Deep Brain Stimulation In Neurological And Psychiatric Disorders
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Deep Brain Stimulation in Neurological and Psychiatric Disorders by Daniel Tarsy,Jerrold Lee Vitek,Philip Starr,Michael Okun Pdf
This important book discusses today’s most current and cutting-edge applications of Deep Brain Stimulation (DBS). The book begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections which underlie the application of DBS to neurological and psychiatric disorders. This is followed by proposed mechanisms of action of DBS based on functional neuroimaging and neurophysiologic studies in animals and man.
The development of deep brain stimulation for neurological and psychiatric disorders: clinical, societal and ethical issues by Thomas E. Schlaepfer,Chiara Saviane Pdf
To date more than eighty thousand patients worldwide have received deep brain stimulation (DBS), mainly in order to alleviate symptoms of treatment-resistant disorders such as tremor associated with Parkinson’s disease, essential tremor, chronic pain, epilepsy, obsessive compulsive disorder, major depression and Tourette syndrome. The number of indications for neurological and psychiatric conditions using this technology is rapidly increasing, raising important societal and ethical issues that cannot be dealt with by scientists and clinicians on their own, but need discussions among all possible stakeholders on questions such as: what are the comprehensive risks and benefits of this technology? what is the real impact on patients’ life, in terms of health, quality of life and personal identity? This Research Topic provides an overview of potentials and limitations of deep brain stimulation as used to treat neurological and psychiatric conditions, bringing together Mini Reviews, Perspectives and Opinion papers from key stakeholders interested in the development and social impact of this technology. It is also a continuation of the debate that started among scientists, clinicians, patients, sociologists, journalists, philosophers and other experts during the “brains in dialogue on deep brain stimulation” workshop that was organized in September 2010 in Warsaw, Poland, by the FP7 project bid – brains in dialogue (www.neuromedia.eu) coordinated by the Interdisciplinary Laboratory of SISSA (Trieste, Italy).
Deep Brain Stimulation for Neurological Disorders by Toru Itakura Pdf
Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world.
Fundamentals and Clinics of Deep Brain Stimulation by Yasin Temel,Albert F.G. Leentjens,Rob M.A. de Bie,Stephan Chabardes,Alfonso Fasano Pdf
This book provides a state-of-the-art overview of our current understanding of deep brain stimulation (DBS) for the treatment of neurological and psychiatric disorders. With a broad multidisciplinary scope, it presents contributions from leading experts in the field from Europe and America, who share not only their knowledge, but their experience as well. The book focuses both on basic and theoretical aspects of DBS, as well as clinical and practical aspects. It follows an evidence-based approach, and where possible offers clinical recommendations based on published guidelines. It starts with a general section, which discusses basic principles and general considerations. This is followed a sections dedicated to neurological disorders, and psychiatric disorders, in which only accepted indications are discussed. All experimental indications are discussed in the final chapter. The text is supplemented with numerous illustrations. Intended for medical specialists and residents involved in the treatment of patients with DBS, it also appeals to other professionals working with DBS patients, such as psychologists, nurses, physiotherapists, as well as basic and clinical neuroscientists.
Non-invasive Brain Stimulation in Neurology and Psychiatry by Ignacio Obeso,Antonio Oliviero,Marjan Jahanshahi Pdf
The potential efficacy of non-invasive brain stimulation procedures for the management of specific symptoms in diverse neurological and psychiatric conditions has been tested in the past decade or so. For example, repetitive transcranial magnetic stimulation (rTMS) over prefrontal areas has been extensively investigated as a treatment for patients with medication-resistant depression and has been shown to be associated with improvement of mood. Similarly, non-invasive stimulation techniques have been applied to various symptoms of Parkinson's disease such as bradykinesia and dyskinesias, with variables degrees of success reported. However, attempts to expand previously observed clinical improvements to other neurological disorders (e.g. Tourette's syndrome, autism, epilepsy) has been controversial. In trying to bypass potential confounding elements, researchers aim to target neural populations altered in disease to either increase or decrease their corrupted baseline activity. In addition, a complementary approach is to extend stimulation protocols that results enhanced behavior in healthy participants. This Frontiers Research Topic on non-invasive brain stimulation and enhancement of function tries to combine a series of articles from researchers who used non-invasive brain stimulation to aim improvement of either a motoric, cognitive or behavioral nature investigated behaviorally, physiologically or using brain imaging techniques in clinical populations. Investigation of the relation between enhancement of function in healthy populations and clinical improvement in patients with neurological or psychiatric disorders needs further consideration.
Deep Brain Stimulation by Damiaan Denys,Matthijs Feenstra,Rick Schuurman Pdf
This book examines present developments and the future possibilities of deep brain stimulation therapy for patients with therapy-refractory psychiatric disorders. Presents clinical applications and animal research, and offers a chapter on ethical issues.
Author : William J. Marks,Jill L. Ostrem Publisher : Cambridge University Press Page : 295 pages File Size : 52,6 Mb Release : 2022-06-30 Category : Medical ISBN : 9781108864176
Deep Brain Stimulation Management by William J. Marks,Jill L. Ostrem Pdf
Deep brain stimulation (DBS) is now a firmly established treatment for movement disorders, and an increasing body of evidence supports DBS in the treatment of other neurological and psychiatric disorders. This essential reference guide outlines a practical approach to the use of this paradigm-shifting therapy and covers key aspects of DBS practice. Chapters describe how to implement a DBS program and select appropriate patients, device programming to achieve optimal symptom control, and long-term management of patients. Thoroughly revised, this third edition includes additional chapters on managing patients with emerging applications of DBS. An entire chapter is dedicated to troubleshooting common problems with the therapy as many 'failures' are preventable and addressable. With contributions from experts in the field, this is a must-have reference guide for any clinician working with DBS patients.
Arousal in Neurological and Psychiatric Diseases by Edgar Garcia-Rill Pdf
Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism
The Clinical and Ethical Practice of Neuromodulation – Deep Brain Stimulation and Beyond by Markus Christen,Sabine Müller Pdf
Neuromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
Deep Brain Stimulation by Kelvin L. Chou,Susan Grube,Parag G. Patil Pdf
A deep brain stimulator (DBS) device is like a pacemaker for the heart, but the electrodes are placed into the brain. DBS helps in neurological disorders by changing the activity of brain cells depending on where the electrodes are placed. In 1973, Yoshio Hosobuchi first performed chronic deep brain stimulation, to treat pain, by implanting electrodes. In 2002, long - term results of pallidal stimulation were reported for Parkinson's disease. Thus, this book discusses how Parkinson's disease, essential tremor, dystonia, and a few other neurological and psychiatric disorders are treated with DBS
Deep Brain Stimulation Programming by Erwin B Montgomery, Jr Pdf
Deep brain stimulation programming (DBS) continues to grow as an effective therapy for a wide range of neurological and psychiatric disorders, helping patients reach optimal control of their disorder. With the technique finding so much success, the next question is how to make the complexities of post-operative programming cost-effective, especially when traditional medications and treatments can no longer do the job. The second edition of Deep Brain Stimulation Programming is fully revised and up-to-date with the latest technologies and focuses on post-operative programing, which no other text does. This book provides programmers with a foundation of the brain as an electrical device, focusing on the mechanisms by which neurons respond to electrical stimulation, how to control the stimulation and the regional anatomy, and the many variations that influence a patient's response to DBS. Dr. Montgomery explores new techniques of programming; including those based on stimulation frequency, closed-loop DBS, and the roles of oscillators in DBS; and new technological advances that make pre-existing theories of pathophysiology obsolete. Key Features of the Second Edition Include · Highlights post-operative deep brain stimulation; · Includes the most recent discoveries in deep brain stimulation programming; · Highly illustrated with figures for absorption of key programming and techniques; · Provides an appendix of additional resources available through the Greenville Neuromodulation Center.
Deep Brain Stimulation for Parkinson's Disease by Gordon H. Baltuch,Matthew B. Stern Pdf
Considered the largest breakthrough in the treatment of Parkinson's disease in the past 40 years, Deep Brain Stimulation (DBS) is a pioneering procedure of neurology and functional neurosurgery, forging enormous change and growth within the field. The first comprehensive text devoted to this surgical therapy, Deep Brain Stimulation for Parkinson's
Deep brain stimulation (DBS) as a therapy in neurological and psychiatric disorders is applied widely. In this respect, DBS in animal models is performed to study the underlying mechanisms and to evaluate new indications and technology. This chapter summarizes our experience with DBS in animal models, and relevant literature. Electrodes for DBS in animal models have been developed using translational principles, to allow DBS under anesthesia and in freely moving conditions. The stimulation parameters have been adjusted for the animals using current density calculations. This paradigm of experimental DBS has been validated in a variety of animal models of neurological and psychiatric disorders. During the process of development and validation of DBS in animal models, specific problems have been encountered, which are discussed in the chapter. DBS in animal models is an adequate paradigm to explore the underlying mechanisms and new indications for DBS, and to refine DBS technology.