The Cytokine Handbook

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Elsevier
Page : 1572 pages
File Size : 48,5 Mb
Release : 2003-04-22
Category : Medical
ISBN : 0080518796

Get Book

The Cytokine Handbook, Two-Volume Set by Angus W. Thomson,Michael T. Lotze Pdf

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Gulf Professional Publishing
Page : 878 pages
File Size : 50,5 Mb
Release : 2003
Category : Chemokines
ISBN : 0126896631

Get Book

The Cytokine Handbook by Angus W. Thomson,Michael T. Lotze Pdf

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Expanded to two volumes, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems.

Author : Angus W. Thomson
Publisher : Unknown
Page : 128 pages
File Size : 51,8 Mb
Release : 2003
Category : Chemokines
ISBN : OCLC:1090039448

Get Book

The cytokine handbook. 2 by Angus W. Thomson Pdf

Author : Zlatko Dembic
Publisher : Academic Press
Page : 320 pages
File Size : 48,9 Mb
Release : 2015-05-23
Category : Medical
ISBN : 9780124200104

Get Book

The Cytokines of the Immune System by Zlatko Dembic Pdf

The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

Author : Malak Kotb,Thierry Calandra
Publisher : Springer Science & Business Media
Page : 425 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781592593095

Get Book

Cytokines and Chemokines in Infectious Diseases Handbook by Malak Kotb,Thierry Calandra Pdf

A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.

Author : Takayuki Yoshimoto,Tomohiro Yoshimoto
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 53,6 Mb
Release : 2013-10-28
Category : Medical
ISBN : 9784431544425

Get Book

Cytokine Frontiers by Takayuki Yoshimoto,Tomohiro Yoshimoto Pdf

This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics. Different cytokines stimulate diverse responses in various phases of inflammation and immunity, including the innate immune response, the generation of effector T cells, and the development of antibodies by the humoral immune system. It is now clear that the pathophysiology of many infectious, autoimmune, allergic, and malignant diseases can be largely explained by which cytokines are induced and subsequently regulate the cellular responses. In clinical medicine, cytokines are involved in a wide spectrum of diseases. This book describes in three parts the properties and roles of 15 key cytokines under physiological and pathological conditions. Part I presents nine cytokines associated with inflammatory disorders, pro-inflammatory cytokines, and the recently identified new helper T (Th) subset: Th17 cells. Part II gives details of three cytokines associated with allergic disorders, including Th2 responses and recently identified types of innate cells. Part III describes three cytokines that are associated with immunological tolerance and anti-inflammation, including regulatory T (Treg) cells, IL-10-producing Treg (Tr1) cells, and inducible IL-35-producing Treg (iTr35) cells. Cytokines are considered to be important as therapeutic targets for specific agonists or antagonists in numerous immune and inflammatory diseases. The ultimate goal of this book is to facilitate the development of therapeutic treatments for such diseases which has been limited by an insufficient understanding of the biology of cytokines and the complicated network that they create.

Author : Bharat B. Aggarwal,Jordan U. Gutterman
Publisher : Unknown
Page : 128 pages
File Size : 50,9 Mb
Release : 1992
Category : Cytokines
ISBN : 0865421838

Get Book

Human Cytokines by Bharat B. Aggarwal,Jordan U. Gutterman Pdf

Author : Anthony R. Mire-Sluis,Robin Thorpe
Publisher : Academic Press
Page : 584 pages
File Size : 47,5 Mb
Release : 1998-04-15
Category : Medical
ISBN : 0080530214

Get Book

Cytokines by Anthony R. Mire-Sluis,Robin Thorpe Pdf

This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book. Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information. Genetic information and sequences Protein structure Cell sources and production Biological activity Cytokine receptor structure and signal transduction Discussion of the role of cytokines in disease and the potential for therapy Summary table of essential facts Comprehensive bibliography

Author : Randy Q. Cron,Edward M. Behrens
Publisher : Springer Nature
Page : 607 pages
File Size : 52,8 Mb
Release : 2019-09-09
Category : Medical
ISBN : 9783030220945

Get Book

Cytokine Storm Syndrome by Randy Q. Cron,Edward M. Behrens Pdf

Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.

Author : Robin E. Callard,A. J. H. Gearing
Publisher : Unknown
Page : 292 pages
File Size : 43,5 Mb
Release : 1994
Category : Cytokines
ISBN : 0121551431

Get Book

The Cytokine Factsbook by Robin E. Callard,A. J. H. Gearing Pdf

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for. More than 45 entries on human and murine cytokines and their receptors, including: * Cytokine receptor superfamilies * Interleukins 1-15 * Other cytokines * Additional information is provided on: * Alternative nomenclature * Cross reactivity * Sources * Bio assays * Physicochemical properties of the cytokines and their receptors * 3-D structure * Gene structure and chromosomal localisation * Amino acid sequences of the cytokines and their receptors * Receptors * Receptor distribution * Signal transduction * Chromosomal location of the receptors * References

Author : Anthony R. Mire-Sluis,Robin Thorpe
Publisher : Academic Press
Page : 616 pages
File Size : 52,8 Mb
Release : 1998-05-26
Category : Medical
ISBN : UOM:39015041791636

Get Book

Cytokines by Anthony R. Mire-Sluis,Robin Thorpe Pdf

This book provides comprehensive coverage of the cytokines. The chapters are presented in a consistent format allowing easy cross-reference; each chapter has sections on biological activity, receptor details including structure and signal transduction, as well as disease and therapy information. Summary tables and extensive references are also included.

Author : Bharat B. Aggarwal
Publisher : Wiley-Blackwell
Page : 544 pages
File Size : 49,8 Mb
Release : 1996-06-13
Category : Science
ISBN : 0865424411

Get Book

Human Cytokines by Bharat B. Aggarwal Pdf

Human Cytokines II will review the new generation of molecules and their place in the diagnosis and treatment of cancer and viral, infectious, and immunologic diseases, et al. It includes the new interleukens, new transforming growth factor, and exciting recent information on stem cell factor and inhibitors. The field remains one of the hottest areas of cancer research, with new cytokines and new clinical successes constantly reported. The uses for these proteins show signs of only expanding, as the identification and application process is refined. I expect that we will shortly be discussing the possibility of a Cytokines III

Author : Charles N. Serhan,Peter A. Ward,Derek W. Gilroy
Publisher : Cambridge University Press
Page : 489 pages
File Size : 55,8 Mb
Release : 2010-04-26
Category : Medical
ISBN : 9780521887298

Get Book

Fundamentals of Inflammation by Charles N. Serhan,Peter A. Ward,Derek W. Gilroy Pdf

The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion.

Author : Bharat B. Aggarwal,Jordan U. Gutterman
Publisher : Unknown
Page : 128 pages
File Size : 53,6 Mb
Release : 1998
Category : Cytokines
ISBN : 0865421838

Get Book

Human Cytokines by Bharat B. Aggarwal,Jordan U. Gutterman Pdf

Author : Richard Bucala
Publisher : World Scientific
Page : 399 pages
File Size : 54,9 Mb
Release : 2012
Category : Medical
ISBN : 9789814335355

Get Book

The MIF Handbook by Richard Bucala Pdf

The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.