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Author : World Health Organization Publisher : World Health Organization Page : 159 pages File Size : 40,5 Mb Release : 2009 Category : Medical ISBN : 9789241547871
This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.
Dengue and Dengue Hemorrhagic Fever, 2nd Edition by Duane J. Gubler,Eng Eong Ooi,Subhash Vasudevan,Jeremy Farrar Pdf
Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. Recent exciting research on dengue has resulted in major advances in our understanding of all aspects of the biology of these viruses, and this updated second edition brings together leading research and clinical scientists to review dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management.
New Treatment Strategies for Dengue and Other Flaviviral Diseases by Gregory R. Bock,Jamie A. Goode Pdf
Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of dengue virus, of which DENV-2 has been the most prevalent in many recent epidemics. Following primary infection, lifelong immunity develops, preventing repeated assault by the same serotype. However, the non-neutralizing antibodies from a previous infection or maternally acquired antibodies are thought to form complexes with a different serotype during a subsequent infection and cause dengue haemorrhagic fever/dengue shock syndrome, which can be fatal. There is no treatment or vaccine available today that can combat this emerging and uncontrolled disease. This book features contributions from the world’s leading researchers working on dengue and related flaviviruses who examine the current state of the art in the molecular biology of the dengue virus. Particular emphasis is placed on the structure and function of the virus and the targeting of virus proteins by potential antiviral agents. The pathogenesis of dengue and dengue haemorrhagic fever are discussed in detail, especially the target cells and the specific receptors on these cells, thereby developing a clear overview of host and viral factors that contribute to dengue haemorrhagic fever. Finally, the book reviews the therapeutic options, paying particular attention to ways in which vector, host and environment can play a critical role in the spread of this disease. With dengue fever and other emerging viral diseases becoming increasingly prevalent around the world, this book provides valuable insight into the virus that causes this disease and potential ways to manage it. It is essential reading for all those working in tropical diseases, public health and virology. Praise from the reviews: "The book provides an excellent summary of dengue/flavivirus research and is important for individuals and institutions interested in emerging infectious diseases." MICROBIOLOGY TODAY
CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Pdf
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Author : WHO Regional Office for South-East Asia Publisher : World Health Organization Page : 0 pages File Size : 54,6 Mb Release : 2011 Category : Medical ISBN : 9290223944
Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever by WHO Regional Office for South-East Asia Pdf
Dengue Fever is the fastest emerging arboviral infection with major public health consequences for millions of people around the world, and in particular the South-East Asia region. These regional guidelines were extensively revised, updated and expanded with the focus on new and additional topics of current relevance to the populations of the region. They are intended to provide guidance to national and local-level program managers and public health officials, as well as stakeholders, including health practitioners, laboratory personnel and multisectoral partners, in strategic planning, implementation, monitoring and evaluation, and strengthening the response to dengue prevention and control in their countries. Scientists and researchers involved in vaccine and antiviral drug development will also find crucial baseline information in this publication.
Dengue and Related Hemorrhagic Diseases by Susumu Hotta Pdf
Whether you're a computer novice or a computer professional, Webster's New World Computer Dictionary is one of the most useful references you can buy. It gives you clear and concise definitions for a significant number of up-to-date computer terms, including 250 that are completely new to this edition.
Positive-Strand RNA Viruses by Margo A. Brinton,Charles H. Calisher,Roland Rueckert Pdf
Positive-strand RNA viruses include the majority of the plant viruses, a number of insect viruses, and animal viruses, such as coronaviruses, togaviruses, flaviviruses, poliovirus, hepatitis C, and rhinoviruses. Works from more than 50 leading laboratories represent latest research on strategies for the control of virus diseases: molecular aspects of pathogenesis and virulence; genome replication and transcription; RNA recombination; RNA-protein interactions and host-virus interactions; protein expression and virion maturation; RNA replication; virus receptors; and virus structure and assembly. Highlights include analysis of the picornavirus IRES element, evidence for long term persistence of viral RNA in host cells, acquisition of new genes from the host and other viruses via copy-choice recombination, identification of molecular targets and use of structural and molecular biological studies for development of novel antiviral agents.
Dengue Fever and Other Hemorrhagic Viruses by Tirtha Chakraborty,I. Edward Alcamo Pdf
Dengue fever is an infectious disease found around the world that is caused by four closely related, but distinct, types of viruses commonly transmitted by Aedes aegypti mosquitoes. Triggering excessive bleeding, dengue fever, dengue hemorrhagic fever, and dengue hemorrhagic shock can be fatal. Dengue Fever and Other Hemorrhagic Viruses explores the biology of the dengue virus and similar viruses such as Ebola, Marburg virus, and Lassa fever, as well as their symptoms, where they are commonly found, how they are transmitted, and the efforts to treat and eradicate them.Chapters include: Ins and Outs of Dengue; Hemorrhagic Fevers; Vectors - Bugs That Carry Disease; The Immune System: Our Line of Defense; and, Vaccination - Waking Up the Army in Us.
Ferri's Clinical Advisor 2021 by Fred F. Ferri Pdf
Find fast answers to inform your daily diagnosis and treatment decisions! Ferri’s Clinical Advisor 2021 uses the popular "5 books in 1" format to deliver vast amounts of information in a clinically relevant, user-friendly manner. This bestselling reference has been significantly updated to provide you with easy access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, clinical algorithms, laboratory tests, and clinical practice guidelines—all carefully reviewed by experts in key clinical fields. Extensive algorithms, along with hundreds of new figures and tables, ensure that you stay current with today's medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic rhinosinusitis, subclinical brain infarction, reflux-cough syndrome, radiation pneumonitis, catatonia, end-stage renal disease, and genitourinary syndrome of menopause, among others. Includes new appendices covering common herbs in integrated medicine and herbal activities against pain and chronic diseases; palliative care; and preoperative evaluation. Offers online access to Patient Teaching Guides in both English and Spanish.
Author : WHO Regional Office for the Western Pacific Publisher : Unknown Page : 134 pages File Size : 43,8 Mb Release : 1999 Category : Medical ISBN : 9290222123
Prevention and Control of Dengue and Dengue Haemorrhagic Fever by WHO Regional Office for the Western Pacific Pdf
A comprehensive guide to the diagnosis, clinical management, epidemiological, surveillance, prevention and control of dengue and dengue haemorrhagic fever. Although guidelines and advice are universally relevant, the manual is specifically designed for use in South-East Asian countries, where dengue fever remains a major public health concern. Recommendations and advice respond to research demonstrating that different geographic areas show a variable response to infection, have different epidemiological patterns, and require different approaches to control. The book also responds to past failures to control dengue in these countries, citing almost exclusive concentration on space spraying of adult mosquitoes as one of the most important causes. With these problems in mind, the book places major emphasis on measures that can make communities responsible for vector control in the domestic environment as the best way to secure sustained improvements in prevention and control. The book has twelve chapters. The first summarizes what is known about the virus, vector, host, transmission cycle, and virus-host interactions. A brief overview of the global situation is followed by a detailed chronology of the resurgence of dengue in South-East Asia. Clinical manifestations and diagnosis are covered in chapter two, which includes precise criteria for reaching a diagnosis based on clinical manifestations and laboratory findings. Chapter three, on clinical management, gives particular attention to the management of dengue shock syndrome as a medical emergency. The important role of laboratory diagnosis is addressed in chapter four, which describes in detail the laboratory confirmatory tests that are essential for diagnosis. A chapter offering advice on the epidemiological surveillance of cases and vectors is followed by a brief description of vector distribution and bioecology. The second half of the book is devoted to strategies for prevention and control, emphasizing vector control measures that can be undertaken by communities as the best approach to successful and sustainable control. Detailed advice, supported by line drawings, checklists, and charts, is given for all appropriate environmental, biological, and chemical methods of vector control. The book also includes a chapter explaining how to develop an emergency plan for rapid response to epidemics. Further practical guidance is provided in a series of fifteen annexes, which include a model arbovirus laboratory request form, a guide to the relative sensitivity and interpretation of serological tests, and abundant advice on environmental and chemical methods of vector control specific to South-East Asia.
Cytokine Storm Syndrome by Randy Q. Cron,Edward M. Behrens Pdf
Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.
