwin Smadel Pdf
These eighty-two letters speak for themselves. They document the discovery and the origins and pursuance of the first year of study of kuru in great detail and should serve to dispel any misconceptions about who did what, and answer many hows, whens, and whys about the early field work and laboratory investigations on kuru. Above all, the publication of these letters is a tribute to the late Dr. Joseph E. Smadel who had so much to do with the first year of our kuru investigation, and through whom the laboratory at the National Institutes of Health became our base, where we were able to demonstrate the slow virus etiology of kuru, the first proved slow virus infection of man.
Correspondence on the Discovery and Original Investigations on Kuru by D. Carleton Gajdusek Pdf
Excerpt from Correspondence on the Discovery and Original Investigations on Kuru: Smadel Gajdusek Correspondence, 1955-1958 Dr. John Eccles, Dr; Robert Walsh, Dr. Margaret Holmes, Miss Lois Larkin and the late Dr. Roy T. Simmons in Australia had much to do in providing our first laboratory studies. Dr. John Gunther, Dr. Roy Scragg, Dr. A.v.g. Price and Dr. Terry Abbott of Port Moresby were all instrumental in helping. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Daniel Carleton Gajdusek,Michael P. Alpers,Steven G. Ono
Author : Daniel Carleton Gajdusek,Michael P. Alpers,Steven G. Ono Publisher : Unknown Page : 228 pages File Size : 55,8 Mb Release : 1975 Category : Kuru ISBN : MINN:30000005139930
Bibliography of Kuru by Daniel Carleton Gajdusek,Michael P. Alpers,Steven G. Ono Pdf
Over 1600 entries, generally to literature written between 1957-1974. Covers books, journal articles, and unpublished reports. Includes basic bibliography (arranged by authors) and supplements in related fields, i.e., social and physical anthropology, linguistics, and natural history. Author index.
Charles Darwin's "On the Origins of Species" had two principal goals: to show that species had not been separately created and to show that natural selection had been the main force behind their proliferation and descent from common ancestors. In "Coevolution," the author proposes a powerful new theory of cultural evolution--that is, of the descent with modification of the shared conceptual systems we call "cultures"--that is parallel in many ways to Darwin's theory of organic evolution. The author suggests that a process of cultural selection, or preservation by preference, driven chiefly by choice or imposition depending on the circumstances, has been the main but not exclusive force of cultural change. He shows that this process gives rise to five major patterns or "modes" in which cultural change is at odds with genetic change. Each of the five modes is discussed in some detail and its existence confirmed through one or more case studies chosen for their heuristic value, the robustness of their data, and their broader implications. But "Coevolution" predicts not simply the existence of the five modes of gene-culture relations; it also predicts their relative importance in the ongoing dynamics of cultural change in particular cases. The case studies themselves are lucid and innovative reexaminations of an array of oft-pondered anthropological topics--plural marriage, sickle-cell anemia, basic color terms, adult lactose absorption, incest taboos, headhunting, and cannibalism. In a general case, the author's goal is to demonstrate that an evolutionary analysis of both genes and culture has much to contribute to our understanding of human diversity, particularly behavioral diversity, and thus to the resolution of age-old questions about nature and nurture, genes and culture.
Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded infectious protein agent forms the pathogenesis of the disease. This book presents pathology of the disease along with current knowledge of the structure-activity mechanism in the first two sections. Dyshomeostasis of metals is implicated in the pathogenesis of prions, and this influence is discussed further to understand the prion mechanism. Genetic resistance and immunobiology of the disease are elaborated in the following section. Finally, a computational study on the dynamics of the prion propagation provides a structural basis of the mechanism.
United States. Department of Health, Education, and Welfare
Author : United States. Department of Health, Education, and Welfare Publisher : Unknown Page : 696 pages File Size : 48,5 Mb Release : 1976 Category : Government publications ISBN : MINN:30000005138015
United States. Department of Health, Education, and Welfare. Media and Publication Management Information Staff
Author : United States. Department of Health, Education, and Welfare. Media and Publication Management Information Staff Publisher : Unknown Page : 696 pages File Size : 48,6 Mb Release : 2024-05-12 Category : Electronic ISBN : STANFORD:36105219361248
Publication Catalog of the U.S. Department of Health, Education, and Welfare by United States. Department of Health, Education, and Welfare. Media and Publication Management Information Staff Pdf
