Antimicrobial Drug Resistance

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Antimicrobial Drug Resistance

Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim
Antimicrobial Drug Resistance Book PDF

Author : Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim
Publisher : Springer
Page : 773 pages
File Size : 53,9 Mb
Release : 2017-06-19
Category : Medical
ISBN : 9783319467184

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Antimicrobial Drug Resistance by Douglas L. Mayers,Jack D. Sobel,Marc Ouellette,Keith S. Kaye,Dror Marchaim Pdf

The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.

Antibiotic Drug Resistance

José-Luis Capelo-Martínez,Gilberto Igrejas
Antibiotic Drug Resistance Book PDF

Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 45,7 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781119282525

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Antibiotic Drug Resistance by José-Luis Capelo-Martínez,Gilberto Igrejas Pdf

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

One Health and the Politics of Antimicrobial Resistance

Laura H. Kahn
One Health and the Politics of Antimicrobial Resistance Book PDF

Author : Laura H. Kahn
Publisher : JHU Press
Page : 201 pages
File Size : 49,7 Mb
Release : 2016-08-15
Category : Political Science
ISBN : 9781421420059

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One Health and the Politics of Antimicrobial Resistance by Laura H. Kahn Pdf

Does the use of low-dose antibiotics in livestock put human health at risk? Zoonoses—infectious diseases, such as SARS and mad cow, that originate in animals and spread to humans—reveal how intimately animal and human health are linked. Complicating this relationship further, when livestock are given antibiotics to increase growth, it can lead to resistant bacteria. Unfortunately, there are few formal channels for practitioners of human medicine and veterinary medicine to communicate about threats to public health. To address this problem, Dr. Laura H. Kahn and her colleagues are promoting the One Health concept, which seeks to increase communication and collaboration between professionals in human, animal, and environmental health. In One Health and the Politics of Antimicrobial Resistance, Dr. Kahn investigates the use of antibiotics and the surge in antimicrobial resistance in food animals and humans from a One Health perspective. Although the medical community has blamed the problem on agricultural practices, the agricultural community insists that antibiotic resistance is the result of indiscriminate use of antibiotics in human medicine. Dr. Kahn argues that this blame game has fueled the politics of antibiotic resistance and hindered the development of effective policies to address the worsening crisis. Combining painstaking research with unprecedented access to international data, the book analyzes the surprising outcomes of differing policy approaches to antibiotic resistance around the globe. By integrating the perspectives of both medicine and agriculture and exploring the history and science behind the widespread use of growth-promoting antibiotics, One Health and the Politics of Antimicrobial Resistance examines the controversy in a unique way while offering policy recommendations that all sides can accept.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

Institute of Medicine,Board on Global Health,Forum on Emerging Infections
The Resistance Phenomenon in Microbes and Infectious Disease Vectors Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 333 pages
File Size : 43,8 Mb
Release : 2003-03-26
Category : Medical
ISBN : 9780309168304

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The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Antimicrobial Drug Resistance

Douglas Mayers
Antimicrobial Drug Resistance Book PDF

Author : Douglas Mayers
Publisher : Springer Science & Business Media
Page : 692 pages
File Size : 55,6 Mb
Release : 2009-07-14
Category : Medical
ISBN : 9781603275958

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Antimicrobial Drug Resistance by Douglas Mayers Pdf

This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.

Antibiotic Resistance

Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Antibiotic Resistance Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 496 pages
File Size : 55,6 Mb
Release : 2011-01-10
Category : Medical
ISBN : 9780309156110

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Antibiotic Resistance by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Disease Control Priorities, Third Edition (Volume 6)

King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Disease Control Priorities Third Edition Volume 6 Book PDF

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 47,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Improving Food Safety Through a One Health Approach

Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Improving Food Safety Through a One Health Approach Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 418 pages
File Size : 54,6 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9780309259361

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Improving Food Safety Through a One Health Approach by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Antimicrobial Drug Resistance

L Bryan
Antimicrobial Drug Resistance Book PDF

Author : L Bryan
Publisher : Elsevier
Page : 594 pages
File Size : 51,6 Mb
Release : 2012-12-02
Category : Health & Fitness
ISBN : 9780323144957

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Antimicrobial Drug Resistance by L Bryan Pdf

Antimicrobial Drug Resistance presents information regarding the ability of organisms to resist natural and synthetically derived inhibitors. It presents the view of the authors who made significant contributions to the understanding of resistance. The book focuses on inhibitors classified as antifungal, antiviral, and antimalarial, as well as metal ions. It also covers numerous reactions, which have been genetically and biochemically analyzed in this context. Additionally, some chapters cover resistance plasmids of most of the clinically important bacteria. The book is designed to aid those involved in microbiological and pharmaceutical research on antimicrobial agents, clinical infectious diseases and medical microbiology, teaching microbiology and pharmacology, pharmaceutical marketing, and infection control.

Antimicrobial Resistance in Developing Countries

Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Antimicrobial Resistance in Developing Countries Book PDF

Author : Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Publisher : Springer Science & Business Media
Page : 553 pages
File Size : 50,7 Mb
Release : 2009-10-08
Category : Science
ISBN : 9780387893709

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Antimicrobial Resistance in Developing Countries by Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke Pdf

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Superbugs

William Hall
Superbugs Book PDF

Author : William Hall
Publisher : Harvard University Press
Page : 236 pages
File Size : 41,8 Mb
Release : 2018-04-09
Category : Medical
ISBN : 9780674985070

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Superbugs by William Hall Pdf

Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

Drug Discovery Targeting Drug-Resistant Bacteria

Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta
Drug Discovery Targeting Drug Resistant Bacteria Book PDF

Author : Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta
Publisher : Academic Press
Page : 434 pages
File Size : 52,5 Mb
Release : 2020-05-15
Category : Medical
ISBN : 9780128184813

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Drug Discovery Targeting Drug-Resistant Bacteria by Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta Pdf

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Ethics and Drug Resistance: Collective Responsibility for Global Public Health

Euzebiusz Jamrozik,Michael Selgelid
Ethics and Drug Resistance Collective Responsibility for Global Public Health Book PDF

Author : Euzebiusz Jamrozik,Michael Selgelid
Publisher : Springer
Page : 448 pages
File Size : 44,8 Mb
Release : 2021-08-21
Category : Philosophy
ISBN : 303027876X

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Ethics and Drug Resistance: Collective Responsibility for Global Public Health by Euzebiusz Jamrozik,Michael Selgelid Pdf

This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

Antimicrobial Resistance

World Health Organization
Antimicrobial Resistance Book PDF

Author : World Health Organization
Publisher : Unknown
Page : 232 pages
File Size : 50,8 Mb
Release : 2014
Category : Medical
ISBN : 9241564741

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Antimicrobial Resistance by World Health Organization Pdf

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Antimicrobial Resistance in Bacteria from Livestock and Companion Animals

Stefan Schwarz,Lina Maria Cavaco,Jianzhong Shen
Antimicrobial Resistance in Bacteria from Livestock and Companion Animals Book PDF

Author : Stefan Schwarz,Lina Maria Cavaco,Jianzhong Shen
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 45,8 Mb
Release : 2020-07-02
Category : Medical
ISBN : 9781555819804

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Antimicrobial Resistance in Bacteria from Livestock and Companion Animals by Stefan Schwarz,Lina Maria Cavaco,Jianzhong Shen Pdf

The global spread of antimicrobial-resistant pathogenic bacteria is a continuing challenge to the health care of humans and domesticated animals. With no new agents on the horizon, it is imperative to use antimicrobial agents wisely to preserve their future efficacy. Led by Editors Stefan Schwarz, Lina Maria Cavaco, and Jianzhong Shen with Frank Møller Aarestrup, an international team of experts in antimicrobial resistance of livestock and companion animals has created this valuable reference for veterinary students and practitioners as well as researchers and decision makers interested in understanding and preventing antimicrobial resistance.