Design And Modeling Of Semiconductor Terahertz And Infrared Sensing Structures For Protein Characterization

Author : Maximilian Bettenhausen
Publisher : BoD – Books on Demand
Page : 162 pages
File Size : 40,8 Mb
Release : 2020-01-01
Category : Technology & Engineering
ISBN : 9783737609104

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Design and Modeling of Semiconductor Terahertz and Infrared Sensing Structures for Protein Characterization by Maximilian Bettenhausen Pdf

Das Gebiet der Bio-Sensorik wird für die Medizin und die biologische Grundlagenforschung immer bedeutender. In diesen Bereichen ist die Untersuchung charakteristischer Eigenschaften von Membranproteinen unerlässlich, da sie die Kommunikation und Aktivität biologischer Zellen verantworten. Darüber hinaus steuern sie den Transport verschiedener Substanzen in die Zelle und eignen sich als Ziel von Medikamenten. Diese Art von Proteinen weisen charakterisitsche Resonanzen zwischen 200GHz und 2 THz auf. In dieser Arbeit wird das Design von gekoppelten plasmonischen THz-Antennen gezeigt. Diese Antennen bestehen aus hochdotiertem Germanium auf einem Siliziumsubstrat und verfügen über eine Resonanzfrequenz von 500 GHz. Sie bieten eine hohe Empfindlichkeit für dünne Schichten in einer wässrigen Lösung und eignen sich für die Charakterisierung von Proteinen im THz-Bereich. Der Entwurf dieser Antennen wird mithilfe von Finite-Elemente-Simulationen durchgeführt. Da solch ein Entwurf einen hohen Rechenaufwand umfasst, wird ein weiterer Ansatz gezeigt. Die plasmonische Antenne wird als RLC-Schwingkreis beschrieben, was Designs mit analytischen Berechnungen ermöglicht. Aufgrund dieser Berschreibung kann eine Anpassung der Impedanz zwischen Antenne und Biomolekül durchgeführt werden, wodurch die Struktur weiter optimiert wird. Neben dem THz-Bereich wird auch der Infrarot-Bereich untersucht. Dort sind Proteinbindungsprozesse zu beobachten. In dieser Arbeit wird eine neuartige Struktur untersucht, um die Brechungsindexdispersion von Proteinen zu messen. Für diese Untersuchung wird ein Array aus Silizium-Mikrosäulen analysiert. Sie zeigen eine hohe Sensitivität für sehr dünne Schichten. Die Ergebnisse dieser Arbeit zeigen, dass sich die untersuchten Sensorstrukturen für die Charakterisierung von Membranproteinen im THz- und Infrarot-Bereich sehr gut eignen. Weiterin sind sie kompatibel zu BiCMOS Prozessen und ermöglichen die kostengünstige Herstellung von Lab-on-Chip Architekturen.

Author : National Institute of Standards and Technology (U.S.)
Publisher : Unknown
Page : 1162 pages
File Size : 43,9 Mb
Release : 1994
Category : Electronic
ISBN : OSU:32435067293787

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Publications of the National Institute of Standards and Technology ... Catalog by National Institute of Standards and Technology (U.S.) Pdf

Author : G¿nter Gauglitz,David S. Moore
Publisher : John Wiley & Sons
Page : 2011 pages
File Size : 42,7 Mb
Release : 2014-06-09
Category : Science
ISBN : 9783527321506

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Handbook of Spectroscopy by G¿nter Gauglitz,David S. Moore Pdf

This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Author : Anonim
Publisher : Unknown
Page : 614 pages
File Size : 48,6 Mb
Release : 1998
Category : Aeronautics
ISBN : STANFORD:36105021106708

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International Aerospace Abstracts by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 800 pages
File Size : 51,8 Mb
Release : 2008
Category : Dissertations, Academic
ISBN : STANFORD:36105132702577

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Dissertation Abstracts International by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 2540 pages
File Size : 44,5 Mb
Release : 2002
Category : Chemistry
ISBN : UOM:39015057321377

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Chemical Abstracts by Anonim Pdf

Author : Susan L. Dexheimer
Publisher : CRC Press
Page : 358 pages
File Size : 48,9 Mb
Release : 2017-12-19
Category : Technology & Engineering
ISBN : 9781420007701

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Terahertz Spectroscopy by Susan L. Dexheimer Pdf

The development of new sources and methods in the terahertz spectral range has generated intense interest in terahertz spectroscopy and its application in an array of fields. Presenting state-of-the-art terahertz spectroscopic techniques, Terahertz Spectroscopy: Principles and Applications focuses on time-domain methods based on femtosecond laser sources and important recent applications in physics, materials science, chemistry, and biomedicine. The first section of the book examines instrumentation and methods for terahertz spectroscopy. It provides a comprehensive treatment of time-domain terahertz spectroscopic measurements, including methods for the generation and detection of terahertz radiation, methods for determining optical constants from time-domain measurements, and the use of femtosecond time-resolved techniques. The last two sections explore a variety of applications of terahertz spectroscopy in physics, materials science, chemistry, and biomedicine. With chapters contributed by leading experts in academia, industry, and research, this volume thoroughly discusses methods and applications, setting it apart from other recent books in this emerging terahertz field.

Author : Chandan Kumar Sarkar
Publisher : CRC Press
Page : 462 pages
File Size : 51,8 Mb
Release : 2018-09-03
Category : Technology & Engineering
ISBN : 9781466512665

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Technology Computer Aided Design by Chandan Kumar Sarkar Pdf

Responding to recent developments and a growing VLSI circuit manufacturing market, Technology Computer Aided Design: Simulation for VLSI MOSFET examines advanced MOSFET processes and devices through TCAD numerical simulations. The book provides a balanced summary of TCAD and MOSFET basic concepts, equations, physics, and new technologies related to TCAD and MOSFET. A firm grasp of these concepts allows for the design of better models, thus streamlining the design process, saving time and money. This book places emphasis on the importance of modeling and simulations of VLSI MOS transistors and TCAD software. Providing background concepts involved in the TCAD simulation of MOSFET devices, it presents concepts in a simplified manner, frequently using comparisons to everyday-life experiences. The book then explains concepts in depth, with required mathematics and program code. This book also details the classical semiconductor physics for understanding the principle of operations for VLSI MOS transistors, illustrates recent developments in the area of MOSFET and other electronic devices, and analyzes the evolution of the role of modeling and simulation of MOSFET. It also provides exposure to the two most commercially popular TCAD simulation tools Silvaco and Sentaurus. • Emphasizes the need for TCAD simulation to be included within VLSI design flow for nano-scale integrated circuits • Introduces the advantages of TCAD simulations for device and process technology characterization • Presents the fundamental physics and mathematics incorporated in the TCAD tools • Includes popular commercial TCAD simulation tools (Silvaco and Sentaurus) • Provides characterization of performances of VLSI MOSFETs through TCAD tools • Offers familiarization to compact modeling for VLSI circuit simulation R&D cost and time for electronic product development is drastically reduced by taking advantage of TCAD tools, making it indispensable for modern VLSI device technologies. They provide a means to characterize the MOS transistors and improve the VLSI circuit simulation procedure. The comprehensive information and systematic approach to design, characterization, fabrication, and computation of VLSI MOS transistor through TCAD tools presented in this book provides a thorough foundation for the development of models that simplify the design verification process and make it cost effective.

Author : Anonim
Publisher : Unknown
Page : 806 pages
File Size : 47,7 Mb
Release : 1995
Category : Science
ISBN : UOM:39015053419712

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Government Reports Announcements & Index by Anonim Pdf

Author : Jamal Uddin
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 51,6 Mb
Release : 2017-03-13
Category : Technology & Engineering
ISBN : 9789535130314

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Terahertz Spectroscopy by Jamal Uddin Pdf

The terahertz regime of the electromagnetic spectrum was largely unexplored due to the lack of technology needed to generate and detect the radiation. However, in the last couple of decades, there has been a dramatic increase in tools needed to harness the radiation. This remarkable progress made in the development of terahertz sources, components, and detectors has resulted in an ever-increasing inquisitiveness of the applications of terahertz technology in a wide range of fields including medicine, pharmaceuticals, security, sensing, and quality assurance. This book, Terahertz Spectroscopy - A Cutting Edge Technology, presents an overview of the recent advances in terahertz technology and their application in a vast array of fields. The scientists and students are encouraged to read and share the content of this volume. The book also provides a good starting point for researchers who are new to the terahertz regime. The various chapters of the book have been written by renowned scientists in different parts of the world who are at the forefront of terahertz research fields. It is our (InTech publisher, editor, and authors) hope that this book will enhance knowledge and stimulate more interest and future research in terahertz technology.

Author : National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Revealing Chemistry through Advanced Chemical Imaging
Publisher : National Academies Press
Page : 222 pages
File Size : 51,5 Mb
Release : 2006-06-01
Category : Science
ISBN : 9780309164634

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Visualizing Chemistry by National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Revealing Chemistry through Advanced Chemical Imaging Pdf

Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Author : R.E. Miles,X.-C. Zhang,H. Eisele,A. Krotkus
Publisher : Springer Science & Business Media
Page : 365 pages
File Size : 48,5 Mb
Release : 2007-09-08
Category : Technology & Engineering
ISBN : 9781402065033

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Terahertz Frequency Detection and Identification of Materials and Objects by R.E. Miles,X.-C. Zhang,H. Eisele,A. Krotkus Pdf

Want an overview of where the technology of terahertz detection has been going? Here it is. The technology has largely been developed around expensive and bulky femtosecond laser systems but, as described in this book, advances in semiconductor superlattice technology are leading to compact "electronic" sources such as the quantum cascade laser, two-terminal "Gunn" type oscillators and even a THz frequency amplifier. These advances towards electronic (as opposed to optical) THz systems mean that the technology will become portable and much less costly.

Author : Dwight L. Woolard
Publisher : World Scientific
Page : 261 pages
File Size : 51,9 Mb
Release : 2007
Category : Technology & Engineering
ISBN : 9789812771803

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Terahertz Science and Technology for Military and Security Applications by Dwight L. Woolard Pdf

The inherent advantages and potential payoffs of the terahertz (THz) regime for military and security applications serve as an important driver for interest in new THz-related science and technology. In particular, the very rapid growth in more recent years is arguably most closely linked to the potential payoffs of THz sensing and imaging (THz-S&I). This book presents some of the leading fundamental research efforts towards the realization of practical THz-S&I capabilities for military and security applications. Relevant subjects include theoretical prediction and/or measurement of THz spectroscopic phenomenon in solid-state materials such as high explosives (e.g. HMX, PETN, RDX, TNT, etc.), carbon-fiber composites, biological agents (e.g. DNA, RNA, proteins, amino acids) and organic-semiconductor nanostructures. Individual papers also address the effective utilization of state-of-the-art THz-frequency technology in military and security relevant scenarios such as standoff S&I, screening of packages and personnel, and perimeter defense. Technical papers introduce novel devices and/or concepts that enhance THz source and detector performance, enabling completely new types of sensor functionality at THz frequency (e.g. detection at nanoscale/molecular levels), and defining new and innovative sensing modalities (e.g. remote personnel identification) for defense and security. Therefore, the collective research presented here represents a valuable source of information on the evolving field of THz-S&I for military and security applications. Sample Chapter(s). Foreword (106 KB). Chapter 1: Development of Computational Methodologies for the Prediction and Analysis of Solid-State Terahertz Spectra (1,347 KB). Contents: Fire Damage on Carbon Fiber Materials Characterized by THz Waves (N Karpowicz et al.); Fingerprinting Insulins in the Spectral Region from Mid-IR to THz (R Song et al.); Ambient Air Used as the Nonlinear Media for THz Wave Generation (X Xie et al.); Time Domain Terahertz Imaging of Threats in Luggage and Personnel (D Zimdars et al.); Designed Self-Organization for Molecular Optoelectronic Sensors (M Norton); An Optically-Triggered I-RTD Hybrid THz Oscillator Design (D Woolard et al.); New Technique to Suppress Sidelobe Clutter in Perimeter Security Systems (G W Webb et al.); Remote Identification of Foreign Subjects (A Sokolnikov); and other papers. Readership: University researchers in electrical engineering, physics, chemistry, biology; students and small business efforts in high-frequency electronics and sensors; as a supplement for graduate courses.

Author : J.R. Durig
Publisher : Springer Science & Business Media
Page : 605 pages
File Size : 55,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400990708

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Analytical Applications of FT-IR to Molecular and Biological Systems by J.R. Durig Pdf

In the past few years it has become apparent that Fourier Trans form infrared spectroscopy is developing into an excellent technique for solving some of the very difficult problems encountered in analytical chemistry. The applications of FT-IR include the detec tion and identification of chemical components separated by gas chromatography techniques, determination of low concentration com ponents in a mixture, and problems which have energy limitations such as water samples, opaque samples and biological systems. The lectures presented in this volume will be utilized at the NATO Advanced Study Institute in Florence, Italy from August 31 to September 12, 1980. These lectures are divided into three main sections: Instrumentation and Theory, Techniques, and Applications. The first section includes a basic introduction to interferometry and the operating parameters. The Techniques section consists of several lectures on accessories used in FT-IR, software and data systems, and special handling techniqucs. The third section con tains an abundance of information on the applications of the FT-IR technique to inorganic and organic molecules, polymers, biological systems, solids and to the determination of molecular structures and conformational analyses. The contents of this volume should provide the reader with the present applications in this field as well as an indication of possible future trends. In gcneral the lectures are of a pedagogical nature and are not to be considered as review articles.

Author : Wei Wang,Christopher J. Roberts
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 52,8 Mb
Release : 2010-12-28
Category : Medical
ISBN : 9781118043585

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Aggregation of Therapeutic Proteins by Wei Wang,Christopher J. Roberts Pdf

This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.