Cytokines And Chemokines In Infectious Diseases Handbook

Author : Malak Kotb,Thierry Calandra
Publisher : Springer Science & Business Media
Page : 425 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781592593095

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Cytokines and Chemokines in Infectious Diseases Handbook by Malak Kotb,Thierry Calandra Pdf

A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Elsevier
Page : 1510 pages
File Size : 43,6 Mb
Release : 2003-04-22
Category : Medical
ISBN : 9780080518794

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The Cytokine Handbook, Two-Volume Set by Angus W. Thomson,Michael T. Lotze Pdf

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features* Covers all main cytokines and chemokines * Written by experts* Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters* Includes major emphasis on clinical applications* Extensively illustrated with tables and figures

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Gulf Professional Publishing
Page : 878 pages
File Size : 51,7 Mb
Release : 2003
Category : Chemokines
ISBN : 0126896631

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The Cytokine Handbook by Angus W. Thomson,Michael T. Lotze Pdf

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Expanded to two volumes, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems.

Author : Angus W. Thomson
Publisher : Unknown
Page : 128 pages
File Size : 52,8 Mb
Release : 2003
Category : Chemokines
ISBN : OCLC:1090039448

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The cytokine handbook. 2 by Angus W. Thomson Pdf

Author : Zlatko Dembic
Publisher : Academic Press
Page : 320 pages
File Size : 42,9 Mb
Release : 2015-05-23
Category : Medical
ISBN : 9780124200104

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The Cytokines of the Immune System by Zlatko Dembic Pdf

The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

Author : George E. Griffin
Publisher : Unknown
Page : 154 pages
File Size : 46,6 Mb
Release : 1994
Category : Communicable diseases
ISBN : 0702018406

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Cytokines in Infection by George E. Griffin Pdf

Author : Thomas Martin
Publisher : CRC Press
Page : 0 pages
File Size : 45,9 Mb
Release : 2000-01-18
Category : Medical
ISBN : 082471931X

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Cytokines in Pulmonary Disease by Thomas Martin Pdf

Focusing on the role of the cytokine network in promoting immunity, this superb interdisciplinary collection intensively investigates the behavior of inflammatory mediators in the pathogenesis and resolution of pathogen-specific pulmonary infections-highlighting recent basic findings and discussing the latest results of clinical trials. Defines the vital role that cytokines play in host defense and the pathophysiology of infections associated with pulmonary disease, emphasizing the potential of immunomodulators and gene therapy in treatment. Cytokines in Pulmonary Disease provides state-of-the-art knowledge of the field of cytokines and pulmonary diseases in a single, authoritative source reviews the roles of cytokines in pathogen-specific infections, including tuberculosis, HIV-related infections, fungal pneumonias, cystic fibrosis, and other disorders assesses the rationale and efficacy of new approaches in both the prevention and treatment of pulmonary infectious disease examines the clinical applications and impact of cytokines in pulmonary disease and more. Written by leading international authorities in their respective fields, Cytokines in Pulmonary Disease will find a place on the bookshelves of specialists in pulmonary and critical care medicine, infectious diseases, surgery, immunology, microbiology, cell and molecular biology, and medical school and graduate students in these disciplines.

Author : Richard A. Kaslow,Janet McNicholl,Adrian V. S. Hill
Publisher : Oxford University Press
Page : 464 pages
File Size : 52,7 Mb
Release : 2008
Category : Language Arts & Disciplines
ISBN : 9780195174908

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Genetic Susceptibility to Infectious Diseases by Richard A. Kaslow,Janet McNicholl,Adrian V. S. Hill Pdf

Infectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. This text uniquely focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1, and deals systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. Section 3 provides a meaningful picture of how these genes operate in infectious disease.

Author : Lionel Mandell,Mark Woodhead,Santiago Ewig,Antoni Torres
Publisher : CRC Press
Page : 849 pages
File Size : 55,9 Mb
Release : 2006-10-27
Category : Medical
ISBN : 9780340816943

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Respiratory Infections by Lionel Mandell,Mark Woodhead,Santiago Ewig,Antoni Torres Pdf

The aim of the volume is to provide an authoritative and international treatise bringing together current knowledge in the field of respiratory infection. The book will be organised by presentation rather than causative organism, a differentiating feature from the existing competition, and will be divided into four parts - 'General Issues', 'Community-acquired Infections', 'Nosocomial Infections' and 'Respiratory Infection in Immunocompromised Patients'. Each chapter will conclude with a summary highlighting practical 'take-home' messages regarding patient management for the reader. It will be highly illustrated, including colour plates where appropriate. The principal market will be pulmonologists with a specialist interest in this area and infectious disease specialists, but that the text will also be of interest to clinical researchers and a useful library reference.

Author : Vassil St. Georgiev
Publisher : Springer Science & Business Media
Page : 545 pages
File Size : 40,9 Mb
Release : 2003-02-27
Category : Medical
ISBN : 9781592592968

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Opportunistic Infections by Vassil St. Georgiev Pdf

The major goal of Opportunistic Infections: Treatment and Prophylaxis is to guide cli- cians who provide care for patients suffering from an underlying immunodeficiency that may significantly weaken their immune defenses and will complicate the effective treatment of opportunistic infections. In spite of a wealth of isolated data, no single text exists in which all the essential information about various infectious opportunistic infections. Although I make no claim to completeness, it is my hope that the present book will fulfill that need. To achieve this goal, I have endeavored to integrate both results from large-scale clinical trials and trials involving small numbers of patients, as well as reports of single cases—mindful that such an approach has its limitations. Opportunistic Infections: Treatment and Prophylaxis is organized into four major parts: bacterial, viral, parasitic, and fungal diseases affecting the immunocompromised population. Each part surveys individual infections caused not only by well-known etiologic agents, but also by new and emerging species often taxonomically closely related to a major disea- producing microorganism and until recently not considered to be human pathogens (Candida spp. and nontuberculous mycobacteria, for example). For the sake of uniformity, within each part, the species have been arranged according to their taxonomic characteristics.

Author : Stefan H. E. Kaufmann,Paul van Helden,Eric Rubin,Warwick J. Britton
Publisher : Wiley-Blackwell
Page : 1350 pages
File Size : 40,6 Mb
Release : 2008-03-17
Category : Science
ISBN : 3527316833

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Handbook of Tuberculosis by Stefan H. E. Kaufmann,Paul van Helden,Eric Rubin,Warwick J. Britton Pdf

Coinciding with the first TB therapies to enter clinical trials in 60 years, this is the most comprehensive account of the latest developments in clinical, therapeutic and basic research into the disease, presented by the most prolific of all researchers in the field. Divided into three clearly structured volumes, the first deals with molecular biology and biochemistry of the pathogen, including genetics and genomics, as well as drug design. The second volume covers cell biology, immunology and vaccine development, while the third is devoted to epidemiology and clinical approaches, including drug resistance, veterinary aspects and clinical field trials. With one new infection worldwide every second, this is an essential reference for bacteriologists, immunologists, pathologists and pathophysiologists, molecular and cell biologists, as well as those working in the pharmaceutical industry.

Author : Jerome Goddard
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 52,8 Mb
Release : 2009-01-06
Category : Medical
ISBN : 9781603274005

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Infectious Diseases and Arthropods by Jerome Goddard Pdf

In this second edition of Infectious Diseases and Arthropods, Jerome Goddard summarizes the latest thinking about the biological, entomological, and clinical aspects of the major vector-borne diseases around the world. His book covers mosquito-, tick-, and flea-borne diseases, and a variety of other miscellaneous vector-borne diseases, including Chagas' disease, African sleeping sickness, onchocerciasis, scrub typhus, and louse-borne infections. The author provides for each disease a description of the vector involved, notes on its biology and ecology, distribution maps, and general clinical guidelines for treatment and control. Among the diseases fully discussed are malaria, dengue and yellow fevers, lymphatic filariasis, spotted fevers, ehrlichiosis, lyme disease, tularemia, and plague. Other arthropod-caused or related problems-such as myiasis, imaginary insect or mite infestations, and arthropod stings and bites-are also treated. At a time when vector-borne diseases are spreading ever more widely, Infectious Diseases and Arthropods provides physicians, infectious disease specialists, medical entomologists, and public health officials with an up-to-date, readily accessible, gold-standard reference source.

Author : Stephen C. Piscitelli,Keith Rodvold
Publisher : Springer Science & Business Media
Page : 534 pages
File Size : 49,7 Mb
Release : 2007-10-28
Category : Medical
ISBN : 9781592599240

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Drug Interactions in Infectious Diseases by Stephen C. Piscitelli,Keith Rodvold Pdf

Over the past 25 years, the world’s population has witnessed an explosion in kno- edge about infectious diseases. The global population is coming to the realization that diseases long recognized to cause substantial suffering, such as malaria, tuberculosis, schistosomiasis, and hepatitis, can be diagnosed and treated, and that transmission can be prevented using tools that are available, and which may be becoming increasingly affordable. The global population is recognizing that few infections are local: the travel of humans, other animals, insects, and food transport pathogens around the world, often with astonishing rapidity. New pathogens are appearing, either newly recognized or newly developing, such as severe acute respiratory syndrome (SARS), avian inf- enza, metapneumovirus, or hepatitis C, which are causing human morbidity and m- tality. Finally, there is growing fear that dangerous pathogens may be intentionally introduced into human populations by deranged individuals or terrorist organizations. The potential to use drugs or biologic agents to treat and prevent infectious diseases has increased dramatically over the past quarter century as we have learned more about the biology of many of these agents, and as we have developed techniques to discover new agents by high throughput screening programs and by sophisticated drug design and synthesis.

Author : Michael J. Parnham,Frans P. Nijkamp,Adriano G. Rossi
Publisher : Springer Nature
Page : 888 pages
File Size : 49,5 Mb
Release : 2019-12-10
Category : Medical
ISBN : 9783030108113

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Nijkamp and Parnham's Principles of Immunopharmacology by Michael J. Parnham,Frans P. Nijkamp,Adriano G. Rossi Pdf

Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Author : Shabbir Simjee
Publisher : Springer Science & Business Media
Page : 545 pages
File Size : 42,6 Mb
Release : 2007-11-13
Category : Medical
ISBN : 9781597455015

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Foodborne Diseases by Shabbir Simjee Pdf

In this book, leading authorities present a broad overview of the microbial pathogens and toxins associated with foodborne illness while discussing pathogenicity, clinical epidemiology, diagnosis, and treatment. The volume covers all the bacterial pathogens, viruses, protozoans, and parasites, as well as microbial toxins. Additionally, authors discuss pathogen control strategies and look toward future innovations in food safety technology.