Dermatopharmacology Of Topical Preparations Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Dermatopharmacology Of Topical Preparations book. This book definitely worth reading, it is an incredibly well-written.
Dermatopharmacology of Topical Preparations by B. Gabard,P. Elsner,C. Surber,P. Treffel Pdf
Proof of the efficacy of dermatological products is a prerequisite for clinical testing and registration. Now, efficacy claims for cosmetics must be equally substantiated. This book provides a concise, practical but comprehensive overview of experimental models used to screen, develop and select dermatological and cosmetic formulations. The authors are recognized specialists in their field and use a standardized approach to the projects facilitating the reading for the stressed scientist, for the R+D managers general view as well as for the beginners in the field.
Substances that are applied to the skin to heal it, make it feel better or improve its appearance, have much in common. They can all do damage to the skin as well as perform the task for which they were designed. They and the substances they contain are all absorbed through the skin to a greater or lesser extent. In addition, all these agents are constructed in the same general way. For these reasons it seems odd and uneconomical to consider topical pharmaceuticals, toiletry products and cosmetics separately. This was the reasoning behind the holding of a small symposium of workers involved with one or another aspect of the formulation of substances destined for application to the skin. Several aspects of the subject are covered in this book which is based on the symposium and the contents should be of interest to all who are concerned with the prescription, assess ment or formulation of topical agents. 9 1 Acne Caused and Treated by Topical Agents W. J. CUNLIFFE The four main aetiological factors involved in the development of l acne are (1) an elevated sebum excretion rate ; (2) ductal hyper 3 keratinization 2; (3) an abnormality of microbial function ; (4) host 4 inflammatory response • Although opinions differ on both sides of the Atlantic, most authorities in the United Kingdom believe that increased sebum excretion rate is the main drive to acne, there being a definitive relationship between the severity of the acne and the seborrhoea of this disease.
Dermal Drug Selection and Development by Lionel Trottet,Howard Maibach, MD Pdf
The authors show how the pharmaceutical industry faces the development of dermal drugs and provide the only book of its kind that describes how the industry develops and selects dermal drugs, complete with the challenges and opportunities of the field. Delivery of drugs through the skin has been an attractive and challenging area for research, and advances in modern technologies have resulted in a larger number of drugs being delivered transdermally, including conventional hydrophobic small molecule drugs, hydrophilic drugs and macromolecules. Offering the perspective from the industrial side of selection and development of drugs, the primary audience is geared towards the pharmaceutical industry but can also offer valuable information to clinicians, compounding pharmacists, and similarly pharmacy students. Dermal Drug Selection and Development covers the scientific gaps that exist in terms of dermal pharmacokinetics and the resulting uncertainty by clinicians when choosing a drug candidate.
Author : R. Marks Publisher : Springer Science & Business Media Page : 127 pages File Size : 46,7 Mb Release : 2012-12-06 Category : Medical ISBN : 9789400949065
Substances that are applied to the skin to heal it, make it feel better or improve its appearance, have much in common. They can all do damage to the skin as well as perform the task for which they were designed. They and the substances they contain are all absorbed through the skin to a greater or lesser extent. In addition, all these agents are constructed in the same general way. For these reasons it seems odd and uneconomical to consider topical pharmaceuticals, toiletry products and cosmetics separately. This was the reasoning behind the holding of a small symposium of workers involved with one or another aspect of the formulation of substances destined for application to the skin. Several aspects of the subject are covered in this book which is based on the symposium and the contents should be of interest to all who are concerned with the prescription, assess ment or formulation of topical agents. 9 1 Acne Caused and Treated by Topical Agents W. J. CUNLIFFE The four main aetiological factors involved in the development of l acne are (1) an elevated sebum excretion rate ; (2) ductal hyper 3 keratinization 2; (3) an abnormality of microbial function ; (4) host 4 inflammatory response • Although opinions differ on both sides of the Atlantic, most authorities in the United Kingdom believe that increased sebum excretion rate is the main drive to acne, there being a definitive relationship between the severity of the acne and the seborrhoea of this disease.
Topical Drug Bioavailability, Bioequivalence, and Penetration by Vinod P. Shah,Howard I. Maibach,John Jenner Pdf
This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations. Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs. The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.
The differential application of skin protection in occupational settings becomes increasingly complex. Due to new scientific results and technological aspects as well as European and US regulations that have to be considered in the context of cosmetics and personal protective equipment, the practical application of skin protection requires constant reviewing and improvement. This publication provides a comprehensive update on specific cosmetic products from general principles of composition, protection from specific exposures, such as irritants, allergens and ultraviolet irradiation, to safety and efficacy testing both from the perspective of in vitro and in vivo testing. The second part focusses on special requirements and practical application in high-risk occupations and the respective skin protection programs, also including some critical remarks on the limitations of currently available skin protection measures. For specialists in the field of occupational dermatology such as dermatologists, allergists, occupational physicians, industrial hygienists, toxicologists, pharmacists and cosmetic scientists, this volume provides essential information on practical application, recommendation, testing or the making of personal skin protection products.
Comprehensive Dermatologic Drug Therapy by Stephen E. Wolverton,Jashin . Wu Pdf
Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.
Author : Andreas D. Katsambas,Torello M. Lotti Publisher : Springer Science & Business Media Page : 830 pages File Size : 44,7 Mb Release : 2003-07-14 Category : Medical ISBN : 3540008780
European Handbook of Dermatological Treatments by Andreas D. Katsambas,Torello M. Lotti Pdf
Dermatology is a specialty in the field of medicine which constantly changes at a vast rate. Alongside technology, new drugs, methods and treatments are continuously developed for the treatment of all common skin diseases. The first edition of the European Handbook of Dermatological Treatments received an overwhelming response from dermatovenereologists all over Europe. Its easy-to-read format, which is also used for this 2nd edition, is aimed at helping the physician to obtain comprehensive information at a glance. The three main sections listed alphabetically define the different diseases, the drugs available and the various methods of treatment used in dermatological practice. Each chapter begins with a brief section of the aetiology and pathogenesis of the skin disease, and leads into the description of the clinical characteristics, the diagnosis and the differential diagnosis. Followed by a detailed discussion on treatment methods, alternative methods are covered as well. Each section ends with a reference list for further reading. This new edition provides an excellent update including the newest developments of drugs, methods and treatments in dermatological practice, maintaining the clear structure and well-proven format. It is a very comprehensive and practical guide and should not be missed by those treating patients with skin diseases.
Evidence-Based Dermatology by Michael Bigby,Andrew Herxheimer,Luigi Naldi,Berthold Rzany,Robert Dellavalle,Yuping Ran,Masutaka Furue Pdf
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases. Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including: • Common inflammatory skin diseases • Skin cancer, moles and actinic keratoses • Infective skin disease, exanthems and infestations • Disorders of pigmentation In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic. World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management. ‘Key Points’ accompany each chapter to provide a quick review of the most important points. Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence.
Author : Peter C. Neligan,Richard J. Warren Publisher : Elsevier Health Sciences Page : 1105 pages File Size : 55,7 Mb Release : 2012-09-05 Category : Medical ISBN : 9781455710539
Plastic Surgery - Aesthetic by Peter C. Neligan,Richard J. Warren Pdf
Fully updated to meet the demands of the 21st-century surgeon, Aesthetic Plastic Surgery, Volume 2 of Plastic Surgery, 3rd Edition, provides you with the most current knowledge and techniques in aesthetic plastic surgery, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients' expectations.
Plastic Surgery E-Book: 6 - Volume Set by Peter C. Neligan Pdf
Fully updated to meet the demands of the 21st-century surgeon, Plastic Surgery provides you with all the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Edited by Drs. Mathes and Hentz in its last edition, this six-volume plastic surgery reference now features new expert leadership, a new organization, new online features, and a vast collection of new information - delivering all the state-of-the-art know-how you need to overcome any challenge you may face. Renowned authorities provide evidence-based guidance to help you make the best clinical decisions, get the best results from each procedure, avoid complications, and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in every area of plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Master the latest on stem cell therapy, tissue engineering, and inductive therapies • aesthetic surgical techniques and nonsurgical treatments • conjoined twin separation and other craniofacial surgery advances • microsurgical lymphatic reconstruction, super microsurgery, and sternal fixation • autologous lipofilling of the breast • nerve transfers in hand surgery, hand allotransplantation, and functional prosthetics • and much, much more. Easily find the answers you need with a new organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity, plus a more templated, user-friendly, high-yield presentation. Visualize procedures more clearly through an abundance of completely redrawn full-color illustrations and new color clinical photographs. Access the complete, fully searchable contents of each volume online, download all the tables and figures, view 160 procedural videos, and take advantage of additional content and images at www.expertconsult.com!
Plastic Surgery - E-Book by Richard J Warren,Peter C. Neligan Pdf
Fully updated to meet the demands of the 21st-century surgeon, Aesthetic Plastic Surgery, Volume 2 of Plastic Surgery, 3rd Edition, provides you with the most current knowledge and techniques in aesthetic plastic surgery, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in aesthetic plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Purchase this volume individually or own the entire set, with the ability to search across all six volumes online! Master the latest nonsurgical aesthetic therapies, including cosmetic skin care, Botulinum toxin treatments, soft tissue fillers, and skin resurfacing. Apply the most recent techniques in rhinoplasty, body contouring, facelift techniques, and the growing field of Asian facial cosmetic surgery. Know what to look for and what results you can expect with over 1,400 photographs and illustrations. See how to perform key techniques with 41 surgical videos online. Access the complete, fully searchable contents online, download all the tables and figures, and take advantage of additional content and images at www.expertconsult.com!
Handbook of Cosmetic Science and Technology, Fourth Edition by André O. Barel,Marc Paye,Howard I. Maibach Pdf
Written by experienced and internationally renowned contributors, this is the fourth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for skin, hair, and nails. New to this fourth edition are chapters on dermatocosmetic vehicles, surface film, causes and measurement of skin aging, make-up products, skin healing, cosmetics in sports, cosmetotextiles, nutricosmetics, natural ingredients, cosmeceuticals, and regulatory vigilance.
The Epidermis in Wound Healing by David T. Rovee,Howard I. Maibach Pdf
New biological techniques and a revival of interest in both acute and chronic wound healing have led to an enormously improved understanding of the cellular and chemical complexities of the healing process. Exciting developments in the evolution of epidermal biology are creating new opportunities for research and clinical applications in wound heal
Alternatives for Dermal Toxicity Testing by Chantra Eskes,Erwin van Vliet,Howard I. Maibach Pdf
This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.