Current Developments In The Detection And Control Of Multi Drug Resistance

Author : Sanket Kaushik
Publisher : Bentham Science Publishers
Page : 181 pages
File Size : 49,8 Mb
Release : 2022-07-26
Category : Medical
ISBN : 9789815049886

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Current Developments in the Detection and Control of Multi Drug Resistance by Sanket Kaushik Pdf

The rise in the incidence of infections is caused by multi drugresistant (MDR) bacteria, it is essential to elucidate the basic mechanism ofantibiotic resistance to discover effective methods for diagnosis and treatmentof infections. The use of pathogen-specific probes offers a faster alternative forpathogen detection and could improve the diagnosis of infection. High resolutionmelting analysis techniques are useful for the detection of multi drugresistant pathogens. Rational Structural Based Drug Design is a common methodto identify a lead compound and take it forward for further developments.This book provides information about recent strategies involved in thediagnosis and treatment of infections caused by MDR bacteria. The volume coversthe use of molecular probes for the quantification of pathogenic bacteria, alongwith other techniques mentioned above. Chapters also cover the use of identificationof novel drug targets from the Lipid A biosynthesis and also from quorum sensingmediated biofilm formation in MDR bacteria. Chapters also cover herbal alternatives for the treatment of MDRbacteria like the use of Cassiaaungustifolia in treatment of various diseases. The reference is suitablefor biomedical students, cellular and molecular biologists.

Author : Sanket Kaushik
Publisher : Bentham Science Publishers
Page : 0 pages
File Size : 54,8 Mb
Release : 2022-07-26
Category : Medical
ISBN : 9815049895

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Current Developments in the Detection and Control of Multi Drug Resistance by Sanket Kaushik Pdf

The rise in the incidence of infections is caused by multi drug resistant (MDR) bacteria, it is essential to elucidate the basic mechanism of antibiotic resistance to discover effective methods for diagnosis and treatment of infections. The use of pathogen-specific probes offers a faster alternative for pathogen detection and could improve the diagnosis of infection. High resolution melting analysis techniques are useful for the detection of multi drug resistant pathogens. Rational Structural Based Drug Design is a common method to identify a lead compound and take it forward for further developments. This book provides information about recent strategies involved in the diagnosis and treatment of infections caused by MDR bacteria. The volume covers the use of molecular probes for the quantification of pathogenic bacteria, along with other techniques mentioned above. Chapters also cover the use of identification of novel drug targets from the Lipid A biosynthesis and also from quorum sensing mediated biofilm formation in MDR bacteria. Chapters also cover herbal alternatives for the treatment of MDR bacteria like the use of Cassia aungustifolia in treatment of various diseases. The reference is suitable for biomedical students, cellular and molecular biologists.

Author : Anonim
Publisher : ScholarlyEditions
Page : 125 pages
File Size : 51,6 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464928574

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Advances in Drug Resistance Research and Application: 2011 Edition by Anonim Pdf

Advances in Drug Resistance Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Drug Resistance. The editors have built Advances in Drug Resistance Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drug Resistance in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Drug Resistance Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Mohmmad Younus Wani,Aijaz Ahmad
Publisher : Academic Press
Page : 270 pages
File Size : 49,7 Mb
Release : 2020-04-30
Category : Business & Economics
ISBN : 9780128205785

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Combination Therapy Against Multidrug Resistance by Mohmmad Younus Wani,Aijaz Ahmad Pdf

Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 333 pages
File Size : 51,6 Mb
Release : 2003-03-26
Category : Medical
ISBN : 9780309168304

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The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Author : R. D. Tyagi,Balasubramanian Sellamuthu,Bhagyashree Tiwari,Song Yan,Patrick Drogui,Xiaolei Zhang,Ashok Pandey
Publisher : Elsevier
Page : 668 pages
File Size : 52,9 Mb
Release : 2020-04-15
Category : Technology & Engineering
ISBN : 9780128197226

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Current Developments in Biotechnology and Bioengineering by R. D. Tyagi,Balasubramanian Sellamuthu,Bhagyashree Tiwari,Song Yan,Patrick Drogui,Xiaolei Zhang,Ashok Pandey Pdf

Current Developments in Biotechnology and Bioengineering: Environmental and Health Impact of Hospital Wastewater narrates the origin (history) of pharmaceuticals discoveries, hospital wastewater and its environmental and health impacts. It covers microbiology of hospital wastewater (pathogens, multi-drug resistance development, microbial evolution and impacts on humans, animals, fish), advanced treatment options (including biological, physical and chemical methods), and highlights aspects required during hospital wastewater treatment processes. This book provides an amalgamation of all recent scientific information on hospital wastewater which is not available in the current literature. Introduces physical, chemical and molecular testing methods for the analysis and characterization of hospital wastewater Discusses the environmental impact and health hazards of hospital wastewater Describes the microbiological aspects of the hospital wastewater, like microbial community, metagenomics, pathogens, VBNC and mechanism of antibiotic resistance development Explains hospital wastewater and its role in microbial evolution Highlights future treatment options, guidelines and drug disposal tactics

Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 53,7 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781119282525

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Antibiotic Drug Resistance by José-Luis Capelo-Martínez,Gilberto Igrejas Pdf

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Page : 2234 pages
File Size : 40,8 Mb
Release : 2001
Category : United States
ISBN : STANFORD:36105050221758

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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2002 by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies Pdf

Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Page : 1826 pages
File Size : 49,5 Mb
Release : 2001
Category : Political Science
ISBN : LOC:00092835455

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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2002: Department of Health and Human Services, Public Health Service by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies Pdf

Author : R. C. Mahajan,Amu Therwath
Publisher : CRC Press
Page : 304 pages
File Size : 54,7 Mb
Release : 2001-12
Category : Electronic
ISBN : 0849309832

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Multi-Drug Resistance in Emerging and Re-Emerging Diseases by R. C. Mahajan,Amu Therwath Pdf

The recent appearance of multi-drug resistant phenotypes has complicated the efforts to completely eradicate diseases such as tuberculosis and malaria, thus underscoring the need for new and innovative scientific approach to the problem. Multi-Drug Resistance in Emerging and Re-Emerging Diseases highlights the state-of-the-art in microbial/parasite control and containment, and discusses ways and means of avoiding development of drug resistance. It explores strategies to combat the nightmare of microbial aggression and resistance and to overcome multiple drug resistance when it emerges in microbial organisms or in cancer cells exposed to chemotherapy. Written by a panel of experts, the book gives you the benefits of both field and clinical experience as well as an in-depth know-how of the pathology of these drug resistant diseases. Topics include malaria, tuberculosis, cholera, leprosy, diarrhoeal diseases, nosocomial diseases, plague, and drug resistance and cancer. Multi-Drug Resistance in Emerging and Re-Emerging Diseases provides a foundation for new initiatives and more collaborative efforts in the fight against resistance to antibiotics by micro-organisms.

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
Publisher : National Academies Press
Page : 219 pages
File Size : 48,9 Mb
Release : 2014-02-28
Category : Medical
ISBN : 9780309285995

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The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS by Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation Pdf

Multidrug-resistant tuberculosis (TB) is caused by bacteria resistant to isoniazid and rifampicin, the two most effective first-line anti-TB drugs, originally developed and introduced in the 1950 and 1960s. Since 2008, the Forum on Drug Discovery, Development, and Translation of the Institute of Medicine has hosted or co-hosted six domestic and international workshops addressing the global crisis of drug-resistant TB, with special attention to the BRICS countries - Brazil, Russia, India, China, and South Africa. The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS is the summary of a workshop convened to address the current status of drug-resistant TB globally and in China. This report considers lessons learned from high burden countries; highlights global challenges to controlling the spread of drug-resistant strains; and discusses innovative strategies to advance and harmonize local and international efforts to prevent and treat drug-resistant TB. Additionally, the report examines the problem of MDR TB and emergent TB strains that are potentially untreatable with drugs available and considers the critical leadership role of the BRICS countries in addressing the threats and opportunities in drug-resistant TB.

Author : Sarfraz Ahmed,Suvash Chandra Ojha,Muhammad Najam-ul-Haq,Muhammad Younus,Muhammad Zaffar Hashmi
Publisher : Springer Nature
Page : 559 pages
File Size : 49,6 Mb
Release : 2021-08-05
Category : Medical
ISBN : 9783030763206

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Biochemistry of Drug Resistance by Sarfraz Ahmed,Suvash Chandra Ojha,Muhammad Najam-ul-Haq,Muhammad Younus,Muhammad Zaffar Hashmi Pdf

This book provides a comprehensive discussion on the current information and evidence on the latest developments in the field of drugs resistance. Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. This leads to negative outcomes at great risk of public health; therefore, increasing efforts are dedicated to the development of a new generation of medications that will help deal with this phenomenon. Decades of technological innovations in drug design have demonstrated the potential of resistance. Enormous information on various aspects of antibiotics resistance is available. However, literature on drug resistance specifically related to infectious and non-infectious diseases is rarely presented, particularly those focusing on the mechanisms, biochemistry, kinetics, dynamics, and management of drug resistance. Therefore, there is an immense need for a systematic compilation on the available information about this issue. All the chapters are logically selected and arranged to provide state-of-the-art information about all aspects of drugs resistance. After an introductory chapter, four chapters are dedicated to infectious microbial diseases, whereas two other chapters are complimenting this theme and focusing on drugs resistance in ear, nose and throat, and skin diseases. The recent advances in the understanding of drugs resistance in lung, neurological, kidney, heart, and liver diseases are also covered. Biochemistry of drugs resistance in cancer, HIV, ocular, reproductive, and diabetes diseases is also discussed. Finally, a chapter dedicated to the “management of drug resistance” has been included.

Author : United States. Congress. House. Committee on Foreign Affairs. Subcommittee on Africa and Global Health
Publisher : Unknown
Page : 64 pages
File Size : 43,7 Mb
Release : 2008
Category : Health & Fitness
ISBN : PSU:000065517949

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Multi-drug Resistant Tuberculosis by United States. Congress. House. Committee on Foreign Affairs. Subcommittee on Africa and Global Health Pdf

Author : Gunjan Arora,Andaleeb Sajid,Vipin Chandra Kalia
Publisher : Springer
Page : 630 pages
File Size : 48,9 Mb
Release : 2017-03-21
Category : Medical
ISBN : 9783319486833

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Drug Resistance in Bacteria, Fungi, Malaria, and Cancer by Gunjan Arora,Andaleeb Sajid,Vipin Chandra Kalia Pdf

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.

Author : Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim
Publisher : Springer
Page : 855 pages
File Size : 46,5 Mb
Release : 2017-06-19
Category : Medical
ISBN : 9783319472669

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Antimicrobial Drug Resistance by Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim Pdf

The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.