Design Synthesis Multifunctionalization And Biomedical Applications Of Multifunctional Mesoporous Silica Based Drug Delivery Nanosystems

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Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems

Yu Chen
Design Synthesis Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica Based Drug Delivery Nanosystems Book PDF

Author : Yu Chen
Publisher : Springer
Page : 88 pages
File Size : 55,6 Mb
Release : 2015-10-14
Category : Technology & Engineering
ISBN : 9783662486221

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Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems by Yu Chen Pdf

This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.

Hybrid Organic-Inorganic Interfaces

Marie Helene Delville,Andreas Taubert
Hybrid Organic Inorganic Interfaces Book PDF

Author : Marie Helene Delville,Andreas Taubert
Publisher : John Wiley & Sons
Page : 1010 pages
File Size : 49,9 Mb
Release : 2018-04-09
Category : Technology & Engineering
ISBN : 9783527342556

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Hybrid Organic-Inorganic Interfaces by Marie Helene Delville,Andreas Taubert Pdf

Hybrid organic-inorganic materials and the rational design of their interfaces open up the access to a wide spectrum of functionalities not achievable with traditional concepts of materials science. This innovative class of materials has a major impact in many application domains such as optics, electronics, mechanics, energy storage and conversion, protective coatings, catalysis, sensing and nanomedicine. The properties of these materials do not only depend on the chemical structure, and the mutual interaction between their nano-scale building blocks, but are also strongly influenced by the interfaces they share. This handbook focuses on the most recent investigations concerning the design, control, and dynamics of hybrid organic-inorganic interfaces, covering: (i) characterization methods of interfaces, (ii) innovative computational approaches and simulation of interaction processes, (iii) in-situ studies of dynamic aspects controlling the formation of these interfaces, and (iv) the role of the interface for process optimization, devices, and applications in such areas as optics, electronics, energy and medicine.

Update on Silica-based Mesoporous Materials for Biomedical Applications

Luigi Pasqua
Update on Silica based Mesoporous Materials for Biomedical Applications Book PDF

Author : Luigi Pasqua
Publisher : Smithers Rapra
Page : 182 pages
File Size : 41,6 Mb
Release : 2011-11-22
Category : Medical
ISBN : 9781847355096

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Update on Silica-based Mesoporous Materials for Biomedical Applications by Luigi Pasqua Pdf

This book provides an insightful understanding of the mesoporous silica structure and its special properties. The details of synthesis and modification strategies are discussed by reviewing the open literature. The discussion concerning the potential of mesoporous silica in modern biomedical applications will be related to a critical analysis in the field of material science. This book will help the reader rapidly develop the necessary tools to follow the design of the different mesoporous silica-based devices presented in the various studies. The structure of the different devices is examined in detail and the relationship between the structure and the expected activity are discussed. It will also assist in the ability to design new therapeutic devices in a field where the applications seem to be without limits.

Mesoporous Silica-based Nanomaterials and Biomedical Applications -

Anonim
Mesoporous Silica based Nanomaterials and Biomedical Applications Book PDF

Author : Anonim
Publisher : Academic Press
Page : 226 pages
File Size : 41,5 Mb
Release : 2018-09-20
Category : Science
ISBN : 9780128155219

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Mesoporous Silica-based Nanomaterials and Biomedical Applications - by Anonim Pdf

Cancer Therapy and Diagnosis, Part A, Volume 43 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN). Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series Updated release includes the latest information on Cancer Therapy and Diagnosis

Novel Platforms for Drug Delivery Applications

Sangita Das,Sabu Thomas,Partha Pratim Das
Novel Platforms for Drug Delivery Applications Book PDF

Author : Sangita Das,Sabu Thomas,Partha Pratim Das
Publisher : Woodhead Publishing
Page : 695 pages
File Size : 52,9 Mb
Release : 2022-11-08
Category : Medical
ISBN : 9780323913782

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Novel Platforms for Drug Delivery Applications by Sangita Das,Sabu Thomas,Partha Pratim Das Pdf

Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology. Provides an up-to-date single resource on novel drug delivery platforms, a rapidly evolving field of research Covers a broad range of materials, systems and release mechanisms, including in vivo and in vitro studies Describes the synthesis, properties, formulation and application of various novel drug delivery systems

Advances in Nanotechnology-Based Drug Delivery Systems

Anupam Das Talukdar,Satyajit Dey Sarker,Jayanta Kumar Patra
Advances in Nanotechnology Based Drug Delivery Systems Book PDF

Author : Anupam Das Talukdar,Satyajit Dey Sarker,Jayanta Kumar Patra
Publisher : Elsevier
Page : 672 pages
File Size : 49,5 Mb
Release : 2022-06-06
Category : Technology & Engineering
ISBN : 9780323904148

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Advances in Nanotechnology-Based Drug Delivery Systems by Anupam Das Talukdar,Satyajit Dey Sarker,Jayanta Kumar Patra Pdf

Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems“/li> Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more

Hydrogels

Thakur Raghu Raj Singh,Garry Laverty,Ryan Donnelly
Hydrogels Book PDF

Author : Thakur Raghu Raj Singh,Garry Laverty,Ryan Donnelly
Publisher : CRC Press
Page : 309 pages
File Size : 43,5 Mb
Release : 2018-02-28
Category : Medical
ISBN : 9781351648271

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Hydrogels by Thakur Raghu Raj Singh,Garry Laverty,Ryan Donnelly Pdf

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

Drug Delivery Nanosystems for Biomedical Applications

Chandra P Sharma
Drug Delivery Nanosystems for Biomedical Applications Book PDF

Author : Chandra P Sharma
Publisher : Elsevier
Page : 451 pages
File Size : 54,8 Mb
Release : 2018-08-22
Category : Medical
ISBN : 9780323509237

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Drug Delivery Nanosystems for Biomedical Applications by Chandra P Sharma Pdf

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

Biomedical Applications of Mesoporous Ceramics

María Vallet-Regí,Miguel Manzano García,Montserrat Colilla
Biomedical Applications of Mesoporous Ceramics Book PDF

Author : María Vallet-Regí,Miguel Manzano García,Montserrat Colilla
Publisher : CRC Press
Page : 245 pages
File Size : 51,7 Mb
Release : 2012-11-28
Category : Medical
ISBN : 9781439883075

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Biomedical Applications of Mesoporous Ceramics by María Vallet-Regí,Miguel Manzano García,Montserrat Colilla Pdf

Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number of publications. As controlled drug delivery systems are one of the most promising applications for human health care, it is now necessary to set the milestones of this technology, from the very basic to the most advanced. Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering is a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The book provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials and bone tissue engineering, detailing the research and development of these biomedical applications.

Mesoporous Materials for Drug Delivery and Theranostics

Valentina Cauda,Giancarlo Canavese
Mesoporous Materials for Drug Delivery and Theranostics Book PDF

Author : Valentina Cauda,Giancarlo Canavese
Publisher : MDPI
Page : 204 pages
File Size : 51,9 Mb
Release : 2020-12-17
Category : Science
ISBN : 9783039439393

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Mesoporous Materials for Drug Delivery and Theranostics by Valentina Cauda,Giancarlo Canavese Pdf

Mesoporous materials are capturing great interest thanks to their exceptional surface area, uniform and tunable pore size, ease surface functionalization, thus enabling broad series of intervention in the field of nanomedicine. Since many years, these aspects foster a deep investigation on mesoporous nanoparticles, to design and fabricate biocompatible, smart and stimuli-responsive nanotools for controlled drug- or gene-delivery, theranostics applications, in particular for cancer therapy, and tissue engineering. This Book is thus dedicated to the most recent advances in the field, collecting research papers and reviews. It spans from the synthesis and characterization of the mesoporous material, especially those made of silica, silicon and bioactive glasses, to their functionalization with smart gate-keepers, reporter molecules or targeting ligands, up to their in-vitro applications in the nanomedicine field.

Smart Polymeric Nano-Constructs in Drug Delivery

Suresh P Vyas,Udita Agrawal,Rajeev Sharma
Smart Polymeric Nano Constructs in Drug Delivery Book PDF

Author : Suresh P Vyas,Udita Agrawal,Rajeev Sharma
Publisher : Academic Press
Page : 626 pages
File Size : 46,7 Mb
Release : 2022-11-12
Category : Business & Economics
ISBN : 9780323913997

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Smart Polymeric Nano-Constructs in Drug Delivery by Suresh P Vyas,Udita Agrawal,Rajeev Sharma Pdf

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. Provides comprehensive overview of the potential role of polymeric systems in drug delivery Explores the design, synthesis, and application of different smart material-based delivery systems Includes fundamental and clinical applications

Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics

Ravichandran Manisekaran
Design and Evaluation of Plasmonic Magnetic Au MFe2O4 M Fe Co Mn Core Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics Book PDF

Author : Ravichandran Manisekaran
Publisher : Springer
Page : 168 pages
File Size : 48,9 Mb
Release : 2017-10-30
Category : Technology & Engineering
ISBN : 9783319676098

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Design and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics by Ravichandran Manisekaran Pdf

This thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.

Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications

Hriday Bera,Chowdhury Mobaswar Hossain,Sudipta Saha
Biopolymer Based Nanomaterials in Drug Delivery and Biomedical Applications Book PDF

Author : Hriday Bera,Chowdhury Mobaswar Hossain,Sudipta Saha
Publisher : Academic Press
Page : 630 pages
File Size : 42,5 Mb
Release : 2021-01-05
Category : Business & Economics
ISBN : 9780128208755

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Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications by Hriday Bera,Chowdhury Mobaswar Hossain,Sudipta Saha Pdf

Over the past few decades, there has been unprecedented progress in the design of versatile biopolymer-based nanoplatforms for pharmaceutical and biomedical applications, particularly due to their attractive traits, including excellent biocompatibility, outstanding biodegradability, low immunogenicity, and facile chemical modifiability. Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications serves as a clear and detailed body of information on the synthesis and characterization of biopolymer-based materials in nanomedicine. This book describes various nanomaterials consisting of biopolymers including polysaccharides (i.e., derived from plants, animals, bacteria, algae, and fungi) and polypeptides in terms of their structures, synthetic protocols, and characterization and uses as therapeutic drugs and gene delivery carriers and in other biomedical fields. The chapters of this book, which are contributed by internationally renowned scholars working in the arena of biopolymer-based nanomaterials, would offer a wide vision on the potential future applications of these nanomaterials in the delivery and targeting of bioactive molecules of pharmaceutical interests and in tissue engineering, biosensing, bioimaging, and diagnostic purposes. The state-of-the-art information presented in the book would also encourage young investigators and researchers to further bring cutting-edge developments in the field of nanomedicine in the near future. Provides a scholarly insight into the recent development of biopolymer-based nanomaterials Focuses on the diverse cutting-edge techniques for the fabrication of native and modified biopolymer-based nanoplatforms and their applications in drug delivery and biomedical fields Assesses the opportunities and challenges of biopolymer-based nanocarriers in pharmaceutical and biomedical research

Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II)

Surendra Nimesh,Nidhi Gupta,Ramesh Chandra
Nanomaterials Evolution and Advancement towards Therapeutic Drug Delivery Part II Book PDF

Author : Surendra Nimesh,Nidhi Gupta,Ramesh Chandra
Publisher : Bentham Science Publishers
Page : 321 pages
File Size : 40,8 Mb
Release : 2021-06-02
Category : Science
ISBN : 9781681088242

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Nanomaterials: Evolution and Advancement towards Therapeutic Drug Delivery (Part II) by Surendra Nimesh,Nidhi Gupta,Ramesh Chandra Pdf

The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. Part II covers the following topics: · Solid lipid nanoparticles and nanostructured lipid carriers · Silica based nanomaterials · Hydrogels · Metallic nanoparticles · Computational and experimental binding interactions of drug and β-cyclodextrin · Clinical milestones in nanotherapeutics · Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Nano- and Microscale Drug Delivery Systems

Alexandru Mihai Grumezescu
Nano and Microscale Drug Delivery Systems Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 514 pages
File Size : 47,5 Mb
Release : 2017-03-27
Category : Medical
ISBN : 9780323527286

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Nano- and Microscale Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems. Shows how micro- and nanomaterials can be engineered to create more effective drug delivery systems Summarizes current nanotechnology research in the field of drug delivery systems Explores the pros and cons of using particular nanomaterials as therapeutic agents Serves as a valuable reference for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems