Cytogenetics And Molecular Cytogenetics

Author : Mahabal Ram
Publisher : PHI Learning Pvt. Ltd.
Page : 676 pages
File Size : 50,5 Mb
Release : 2010-09
Category : Science
ISBN : 9788120340336

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Fundamentals of Cytogenetics and Genetics by Mahabal Ram Pdf

This comprehensive and well-written text provides thorough understanding of the principles and applications of cytogenetics and genetics in an easy-to-understand style. The text is divided into Four parts. Part I on Principles of Cytogenetics deals with evolution and structure of cell, cell division and change, and structure of genetic material. Part II on Principles of Genetics provides detailed discussions on transmission, distribution and arrangement of genetic material, and evolution of species. Part III which is on Molecular Genetics discusses functions of genetic material including biotechnology and genetic engineering, and the last Part IV on Quantitative Genetics deliberates on the course of genetic material in populations. A historical approach to the subject has also been presented to show the continuity and progress. KEY FEATURES: Incorporates latest and up-to-date information on the subjects covered. Provides review questions at the end of each chapter to test the understanding of the concepts discussed. Gives ample references to explore further. Includes a glossary of important terms. The book is eminently suitable for undergraduate and postgraduate students of botany, agriculture, zoology and biotechnology for courses in genetics/genetics and cytogenetics. In addition, the book would also be useful to students appearing in different competitive examinations.

Author : Yao-Shan Fan
Publisher : Humana
Page : 0 pages
File Size : 45,5 Mb
Release : 2010-11-10
Category : Medical
ISBN : 1617373001

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Molecular Cytogenetics by Yao-Shan Fan Pdf

The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DNA probes to metaphase chromosomes or interphase nuclei, have been developed in the past two decades. Many FISH techniques have been implemented for diagnostic services, whereas some others are mainly used for investigational purposes. Several hundreds of FISH probes and hybridization kits are now commercially available, and the list is growing rapidly. FISH has been widely used as a powerful diagnostic tool in many areas of medicine including pediatrics, medical genetics, maternal–fetal medicine, reproductive medicine, pathology, hematology, and oncology. Frequently, a physician may be puzzled by the variety of FISH techniques and wonder what test to order. It is not uncommon that a sample is referred to a laboratory for FISH without indicating a specific test. On the other hand, a cytogeneticist or a technologist in a laboratory needs, from case to case, to determine which procedure to perform and which probe to use for an informative result. To obtain the best results, one must use the right DNA probes and have reliable protocols and measures of quality assurance in place. Also, one must have sufficient knowledge in both traditional and molecular cytogenetics, as well as the particular areas of medicine for which the test is used in order to appropriately interpret the FISH results, and to correlate them with clinical diagnosis, treatment, and prognosis.

Author : Thomas Liehr
Publisher : CRC Press
Page : 422 pages
File Size : 41,6 Mb
Release : 2022-12-07
Category : Science
ISBN : 9781000800401

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Cytogenetics and Molecular Cytogenetics by Thomas Liehr Pdf

Genomic technologies provide the means of diagnosis and management of many human diseases. Without insights from cytogenetics, correct interpretation of modern high-throughput results is difficult, if not impossible. This book summarizes applications of cytogenetics and molecular cytogenetics for students, clinicians and researchers in genetics, genomics and diagnostics. The book combines the state-of-the-art knowledge and practical expertise from leading researchers and clinicians and provides a comprehensive overview of current medical and research applications of many of these technologies. KEY FEATURES • Provides clear summaries of fluorescence in situ hybridization technologies and others • Comprehensively covers established and emerging methods • Chapters from an international team of leading researchers • Useful for students, researchers and clinicians

Author : Usha Dutta
Publisher : Cambridge Scholars Publishing
Page : 265 pages
File Size : 50,5 Mb
Release : 2022-03-22
Category : Science
ISBN : 9781527580657

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Essentials of Cytogenetic and Molecular Cytogenetic Laboratory Testing by Usha Dutta Pdf

This book is a compilation of cytogenetic and molecular cytogenetic techniques that are routinely performed in a molecular cytogenetic laboratory. It provides a summary of chromosomal disorders and mechanisms, along with pictures and details of laboratory procedures. Due to the simplicity of the language used, the principles and techniques discussed here are easily understandable. The book also details modern techniques, which will be of interest for geneticists, academicians, scientists, and clinical geneticists aspiring to establish a molecular cytogenetic lab. It also serves to help geneticists understand each protocol as it is written in a self-explanatory manner for standardizing techniques in their laboratory.

Author : Clayton Fisher
Publisher : Foster Academics
Page : 255 pages
File Size : 43,8 Mb
Release : 2019-06-03
Category : Medical
ISBN : 1632426978

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Advances in Molecular Cytogenetics by Clayton Fisher Pdf

The field of molecular cytogenetics is concerned with the combination of the fields of cytogenetics and molecular biology, to distinguish normal cells from cancer-causing cells. It is a useful tool for the diagnosis and treatment of malignancies of the brain, blood, etc. Novel techniques known as fluorescence in situ hybridization (FISH) are used for molecular cytogenetic studies. These have DNA labeled with uniquely colored fluorescent tags to image specific regions of the genome. Molecular cytogenetic techniques are crucial for the understanding of the structural and functional organization of the nucleus and the chromosome, genome variation, gene expression and evolution. These also give insight into the contribution of genomic variations and chromosomal abnormalities to tumor genetics and medical genetics. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular cytogenetics. It is an upcoming field of science that has undergone rapid development over the past few decades. Students, researchers, experts and all associated with this field will benefit alike from this book.

Author : Yao-Shan Fan
Publisher : Springer Science & Business Media
Page : 409 pages
File Size : 41,9 Mb
Release : 2008-02-05
Category : Medical
ISBN : 9781592593002

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Molecular Cytogenetics by Yao-Shan Fan Pdf

The new techniques of molecular cytogenetics, mainly fluorescence in situ hybridization (FISH) of DNA probes to metaphase chromosomes or interphase nuclei, have been developed in the past two decades. Many FISH techniques have been implemented for diagnostic services, whereas some others are mainly used for investigational purposes. Several hundreds of FISH probes and hybridization kits are now commercially available, and the list is growing rapidly. FISH has been widely used as a powerful diagnostic tool in many areas of medicine including pediatrics, medical genetics, maternal–fetal medicine, reproductive medicine, pathology, hematology, and oncology. Frequently, a physician may be puzzled by the variety of FISH techniques and wonder what test to order. It is not uncommon that a sample is referred to a laboratory for FISH without indicating a specific test. On the other hand, a cytogeneticist or a technologist in a laboratory needs, from case to case, to determine which procedure to perform and which probe to use for an informative result. To obtain the best results, one must use the right DNA probes and have reliable protocols and measures of quality assurance in place. Also, one must have sufficient knowledge in both traditional and molecular cytogenetics, as well as the particular areas of medicine for which the test is used in order to appropriately interpret the FISH results, and to correlate them with clinical diagnosis, treatment, and prognosis.

Author : Barbara Hamkalo
Publisher : Springer Science & Business Media
Page : 354 pages
File Size : 48,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461574798

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Molecular Cytogenetics by Barbara Hamkalo Pdf

This volume represents the Proceedings of the Twenty-Sixth Annual Biology Division Research Conference held April 9-12, 1973 in Gatlinburg, Tennessee. The subject of the symposium was Molecular Cytogenetics and the aim of the meeting was to bring together researchers interested in problems of chromosome organi zation, activity and regulation in prokaryotes and eukaryotes. Cytological, biochemical and genetic approaches to these questions were included since the collective information gained from these disciplines provides an integrated approach to genome structure and function. The meeting was sponsored by the Biology Division of the Oak Ridge National Laboratory*. It would not have been possible with out the interest and cooperation of the organizing committee under the chairmanship of O. L. Miller, Jr. Special thanks are due to the chairmen and speakers for making this volume possible and to Dr. Waldo Cohn for his assistance in editing. Preparation of the completed volume was due in large part to the efforts of Sandra Vaughan of the Biology Division. The Editors Barbara Ann Hamkalo John Papaconstantinou August, 1973 * Operated by the Union Carbide Corporation for the U.S. Atomic Energy Commission.

Author : Marcelo L. Larramendy,Sonia Soloneski
Publisher : BoD – Books on Demand
Page : 170 pages
File Size : 54,6 Mb
Release : 2021-07-14
Category : Medical
ISBN : 9781839689413

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Cytogenetics by Marcelo L. Larramendy,Sonia Soloneski Pdf

This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.

Author : Camila Blair
Publisher : Unknown
Page : 246 pages
File Size : 48,9 Mb
Release : 2019-06-14
Category : Electronic
ISBN : 1632417995

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Molecular Cytogenetics: Methods and Protocols by Camila Blair Pdf

The branch of genetics, which studies how chromosomes relate to cell behavior and their behavior during mitosis and meiosis, is known as cytogenetics. Molecular cytogenetics is a field involving the combination of cytogenetics and molecular biology. It uses several reagents and focuses on identifying and distinguishing normal and cancer-causing cells. It acts as a vital tool for the treatment of malignancies like brain tumors and hematological malignancies. It includes techniques and methods, like fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH). This book is compiled in such a manner, that it will provide in-depth knowledge about the theory and practice of molecular cytogenetics. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included in it. This book aims to equip students and experts with the advanced topics and upcoming concepts in this area.

Author : Sverre Heim,Felix Mitelman
Publisher : John Wiley & Sons
Page : 648 pages
File Size : 47,9 Mb
Release : 2015-06-29
Category : Medical
ISBN : 9781118795514

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Cancer Cytogenetics by Sverre Heim,Felix Mitelman Pdf

The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible

Author : Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services
Publisher : Lulu.com
Page : 104 pages
File Size : 51,6 Mb
Release : 2009
Category : Biology
ISBN : 9780982162217

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Understanding Genetics by Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services Pdf

The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.

Author : J. Sybenga
Publisher : Springer Science & Business Media
Page : 479 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9783642840838

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Cytogenetics in Plant Breeding by J. Sybenga Pdf

An introductory discussion of basic chromosome structure and function preceeds the main text on the application of cytogenetic approaches to the analysis of the manipulation of both the genetic make-up and the genetic transmission system of plant breeding material. Analysis using light and electron microscopy, segregations and molecular techniques, yields information for assessing the material before and after manipulation. Much attention is given to quantitative methods. Manipulation not only involves the construction of specific genotypes, but also chromosomal transmission systems. Although analysis and manipulation in the somatic cycle are considered, the focus is on the generative cycle, with emphasis on analysis and subsequent segregation of specifically constructed material. The book is intended for plant breeders and other scientists interested in the analysis and manipulation of breeding material at the chromosomal level. Comparisons with molecular and cell biological approaches are made, and the potential of the various methods is evaluated.

Author : R. Rieger,A. Michaelis,M.M. Green
Publisher : Springer Science & Business Media
Page : 508 pages
File Size : 48,7 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9783662010129

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A Glossary of Genetics and Cytogenetics by R. Rieger,A. Michaelis,M.M. Green Pdf

The past two decades have witnessed a truly phenomenal growth and expansion in our knowledge of the principles and mechanisms of in heritance. :\iolecular and microbial genetics, for all purposes non-existent at the outset of this period, have developed and flourished to the extent of becoming major branches of genetics from which the most exciting and edifying concepts of gene function and structure have been derived. Similarly, man, heretofore a genetic curiosity, has become in his own right a genetic organism of first rank importance. It is, therefore, not without reason that accompanying the rapid proliferation of genetic knowledge, a parallel increase has occurred in the technical nomen clature and terminology special to the field of genetics and often special to specific branches of genetics. In preparing this glossary of ca. 2500 entries, we have attempted to compile and collate the terminology from seemingly unrelated, widely separated branches of genetics - classical and molecular; microbial and human; cytogenetics and population genetics. We have not been content merely to collect terms and definitions much as is found in a dictionary. Rather our aim has been to provide material suitable and usable both for students and research workers. Accordingly, depending upon our evaluation, some terms have simply been defined, others have been described at some length even to the extent of providing experi mental data.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 47,8 Mb
Release : 1973
Category : Electronic
ISBN : OCLC:320473602

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Molecular Cytogenetics by Anonim Pdf

Author : David M. Green,Stanley K. Sessions
Publisher : Academic Press
Page : 456 pages
File Size : 52,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323140454

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Amphibian Cytogenetics and Evolution by David M. Green,Stanley K. Sessions Pdf

This book appears at a time when molecular cytogenetics is positioned to make a significant impact upon evolutionary studies, enabling problems of chromosomal structure and change to be critically assessed. It is an up-to-date and comprehensive survey of the cytogenetics of a major class of animals, including all three amphibian orders, with chapters authored by international leaders in the field. Amphibian Cytogenetics and Evolution will be of interest to classical and molecular cytogeneticists, systematicists, evolutionary biologists, herpetologists, and anyone using amphibians in genetic research. Offers the only current and comprehensive survey of amphibian cytogenetics Gives authoritative and in-depth coverage of topics of present interest Reviews general cytogenetic topics Presents new insights into evolutionary changes in chromosome structure and amphibian phylogeny and relationships including: Phylogenetic analysis of chromosome data, Current techniques of cytogenetic analysis, Examination of all three amphibian orders